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The map label for this gene is comGA [H]

Identifier: 195977266

GI number: 195977266

Start: 128366

End: 129304

Strand: Direct

Name: comGA [H]

Synonym: Sez_0115

Alternate gene names: 195977266

Gene position: 128366-129304 (Clockwise)

Preceding gene: 195977265

Following gene: 195977267

Centisome position: 6.34

GC content: 44.09

Gene sequence:

>939_bases
ATGGTTCAAGAATTAGCCAAGAGGCTTATCAGGCAGGCCGAAGAATTGCAGGCTCAGGATATTTATATACTGCCAAGAGG
GGCAGGCTATGAGCTTTTGATGAGGATAGGTGATGACAGGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGAATGTGGGAGAAAAAAGACGCTGCCAGCTCGGTGCTTGTGACTACGAC
CTTGATGGCACTAAGGTATCTCTACGATTATCAGCTGTGGGTGACTATCAGGGACAGGAGAGCTTGGTTATTCGTCTCTT
GTATCATCATCAACGCCAGCTCAGGTATTGGTTTGATGGTTTAGAGCGAGTCACATCAGCTATTGGAGCCAGAGGCCTTT
ACCTCTTTTCTGGACCGGTTGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATAAAAAATGACCAGCTCCTGCAATTACAGGTTAACGACAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTCTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATTAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTGACAGGAGCAATGGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGTGTTTAC
GCTAGGCTGTTAGAATTAGGCATTTCTAGGGCAGAATTGGATAATAGTCTAGCAATGGTTGCTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCGCAAAAGGAATTTGAACATCATCAAGCCAGCCAGTGGAATCAGAAGATTGATCAGC
TTCTTGCAGAGGGACATCTCAATACCAAGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Upstream 100 bases:

>100_bases
GCTGAATTCCTTACTTGATGTTAAACATTTATCAAAAAAATGGCCTTTTTCTTGAGGCTATTTTTTTTATTTTTCGAATA
GTCTTAGTGAGGAGGTAAGA

Downstream 100 bases:

>100_bases
GCAGCAGGAAAAGCTTATCCAATTGCTCTATAACCTATTGTCTAATGGCTTTAATTTGACAGAGGTCATTGCTTTTTTGA
GAAAAAGCCAGCTGCTACTG

Product: late competence protein ComGA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MVQELAKRLIRQAEELQAQDIYILPRGAGYELLMRIGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDGTKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQASQWNQKIDQLLAEGHLNTKQARLEKIIQ

Sequences:

>Translated_312_residues
MVQELAKRLIRQAEELQAQDIYILPRGAGYELLMRIGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDGTKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQASQWNQKIDQLLAEGHLNTKQARLEKIIQ
>Mature_312_residues
MVQELAKRLIRQAEELQAQDIYILPRGAGYELLMRIGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDGTKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQASQWNQKIDQLLAEGHLNTKQARLEKIIQ

Specific function: Required for uptake of DNA by competent cells [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1786296, Length=271, Percent_Identity=34.3173431734317, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789723, Length=271, Percent_Identity=32.8413284132841, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI87082188, Length=165, Percent_Identity=32.7272727272727, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 35227; Mature: 35227

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQELAKRLIRQAEELQAQDIYILPRGAGYELLMRIGDDRRLIDVCESDRMANLISHFKF
CHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHEEECCCCHHHHHHCCHHHHHHHHHHHH
VAGMNVGEKRRCQLGACDYDLDGTKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFDG
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQVISIEDPVEIKNDQLLQLQV
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEE
NDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
CCCCCCCHHHHHEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQASQWNQKIDQLLAEGHL
HHHHHHCCCHHHHCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NTKQARLEKIIQ
CHHHHHHHHHCC
>Mature Secondary Structure
MVQELAKRLIRQAEELQAQDIYILPRGAGYELLMRIGDDRRLIDVCESDRMANLISHFKF
CHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHEEECCCCHHHHHHCCHHHHHHHHHHHH
VAGMNVGEKRRCQLGACDYDLDGTKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFDG
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQVISIEDPVEIKNDQLLQLQV
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEE
NDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
CCCCCCCHHHHHEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQASQWNQKIDQLLAEGHL
HHHHHHCCCHHHHCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NTKQARLEKIIQ
CHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2507524; 8969508; 9384377; 9422590; 9723928 [H]