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The map label for this gene is pepF [H]

Identifier: 195977795

GI number: 195977795

Start: 683684

End: 685486

Strand: Direct

Name: pepF [H]

Synonym: Sez_0661

Alternate gene names: 195977795

Gene position: 683684-685486 (Clockwise)

Preceding gene: 195977794

Following gene: 195977796

Centisome position: 33.78

GC content: 43.48

Gene sequence:

>1803_bases
ATGACAGATAATCGTAGTCATCTAGAGGAAAAGTACACTTGGGATTTAAGCACTATTTTTGCAACTGACGCAGCTTGGGA
GACAGAAGCAGATAGCCTGTCAGCAGCTATTGAGGCTGCAAGACAGCAGGCTGGGCATTTGTTGGATTCAAGCAGCAGTC
TCTTAGATATCACAGAGCTGCAGTTGGAGCTGGCTCGTCGTGTTGAAAAGCTTTATGTTTATGCCAGCATGAAAAACGAT
CAGGATACAACAGTTGCCAAGTATCAGGAATATCAGGCAAAGGCTTCTGGTATTTATGCTAAATTTAGCGAAGCCTTTTC
TTTTTATGAGCCAGAGTTTATGGCCTTGAGTCAAGAGACCTATCAGGCCTTCTTAGCGGAGAAGCCAGAATTAGCAGTCT
ATGACCATTTCTTTGATAAATTGTTCAAGGCGCGTGAGCATGTCCTTAGTCAGGCTGAGGAGGAGCTATTAGCAGGGGCA
CAAGAAATCTTTAATGGTGCTGAGGAGACCTTTAGTATCCTCGATAATGCCGATATTGCTTTTCCTATTGTGACAAATGA
TAAGGGAGAAGAGGTTGAGCTAACACATGGTAATTTCATTAGCTTGATGGAATCTAAAGACCGCAAGGTGCGTAGGGCGG
CCTATGAGGCGATGTACAGCACCTATGAGCAATTCCAGCATACCTACGCTAAAACCCTGCAAACCAATGTCAAGGTGCAA
AATTATAAGGCACGTGTCCATAAGTATGCTTCAGCCCGTCAGGCAGCGATGTCAGCCAACTTTATCCCAGAGGCTGTTTA
CGATACCCTACTAGAAACCGTTAATAAGCATTTGCCGCTGCTTCATCGTTATTTGAAGCTACGTCAAGAGGTGCTTGGTT
TAGATGATCTAAAGATGTATGATGTTTATACTCCTTTATCTGAGACAGATCTTGCTATCGGCTATGATGAGGCCTTGGAA
AAAGCAGAGAAGGTTTTGGCTGTTTTTGGCCAGGATTATTCAGAGCGTGTGCATCGTGCCTTTACAGAGCGTTGGATTGA
TGTGCATGTCAATAAGGGCAAACGCTCAGGAGCTTACTCTGGTGGTTCCTATGATACCAATGCCTTTATGCTCTTAAATT
GGCAGGACACGCTTGATAACCTCTATACGCTAGTGCATGAGACAGGCCATAGCCTGCACTCAACCTTTACGCGTGAAACA
CAGCCTTACGTGTATGGAGATTACAGCATTTTCTTAGCTGAGATTGCTTCAACCACTAATGAAAATATCATGACTGAGGC
CTTGTTACATGAGGTGCAGGATGATAAGGAGCGCTTTGCTATTTTGAATCATTACCTAGATGGTTTTCGCGGAACGGTTT
TTCGTCAGACACAGTTTGCTGAGTTTGAGCACGCTATTCATCAGGCAGATCAAAATGGCGAGGTGTTAACAAGTGAATAC
CTCAATAAGCTATATGCTGATTTAAATGAAAAGTATTATGGATTAAAGAAAGAGGACAACCACTTTATCCAGTATGAGTG
GGCTCGTATTCCACACTTCTATTACAACTACTATGTCTATCAATATGCAACAGGCTTTGCTGCAGCCAGCTACTTGGCTG
ATAAGATTGTGCATGGTACTCAAGAGGATATTGATCACTACTTGACTTATCTGAAGTCTGGAAATTCAGATTATCCTCTT
GAGGTGATTGCCAAGGCTGGTGTTGATATGGCTAAGGGGGATTACCTAGAAGCAGCCTTTAAGGTCTTTGAAGAGCGCTT
GACAGAGCTAGAGGACTTAGTGGCAAGAGGGGCACATCTTTAA

Upstream 100 bases:

>100_bases
GAAAAATATTACGCAAAAGCAGCAAATAAAGAGGTGCAAAAGCTTTTTTCACCAGCATATTATGTTAAAATGATTAATAA
CAGAAACTTAGGAGGTCCGT

Downstream 100 bases:

>100_bases
CCATTGTTGTCTATAGCTAAATAGGCATAATTGCAAAGGCTTATTTGTTAAAACAGCCTATGAGCAGCCCCTAGAAATGG
TGTGCCATTAGTGAGCTAGG

Product: oligoendopeptidase PepF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 600; Mature: 599

