Click here to switch to the map view.

The map label for this gene is hisZ [H]

Identifier: 195952814

GI number: 195952814

Start: 381329

End: 382177

Strand: Direct

Name: hisZ [H]

Synonym: HY04AAS1_0436

Alternate gene names: 195952814

Gene position: 381329-382177 (Clockwise)

Preceding gene: 195952811

Following gene: 195952817

Centisome position: 24.45

GC content: 29.56

Gene sequence:

>849_bases
GTGAATGGTTTTTTAGATTTAAAAGCTTCAAAAGTGTTTAAACAATTTATAGTGTTTGCAGAAGAGATATTAAGTGAAAA
AGGATATAGTTTTATAAAGCTTCCAATGTTTGATAGCTTTTATAATCAAATGAGAACCACCACCAACTACAATGAACTTA
TCACCATAAGGTCTTCAAAAGAGGTGTTTGTTTTAAGAAAAGACATGACTTATCAAGTGGCAAGCTATATAGCCTCTTTG
AAAGAAAGAGCTTTACCTATAAGGATATATTATGAAGGTGAAGTGTTTTCTTGGGAAAATGAAATAAAATCCGATTATCA
GCTTGGTTTAGAATACATAGGATACGATAAAGACGATGGGATATTTGAAGTAATTGATATTATATATAAGCTTTTAGCAT
TTTTTAACAACGATATTTTCATTTATATAAACGATGAAGCTATACTAAAGGAGCTTCTGTCAAAGTTTGATGATAAACAT
AAAGAAGATGTAAAATACGCTCTTACATCAAAAAATCTAAATACACTTTATAAATATGACCTTGATTGGATGCTTTTGGA
AGATGAAAATGTACTTTTTGAAAAACTCAATGCTTTGAACATTGATGGTGTTAGGCTCCGGAATGTTTTTTATATTTTAA
AAAATAAGTCTTTAAACGTAAGGCTTGATATATCAGAGTTAAAATCTATCCCTTACTACGATGGTATAACGTTTTCTTTC
TATTCGCCAAACCATCCTTTTGCAATAGCCTCTGGTGGTGAATATCAGATTTTAAAAAACGTTTATAATTTAGACATAAA
AGCTTGCGGTGGTGCTATATATCTTTCTTCCATATTGGAGAAAATATAA

Upstream 100 bases:

>100_bases
TATACCTTTGTTTGCTAAAAAATAAGCCGCTTCTGAACCAGCAAGCCCTGCTCCTATGACGTTTACTTTCATGTTAATAT
TTTATGATAAAATAGTTGCT

Downstream 100 bases:

>100_bases
TTACCTAGATATTGGTACGGTTAGATGCTCTAAGTTAAATACGTTAAAAGTCAAAAGAACATAATTTATATATTGATTTC
TTGTACCATCAAAGTACTCT

Product: ATP phosphoribosyltransferase regulatory subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNGFLDLKASKVFKQFIVFAEEILSEKGYSFIKLPMFDSFYNQMRTTTNYNELITIRSSKEVFVLRKDMTYQVASYIASL
KERALPIRIYYEGEVFSWENEIKSDYQLGLEYIGYDKDDGIFEVIDIIYKLLAFFNNDIFIYINDEAILKELLSKFDDKH
KEDVKYALTSKNLNTLYKYDLDWMLLEDENVLFEKLNALNIDGVRLRNVFYILKNKSLNVRLDISELKSIPYYDGITFSF
YSPNHPFAIASGGEYQILKNVYNLDIKACGGAIYLSSILEKI

Sequences:

>Translated_282_residues
MNGFLDLKASKVFKQFIVFAEEILSEKGYSFIKLPMFDSFYNQMRTTTNYNELITIRSSKEVFVLRKDMTYQVASYIASL
KERALPIRIYYEGEVFSWENEIKSDYQLGLEYIGYDKDDGIFEVIDIIYKLLAFFNNDIFIYINDEAILKELLSKFDDKH
KEDVKYALTSKNLNTLYKYDLDWMLLEDENVLFEKLNALNIDGVRLRNVFYILKNKSLNVRLDISELKSIPYYDGITFSF
YSPNHPFAIASGGEYQILKNVYNLDIKACGGAIYLSSILEKI
>Mature_282_residues
MNGFLDLKASKVFKQFIVFAEEILSEKGYSFIKLPMFDSFYNQMRTTTNYNELITIRSSKEVFVLRKDMTYQVASYIASL
KERALPIRIYYEGEVFSWENEIKSDYQLGLEYIGYDKDDGIFEVIDIIYKLLAFFNNDIFIYINDEAILKELLSKFDDKH
KEDVKYALTSKNLNTLYKYDLDWMLLEDENVLFEKLNALNIDGVRLRNVFYILKNKSLNVRLDISELKSIPYYDGITFSF
YSPNHPFAIASGGEYQILKNVYNLDIKACGGAIYLSSILEKI

Specific function: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine [H]

COG id: COG3705

COG function: function code E; ATP phosphoribosyltransferase involved in histidine biosynthesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004517
- InterPro:   IPR004516 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 33035; Mature: 33035

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGFLDLKASKVFKQFIVFAEEILSEKGYSFIKLPMFDSFYNQMRTTTNYNELITIRSSK
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCCEEEEEECCC
EVFVLRKDMTYQVASYIASLKERALPIRIYYEGEVFSWENEIKSDYQLGLEYIGYDKDDG
EEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCEEECHHHHHHHHHHCHHHCCCCCCCC
IFEVIDIIYKLLAFFNNDIFIYINDEAILKELLSKFDDKHKEDVKYALTSKNLNTLYKYD
HHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCHHHHHEEEECCCCCEEEEEC
LDWMLLEDENVLFEKLNALNIDGVRLRNVFYILKNKSLNVRLDISELKSIPYYDGITFSF
CCEEEECCCCHHHHHHCCCCCCCEEEEEEEEEEECCCEEEEEEHHHHCCCCCCCCEEEEE
YSPNHPFAIASGGEYQILKNVYNLDIKACGGAIYLSSILEKI
ECCCCCEEEECCCCHHHHHHHHCCCHHHCCCHHHHHHHHHHC
>Mature Secondary Structure
MNGFLDLKASKVFKQFIVFAEEILSEKGYSFIKLPMFDSFYNQMRTTTNYNELITIRSSK
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCCEEEEEECCC
EVFVLRKDMTYQVASYIASLKERALPIRIYYEGEVFSWENEIKSDYQLGLEYIGYDKDDG
EEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCEEECHHHHHHHHHHCHHHCCCCCCCC
IFEVIDIIYKLLAFFNNDIFIYINDEAILKELLSKFDDKHKEDVKYALTSKNLNTLYKYD
HHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCHHHHHEEEECCCCCEEEEEC
LDWMLLEDENVLFEKLNALNIDGVRLRNVFYILKNKSLNVRLDISELKSIPYYDGITFSF
CCEEEECCCCHHHHHHCCCCCCCEEEEEEEEEEECCCEEEEEEHHHHCCCCCCCCEEEEE
YSPNHPFAIASGGEYQILKNVYNLDIKACGGAIYLSSILEKI
ECCCCCEEEECCCCHHHHHHHHCCCHHHCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]