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The map label for this gene is rpoC

Identifier: 195952637

GI number: 195952637

Start: 231585

End: 236276

Strand: Direct

Name: rpoC

Synonym: HY04AAS1_0259

Alternate gene names: 195952637

Gene position: 231585-236276 (Clockwise)

Preceding gene: 195952636

Following gene: 195952638

Centisome position: 14.85

GC content: 36.7

Gene sequence:

>4692_bases
ATGAAGAGAGGTTTGTTACCTTTTAATAAGATAAAGCTTTTGCTTGCCTCACCAGAGCAAATACTTAGTTGGAGTCATGG
AGAGGTTAAGCGTCCTGAGACTTTAAATTACCGCACTCTGAAACCCGAAAAGGAAGGTCTTTTCTGTGCAAAAATATTTG
GACCTTTGAAAGATTACGAATGTTTGTGTGGAAAATATAAAGGTAAGAGATTTGAAGGTACTATTTGTGATAGATGCGGT
GTTGAAGTAACGAAAGCTTACGTTAGAAGAGAACGATTTGGCCATATAACCCTTGCTACTCCTTGTGCTCATATATGGTT
TTTAAAATCTTCTCCGTCTAAGATAGGTGCATTGCTTGGTTTGTCCGCTAGAGATATAGAAAAGGTTATATATTTTGAGT
CTTACTTAGTGGTAGAATATCCAACTCCTGACATGGAGGCTACTTTCTCAAATTCAGAAAATACTATCCCTGTTATAAAA
GATGGTGTTACTCATCATGTAAAACTGCACGTTGTTACGGAAGAACAATATGAGAAGGAGTTTGCTTACAGTATAGACAA
CAGGTACGAAAGTGGGATGGGAGCCGAATTTGTAAGATATGTTTTATCTATTTTAGACTTAGAAACGTTTGCTTTTAAAC
TAAAGAAAATTTTGAAGCCTTACACCTTTGGATTTGAAGATTTGGGTCCAAAGATGGAGCTAGAGCATAAAAAGCTTTAC
GAAAAGATAATAATGTTTTTAGCAGACAGGGTAAAGCTTTACAGCGTAGGTATCGCTACATCGCTTAACGGTGTTCAGAT
GTCTATTGAAGACGTGATTCATGGTATTGTAAGTGAGTCAATATATTTAAACATCAAAACTGGTGAAATATCCAATCAGG
ATTTAGGGGACGATTGGTATACTTCAAAAGATGCTATAAGGTACAGATTTGAATATGTAAGAGGACAAAATCAAAATATC
CCTGTTTTTGATAAGATACAAGAAGATGTTAGAAATATAGTTTTAAAGGACTTCTCGGATACAAGGGTTAAAAATTTAGT
AAAAACCTTAAAACTTGTAGAAGGCTTTTTGAAATCTTCCAATAGACCAGAATGGATGATATTAACAGTTTTACCGGTAA
TACCTCCAGAGTTAAGACCACTGGTAGCTTTAGATGGGGGCAAGTTTGCTACATCTGATTTAAACGATCTTTACAGAAGG
CTTATAAATAGAAACAATCGCTTGAAAAGGCTTATAGACTTGGATGCCCCAGATATCATAGTGAGAAATGAAAAGAGGAT
GCTCCAAGAATCAGTGGATGTTCTTATAGACAACGGCAAGAGAGGCAAGGTAGTAAGCCAACACAATAGACCGCTTAAAA
GCTTATCAGATTATCTCAAAGGAAAGCAAGGCAGGTTTAGACAAAACCTTTTGGGTAAGAGGGTCGATTACTCTGGTCGT
TCTGTCATAGTGGTAGGCCCTTCTTTAAAGATGCACCAGTGCGGTTTGCCAAAGATAATGGCTTTAGAGTTGTTCAAACC
TTTTGTTTATAGAAGACTTGAGGAAAAAGGTTATGCCACTTCTATAAAAAATGCTAGGAAGATGGTAGATCAAAAACAGC
CAGAAGTATGGGAATGTTTAGAGGAAGTTGTCAAGCAACATCCAGTATTGCTAAACAGAGCTCCTACACTTCACAGGATG
TCTATTCAAGCCTTTGAGCCTGTTTTGGTGGAAGGCAAGGCAATTCAACTTCATCCGTTGGTATGCCCTCCATTTAACGC
AGACTTTGATGGTGACCAAATGGCTGTGCATGTGCCTCTTGGTATAGAGGCTCAGCTAGAATCTTATATACTTATACTTT
CAACCCAAAACATACTCTCACCTGCCAACGGAAGGCCAATTATGTTGCCCTCTCAAGATATGGTGTTGGGACTTTTCTAC
GCTTCAAATTATGTAAAAGGTGCTAAAGGCGAGGGTAAGGTATTCTTCTCTAAAGAAGATGCGTTTTTGGCTTTTGAAAA
CAAAAAGATAGATATTCACGCTGTTATAAAGGTGAAGATAGGGGATACTTTTGTAGAGACAAACATAGGTAGACTTCTTA
TAAATGAGGCATTGCCAAAGGGTTATAGATTTGTGAATGAAGTTCTTGATAAGAAAAGCATATCAAAGCTTATAGCCGAT
ATTCACAAAATTTATGGTTCAGAAATCACTGCTCAAACTCTTGATAGACTCAAGGAATTTGGTTTTGAAATGGCTACAAG
GGCTGGAATATCTATAGGTATTGAAGATATGAAGATACCAAAAGCCAAGAAACGTCTTGTAGATAAAGCTTTTCACCAAA
TGGACGAAGTGCTTGATCAATATAGAAAGGGTATAATAACAAACAAAGAAAGGTACAACAAAACTATAGATATTTGGTCA
CAAACCACAGAAGATGTTACAAAGGCTATGTTCTCTGAAATAGAAAAATCTGAACAAATAGAAAACGGTAAAAAACTGCC
AGGTCTTTTCAACCCTATTTACATGATGGCAAACTCAGGTGCTCGTGGTAACAAAGACCAGTTAAGACAGTTAGCAGGTA
TGAGAGGTCTTATGGCAAAGCACTCCGGTGAGTTTATAGAAACGCCAATTACTTCAAACTTTAGAGAGGGATTATCTGTA
TTAGAATACTTCATATCTACTTACGGTGCTAGAAAAGGTCTTGCTGATACCGCTCTAAAGACATCTTTTGCTGGTTATCT
AACTAGAAGGCTTGTAGATGTGGCTCAAGATATGGTTATTAGCGAATATGATTGTGGTACTAAAAAATATGAAGTTATAG
AAGCAATAGTAGAAAGTGGTGAAGAAAAAATATCTTTGAAAGAAAGGTTGATAGGAAGAGTTTTAGCTGAGGACATATAC
GATCCAAACAGTAAAGAGCTTATAGCAAAAGCCAACGATGTTTTAGATGAAGAGCTTACAGCTAGAATACAGCAAGCTGG
TGTAGTGCAGGTCAAGGCCAGATCAGTACTAAACTGCGAATCTGAAAACGGTATATGCTCTATGTGTTATGGATGGGATT
TATCTCAAAGAAAACTTGTTTCTCCTGGAGAGGCTGTAGGTATTATAGCTGCTCAATCTATAGGTGAGCCCGGTACTCAG
CTTACAATGAGAACATTCCACATAGGCGGTGCTGCTACAGCTCAAAAGGTCCAGAGTGAACTCATTATAGAAAGTAGTGG
TATTATAAAATTCCAAGGTTTAAGGCTTTTAAAGAATAGAAATGGAGGACTTATAAACATATCTCAAGAAGGTGTAATAT
TTGTATTGGATCCAAACGGAAGGACCATAGAAAGGCATACAGTCCCTTATGCTGCAGAGATTTTGTTTAAAGATGGTTCA
GAGGTAAAGCAAGGTGACATAGTGGCAAAATGGGATCCGTTTAACACTTACATAATAGCTGAATCAAGTGGAGAGCTTGT
TTTAAAGGATATTATAGTGGATGTTACTGTAAGAGAAGAAAAAGATACTCTTACCGGTAAAACAGCCATAGTTGTATCTT
TCCTAAGAGCTAAAGACGCTCAACTGCACTCACCGAGAATAGTTATAAAGTCTGAAGATGGTAATGAGTATTCTTATGAT
TTACCGGTAAACTCTATATTAAATATACCGTTTGAAAAGCTTAAAACTATATGGGATAAGTGTTTAGCTTGTTCTGAGGC
TGAAAAGAATGATGTTCAGCACAATTACTATTATTTAGATAAATTTGTTGTACATCCAGGGGATATTATAGCGCGTATTC
CCAAAGAAACTACAAAAGTTAGAGACATAGTAGGAGGTCTTCCAAGGGTTGAAGAGTTGTTTGAAGCTAGGAAGCCTAAA
AACCCCGCTATTATATCTGAGATAGATGGTATAGTTAAGATATATGAAGATGCAGATGAGGTTATGGTAATATCGCCAAA
AGGCACTAAGAAGTACGATATAAAAAATGAGTTTATTCTGATTAAGCATGGTCAAGAAGTGAAAGAGGGTACCAAAATTA
CAGATACTATAGTTAGTGATGTTAGTGGTAAAGCTATAGTAAGAGCAAAGGGTAGTAAGATAGTGGTTTACAATAAACAA
ACAGGCCAAGAAAAAGTTTATTCTGTGCCCAAAGGTAAATTTTTACAAGTAAAGGACGGTGATTATGTAAAAGTTGGTGA
CCAATTAACAGATGGAACTCCGCTTCTTGAAGAGATACTTAAGATAAAGGGTATAGATGAGCTTCAAAAGTTCTTGTTAA
AAGAAGTTCAGATGGTGTATAAGCTTCAAGGTGTTGATATAAACGATAAACATATAGAGATAATAATTCGTCAAATGCTA
AGGAAAAGAGTAATAGTAGATCCAGGAGATAGTAGGTTTGTGGCTAACGAAGAAGTTGATGTAATAGAGTTTAACAAAGA
AGTGGAAAGAATTAGGAAAGAAGATGGTAAAATACCAAAAGCAGAGCCTATATTGGTGGGTATTACCAAGGCTGCCTTGT
CTACTAAAAGCTGGATATCTGCTGCTTCTTTCCAAGAGACTACTAGAGTTTTGACAGAAGCTGCTAGCGAAGGAAAAGTT
GATGACTTGTCAGGTATAAAGGAAAATGTTATAATTGGTAATCTTATACCTGCCGGTACTGGTCTTGAAGAGTACAAAAA
TGTAAAGATAGAGATTGCAGAGCATGTCACCCAGTTTAAGAAGCAAACTTAA

Upstream 100 bases:

>100_bases
TAAGAGAATTGAAATCGTTGGGACTAAACGTTGTGTGTGAGAATGGAGAGGCTAAAAGCTGCGATAGTGTTGATTTGGAT
AAGAAAGAGGAGGAACGTTG

Downstream 100 bases:

>100_bases
AATGCTTGCTTTTTTTGAGCTTTTATGCTAAAATATTAGCTTATTGTTTAGGAGGAGAAAGTAAATGCCAACTGTGAATC
AGCTTATAAAAGAAGGACGC

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1563; Mature: 1563

Protein sequence:

>1563_residues
MKRGLLPFNKIKLLLASPEQILSWSHGEVKRPETLNYRTLKPEKEGLFCAKIFGPLKDYECLCGKYKGKRFEGTICDRCG
VEVTKAYVRRERFGHITLATPCAHIWFLKSSPSKIGALLGLSARDIEKVIYFESYLVVEYPTPDMEATFSNSENTIPVIK
DGVTHHVKLHVVTEEQYEKEFAYSIDNRYESGMGAEFVRYVLSILDLETFAFKLKKILKPYTFGFEDLGPKMELEHKKLY
EKIIMFLADRVKLYSVGIATSLNGVQMSIEDVIHGIVSESIYLNIKTGEISNQDLGDDWYTSKDAIRYRFEYVRGQNQNI
PVFDKIQEDVRNIVLKDFSDTRVKNLVKTLKLVEGFLKSSNRPEWMILTVLPVIPPELRPLVALDGGKFATSDLNDLYRR
LINRNNRLKRLIDLDAPDIIVRNEKRMLQESVDVLIDNGKRGKVVSQHNRPLKSLSDYLKGKQGRFRQNLLGKRVDYSGR
SVIVVGPSLKMHQCGLPKIMALELFKPFVYRRLEEKGYATSIKNARKMVDQKQPEVWECLEEVVKQHPVLLNRAPTLHRM
SIQAFEPVLVEGKAIQLHPLVCPPFNADFDGDQMAVHVPLGIEAQLESYILILSTQNILSPANGRPIMLPSQDMVLGLFY
ASNYVKGAKGEGKVFFSKEDAFLAFENKKIDIHAVIKVKIGDTFVETNIGRLLINEALPKGYRFVNEVLDKKSISKLIAD
IHKIYGSEITAQTLDRLKEFGFEMATRAGISIGIEDMKIPKAKKRLVDKAFHQMDEVLDQYRKGIITNKERYNKTIDIWS
QTTEDVTKAMFSEIEKSEQIENGKKLPGLFNPIYMMANSGARGNKDQLRQLAGMRGLMAKHSGEFIETPITSNFREGLSV
LEYFISTYGARKGLADTALKTSFAGYLTRRLVDVAQDMVISEYDCGTKKYEVIEAIVESGEEKISLKERLIGRVLAEDIY
DPNSKELIAKANDVLDEELTARIQQAGVVQVKARSVLNCESENGICSMCYGWDLSQRKLVSPGEAVGIIAAQSIGEPGTQ
LTMRTFHIGGAATAQKVQSELIIESSGIIKFQGLRLLKNRNGGLINISQEGVIFVLDPNGRTIERHTVPYAAEILFKDGS
EVKQGDIVAKWDPFNTYIIAESSGELVLKDIIVDVTVREEKDTLTGKTAIVVSFLRAKDAQLHSPRIVIKSEDGNEYSYD
LPVNSILNIPFEKLKTIWDKCLACSEAEKNDVQHNYYYLDKFVVHPGDIIARIPKETTKVRDIVGGLPRVEELFEARKPK
NPAIISEIDGIVKIYEDADEVMVISPKGTKKYDIKNEFILIKHGQEVKEGTKITDTIVSDVSGKAIVRAKGSKIVVYNKQ
TGQEKVYSVPKGKFLQVKDGDYVKVGDQLTDGTPLLEEILKIKGIDELQKFLLKEVQMVYKLQGVDINDKHIEIIIRQML
RKRVIVDPGDSRFVANEEVDVIEFNKEVERIRKEDGKIPKAEPILVGITKAALSTKSWISAASFQETTRVLTEAASEGKV
DDLSGIKENVIIGNLIPAGTGLEEYKNVKIEIAEHVTQFKKQT

Sequences:

>Translated_1563_residues
MKRGLLPFNKIKLLLASPEQILSWSHGEVKRPETLNYRTLKPEKEGLFCAKIFGPLKDYECLCGKYKGKRFEGTICDRCG
VEVTKAYVRRERFGHITLATPCAHIWFLKSSPSKIGALLGLSARDIEKVIYFESYLVVEYPTPDMEATFSNSENTIPVIK
DGVTHHVKLHVVTEEQYEKEFAYSIDNRYESGMGAEFVRYVLSILDLETFAFKLKKILKPYTFGFEDLGPKMELEHKKLY
EKIIMFLADRVKLYSVGIATSLNGVQMSIEDVIHGIVSESIYLNIKTGEISNQDLGDDWYTSKDAIRYRFEYVRGQNQNI
PVFDKIQEDVRNIVLKDFSDTRVKNLVKTLKLVEGFLKSSNRPEWMILTVLPVIPPELRPLVALDGGKFATSDLNDLYRR
LINRNNRLKRLIDLDAPDIIVRNEKRMLQESVDVLIDNGKRGKVVSQHNRPLKSLSDYLKGKQGRFRQNLLGKRVDYSGR
SVIVVGPSLKMHQCGLPKIMALELFKPFVYRRLEEKGYATSIKNARKMVDQKQPEVWECLEEVVKQHPVLLNRAPTLHRM
SIQAFEPVLVEGKAIQLHPLVCPPFNADFDGDQMAVHVPLGIEAQLESYILILSTQNILSPANGRPIMLPSQDMVLGLFY
ASNYVKGAKGEGKVFFSKEDAFLAFENKKIDIHAVIKVKIGDTFVETNIGRLLINEALPKGYRFVNEVLDKKSISKLIAD
IHKIYGSEITAQTLDRLKEFGFEMATRAGISIGIEDMKIPKAKKRLVDKAFHQMDEVLDQYRKGIITNKERYNKTIDIWS
QTTEDVTKAMFSEIEKSEQIENGKKLPGLFNPIYMMANSGARGNKDQLRQLAGMRGLMAKHSGEFIETPITSNFREGLSV
LEYFISTYGARKGLADTALKTSFAGYLTRRLVDVAQDMVISEYDCGTKKYEVIEAIVESGEEKISLKERLIGRVLAEDIY
DPNSKELIAKANDVLDEELTARIQQAGVVQVKARSVLNCESENGICSMCYGWDLSQRKLVSPGEAVGIIAAQSIGEPGTQ
LTMRTFHIGGAATAQKVQSELIIESSGIIKFQGLRLLKNRNGGLINISQEGVIFVLDPNGRTIERHTVPYAAEILFKDGS
EVKQGDIVAKWDPFNTYIIAESSGELVLKDIIVDVTVREEKDTLTGKTAIVVSFLRAKDAQLHSPRIVIKSEDGNEYSYD
LPVNSILNIPFEKLKTIWDKCLACSEAEKNDVQHNYYYLDKFVVHPGDIIARIPKETTKVRDIVGGLPRVEELFEARKPK
NPAIISEIDGIVKIYEDADEVMVISPKGTKKYDIKNEFILIKHGQEVKEGTKITDTIVSDVSGKAIVRAKGSKIVVYNKQ
TGQEKVYSVPKGKFLQVKDGDYVKVGDQLTDGTPLLEEILKIKGIDELQKFLLKEVQMVYKLQGVDINDKHIEIIIRQML
RKRVIVDPGDSRFVANEEVDVIEFNKEVERIRKEDGKIPKAEPILVGITKAALSTKSWISAASFQETTRVLTEAASEGKV
DDLSGIKENVIIGNLIPAGTGLEEYKNVKIEIAEHVTQFKKQT
>Mature_1563_residues
MKRGLLPFNKIKLLLASPEQILSWSHGEVKRPETLNYRTLKPEKEGLFCAKIFGPLKDYECLCGKYKGKRFEGTICDRCG
VEVTKAYVRRERFGHITLATPCAHIWFLKSSPSKIGALLGLSARDIEKVIYFESYLVVEYPTPDMEATFSNSENTIPVIK
DGVTHHVKLHVVTEEQYEKEFAYSIDNRYESGMGAEFVRYVLSILDLETFAFKLKKILKPYTFGFEDLGPKMELEHKKLY
EKIIMFLADRVKLYSVGIATSLNGVQMSIEDVIHGIVSESIYLNIKTGEISNQDLGDDWYTSKDAIRYRFEYVRGQNQNI
PVFDKIQEDVRNIVLKDFSDTRVKNLVKTLKLVEGFLKSSNRPEWMILTVLPVIPPELRPLVALDGGKFATSDLNDLYRR
LINRNNRLKRLIDLDAPDIIVRNEKRMLQESVDVLIDNGKRGKVVSQHNRPLKSLSDYLKGKQGRFRQNLLGKRVDYSGR
SVIVVGPSLKMHQCGLPKIMALELFKPFVYRRLEEKGYATSIKNARKMVDQKQPEVWECLEEVVKQHPVLLNRAPTLHRM
SIQAFEPVLVEGKAIQLHPLVCPPFNADFDGDQMAVHVPLGIEAQLESYILILSTQNILSPANGRPIMLPSQDMVLGLFY
ASNYVKGAKGEGKVFFSKEDAFLAFENKKIDIHAVIKVKIGDTFVETNIGRLLINEALPKGYRFVNEVLDKKSISKLIAD
IHKIYGSEITAQTLDRLKEFGFEMATRAGISIGIEDMKIPKAKKRLVDKAFHQMDEVLDQYRKGIITNKERYNKTIDIWS
QTTEDVTKAMFSEIEKSEQIENGKKLPGLFNPIYMMANSGARGNKDQLRQLAGMRGLMAKHSGEFIETPITSNFREGLSV
LEYFISTYGARKGLADTALKTSFAGYLTRRLVDVAQDMVISEYDCGTKKYEVIEAIVESGEEKISLKERLIGRVLAEDIY
DPNSKELIAKANDVLDEELTARIQQAGVVQVKARSVLNCESENGICSMCYGWDLSQRKLVSPGEAVGIIAAQSIGEPGTQ
LTMRTFHIGGAATAQKVQSELIIESSGIIKFQGLRLLKNRNGGLINISQEGVIFVLDPNGRTIERHTVPYAAEILFKDGS
EVKQGDIVAKWDPFNTYIIAESSGELVLKDIIVDVTVREEKDTLTGKTAIVVSFLRAKDAQLHSPRIVIKSEDGNEYSYD
LPVNSILNIPFEKLKTIWDKCLACSEAEKNDVQHNYYYLDKFVVHPGDIIARIPKETTKVRDIVGGLPRVEELFEARKPK
NPAIISEIDGIVKIYEDADEVMVISPKGTKKYDIKNEFILIKHGQEVKEGTKITDTIVSDVSGKAIVRAKGSKIVVYNKQ
TGQEKVYSVPKGKFLQVKDGDYVKVGDQLTDGTPLLEEILKIKGIDELQKFLLKEVQMVYKLQGVDINDKHIEIIIRQML
RKRVIVDPGDSRFVANEEVDVIEFNKEVERIRKEDGKIPKAEPILVGITKAALSTKSWISAASFQETTRVLTEAASEGKV
DDLSGIKENVIIGNLIPAGTGLEEYKNVKIEIAEHVTQFKKQT

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=677, Percent_Identity=27.3264401772526, Blast_Score=182, Evalue=2e-45,
Organism=Homo sapiens, GI103471997, Length=632, Percent_Identity=26.1075949367089, Blast_Score=129, Evalue=3e-29,
Organism=Homo sapiens, GI39725938, Length=372, Percent_Identity=29.3010752688172, Blast_Score=122, Evalue=3e-27,
Organism=Escherichia coli, GI2367335, Length=1247, Percent_Identity=48.1956696070569, Blast_Score=1119, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=673, Percent_Identity=25.7057949479941, Blast_Score=174, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI25145495, Length=859, Percent_Identity=25.2619324796275, Blast_Score=164, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6324690, Length=708, Percent_Identity=24.8587570621469, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320061, Length=344, Percent_Identity=31.9767441860465, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI17530899, Length=657, Percent_Identity=26.027397260274, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI281360912, Length=686, Percent_Identity=26.0932944606414, Blast_Score=166, Evalue=2e-40,
Organism=Drosophila melanogaster, GI17647875, Length=374, Percent_Identity=27.0053475935829, Blast_Score=102, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_HYDS0 (B4U738)

Other databases:

- EMBL:   CP001130
- RefSeq:   YP_002120927.1
- ProteinModelPortal:   B4U738
- GeneID:   6743053
- GenomeReviews:   CP001130_GR
- KEGG:   hya:HY04AAS1_0259
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- ProtClustDB:   PRK00566
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 176242; Mature: 176242

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRGLLPFNKIKLLLASPEQILSWSHGEVKRPETLNYRTLKPEKEGLFCAKIFGPLKDYE
CCCCCCCHHHHEEEEECCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEHHHCCCCCHH
CLCGKYKGKRFEGTICDRCGVEVTKAYVRRERFGHITLATPCAHIWFLKSSPSKIGALLG
HHHCCCCCCEECCCHHHHCCHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCHHHHHHHC
LSARDIEKVIYFESYLVVEYPTPDMEATFSNSENTIPVIKDGVTHHVKLHVVTEEQYEKE
CCHHHHHHHEEEEEEEEEECCCCCCCEEECCCCCCCCEEECCCEEEEEEEEEECHHHHHH
FAYSIDNRYESGMGAEFVRYVLSILDLETFAFKLKKILKPYTFGFEDLGPKMELEHKKLY
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHH
EKIIMFLADRVKLYSVGIATSLNGVQMSIEDVIHGIVSESIYLNIKTGEISNQDLGDDWY
HHHHHHHHHHHHEEEEEHHCCCCCCEEEHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCC
TSKDAIRYRFEYVRGQNQNIPVFDKIQEDVRNIVLKDFSDTRVKNLVKTLKLVEGFLKSS
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
NRPEWMILTVLPVIPPELRPLVALDGGKFATSDLNDLYRRLINRNNRLKRLIDLDAPDII
CCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCCCCEE
VRNEKRMLQESVDVLIDNGKRGKVVSQHNRPLKSLSDYLKGKQGRFRQNLLGKRVDYSGR
EECHHHHHHHHHHHEECCCCCCCEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCC
SVIVVGPSLKMHQCGLPKIMALELFKPFVYRRLEEKGYATSIKNARKMVDQKQPEVWECL
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHH
EEVVKQHPVLLNRAPTLHRMSIQAFEPVLVEGKAIQLHPLVCPPFNADFDGDQMAVHVPL
HHHHHHCCEEECCCCCHHEEEHHHCCCEEECCCEEEEEEEECCCCCCCCCCCCEEEEECC
GIEAQLESYILILSTQNILSPANGRPIMLPSQDMVLGLFYASNYVKGAKGEGKVFFSKED
CCEECCCCEEEEEEECHHCCCCCCCEEEECCCCCEEEEEHHHCCCCCCCCCCEEEEECCC
AFLAFENKKIDIHAVIKVKIGDTFVETNIGRLLINEALPKGYRFVNEVLDKKSISKLIAD
EEEEEECCEEEEEEEEEEEECCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IHKIYGSEITAQTLDRLKEFGFEMATRAGISIGIEDMKIPKAKKRLVDKAFHQMDEVLDQ
HHHHHCCCHHHHHHHHHHHHCHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
YRKGIITNKERYNKTIDIWSQTTEDVTKAMFSEIEKSEQIENGKKLPGLFNPIYMMANSG
HHCCCCCCHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEECCC
ARGNKDQLRQLAGMRGLMAKHSGEFIETPITSNFREGLSVLEYFISTYGARKGLADTALK
CCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
TSFAGYLTRRLVDVAQDMVISEYDCGTKKYEVIEAIVESGEEKISLKERLIGRVLAEDIY
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
DPNSKELIAKANDVLDEELTARIQQAGVVQVKARSVLNCESENGICSMCYGWDLSQRKLV
CCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCCCCCEEEEEECCCCCCCCCC
SPGEAVGIIAAQSIGEPGTQLTMRTFHIGGAATAQKVQSELIIESSGIIKFQGLRLLKNR
CCCCEEEEEEECCCCCCCCEEEEEEEECCCHHHHHHHHHHHEEECCCEEEEECCCEEECC
NGGLINISQEGVIFVLDPNGRTIERHTVPYAAEILFKDGSEVKQGDIVAKWDPFNTYIIA
CCCEEEEECCCEEEEECCCCCEEEECCCCCEEEEEECCCCCCCCCCEEEEECCCCEEEEE
ESSGELVLKDIIVDVTVREEKDTLTGKTAIVVSFLRAKDAQLHSPRIVIKSEDGNEYSYD
CCCCCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEE
LPVNSILNIPFEKLKTIWDKCLACSEAEKNDVQHNYYYLDKFVVHPGDIIARIPKETTKV
CCHHHHHCCCHHHHHHHHHHHHHCCCCHHCCCCCCEEEEEEEEECCCHHHHHCCHHHHHH
RDIVGGLPRVEELFEARKPKNPAIISEIDGIVKIYEDADEVMVISPKGTKKYDIKNEFIL
HHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHEEEECCCCEEEECCCCCCEEECCCCEEE
IKHGQEVKEGTKITDTIVSDVSGKAIVRAKGSKIVVYNKQTGQEKVYSVPKGKFLQVKDG
EECCCHHHCCCHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCHHHHCCCCCCEEEECCC
DYVKVGDQLTDGTPLLEEILKIKGIDELQKFLLKEVQMVYKLQGVDINDKHIEIIIRQML
CEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
RKRVIVDPGDSRFVANEEVDVIEFNKEVERIRKEDGKIPKAEPILVGITKAALSTKSWIS
HHCEEECCCCCCEEECCCCCEEEHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHH
AASFQETTRVLTEAASEGKVDDLSGIKENVIIGNLIPAGTGLEEYKNVKIEIAEHVTQFK
HHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEECCCCCCCCHHHHCCCEEEHHHHHHHHH
KQT
CCC
>Mature Secondary Structure
MKRGLLPFNKIKLLLASPEQILSWSHGEVKRPETLNYRTLKPEKEGLFCAKIFGPLKDYE
CCCCCCCHHHHEEEEECCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEHHHCCCCCHH
CLCGKYKGKRFEGTICDRCGVEVTKAYVRRERFGHITLATPCAHIWFLKSSPSKIGALLG
HHHCCCCCCEECCCHHHHCCHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCHHHHHHHC
LSARDIEKVIYFESYLVVEYPTPDMEATFSNSENTIPVIKDGVTHHVKLHVVTEEQYEKE
CCHHHHHHHEEEEEEEEEECCCCCCCEEECCCCCCCCEEECCCEEEEEEEEEECHHHHHH
FAYSIDNRYESGMGAEFVRYVLSILDLETFAFKLKKILKPYTFGFEDLGPKMELEHKKLY
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHH
EKIIMFLADRVKLYSVGIATSLNGVQMSIEDVIHGIVSESIYLNIKTGEISNQDLGDDWY
HHHHHHHHHHHHEEEEEHHCCCCCCEEEHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCC
TSKDAIRYRFEYVRGQNQNIPVFDKIQEDVRNIVLKDFSDTRVKNLVKTLKLVEGFLKSS
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
NRPEWMILTVLPVIPPELRPLVALDGGKFATSDLNDLYRRLINRNNRLKRLIDLDAPDII
CCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCCCCEE
VRNEKRMLQESVDVLIDNGKRGKVVSQHNRPLKSLSDYLKGKQGRFRQNLLGKRVDYSGR
EECHHHHHHHHHHHEECCCCCCCEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCC
SVIVVGPSLKMHQCGLPKIMALELFKPFVYRRLEEKGYATSIKNARKMVDQKQPEVWECL
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHH
EEVVKQHPVLLNRAPTLHRMSIQAFEPVLVEGKAIQLHPLVCPPFNADFDGDQMAVHVPL
HHHHHHCCEEECCCCCHHEEEHHHCCCEEECCCEEEEEEEECCCCCCCCCCCCEEEEECC
GIEAQLESYILILSTQNILSPANGRPIMLPSQDMVLGLFYASNYVKGAKGEGKVFFSKED
CCEECCCCEEEEEEECHHCCCCCCCEEEECCCCCEEEEEHHHCCCCCCCCCCEEEEECCC
AFLAFENKKIDIHAVIKVKIGDTFVETNIGRLLINEALPKGYRFVNEVLDKKSISKLIAD
EEEEEECCEEEEEEEEEEEECCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IHKIYGSEITAQTLDRLKEFGFEMATRAGISIGIEDMKIPKAKKRLVDKAFHQMDEVLDQ
HHHHHCCCHHHHHHHHHHHHCHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
YRKGIITNKERYNKTIDIWSQTTEDVTKAMFSEIEKSEQIENGKKLPGLFNPIYMMANSG
HHCCCCCCHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEECCC
ARGNKDQLRQLAGMRGLMAKHSGEFIETPITSNFREGLSVLEYFISTYGARKGLADTALK
CCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
TSFAGYLTRRLVDVAQDMVISEYDCGTKKYEVIEAIVESGEEKISLKERLIGRVLAEDIY
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
DPNSKELIAKANDVLDEELTARIQQAGVVQVKARSVLNCESENGICSMCYGWDLSQRKLV
CCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCCCCCEEEEEECCCCCCCCCC
SPGEAVGIIAAQSIGEPGTQLTMRTFHIGGAATAQKVQSELIIESSGIIKFQGLRLLKNR
CCCCEEEEEEECCCCCCCCEEEEEEEECCCHHHHHHHHHHHEEECCCEEEEECCCEEECC
NGGLINISQEGVIFVLDPNGRTIERHTVPYAAEILFKDGSEVKQGDIVAKWDPFNTYIIA
CCCEEEEECCCEEEEECCCCCEEEECCCCCEEEEEECCCCCCCCCCEEEEECCCCEEEEE
ESSGELVLKDIIVDVTVREEKDTLTGKTAIVVSFLRAKDAQLHSPRIVIKSEDGNEYSYD
CCCCCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEE
LPVNSILNIPFEKLKTIWDKCLACSEAEKNDVQHNYYYLDKFVVHPGDIIARIPKETTKV
CCHHHHHCCCHHHHHHHHHHHHHCCCCHHCCCCCCEEEEEEEEECCCHHHHHCCHHHHHH
RDIVGGLPRVEELFEARKPKNPAIISEIDGIVKIYEDADEVMVISPKGTKKYDIKNEFIL
HHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHEEEECCCCEEEECCCCCCEEECCCCEEE
IKHGQEVKEGTKITDTIVSDVSGKAIVRAKGSKIVVYNKQTGQEKVYSVPKGKFLQVKDG
EECCCHHHCCCHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCHHHHCCCCCCEEEECCC
DYVKVGDQLTDGTPLLEEILKIKGIDELQKFLLKEVQMVYKLQGVDINDKHIEIIIRQML
CEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
RKRVIVDPGDSRFVANEEVDVIEFNKEVERIRKEDGKIPKAEPILVGITKAALSTKSWIS
HHCEEECCCCCCEEECCCCCEEEHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHH
AASFQETTRVLTEAASEGKVDDLSGIKENVIIGNLIPAGTGLEEYKNVKIEIAEHVTQFK
HHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEECCCCCCCCHHHHCCCEEEHHHHHHHHH
KQT
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA