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The map label for this gene is fhuC [H]

Identifier: 195977379

GI number: 195977379

Start: 256836

End: 257543

Strand: Direct

Name: fhuC [H]

Synonym: Sez_0232

Alternate gene names: 195977379

Gene position: 256836-257543 (Clockwise)

Preceding gene: 195977378

Following gene: 195977380

Centisome position: 12.69

GC content: 37.57

Gene sequence:

>708_bases
ATGCTTGAAGTCAAAAGCCTGTGTAAATCATTTGGCAGTCATTGTGTTTTGGATCATTTATCAATCACACTTGGAACAAG
AGGGATTACTGTTATTGTTGGCTTGAACGGTTCGGGAAAGACTGTTTTTCTAGATTCGGTAGCAGGAATAATCCAGTATG
ACAAAGGAAATGTCTCACTAGATGGGCATGCGAGTGGCAGTGATGCTTTTAAAACAAATAGCTTTTATATCCCATCAGAT
TCTTATCTGCCAGAATATCTAACCGGTCGTGAATATGCGGCATTTATCCAATCACGCTACGCTAATGCTAATGGCTCTGT
ATTTGTTGAGCTTTCCCGTCTTTTGGATATGACTGAGGCATTAGATAGACCAATAGAAGCTTATTCATTTGGTATGAAAA
AGAAGCTTCAAATTGCTCTGGGGCTTTCTTTGAATGTGGGATATCTTCTTGCAGATGAGGCATTTAGTGGATTAGATTTG
GAAACGGTCATTCTTATTCAGGAATTGTTTAGTCTTTATGCCAGAGAGCATAAGCTTTTGCTTGTTTCTCATGAGCGACA
TATTATCAATCAATTTTCGACTGATATTTTATTAATGGAGAAAGGGAAACTAACTGAGTTTAGAGGTACAGCAGATGAGC
TTTCTGACTATATTTATCAAAAAGGAAGGATTACTGAGAAGCTTCAAAGAATTGCAGAAATCCTTTGA

Upstream 100 bases:

>100_bases
TGAGCTAGTTTCTAGAGAGTCTGTAGTTTATTCGCTTTTCGCTTTTAATAGCCCATCATGTCCTATTCTCAGACAGCAGA
TTATTATCTTAGGAGGTCGT

Downstream 100 bases:

>100_bases
GTTAGTGTCTTTTTATTATAACGACGCTTTAAATGGCTTTTTAAATAGGCCTTTTTTTAAGAAAAAGAAAAATCAGTACC
TTGTAGCGATTGTTGGCTTT

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MLEVKSLCKSFGSHCVLDHLSITLGTRGITVIVGLNGSGKTVFLDSVAGIIQYDKGNVSLDGHASGSDAFKTNSFYIPSD
SYLPEYLTGREYAAFIQSRYANANGSVFVELSRLLDMTEALDRPIEAYSFGMKKKLQIALGLSLNVGYLLADEAFSGLDL
ETVILIQELFSLYAREHKLLLVSHERHIINQFSTDILLMEKGKLTEFRGTADELSDYIYQKGRITEKLQRIAEIL

Sequences:

>Translated_235_residues
MLEVKSLCKSFGSHCVLDHLSITLGTRGITVIVGLNGSGKTVFLDSVAGIIQYDKGNVSLDGHASGSDAFKTNSFYIPSD
SYLPEYLTGREYAAFIQSRYANANGSVFVELSRLLDMTEALDRPIEAYSFGMKKKLQIALGLSLNVGYLLADEAFSGLDL
ETVILIQELFSLYAREHKLLLVSHERHIINQFSTDILLMEKGKLTEFRGTADELSDYIYQKGRITEKLQRIAEIL
>Mature_235_residues
MLEVKSLCKSFGSHCVLDHLSITLGTRGITVIVGLNGSGKTVFLDSVAGIIQYDKGNVSLDGHASGSDAFKTNSFYIPSD
SYLPEYLTGREYAAFIQSRYANANGSVFVELSRLLDMTEALDRPIEAYSFGMKKKLQIALGLSLNVGYLLADEAFSGLDL
ETVILIQELFSLYAREHKLLLVSHERHIINQFSTDILLMEKGKLTEFRGTADELSDYIYQKGRITEKLQRIAEIL

Specific function: Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system [H]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI145693107, Length=231, Percent_Identity=26.8398268398268, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787041, Length=221, Percent_Identity=23.9819004524887, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787029, Length=216, Percent_Identity=24.537037037037, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.34 [H]

Molecular weight: Translated: 26116; Mature: 26116

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEVKSLCKSFGSHCVLDHLSITLGTRGITVIVGLNGSGKTVFLDSVAGIIQYDKGNVSL
CCCHHHHHHHHCCCEEEHHHEEEECCCCEEEEEEECCCCCEEEEECCCCCEEECCCCEEE
DGHASGSDAFKTNSFYIPSDSYLPEYLTGREYAAFIQSRYANANGSVFVELSRLLDMTEA
CCCCCCCCCCCCCCEECCCCCCCCHHHCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHH
LDRPIEAYSFGMKKKLQIALGLSLNVGYLLADEAFSGLDLETVILIQELFSLYAREHKLL
HCCCHHHHHCCCCEEEEEEEECEECCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEE
LVSHERHIINQFSTDILLMEKGKLTEFRGTADELSDYIYQKGRITEKLQRIAEIL
EEECHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHC
>Mature Secondary Structure
MLEVKSLCKSFGSHCVLDHLSITLGTRGITVIVGLNGSGKTVFLDSVAGIIQYDKGNVSL
CCCHHHHHHHHCCCEEEHHHEEEECCCCEEEEEEECCCCCEEEEECCCCCEEECCCCEEE
DGHASGSDAFKTNSFYIPSDSYLPEYLTGREYAAFIQSRYANANGSVFVELSRLLDMTEA
CCCCCCCCCCCCCCEECCCCCCCCHHHCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHH
LDRPIEAYSFGMKKKLQIALGLSLNVGYLLADEAFSGLDLETVILIQELFSLYAREHKLL
HCCCHHHHHCCCCEEEEEEEECEECCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEE
LVSHERHIINQFSTDILLMEKGKLTEFRGTADELSDYIYQKGRITEKLQRIAEIL
EEECHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]