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The map label for this gene is uxaC [H]

Identifier: 195977823

GI number: 195977823

Start: 714873

End: 716270

Strand: Direct

Name: uxaC [H]

Synonym: Sez_0689

Alternate gene names: 195977823

Gene position: 714873-716270 (Clockwise)

Preceding gene: 195977822

Following gene: 195977824

Centisome position: 35.32

GC content: 43.28

Gene sequence:

>1398_bases
ATGGCTTTTAATGACGACAATTTTATGCTAAAAAATGAGGCAGCAAAGCGCCTCTATCAACAAATCAAGGATCAGCCTAT
TTTTGATTACCATTGTCACTTAGATCCAAAGGAAATTTTTGAGGACAAGGTTTATGACAATATTGTTGACCTTTGGCTTG
GTGGTGATCACTACAAATGGCGTTTGATGCGTGCTAATGGCATTTCAGAAGAAGAAATCACAGGCTCAGCCTCTAAGCTG
GATAAATTCAAGGCCTTTGCCCGTACACTTCAGCGCTCCTATGGCAATCCTGTTTACCACTGGTCAGTAATGGAGTTGAA
AAATGTCTTTGGTGTCTGTGAGCTACTGACTGAGGATAATGCAGAGGAAATCTATCATCGTATCAATGCTTACTTGGTTG
AGCACCAGATTAGTCCTAGAAAGTTGATTGCAGATAGTCGGGTGCGGTTTATTGGTACGACCGATCACCCGCTTGATGAC
CTGGCTTGGCACAAGAGGTTAACTGCTGATGATACCTTTGAGACGGTTGTCGCGCCAACCTTTAGACCAGATGAAGCCTT
TATTGAGCATCAGCGCTTTGCAGATTTTGTGGCTCGTCTTGCTCAAGCTACAGGAAGAACTATTACAGATTTTAAGAGCT
TTATAGCGGCTATGGAAGAGCGTATTGCCTATTTTGCAGAAAATGGTTGTAAGGCCAGTGACATCAGCTTTACAGAGATT
GTCTTTGAAGCAGCAGAGCCAGAGCAATTAGACCGTCTCATGACAAGGGTTTTAGAGGGCTATCAGCCGCAGCCGTTAGA
GATCAAGCAATGGCAGACAGCGGTGTTTGCAGAGCTTTGCAGGCTTTATAAGCACTATGGCTTTGTTACTCAGGTGCATT
TTGGTGCTCTTCGCAATAATCATTCAGCTATTTTCAACAAACTAGGGGCAGATGTGGGTGTTGACTCACTGGGAGATCAA
GCAGCACTAGCTATCAATATGAACCGTTTGTTGGATCATCTGGTACAAAGAGACAGCCTGCCAAAGATGATCTGGTATAA
CCTAAATCCAAGCTATAATATTACAGTTCCCAATACACTTGCTAATTTCCAAGCCAATGAAAATGGTATTGCGGGCTATC
TGCAATTTGGTGCAGGCTGGTGGTTTGCTGATACCAAGCTTGGTATGATTAGCCAGATGAATGCCTTGGCTGAGCAAGGC
TTGTTAGCTAATTTTGTTGGCATGCTAACAGATTCACGTTCCTTTTTATCCTATCAGCGTCATGATTATTTCAGACGTAT
TTTGTCGACCTACCTTGGTGAGTGGATTGAAGAAGGTGAAGTACCAGAGGATTATCAGGTACTCGGCAGCATGGCCAAAG
ATATTGCCTACAATAACGCTATCCAGTATTTTAGCTAG

Upstream 100 bases:

>100_bases
CCGAGTTGAGGCTGAGGGCTATGACAGTGTGACTCGTATAGCAAGAGCATTTGTTTCAGCCCTTGATTGAGAAGTAGTAG
GTGTGTAAGAGGAGGACGAG

Downstream 100 bases:

>100_bases
GCTGTCTTGGTCGTTAGCTATAAGAAGCATAGAGATATGATGTTGCTCTATGGTCAAGATCCTGGTCTTAAAAGAGGCTA
GGACAATATCGACCTGCTGG

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKVYDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKL
DKFKAFARTLQRSYGNPVYHWSVMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDD
LAWHKRLTADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAMEERIAYFAENGCKASDISFTEI
VFEAAEPEQLDRLMTRVLEGYQPQPLEIKQWQTAVFAELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQ
AALAINMNRLLDHLVQRDSLPKMIWYNLNPSYNITVPNTLANFQANENGIAGYLQFGAGWWFADTKLGMISQMNALAEQG
LLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQVLGSMAKDIAYNNAIQYFS

Sequences:

>Translated_465_residues
MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKVYDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKL
DKFKAFARTLQRSYGNPVYHWSVMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDD
LAWHKRLTADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAMEERIAYFAENGCKASDISFTEI
VFEAAEPEQLDRLMTRVLEGYQPQPLEIKQWQTAVFAELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQ
AALAINMNRLLDHLVQRDSLPKMIWYNLNPSYNITVPNTLANFQANENGIAGYLQFGAGWWFADTKLGMISQMNALAEQG
LLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQVLGSMAKDIAYNNAIQYFS
>Mature_464_residues
AFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKVYDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLD
KFKAFARTLQRSYGNPVYHWSVMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDDL
AWHKRLTADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAMEERIAYFAENGCKASDISFTEIV
FEAAEPEQLDRLMTRVLEGYQPQPLEIKQWQTAVFAELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQA
ALAINMNRLLDHLVQRDSLPKMIWYNLNPSYNITVPNTLANFQANENGIAGYLQFGAGWWFADTKLGMISQMNALAEQGL
LANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQVLGSMAKDIAYNNAIQYFS

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=466, Percent_Identity=45.0643776824034, Blast_Score=415, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 53544; Mature: 53413

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKVYDNIVDLWLGGDHYKW
CCCCCCCCEEHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEE
RLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWSVMELKNVFGVCELLTEDN
EEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCC
AEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDDLAWHKRLTADDTFETVVAPT
HHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCHHHHCCCC
FRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAMEERIAYFAENGCKASDISFTEI
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
VFEAAEPEQLDRLMTRVLEGYQPQPLEIKQWQTAVFAELCRLYKHYGFVTQVHFGALRNN
HHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
HSAIFNKLGADVGVDSLGDQAALAINMNRLLDHLVQRDSLPKMIWYNLNPSYNITVPNTL
HHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCHH
ANFQANENGIAGYLQFGAGWWFADTKLGMISQMNALAEQGLLANFVGMLTDSRSFLSYQR
HCCCCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
HDYFRRILSTYLGEWIEEGEVPEDYQVLGSMAKDIAYNNAIQYFS
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKVYDNIVDLWLGGDHYKW
CCCCCCCEEHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEE
RLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWSVMELKNVFGVCELLTEDN
EEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCC
AEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDDLAWHKRLTADDTFETVVAPT
HHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCHHHHCCCC
FRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAMEERIAYFAENGCKASDISFTEI
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
VFEAAEPEQLDRLMTRVLEGYQPQPLEIKQWQTAVFAELCRLYKHYGFVTQVHFGALRNN
HHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
HSAIFNKLGADVGVDSLGDQAALAINMNRLLDHLVQRDSLPKMIWYNLNPSYNITVPNTL
HHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCHH
ANFQANENGIAGYLQFGAGWWFADTKLGMISQMNALAEQGLLANFVGMLTDSRSFLSYQR
HCCCCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
HDYFRRILSTYLGEWIEEGEVPEDYQVLGSMAKDIAYNNAIQYFS
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA