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The map label for this gene is secA [H]

Identifier: 195977512

GI number: 195977512

Start: 388422

End: 390950

Strand: Direct

Name: secA [H]

Synonym: Sez_0367

Alternate gene names: 195977512

Gene position: 388422-390950 (Clockwise)

Preceding gene: 195977511

Following gene: 195977513

Centisome position: 19.19

GC content: 44.6

Gene sequence:

>2529_bases
ATGAGCAATATTCTACGCAAAGTCATTGAAAATGATAAAGGCGAATTACGAAAATTAGAAAAAATTGCGAAAAAAGTAGA
GTCCTATGCTGACTATATGGAGTCCTTGTCAGATAAAGACCTACAAGCAAAAACGCCCGAATTTAAACAACGTTATCAAA
ATGGGGAAACCCTTGAGCAGTTATTACCAGAAGCATTTGCGGTTGTCCGCGAGGCGGCTAGACGTGTGCTGGGACTTTAC
CCTTATCGTGTTCAGATCATGGGGGGAATTGTCTTGCACAATGGAGATGTTCCTGAGATGCGTACCGGTGAAGGTAAGAC
CCTTACAGCGACCATGCCTGTTTACCTTAATGCCCTTGCTGGCAAAGGGGTACACGTTATCACTGTTAACGAATACCTGT
CAACTCGTGACGCAACAGAGATGGGAGAGGTTTATAGCTGGCTAGGACTTTCAGTCGGTATCAACCTAGCAGCTAAATCA
CCAGCTGAAAAGCGTGAGGCTTATCTATGTGACATTACCTACTCAACCAACTCTGAGGTGGGCTTTGACTACCTGCGTGA
TAACATGGTGGTTCGTCAAGAGGACATGGTTCAACGACCATTGAACTTTGCCTTGGTCGATGAGGTTGACTCTGTTTTGA
TTGACGAGGCAAGAACGCCTCTGATTGTCTCTGGTGCTGTGAGCTCAGAAACGAATCAGCTCTATATTCGTGCAGACATG
TTTGTCAAAACCTTGGATTCAGTTGATTACATCATTGATGTTCCGACCAAGACGATTGGCCTAAGCGACTCAGGTATTGA
TAAGGCAGAAAGCTATTTCAACCTCAGCAACCTATACGATATTGAAAATGTTGCCTTGACCCACTTCGTGGATAATGCCC
TTCGTGCTAACTATATCATGCTTTTAGATATTGATTACGTGGTTAGCGAGGAAGGTGAGATTTTGATTGTAGACCAGTTT
ACAGGTCGTACAATGGAAGGACGACGCTTTTCAGATGGCTTGCACCAAGCTATTGAGGCGAAAGAAGGCGTTCGTATTCA
AGAGGAATCAAAAACAAGTGCCTCTATTACCTACCAAAACATGTTCCGTATGTATAAGAAATTGGCGGGTATGACTGGTA
CAGCAAAAACAGAGGAAGAGGAATTCCGCGAGGTTTACAACATGCGTATTATTCCGATTCCAACCAATCGTCCTATTGCT
CGTATTGATCACACAGACCTTCTTTATGCAACGTTGAATTCAAAATTCAAGGCAGTGGTTGCAGATGTTAAGGCTCGCTA
TGAAAAGGGGCAGCCCGTTCTAGTTGGTACAGTTGCTGTTGAAACCAGTGACCTTATCTCTAAAAAGCTAGTAGAGGCAG
GCATTCCGCATGAGGTCTTAAATGCTAAGAACCACTTTAAAGAAGCACAGATCATTATGAATGCTGGTCAGCGTGGTGCA
GTAACGATTGCGACCAATATGGCTGGTCGTGGGACAGACATTAAGCTTGGTGAGGGTGTTCGAGAGCTCGGTGGGCTTTG
TGTTATCGGGACAGAGCGTCATGAGAGCCGCCGTATTGATAATCAGCTTCGTGGGCGTTCAGGTCGTCAGGGAGATCCAG
GGGAATCACAATTCTACCTCTCCTTAGAGGACGAGCTGATGAGGCGCTTTGGTACAGACCGTATTAAGGCCTTCTTGGAT
CGTATGAACCATGATGACGAGGATATTGTTATCAAGTCCAGAATGTTGTCACGTCAGGTGGAGTCAGCTCAAAAACGTGT
TGAGGGTAATAACTATGACACACGTAAGCAGGTCTTACAGTATGATGATGTGATGCGTGAGCAGCGTGAGATTATCTATG
CTAACCGTCGTGATGTTATCACAGCAAATCGTGATCTAGGTCCTGAAATTAAGGCAATGATCAAGCGTACGATTGATCGA
GCAGTTGATGCCCACTCACGTACCAATCGTAAGGACGCCATTGATGCCATTGTGACCTTTGCAAGAACATCAATTGTCCC
AGAGGAAACCATCGGTGCTAAGGAATTGCGTGGCCTCAAGGACGATCAGATCAAAGACAAGCTCTATCAGCGTGCCCTTG
AGATTTATGATAAGCAGTTATCAAAATTGCGCGATCAGGACGCTATCTTAGAATTCCAGAAGGTGCTGATTTTGATGATT
GTTGACAACAAATGGACAGAGCATATTGATGCCTTAGACCAGCTTCGTAATGCGGTTGGTTTGCGTGGTTATGCGCAAAA
TAATCCAGTTGTTGAATATCAAAGTGAAGGCTTCAAGATGTTCCAGGATATGATTGGTGCTATCGAATTTGATGTTACAC
GTACCATGATGAAGGCACAGATTCATGAGCAGGAGCGCGAGCGTGCAACTCAGTATGCAACAACAACTGCAGCACAAAAC
ATTCAGTCGCAGGCTATCGGTGCTGATTTTGATTCATCAGCTGATTTTTCAAGAGTCGAGCGCAATGATGCTTGTCCTTG
TCACTCTGGTAAGAAGTTTAAAAACTGTCATGGTCGTAAGGCTTTTTAA

Upstream 100 bases:

>100_bases
TTTTCTTCATGTGTCTGTCGTGGATATCTTATGATCATTTCTTGAACTGCCTGCCTATTTATGTTAGAATAAAATGATTA
GTCGATCGAAAGGAAAGAGA

Downstream 100 bases:

>100_bases
GGATGGCGTGATGGCCATGTTGAAAACCTGTGAGAAGCTGAGATTTGTTCTCGGCTTCTCCTTGTTTAGGATTTGTTTCC
CTAAATTAAAGTGAAGGCTG

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 842; Mature: 841

Protein sequence:

>842_residues
MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAKTPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLY
PYRVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNALAGKGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRADM
FVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLSNLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQF
TGRTMEGRRFSDGLHQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIA
RIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKLVEAGIPHEVLNAKNHFKEAQIIMNAGQRGA
VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLD
RMNHDDEDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIDR
AVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDDQIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMI
VDNKWTEHIDALDQLRNAVGLRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERATQYATTTAAQN
IQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF

Sequences:

>Translated_842_residues
MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAKTPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLY
PYRVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNALAGKGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRADM
FVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLSNLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQF
TGRTMEGRRFSDGLHQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIA
RIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKLVEAGIPHEVLNAKNHFKEAQIIMNAGQRGA
VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLD
RMNHDDEDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIDR
AVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDDQIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMI
VDNKWTEHIDALDQLRNAVGLRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERATQYATTTAAQN
IQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF
>Mature_841_residues
SNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAKTPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYP
YRVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNALAGKGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKSP
AEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRADMF
VKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLSNLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFT
GRTMEGRRFSDGLHQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIAR
IDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKLVEAGIPHEVLNAKNHFKEAQIIMNAGQRGAV
TIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDR
MNHDDEDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIDRA
VDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDDQIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIV
DNKWTEHIDALDQLRNAVGLRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERATQYATTTAAQNI
QSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family [H]

Homologues:

Organism=Escherichia coli, GI1786287, Length=894, Percent_Identity=44.407158836689, Blast_Score=722, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116 [H]

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]

EC number: NA

Molecular weight: Translated: 95309; Mature: 95177

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00200 RIESKE_2 ; PS01312 SECA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAKTPEFKQRYQNGETLEQ
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHH
LLPEAFAVVREAARRVLGLYPYRVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNALA
HHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCCCCCCCCCCEEEEEHHHHHHHHC
GKGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKSPAEKREAYLCDITYSTNSEV
CCCEEEEEEHHHHHHCCHHHHHHHHHHHHHHHCCEEECCCCHHHCCEEEEEEEECCCCCC
GFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRADM
CHHHHHCCCEECHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEHHH
FVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLSNLYDIENVALTHFVDNALRANYIM
HHHHHHCCCEEEECCCCEECCCCCCCHHHHHHHCHHHHCCHHHHHHHHHHHHHHHCCEEE
LLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGLHQAIEAKEGVRIQEESKTSASITYQN
EEEEEHEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHH
MFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIARIDHTDLLYATLNSKFKAVV
HHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCEEECCCHHHHHHHCCHHHHHH
ADVKARYEKGQPVLVGTVAVETSDLISKKLVEAGIPHEVLNAKNHFKEAQIIMNAGQRGA
HHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCE
VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYL
EEEEECCCCCCCCEECCCCHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEE
SLEDELMRRFGTDRIKAFLDRMNHDDEDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQ
EHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
YDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTF
HHHHHHHHHHHEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ARTSIVPEETIGAKELRGLKDDQIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMI
HHHCCCCHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEE
VDNKWTEHIDALDQLRNAVGLRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQ
ECCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
IHEQERERATQYATTTAAQNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCHHHCCCCCC
AF
CC
>Mature Secondary Structure 
SNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAKTPEFKQRYQNGETLEQ
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHH
LLPEAFAVVREAARRVLGLYPYRVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNALA
HHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCCCCCCCCCCEEEEEHHHHHHHHC
GKGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKSPAEKREAYLCDITYSTNSEV
CCCEEEEEEHHHHHHCCHHHHHHHHHHHHHHHCCEEECCCCHHHCCEEEEEEEECCCCCC
GFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRADM
CHHHHHCCCEECHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEHHH
FVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLSNLYDIENVALTHFVDNALRANYIM
HHHHHHCCCEEEECCCCEECCCCCCCHHHHHHHCHHHHCCHHHHHHHHHHHHHHHCCEEE
LLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGLHQAIEAKEGVRIQEESKTSASITYQN
EEEEEHEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHH
MFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIARIDHTDLLYATLNSKFKAVV
HHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCEEECCCHHHHHHHCCHHHHHH
ADVKARYEKGQPVLVGTVAVETSDLISKKLVEAGIPHEVLNAKNHFKEAQIIMNAGQRGA
HHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCE
VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYL
EEEEECCCCCCCCEECCCCHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEE
SLEDELMRRFGTDRIKAFLDRMNHDDEDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQ
EHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
YDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTF
HHHHHHHHHHHEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ARTSIVPEETIGAKELRGLKDDQIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMI
HHHCCCCHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEE
VDNKWTEHIDALDQLRNAVGLRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQ
ECCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
IHEQERERATQYATTTAAQNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCHHHCCCCCC
AF
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA