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The map label for this gene is lytR [H]

Identifier: 195977570

GI number: 195977570

Start: 455255

End: 456517

Strand: Direct

Name: lytR [H]

Synonym: Sez_0429

Alternate gene names: 195977570

Gene position: 455255-456517 (Clockwise)

Preceding gene: 195977569

Following gene: 195977575

Centisome position: 22.49

GC content: 44.02

Gene sequence:

>1263_bases
ATGAAAATTGGAAAAAAAATCTTTTTAATGCTGACAGCTATTGTGCTGTTGACCTTGGGGGCTATGGGAGTTTACCTAAC
CAATGCCTATACCTTTTCAACTGGAGAATTGTCAAAGACCTTTAAGGATTTTGCAACGTCCTCCAAAAAAAGTGATGCCA
TTCAACAGACAGAGCCCTTTTCAATTCTATTGATGGGAGTTGACACCGGATCGTCTCACAGAACCTCTACCTGGCAGGGC
AATAGTGATTCTATGATCCTGGTTACGATTAACCCTAAGACCAAAAAGACAACCATGACAAGCTTAGAAAGAGACATTCT
CATCACTTTGTCAGGTCCAAATGATAATGAGATGAATGGAGCAGAAGCTAAGCTGAATGCTGCTTATGCAGCTGGTGGTG
CGCAGATGGCTATCATGACGGTTCAGGACTTGCTGAATATCACGATTGACAAATACGTTCAGATTAACATGCAGGGACTC
ATTGATCTGGTTAATGCTGTTGGTGGCATTACTGTTACCAATGAATTTGACTTTCCTATTTCTATTGCAGACAATGAGCC
TGAGTATCAGGCTACCGTCGCGCCGGGAACTCACAAGATAAATGGAGAGCAGGCCTTGGTATATGCTAGAATGCGCTATG
ATGATCCAGAGGGAGACTATGGTCGTCAGAAGCGTCAGCGAGAGGTCATTCAAAAGGTGCTGAAAAAGATTCTTGCCCTT
AATAGTATCAGCTCCTACCGAAAGATCTTGTCAGCTGTTAGTGGTAATATGCAAACCAACATTGAAATATCATCACGAAC
CATTCCTAATCTTTTAGGCTATACAGACGCTCTCAAAAATATCAAGACCTATCAGCTTAAGGGTGAGGGAGCGACCTTGT
CAGACGGCGGCTCCTATCAAATTGTGACCTCAGACCATCTCTTAGAAATTCAAAATAGGATTCGTGCTGAATTAGGGCTA
GAAAAGCTTAGTCAGCTAAAAACGACTGCCACAGTTTACGAAAACCTTTATGGCTCGTTAAAGACTCAGTCTACTCAGGA
TAGCAGCTATTATTACAATTCAGGCAGCCTGCCAGCCTATACAGACTCATCTACCCAGTACTCAACCTATTCCTCAGAGA
CGTCCTCTAGTAGCACCTATCAGGACACAACAGCTGGTACACAAGAGTCAGGAGCAGCTAATGTGACTCCTAGCCCTCAA
GCAGACTCACCAGCAGAGCAGCAATCAAGCGGTACAACCACTGGTACACCAGCAGCGCCTTAG

Upstream 100 bases:

>100_bases
TGGCTTTAAAATAGAGGGCGTCAAAAGAAAGGACGTCAAATCAAGAAATGGAGACTATCAGGATGTTTACCTTATGCGTA
AATATCTGGAACGTGAATAG

Downstream 100 bases:

>100_bases
GGCACAGCCAAAAAAACGAAGAAATCTTATCAGGGCTTGATCCTGTGAGTGATTTCTTCGTTTTTTGCACATATAAAAAA
GAGTCCTATCCTTCCTATAG

Product: transcriptional regulator LytR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDFATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQG
NSDSMILVTINPKTKKTTMTSLERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEGDYGRQKRQREVIQKVLKKILAL
NSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTDALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGL
EKLSQLKTTATVYENLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSTYQDTTAGTQESGAANVTPSPQ
ADSPAEQQSSGTTTGTPAAP

Sequences:

>Translated_420_residues
MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDFATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQG
NSDSMILVTINPKTKKTTMTSLERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEGDYGRQKRQREVIQKVLKKILAL
NSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTDALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGL
EKLSQLKTTATVYENLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSTYQDTTAGTQESGAANVTPSPQ
ADSPAEQQSSGTTTGTPAAP
>Mature_420_residues
MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDFATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQG
NSDSMILVTINPKTKKTTMTSLERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEGDYGRQKRQREVIQKVLKKILAL
NSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTDALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGL
EKLSQLKTTATVYENLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSTYQDTTAGTQESGAANVTPSPQ
ADSPAEQQSSGTTTGTPAAP

Specific function: Involved in biofilm formation, cell division, autolysis and the regulation of acid and oxidative stress tolerance. May be associated with systemic virulence in blood [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell envelope (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 45452; Mature: 45452

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDFATSSKKSDAIQQTEPF
CCCCHHHHHHHHHHHHHHHHHHHEEEECEEEECCCHHHHHHHHHHCCCCCCCCHHCCCCE
SILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSLERDILITLSGPNDNEMNG
EEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCEEEEEEECCCCCCCCC
AEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGLIDLVNAVGGITVTNEFDFPI
CHHHEEHHEECCCCEEEHHHHHHHHHHCCHHEEEEEHHHHHHHHHHHCCEEEEECCCCEE
SIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEGDYGRQKRQREVIQKVLKKILAL
EECCCCCCEEEEECCCCEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
NSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTDALKNIKTYQLKGEGATLSDGGSYQ
HHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCEECCCCCEE
IVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYENLYGSLKTQSTQDSSYYYNSGSLPAY
EEECHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCC
TDSSTQYSTYSSETSSSSTYQDTTAGTQESGAANVTPSPQADSPAEQQSSGTTTGTPAAP
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDFATSSKKSDAIQQTEPF
CCCCHHHHHHHHHHHHHHHHHHHEEEECEEEECCCHHHHHHHHHHCCCCCCCCHHCCCCE
SILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSLERDILITLSGPNDNEMNG
EEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCEEEEEEECCCCCCCCC
AEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGLIDLVNAVGGITVTNEFDFPI
CHHHEEHHEECCCCEEEHHHHHHHHHHCCHHEEEEEHHHHHHHHHHHCCEEEEECCCCEE
SIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEGDYGRQKRQREVIQKVLKKILAL
EECCCCCCEEEEECCCCEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
NSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTDALKNIKTYQLKGEGATLSDGGSYQ
HHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCEECCCCCEE
IVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYENLYGSLKTQSTQDSSYYYNSGSLPAY
EEECHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCC
TDSSTQYSTYSSETSSSSTYQDTTAGTQESGAANVTPSPQADSPAEQQSSGTTTGTPAAP
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]