Protein sequence:

>600_residues
MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLSAAIEAARQQAGHLLDSSSSLLDITELQLELARRVEKLYVYASMKND
QDTTVAKYQEYQAKASGIYAKFSEAFSFYEPEFMALSQETYQAFLAEKPELAVYDHFFDKLFKAREHVLSQAEEELLAGA
QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
NYKARVHKYASARQAAMSANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALE
KAEKVLAVFGQDYSERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRET
QPYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSEY
LNKLYADLNEKYYGLKKEDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPL
EVIAKAGVDMAKGDYLEAAFKVFEERLTELEDLVARGAHL

Sequences:

>Translated_600_residues
MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLSAAIEAARQQAGHLLDSSSSLLDITELQLELARRVEKLYVYASMKND
QDTTVAKYQEYQAKASGIYAKFSEAFSFYEPEFMALSQETYQAFLAEKPELAVYDHFFDKLFKAREHVLSQAEEELLAGA
QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
NYKARVHKYASARQAAMSANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALE
KAEKVLAVFGQDYSERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRET
QPYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSEY
LNKLYADLNEKYYGLKKEDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPL
EVIAKAGVDMAKGDYLEAAFKVFEERLTELEDLVARGAHL
>Mature_599_residues
TDNRSHLEEKYTWDLSTIFATDAAWETEADSLSAAIEAARQQAGHLLDSSSSLLDITELQLELARRVEKLYVYASMKNDQ
DTTVAKYQEYQAKASGIYAKFSEAFSFYEPEFMALSQETYQAFLAEKPELAVYDHFFDKLFKAREHVLSQAEEELLAGAQ
EIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAMYSTYEQFQHTYAKTLQTNVKVQN
YKARVHKYASARQAAMSANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEK
AEKVLAVFGQDYSERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRETQ
PYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSEYL
NKLYADLNEKYYGLKKEDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPLE
VIAKAGVDMAKGDYLEAAFKVFEERLTELEDLVARGAHL

Specific function: Has oligopeptidase activity and degrades a variety of small bioactive peptides, including bradykinin, neurotensin, and peptide fragments of substance P and adrenocorticotropin. Also hydrolyzes the synthetic collagen-like substrate N-(3-[2- furyl]acryloyl)

COG id: COG1164

COG function: function code E; Oligoendopeptidase F

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567
- InterPro:   IPR004438
- InterPro:   IPR013647 [H]

Pfam domain/function: PF01432 Peptidase_M3; PF08439 Peptidase_M3_N [H]

EC number: NA

Molecular weight: Translated: 69066; Mature: 68935

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLSAAIEAARQQAGHLLDSSSSLLDITEL
CCCCHHHHHHHHCCCHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
QLELARRVEKLYVYASMKNDQDTTVAKYQEYQAKASGIYAKFSEAFSFYEPEFMALSQET
HHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
YQAFLAEKPELAVYDHFFDKLFKAREHVLSQAEEELLAGAQEIFNGAEETFSILDNADIA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEE
FPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
EEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
NYKARVHKYASARQAAMSANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMY
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
DVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYSERVHRAFTERWIDVHVNKGKRSGAYS
EEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCCCCCC
GGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRETQPYVYGDYSIFLAEIASTTN
CCCCCCCEEEEEECHHHHHHHHHHHHHHCHHHHHHHHCCCCCEEECCHHHHHHHHHHCCC
ENIMTEALLHEVQDDKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSEY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LNKLYADLNEKYYGLKKEDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGT
HHHHHHHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QEDIDHYLTYLKSGNSDYPLEVIAKAGVDMAKGDYLEAAFKVFEERLTELEDLVARGAHL
HHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDNRSHLEEKYTWDLSTIFATDAAWETEADSLSAAIEAARQQAGHLLDSSSSLLDITEL
CCCHHHHHHHHCCCHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
QLELARRVEKLYVYASMKNDQDTTVAKYQEYQAKASGIYAKFSEAFSFYEPEFMALSQET
HHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
YQAFLAEKPELAVYDHFFDKLFKAREHVLSQAEEELLAGAQEIFNGAEETFSILDNADIA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEE
FPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
EEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
NYKARVHKYASARQAAMSANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMY
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
DVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYSERVHRAFTERWIDVHVNKGKRSGAYS
EEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCCCCCC
GGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRETQPYVYGDYSIFLAEIASTTN
CCCCCCCEEEEEECHHHHHHHHHHHHHHCHHHHHHHHCCCCCEEECCHHHHHHHHHHCCC
ENIMTEALLHEVQDDKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSEY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LNKLYADLNEKYYGLKKEDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGT
HHHHHHHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QEDIDHYLTYLKSGNSDYPLEVIAKAGVDMAKGDYLEAAFKVFEERLTELEDLVARGAHL
HHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8757883; 12354221 [H]