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The map label for this gene is ulaD [H]

Identifier: 195977318

GI number: 195977318

Start: 185121

End: 185783

Strand: Direct

Name: ulaD [H]

Synonym: Sez_0171

Alternate gene names: 195977318

Gene position: 185121-185783 (Clockwise)

Preceding gene: 195977317

Following gene: 195977319

Centisome position: 9.15

GC content: 49.77

Gene sequence:

>663_bases
ATGACACATATTCCAAAATTACAGGTTGCCTTAGATCATTCTGATTTGCAAGGGGCGGTTAGGGCTGCTGTTGCAGTTGG
TCACGAGGTTGATGTGATCGAAGCAGGGACAGTTTGCCTGCTTCAAGTAGGCAGCGAATTGGTTGAGGTGCTGCGTAGCT
TATTTCCAGAGAAGATCATCGTAGCAGACACCAAGTGTGCAGACGCTGGCGGTACTGTTGCTAAGAATAATGCTAAGCGT
GGTGCGGACTGGATGACCTGTATTTGCTGTGCTACGATTCCAACGATGGCAGCAGCACTGAAAGCCATCAAAGAAGAGCG
TGGGGATCGTGGCGAGATTCAGGTTGAGCTGTATGGTGATTGGACCTATGAGCAGGCACAATTGTGGCTAGATGCAGGCA
TTTCACAGGCGATTTACCATCAATCACGTGACGCCCTACTTGCTGGTGAGGTGTGGGGTGAAAAAGACCTGAACAAGGTC
AAAGCCCTCATTGACATGGGCTTTCGTGTGTCGGTGACGGGTGGCTTAGATATCAATACCCTCAAGCTCTTTGAAGGGGT
TGATGTCTTTACCTTTATTGCAGGTCGTGGTATCACTGAAGCAGAGGATCCTGCAGCAGCGGCACGTGCCTTTAAAGACG
AGATTCGACGCATTTGGGGGTAA

Upstream 100 bases:

>100_bases
TAAACAAGCCATCATCACTAGATAAATCAAACATAACAGAAAGGGTAGGAGCTCACTACTAAGCATTGAAGGCGGTGCTA
CGGGCTCTTGGTAAAAAATC

Downstream 100 bases:

>100_bases
CAATATGGCGCGTCCTATTGGTATATATGAAAAAGCAACGCCAAAGCATTTTACTTGGCTGGAACGCTTGCAATTTGCAA
AGGCATTAGGCTTTGATTTT

Product: 3-keto-L-gulonate-6-phosphate decarboxylase

Products: NA

Alternate protein names: 3-dehydro-L-gulonate-6-phosphate decarboxylase; KGPDC; L-ascorbate utilization protein D [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQVGSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKR
GADWMTCICCATIPTMAAALKAIKEERGDRGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNKV
KALIDMGFRVSVTGGLDINTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIRRIWG

Sequences:

>Translated_220_residues
MTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQVGSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKR
GADWMTCICCATIPTMAAALKAIKEERGDRGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNKV
KALIDMGFRVSVTGGLDINTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIRRIWG
>Mature_219_residues
THIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQVGSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRG
ADWMTCICCATIPTMAAALKAIKEERGDRGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNKVK
ALIDMGFRVSVTGGLDINTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIRRIWG

Specific function: Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization [H]

COG id: COG0269

COG function: function code G; 3-hexulose-6-phosphate synthase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. KGPDC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790640, Length=217, Percent_Identity=48.3870967741936, Blast_Score=207, Evalue=6e-55,
Organism=Escherichia coli, GI1790006, Length=216, Percent_Identity=46.2962962962963, Blast_Score=181, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.85 [H]

Molecular weight: Translated: 23797; Mature: 23666

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQVGSELVEVLRSLFPEKII
CCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEE
VADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALKAIKEERGDRGEIQVELYGD
EECCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
WTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNKVKALIDMGFRVSVTGGLDINT
CCHHHHHHHHHHCHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCHH
LKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIRRIWG
HHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
THIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQVGSELVEVLRSLFPEKII
CCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEE
VADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALKAIKEERGDRGEIQVELYGD
EECCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
WTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNKVKALIDMGFRVSVTGGLDINT
CCHHHHHHHHHHCHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCHH
LKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIRRIWG
HHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA