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The map label for this gene is map [H]

Identifier: 195977831

GI number: 195977831

Start: 725467

End: 727266

Strand: Direct

Name: map [H]

Synonym: Sez_0699

Alternate gene names: 195977831

Gene position: 725467-727266 (Clockwise)

Preceding gene: 195977830

Following gene: 195977832

Centisome position: 35.84

GC content: 42.39

Gene sequence:

>1800_bases
ATGATAACATTAAAATCTGCGCGTGAAATAGAAGCTATGGATAGGGCAGGAGACTTTCTTGCTGGGATTCATATTGGCCT
CAGACAGATCATTAAGCCTGGGGTTGACATGTGGGAGGTCGAAGAATATGTGCGCAGGCGCTGCAAGGAAGACAATGTGC
TTCCTTTACAGATTGGTGTTGATGGCCAATTAATGGACTATCCCTATGCTACCTGCTGCGGGCTAAATGATGAGGTTGCA
CATGCTTTTCCGCGCCATTATATTCTAAAGGAAGGGGATTTGCTTAAGGTAGATATGGTGCTAAGCGAGCCACTTGATAA
GGCTGTCGTTGATGTAGCGGCCTTGGATTTTGATAATGTGGCAGAAATGAAGAAGTGGACAGAATCTTATACAGGTGGTT
TGGCTGATTCCTGCTGGGCTTATGCTGTAGGTACACCGTCTGATGAGGTCAAAAGGCTGATGGACGTGACCAAGGAAGCC
ATGTATCGTGGGATCGAGCAGGCAGTTGTGGGGAACCGCATTGGTGACATTGGTGCAGCAGTCCAGCAATATGCTGAAAG
TCATGGCTACGGTGTGGTTCGAGACCTTGTTGGTCATGGTGTTGGACCAACCATGCACGAAGAGCCGATGGTGCCTAACT
ATGGTACAGCAGGAAGAGGACTACGTCTGAAGGAGGGCATGGTGCTCACCGTAGAGCCGATGATCAATACTGGCACATGG
GAAATTGATACAGATATGAAAACAGGCTGGGCCCATAAAACACTTGATGGTGGCTTGTCCTGCCAGTATGAGCATCAATT
TGTGATTACAAAGGATGGTCCAGTGATTTTAACTAGTCAGGCGAAGAAAGAACTTATTAGAATGTCAATAAAGAAATTCT
TGGACAAGGTCATATCAAAATGGCAATATGAGCCAATCCAAGCCTTTATGCGCCATTTTCAGAGTGCAGAGATGGATTTG
TCAGCGATCGCAGTTGCTTATTACCTTATTTTGACAGCCTTTCCACTCATTGTTATTGCGGCTAATATTTTTCCTTATTT
AAATATTGATATTTCAGACTTATTACGCTTAATGAAGGAGCAATTGCCTAAGGATATTTATCGCTCTGCCTCCTCTATTG
TGGTTAATATTTTTTCCAAGCCATCAGGAGGTGTCTTAGGAATAGCTACCTTGACAGGACTTTGGACAATGTCACGAAGC
CTAGCCTCTTTACAAAAGGCCTTTAATAAGGCCTATGATGCTTCTGAGCATCGTGATTTTTTGCTTGGTCATTTGGTAGG
CTTACTGACCAGCCTGCTGATTCTGTTTTTGTTGACCTTTGCCTTGATTTTTTCAACCTTTTCTAAGGCAGCGATTCAGG
TGCTGGATAGGCATTATCATTTAAATGACAATATCACGACGCTCTTTTTATTCTTGATCCAGCCGATTACGATTTTGATT
ATATTTATTGGTCTGATGCTACTTTATTTTTTGTTACCAAATATCAAAATCAAGAAAATCAGGTATATCTTACCAGGAAC
ATTTTTTACCACCTTTGTCATGATTTTTTTGAGCAATATGGTTGGTAATTATGTGGTACATAATGTGGAGCGAATGGTCG
ATATTAAAACCTTTGGTTCGGTCATGGTTTTTATTATCATGCTGTGGTTTATTTTCCTGGCAAGGATATTGATTATGGGG
GCAGTTTTTAATGCTACCTACCAAGAGCTATCCATCGGCAAATTAGAGGGACGCAGCGGTAATGTTGTTTCTCTCATCAA
AAAGACATTAGGCAATGATGGTGCGCCGCCCAAGAAATAG

Upstream 100 bases:

>100_bases
AGAAGAAGCAGTACACTTGATATGGAGGTCATGGTTGATGATCAGGTGATTGCTAAAGCCATTATTACAACTAAGCTTAA
TTAGAGGAGAAACAAAAACA

Downstream 100 bases:

>100_bases
CGGCTTGTCTTAGAATGAAAAACAAGACGGTGCTTGGTGATTAGTTGATGGGGTAAGGGCCCTTGTCCTTACTTCATTTT
CTTTTATTTGCTTTGCTGAG

Product: methionine aminopeptidase Map

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYVRRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVA
HAFPRHYILKEGDLLKVDMVLSEPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAGRGLRLKEGMVLTVEPMINTGTW
EIDTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVILTSQAKKELIRMSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDL
SAIAVAYYLILTAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGGVLGIATLTGLWTMSRS
LASLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTFSKAAIQVLDRHYHLNDNITTLFLFLIQPITILI
IFIGLMLLYFLLPNIKIKKIRYILPGTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMVFIIMLWFIFLARILIMG
AVFNATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK

Sequences:

>Translated_599_residues
MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYVRRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVA
HAFPRHYILKEGDLLKVDMVLSEPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAGRGLRLKEGMVLTVEPMINTGTW
EIDTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVILTSQAKKELIRMSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDL
SAIAVAYYLILTAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGGVLGIATLTGLWTMSRS
LASLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTFSKAAIQVLDRHYHLNDNITTLFLFLIQPITILI
IFIGLMLLYFLLPNIKIKKIRYILPGTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMVFIIMLWFIFLARILIMG
AVFNATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK
>Mature_599_residues
MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYVRRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVA
HAFPRHYILKEGDLLKVDMVLSEPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAGRGLRLKEGMVLTVEPMINTGTW
EIDTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVILTSQAKKELIRMSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDL
SAIAVAYYLILTAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGGVLGIATLTGLWTMSRS
LASLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTFSKAAIQVLDRHYHLNDNITTLFLFLIQPITILI
IFIGLMLLYFLLPNIKIKKIRYILPGTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMVFIIMLWFIFLARILIMG
AVFNATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=280, Percent_Identity=28.5714285714286, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI40385867, Length=277, Percent_Identity=23.826714801444, Blast_Score=90, Evalue=5e-18,
Organism=Escherichia coli, GI1786364, Length=280, Percent_Identity=33.5714285714286, Blast_Score=144, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71996291, Length=249, Percent_Identity=28.1124497991968, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323273, Length=254, Percent_Identity=29.1338582677165, Blast_Score=113, Evalue=9e-26,
Organism=Drosophila melanogaster, GI21355531, Length=272, Percent_Identity=26.4705882352941, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24583427, Length=275, Percent_Identity=24.3636363636364, Blast_Score=92, Evalue=1e-18,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 67082; Mature: 67082

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYVRRRCKEDNVLPLQIGV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECC
DGQLMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLSEPLDKAVVDVAALDFDNV
CCCEECCCCHHHCCCCHHHHHHCCHHHHCCCCCEEEEHHHHHCCHHHHHHHHHHCCHHHH
AEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEAMYRGIEQAVVGNRIGDIGAA
HHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAGRGLRLKEGMVLTVEPMINTGTW
HHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCEEEEEECCCCCCCE
EIDTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVILTSQAKKELIRMSIKKFLDKVISK
EEECCCCCCCCCCCCCCCCCEEEECEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHH
WQYEPIQAFMRHFQSAEMDLSAIAVAYYLILTAFPLIVIAANIFPYLNIDISDLLRLMKE
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHH
QLPKDIYRSASSIVVNIFSKPSGGVLGIATLTGLWTMSRSLASLQKAFNKAYDASEHRDF
HCCHHHHHCHHHHEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LLGHLVGLLTSLLILFLLTFALIFSTFSKAAIQVLDRHYHLNDNITTLFLFLIQPITILI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IFIGLMLLYFLLPNIKIKKIRYILPGTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGS
HHHHHHHHHHHCCCCEEEHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMVFIIMLWFIFLARILIMGAVFNATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYVRRRCKEDNVLPLQIGV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECC
DGQLMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLSEPLDKAVVDVAALDFDNV
CCCEECCCCHHHCCCCHHHHHHCCHHHHCCCCCEEEEHHHHHCCHHHHHHHHHHCCHHHH
AEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEAMYRGIEQAVVGNRIGDIGAA
HHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAGRGLRLKEGMVLTVEPMINTGTW
HHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCEEEEEECCCCCCCE
EIDTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVILTSQAKKELIRMSIKKFLDKVISK
EEECCCCCCCCCCCCCCCCCEEEECEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHH
WQYEPIQAFMRHFQSAEMDLSAIAVAYYLILTAFPLIVIAANIFPYLNIDISDLLRLMKE
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHH
QLPKDIYRSASSIVVNIFSKPSGGVLGIATLTGLWTMSRSLASLQKAFNKAYDASEHRDF
HCCHHHHHCHHHHEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LLGHLVGLLTSLLILFLLTFALIFSTFSKAAIQVLDRHYHLNDNITTLFLFLIQPITILI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IFIGLMLLYFLLPNIKIKKIRYILPGTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGS
HHHHHHHHHHHCCCCEEEHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMVFIIMLWFIFLARILIMGAVFNATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]