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The map label for this gene is ptsG [H]

Identifier: 195977389

GI number: 195977389

Start: 264527

End: 266038

Strand: Direct

Name: ptsG [H]

Synonym: Sez_0242

Alternate gene names: 195977389

Gene position: 264527-266038 (Clockwise)

Preceding gene: 195977388

Following gene: 195977390

Centisome position: 13.07

GC content: 42.2

Gene sequence:

>1512_bases
ATGGATTTTAAGAAATTTTCAAAATTAGGTCAGGCCTTTATGCTGCCGATCTCAATCTTACCAGTTGCTGGTTTGTTGTT
GGGGATTGGTGGGGCCCTGTCAAATAGCAATGCCATTGCACAATTTCCGATATTAAATCAAGCATGGCTACAGGCTATTT
TTACCATTATGAGCACAGCAGGTAACGCTGTTTTTGCTAATATTGCCTTGATTTTTGCGATTGGTGTTGCTGTTGGCTTA
GCCAACGGAGATAAAGGAACAGCCGGTCTTTCAGGTGCTGTGGCTTATTTGGTCTTTACGGCAACCATTAGCGGCTATCT
GACTCTTTTTTCAGCAAAGGACGCTCAGATTGATACGGGTGTTTTAGGGGCTTTGACGGTTGGCTTAGTTGTTGTTAGCC
TTCACAATAAGTACCGAAAGATCGAACTGCCAGCCTTTTTAGGCTTCTTTGGCGGCTCTCGTTTTATTCCGATTGTTTCC
TCATTGGCAGCGATTGTGATTGGTAGTGTTTTCTATGTCATTTGGCCACCTATTCAAAATCTCCTAGTAGTGTTTGGTGA
AAAAATTGCGGATATGGGAAGCATTGGAACATTCTTGTACGGTTTCTTTTTACGTTTGACAGGAGCAGTAGGACTGCACC
ACACCATTTACCCAATGTTTTGGTATACATCACTTGGCGGTAGTGAGGTTGTAGCAGGTGAGACTATCCAAGGAGCACAA
AATATTTTCTTTGCGCAATTGGCTGACGCTAATCATACTGGCTTGTTTACTTACGGGACACGCTTTTTTGCAGGACGTTT
TGCAACTATGATGTTTGGACTACCTGCTGCCTGTCTTGCTATGTATCACGCTATTCCAAAGGCTAATCGTAAAAAGGTTG
GTAGCTTTTATTCAAGTAGTGCCTTGACTTCCTTACTAACAGGGATCACAGAGCCTATTGAGTTTGCCTTTTTATTCGTA
GCACCTTGGCTCTACGTGGTTCACGCTTTCTTAGATGGCTGTTCTTTCTTAGTTGCTGATTTATTAAAGATTCGTATCGG
TAATTCCTTCTCAGGTGGTCTGATTGACTTTTTAATCTTTGGTGTGTTCCAAGGAAATGATCATACCAACTGGCTACTTG
TTATCCCTGTTGGTATCGTGTGGTTTATGGTTTATTACTTTGTCTTTAAATTCTTTGTGAGCAAATTCCAGGTTGCTGTA
CCGGGAATGGTAGCTCAGGTAGAAGCAGAAGGACAGGCAGAGACTACTAGTGCTCAAGGCTCATCACTTCGTGAGGCGTC
ATTAGCTATTATTGAAGCCTTGGGAGGACCAGCTAATATCGAAGATGTAACCGCTTGCGCGACTCGCTTGAGAGTTTCTC
TGTCAGATAGTAGCTTGGTCAACAAGAATGTCTTAACCTCACTGGGAGCAACAGCTGTATTAGATGTTAAAAATGGCATT
CAGGCTATTTATGGTGGTAAGGCTATCCTTTATAGTCAAGAAATCAATCAACTATTAGGTAGAGAAGATTAA

Upstream 100 bases:

>100_bases
GCCTTGGGAGTCGCTGGTATTGTGGTTGGTGGTGCTATTACCAGACCAAAGGAAATTGCAGAGCGCTTTGTGGTGGCTCT
CAAGAAGGAGGAGTAATCAA

Downstream 100 bases:

>100_bases
CATGATAAAGAAGTGGAAGCAATTATTATCAGCAAAAAAAGCTGATGCGTTAAGCGATCGTATTTTATCAGTGGCTAAGG
GACAATTAGTTCCTATTACC

Product: PTS system glucose-specific EIICBA component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPILNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGL
ANGDKGTAGLSGAVAYLVFTATISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYPMFWYTSLGGSEVVAGETIQGAQ
NIFFAQLADANHTGLFTYGTRFFAGRFATMMFGLPAACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFV
APWLYVVHAFLDGCSFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFFVSKFQVAV
PGMVAQVEAEGQAETTSAQGSSLREASLAIIEALGGPANIEDVTACATRLRVSLSDSSLVNKNVLTSLGATAVLDVKNGI
QAIYGGKAILYSQEINQLLGRED

Sequences:

>Translated_503_residues
MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPILNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGL
ANGDKGTAGLSGAVAYLVFTATISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYPMFWYTSLGGSEVVAGETIQGAQ
NIFFAQLADANHTGLFTYGTRFFAGRFATMMFGLPAACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFV
APWLYVVHAFLDGCSFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFFVSKFQVAV
PGMVAQVEAEGQAETTSAQGSSLREASLAIIEALGGPANIEDVTACATRLRVSLSDSSLVNKNVLTSLGATAVLDVKNGI
QAIYGGKAILYSQEINQLLGRED
>Mature_503_residues
MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPILNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGL
ANGDKGTAGLSGAVAYLVFTATISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYPMFWYTSLGGSEVVAGETIQGAQ
NIFFAQLADANHTGLFTYGTRFFAGRFATMMFGLPAACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFV
APWLYVVHAFLDGCSFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFFVSKFQVAV
PGMVAQVEAEGQAETTSAQGSSLREASLAIIEALGGPANIEDVTACATRLRVSLSDSSLVNKNVLTSLGATAVLDVKNGI
QAIYGGKAILYSQEINQLLGRED

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=514, Percent_Identity=37.5486381322957, Blast_Score=330, Evalue=1e-91,
Organism=Escherichia coli, GI1787343, Length=506, Percent_Identity=39.5256916996047, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1786894, Length=497, Percent_Identity=37.625754527163, Blast_Score=267, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 53642; Mature: 53642

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPILNQAWLQAIFTIMSTA
CCHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHC
GNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTATISGYLTLFSAKDAQIDTG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCH
VLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVSSLAAIVIGSVFYVIWPPIQN
HHHHHHHHHHHHHHHHCHHEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
LLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYPMFWYTSLGGSEVVAGETIQGAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHH
NIFFAQLADANHTGLFTYGTRFFAGRFATMMFGLPAACLAMYHAIPKANRKKVGSFYSSS
HHHHHEECCCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHH
ALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGCSFLVADLLKIRIGNSFSGGLIDFLIF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFFVSKFQVAVPGMVAQVEAEGQAETTSAQG
HHEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
SSLREASLAIIEALGGPANIEDVTACATRLRVSLSDSSLVNKNVLTSLGATAVLDVKNGI
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEECCCHHHHHHHHHHCCCCEEEEHHHCH
QAIYGGKAILYSQEINQLLGRED
HHHHCCCEEEEHHHHHHHHCCCC
>Mature Secondary Structure
MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPILNQAWLQAIFTIMSTA
CCHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHC
GNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTATISGYLTLFSAKDAQIDTG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCH
VLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVSSLAAIVIGSVFYVIWPPIQN
HHHHHHHHHHHHHHHHCHHEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
LLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYPMFWYTSLGGSEVVAGETIQGAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHH
NIFFAQLADANHTGLFTYGTRFFAGRFATMMFGLPAACLAMYHAIPKANRKKVGSFYSSS
HHHHHEECCCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHH
ALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGCSFLVADLLKIRIGNSFSGGLIDFLIF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFFVSKFQVAVPGMVAQVEAEGQAETTSAQG
HHEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
SSLREASLAIIEALGGPANIEDVTACATRLRVSLSDSSLVNKNVLTSLGATAVLDVKNGI
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEECCCHHHHHHHHHHCCCCEEEEHHHCH
QAIYGGKAILYSQEINQLLGRED
HHHHCCCEEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]