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The map label for this gene is gluP [H]

Identifier: 195977362

GI number: 195977362

Start: 237576

End: 238259

Strand: Direct

Name: gluP [H]

Synonym: Sez_0215

Alternate gene names: 195977362

Gene position: 237576-238259 (Clockwise)

Preceding gene: 195977361

Following gene: 195977366

Centisome position: 11.74

GC content: 46.64

Gene sequence:

>684_bases
ATGAGACTGATGATCAAAAAATACCCGATAACACTCTTTTTCTTGGGCTTGACTGGTTTAGTTTTTTTGATAATGCAGCT
GGTCTATGGCCAGTTTGCTACGCACCCTTATGCTGTTGTTATATTTGGTGGCATGAATGGTCTTGTTGTCAGAGCAATGC
CTGGTCAGCTTTGGCGCTTGGTGACACCGATAGTGGTTCATATTGGCTTTGGGCATTTTTTCATTAATGCTTTAACCCTT
TATTTTGTCGGGCGGCTGGCTGAGTCCATTTGGGGCTCAAGACAGTTTTTGCTGCTGTATGTGTGTTCGGGGATTATGGG
GAATGCCTTTATCATGTGGCTGACACCAGATATCGTAGCAGCAGGCGCTTCCACCTCTCTTTTTGGTCTTTTTGCGGCGA
TTGCTGTCTTAGGAATAGGAGGAAACAACCATTCCTTGAGAGAGCTAGGCAGGTCCTATCAGGCCTTGATTGTGATGAAC
TTATTGCTCAATCTGTTTATGCCTAATGTGAGTATTGCTGGTCACCTAGGAGGTGTTGTTGGTGGCGGGCTATGCGGTGT
TGCCTTGTCCAATCAGCTGCCAGATCAAGCCTTTTCGAGCCGGCAAAGAAGGCTGGCAGCCTTGGCTTATGTCGTGATTG
TGGTAGGCATAGTAAGCCGTAGCTTTCTGTCCTTAGCTAGTTAG

Upstream 100 bases:

>100_bases
GGGATTATCAGGGGGCTACCTTTAGCACGATTTATGCCTGTCAGTGGGAGGATTTTGTGGTAGAGGCACATGATATTGCT
GTGAAGGAGGTGTATTGCCA

Downstream 100 bases:

>100_bases
CAGGAGCTCTCGGTGATAGCTGGTTGCTAGGGCTCCTTGCTTGTTAGGGCATAGTCGCTGTAGCAGTGCTGCTGTGAGCT
CTAAGCTCTGCCATCTGGAG

Product: membrane protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MRLMIKKYPITLFFLGLTGLVFLIMQLVYGQFATHPYAVVIFGGMNGLVVRAMPGQLWRLVTPIVVHIGFGHFFINALTL
YFVGRLAESIWGSRQFLLLYVCSGIMGNAFIMWLTPDIVAAGASTSLFGLFAAIAVLGIGGNNHSLRELGRSYQALIVMN
LLLNLFMPNVSIAGHLGGVVGGGLCGVALSNQLPDQAFSSRQRRLAALAYVVIVVGIVSRSFLSLAS

Sequences:

>Translated_227_residues
MRLMIKKYPITLFFLGLTGLVFLIMQLVYGQFATHPYAVVIFGGMNGLVVRAMPGQLWRLVTPIVVHIGFGHFFINALTL
YFVGRLAESIWGSRQFLLLYVCSGIMGNAFIMWLTPDIVAAGASTSLFGLFAAIAVLGIGGNNHSLRELGRSYQALIVMN
LLLNLFMPNVSIAGHLGGVVGGGLCGVALSNQLPDQAFSSRQRRLAALAYVVIVVGIVSRSFLSLAS
>Mature_227_residues
MRLMIKKYPITLFFLGLTGLVFLIMQLVYGQFATHPYAVVIFGGMNGLVVRAMPGQLWRLVTPIVVHIGFGHFFINALTL
YFVGRLAESIWGSRQFLLLYVCSGIMGNAFIMWLTPDIVAAGASTSLFGLFAAIAVLGIGGNNHSLRELGRSYQALIVMN
LLLNLFMPNVSIAGHLGGVVGGGLCGVALSNQLPDQAFSSRQRRLAALAYVVIVVGIVSRSFLSLAS

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 24482; Mature: 24482

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLMIKKYPITLFFLGLTGLVFLIMQLVYGQFATHPYAVVIFGGMNGLVVRAMPGQLWRL
CCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCHHHHHH
VTPIVVHIGFGHFFINALTLYFVGRLAESIWGSRQFLLLYVCSGIMGNAFIMWLTPDIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEECHHHHH
AGASTSLFGLFAAIAVLGIGGNNHSLRELGRSYQALIVMNLLLNLFMPNVSIAGHLGGVV
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GGGLCGVALSNQLPDQAFSSRQRRLAALAYVVIVVGIVSRSFLSLAS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLMIKKYPITLFFLGLTGLVFLIMQLVYGQFATHPYAVVIFGGMNGLVVRAMPGQLWRL
CCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCHHHHHH
VTPIVVHIGFGHFFINALTLYFVGRLAESIWGSRQFLLLYVCSGIMGNAFIMWLTPDIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEECHHHHH
AGASTSLFGLFAAIAVLGIGGNNHSLRELGRSYQALIVMNLLLNLFMPNVSIAGHLGGVV
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GGGLCGVALSNQLPDQAFSSRQRRLAALAYVVIVVGIVSRSFLSLAS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]