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The map label for this gene is murA [H]

Identifier: 195977816

GI number: 195977816

Start: 707165

End: 708424

Strand: Direct

Name: murA [H]

Synonym: Sez_0682

Alternate gene names: 195977816

Gene position: 707165-708424 (Clockwise)

Preceding gene: 195977815

Following gene: 195977817

Centisome position: 34.94

GC content: 46.03

Gene sequence:

>1260_bases
ATGCGAAAAATTATTATTAATGGTGGAAAAGCCTTATCCGGAGAGGTGGCAGTTTCAGGTGCTAAAAATAGCGTTGTAGC
GCTTATTCCTGCGATTATTTTGGCAGATGGTGTTGTCACTTTAGATGGGGTACCAGCTATTAGTGATGTTGACAGCCTTA
TCGAAATCATGAAGCTCATGGGAGCTATGGTGACCTATCAGGGGGATACCTTGGAGATTGACCCCAGAGGGGTTCAAAAT
ATTCCTATGCCTTATGGTAAAATTAACAGCCTAAGAGCCTCTTACTATTTTTATGGTAGTCTATTGGGACGCTTTGGGCA
GGCGGTTGTGGGCTTGCCGGGTGGCTGTGACTTGGGCCCTAGGCCTATTGATCTCCACCTGAAGGCTTTTGAAGCAATGG
GGGCCCAGATATCTTATGAGGGAGCAAGCATGCACCTGATGACAGAGGCTCAGCAGCTTCATGGCGCTCATATCTACATG
GATACTGTCAGTGTAGGCGCTACCATTAATACCATGATTGCTGCAACAAAGGCAAAGGGTAAGACCATTATTGAAAATGC
AGCTAGAGAGCCTGAGATTATTGACGTTGCGACACTGTTAAATAACATGGGGGCGCATATTCGTGGTGCAGGTACTGATG
TGATTACGATTGAGGGAGTTGAAAGGCTTCATGGTACCAGGCATCAGGTGATCCCAGATCGTATTGAGGCCGGTACCTAT
ATTGCCTTAGCGGCCGCTATTGGTAGTGGGGTAAGGATTACCAATGTCCTTTACGAGCACTTAGAGAGCTTTATTGCTAA
GCTGGAGGAAATGGGTGTGAGAATGACGGTTGAAGAGGATTCTATTTTTGTGGAAAAGCAGGAAGCCTTGAAAGCAGTCA
CTATTAAAACCTCTCCCTATCCAGGCTTTGCCACTGACCTACAGCAGCCTTTGACTCCTCTGCTTTTAAGGGCTGAGGGT
CGTGGTAGTATCATTGATACGATATATGAAAAGCGTGTCAATCATGTGCCAGAGCTTGCTCGTATGGGAGCAGATATTGC
CATTCTTGGCAGCCAAATTGTTTATCATGGCTCTAATCAGCTCAGTGGGGCACAGGTTAAGGCAACTGATTTGCGGGCTG
GTGCTGCTTTGGTGATTGCAGGCCTAATGGCTCAGGGTAAAACCGAGATTAGCAATATTGAGTTTATTTTACGTGGCTAC
GCTAACATTATTGATAAGCTAACAGCCTTAGGGGCTGACATTCAGCTTATTGAGGCTTAA

Upstream 100 bases:

>100_bases
TTAAGCCTGTTGCAGCAGCTGGTGATGAGGTGATTGTAATAGACCGCTATTTGTGATAAAATAAAAAGGTTGAATTCTAG
TATCAGAAAGTTTTGAAAGT

Downstream 100 bases:

>100_bases
GAACTGAAGGCTTTTATAGCCTAATGAGTATCACCTGACATGAATGCTTAGAGCTCCTAAGACTGCTTGGTATGAGAGTG
GTTTTAGGGGCTTTTGGTTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADGVVTLDGVPAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQN
IPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
DTVSVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIEGVERLHGTRHQVIPDRIEAGTY
IALAAAIGSGVRITNVLYEHLESFIAKLEEMGVRMTVEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRAEG
RGSIIDTIYEKRVNHVPELARMGADIAILGSQIVYHGSNQLSGAQVKATDLRAGAALVIAGLMAQGKTEISNIEFILRGY
ANIIDKLTALGADIQLIEA

Sequences:

>Translated_419_residues
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADGVVTLDGVPAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQN
IPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
DTVSVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIEGVERLHGTRHQVIPDRIEAGTY
IALAAAIGSGVRITNVLYEHLESFIAKLEEMGVRMTVEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRAEG
RGSIIDTIYEKRVNHVPELARMGADIAILGSQIVYHGSNQLSGAQVKATDLRAGAALVIAGLMAQGKTEISNIEFILRGY
ANIIDKLTALGADIQLIEA
>Mature_419_residues
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADGVVTLDGVPAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQN
IPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
DTVSVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIEGVERLHGTRHQVIPDRIEAGTY
IALAAAIGSGVRITNVLYEHLESFIAKLEEMGVRMTVEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRAEG
RGSIIDTIYEKRVNHVPELARMGADIAILGSQIVYHGSNQLSGAQVKATDLRAGAALVIAGLMAQGKTEISNIEFILRGY
ANIIDKLTALGADIQLIEA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=47.1428571428571, Blast_Score=356, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44606; Mature: 44606

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADGVVTLDGVPAISDVDSLIEIMKLM
CCEEEEECCCEECCCEEECCCCCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHH
GAMVTYQGDTLEIDPRGVQNIPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGP
HHHEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCC
RPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYMDTVSVGATINTMIAATKAKG
CCEEEEEHHHHHCCCEEEECCCEEEEEHHHHHHCCCEEEEEEEECCCCHHHHEEECCCCC
KTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIEGVERLHGTRHQVIPDRIEAGTY
CHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEECCHHHHCCCCCCCCCHHHCCCCC
IALAAAIGSGVRITNVLYEHLESFIAKLEEMGVRMTVEEDSIFVEKQEALKAVTIKTSPY
EEEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEHHHCCEEEEEECCCC
PGFATDLQQPLTPLLLRAEGRGSIIDTIYEKRVNHVPELARMGADIAILGSQIVYHGSNQ
CCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHCCCCEEEECCEEEEECCCC
LSGAQVKATDLRAGAALVIAGLMAQGKTEISNIEFILRGYANIIDKLTALGADIQLIEA
CCCCEEEEHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADGVVTLDGVPAISDVDSLIEIMKLM
CCEEEEECCCEECCCEEECCCCCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHH
GAMVTYQGDTLEIDPRGVQNIPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGP
HHHEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCC
RPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYMDTVSVGATINTMIAATKAKG
CCEEEEEHHHHHCCCEEEECCCEEEEEHHHHHHCCCEEEEEEEECCCCHHHHEEECCCCC
KTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIEGVERLHGTRHQVIPDRIEAGTY
CHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEECCHHHHCCCCCCCCCHHHCCCCC
IALAAAIGSGVRITNVLYEHLESFIAKLEEMGVRMTVEEDSIFVEKQEALKAVTIKTSPY
EEEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEHHHCCEEEEEECCCC
PGFATDLQQPLTPLLLRAEGRGSIIDTIYEKRVNHVPELARMGADIAILGSQIVYHGSNQ
CCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHCCCCEEEECCEEEEECCCC
LSGAQVKATDLRAGAALVIAGLMAQGKTEISNIEFILRGYANIIDKLTALGADIQLIEA
CCCCEEEEHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]