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The map label for this gene is ftsX [H]

Identifier: 195977855

GI number: 195977855

Start: 752890

End: 753735

Strand: Direct

Name: ftsX [H]

Synonym: Sez_0723

Alternate gene names: 195977855

Gene position: 752890-753735 (Clockwise)

Preceding gene: 195977854

Following gene: 195977857

Centisome position: 37.19

GC content: 43.5

Gene sequence:

>846_bases
ATGGTGACCGTCACCTTAACCCTGCTTGGGGTCTTTGCTGCAACCCTGCTGAACATTCAACGTGTCGCTTCTGGCGTGGA
AAACAACATTCAAATCAATGCTTATTTGCAGGTTGATTCGACAGATGCTGCCAAGGTGGTTCAGTCGATTAATGGAGAGC
AGGTGAATAACGAGAATTACCATAAGATTTATGATCAGATTGCAGGGCTAAAGGGCGTTGAGAGGATTATTTTCTCAAGC
AAGGACGAGCAGCTGCAAAAGCTACAGGATAGCCTGGGCGATGTCTGGGGCATGTACAACGAGGACAGCAATCCCCTGCA
AGACATCTATATCGTGGAAACCAAGACCCCTAAGCAGGTCAAATCAGTCACTAAGGCTATCAAAAAGATTCAAGGGATTG
AAGATGCGGACTATGGTGGTATCAATTCGGATAAGCTCTTTAAGTTTTCAAAGCTGATCCAAACATGGGGCATTATTGGA
ACACTGTTGCTCTTGTTTATCGCAATCTTTCTGATTTCCAATACCATTCGCATGACTATCATGTCTCGTCAGCGCGATAT
TGCGATCATGCGTCTGGTTGGTGCGAAAAATTCCTATATTCGTGGCCCATTCTTTTTTGAAGGGGCTTGGGTTGGTCTGC
TTGGTGCGATATTGCCATCGTTGATTCTTTATTATGGCTACGAGTTTGCCTACAAGCATTTTACCCCGGAATTGCAGCAT
AATAGCCTGTCTATGTACCCTATCAATCCATATGTTTATTACTTGATTGGTCTGCTTTTTGTGATTGGTATTATCATTGG
ATCACTAGGGTCAGTCTTATCTATGAGACGCTACCTTAAGTTTTAA

Upstream 100 bases:

>100_bases
GGAGACTATGGTTACGATGATTAGACATTTTTTCCGTCATATCTGGGAATCTATCAAAAATTTAAGGCGTAATCTCCTCA
TGACCTTTGCGTCAGTCAGT

Downstream 100 bases:

>100_bases
TCTAAAAGAGCCTTTTGCCTGTGTGCCTCGGCTGGCACCTTGCAGCAAGAGCTCTTTTTTGTTTGTCTAGGCAATACGTG
CTAGGTAAACAACAACAGAG

Product: cell division protein FtsX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MVTVTLTLLGVFAATLLNIQRVASGVENNIQINAYLQVDSTDAAKVVQSINGEQVNNENYHKIYDQIAGLKGVERIIFSS
KDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQGIEDADYGGINSDKLFKFSKLIQTWGIIG
TLLLLFIAIFLISNTIRMTIMSRQRDIAIMRLVGAKNSYIRGPFFFEGAWVGLLGAILPSLILYYGYEFAYKHFTPELQH
NSLSMYPINPYVYYLIGLLFVIGIIIGSLGSVLSMRRYLKF

Sequences:

>Translated_281_residues
MVTVTLTLLGVFAATLLNIQRVASGVENNIQINAYLQVDSTDAAKVVQSINGEQVNNENYHKIYDQIAGLKGVERIIFSS
KDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQGIEDADYGGINSDKLFKFSKLIQTWGIIG
TLLLLFIAIFLISNTIRMTIMSRQRDIAIMRLVGAKNSYIRGPFFFEGAWVGLLGAILPSLILYYGYEFAYKHFTPELQH
NSLSMYPINPYVYYLIGLLFVIGIIIGSLGSVLSMRRYLKF
>Mature_281_residues
MVTVTLTLLGVFAATLLNIQRVASGVENNIQINAYLQVDSTDAAKVVQSINGEQVNNENYHKIYDQIAGLKGVERIIFSS
KDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQGIEDADYGGINSDKLFKFSKLIQTWGIIG
TLLLLFIAIFLISNTIRMTIMSRQRDIAIMRLVGAKNSYIRGPFFFEGAWVGLLGAILPSLILYYGYEFAYKHFTPELQH
NSLSMYPINPYVYYLIGLLFVIGIIIGSLGSVLSMRRYLKF

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789872, Length=228, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 31659; Mature: 31659

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTVTLTLLGVFAATLLNIQRVASGVENNIQINAYLQVDSTDAAKVVQSINGEQVNNENY
CEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHCCCCCCCCCHH
HKIYDQIAGLKGVERIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQV
HHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHH
KSVTKAIKKIQGIEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTI
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSRQRDIAIMRLVGAKNSYIRGPFFFEGAWVGLLGAILPSLILYYGYEFAYKHFTPELQH
HHCCHHHHHHHHHCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NSLSMYPINPYVYYLIGLLFVIGIIIGSLGSVLSMRRYLKF
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVTVTLTLLGVFAATLLNIQRVASGVENNIQINAYLQVDSTDAAKVVQSINGEQVNNENY
CEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHCCCCCCCCCHH
HKIYDQIAGLKGVERIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQV
HHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHH
KSVTKAIKKIQGIEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTI
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSRQRDIAIMRLVGAKNSYIRGPFFFEGAWVGLLGAILPSLILYYGYEFAYKHFTPELQH
HHCCHHHHHHHHHCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NSLSMYPINPYVYYLIGLLFVIGIIIGSLGSVLSMRRYLKF
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]