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The map label for this gene is cheV [H]

Identifier: 195952576

GI number: 195952576

Start: 172455

End: 173495

Strand: Direct

Name: cheV [H]

Synonym: HY04AAS1_0196

Alternate gene names: 195952576

Gene position: 172455-173495 (Clockwise)

Preceding gene: 195952575

Following gene: 195952577

Centisome position: 11.06

GC content: 37.56

Gene sequence:

>1041_bases
ATGGAAAGCGGCATAGTAGATCGTGGCAGACTTGATGATCGTGGCACCCTTGATGATCGTGGCACCCTTGTAGCTCCTAA
AAAATCAAACAGCGGCTTACCGGAAGTATTGAGGACTGGTGCAAATGAGCTTGAAATAGTAGATTTTAGAATCTTTGAAG
ATAAAGAAGATGGTTCTCGTTATGAATGGATAATGGGAGTTAACGTAGCAAAAGTAAGGGAAGTGCTGAGGCTTCCAGAG
ATTACGAAGGTTCCAAACATGCCTCCTCAAGTAGAGGGTATGGCGGAGATAAGGGGAGAGCTGATACCTGTTGTTAGTTT
ATCAAAGTGGATGGGCTTGGCTGAGCCTCTTAAGTATAAAAAATACGTTCTTTATATGGAGTTTTTAAGAGAAAAAGTAG
GCATCATAATCCACGATGCTAAGCGTATAAGAAGAATATCGTGGGCAGATATAAAAGAGGCTCCTGTTATATTAAATCAA
AAATTGAATGGACGTATTACAGGTGTAGTGGAAACTGAAGAGGGTCTTCTTCTTATACTTGATTTTGAAGGCATACTAAA
CGATATGGGTCTTTTAAATGTTTTTGATGCAGATTATCTTGAAAAGGCAAAAGATGAGCAAGAAGAGACATTTACTATAT
ACATGGCCGATGATTCAAGCACCGCTAGAAATTTACTAAAGAGTATGCTGACGAAATTGGGTCACGAGGTGGTTATATTT
GAGAATGGAGAAGAACTTTGGAACGCTTTAGAAAATCTATTAGAAAAAGCAAAAAAAGAAAATAAAAATATATCAAACTA
CGTTCAGCTTGTGATAACAGACCTTGAAATGCCAAAAATGGATGGGCTTACCCTTACTAAGAAGTTAAAATCCACACCTG
GACTTATGCATATACCAGTGGTAGTAAATACTACTTTAAGTGACGAAGCAAACAGAATGAAAGCAAAATCTGTAGGAGCT
GATGATTTTATAGTGAAGTTTGATGCAAAAGAACTAGCAGATATTGTAAATAGAGTTGCTTTAAGGGTAAAAGGAGAGTG
A

Upstream 100 bases:

>100_bases
AAATACAAACAAAATAGCCACCAACATAAAAAGGCTTATGCTTTCTATAGAAGAAAAGCTTGACACTCTTAATAAAGAAG
AGGTCTAAGGAGGGCTTAGT

Downstream 100 bases:

>100_bases
TGTATGATACCTAATGAAATGCGTGAAATATTTGAAGAGTTTTTGGTAGAGGCAAGAGAGAATTTAGAAAAGTTAGAAAC
AGATTTATTAGAATTAGAAA

Product: response regulator receiver modulated chemotaxis protein CheW

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MESGIVDRGRLDDRGTLDDRGTLVAPKKSNSGLPEVLRTGANELEIVDFRIFEDKEDGSRYEWIMGVNVAKVREVLRLPE
ITKVPNMPPQVEGMAEIRGELIPVVSLSKWMGLAEPLKYKKYVLYMEFLREKVGIIIHDAKRIRRISWADIKEAPVILNQ
KLNGRITGVVETEEGLLLILDFEGILNDMGLLNVFDADYLEKAKDEQEETFTIYMADDSSTARNLLKSMLTKLGHEVVIF
ENGEELWNALENLLEKAKKENKNISNYVQLVITDLEMPKMDGLTLTKKLKSTPGLMHIPVVVNTTLSDEANRMKAKSVGA
DDFIVKFDAKELADIVNRVALRVKGE

Sequences:

>Translated_346_residues
MESGIVDRGRLDDRGTLDDRGTLVAPKKSNSGLPEVLRTGANELEIVDFRIFEDKEDGSRYEWIMGVNVAKVREVLRLPE
ITKVPNMPPQVEGMAEIRGELIPVVSLSKWMGLAEPLKYKKYVLYMEFLREKVGIIIHDAKRIRRISWADIKEAPVILNQ
KLNGRITGVVETEEGLLLILDFEGILNDMGLLNVFDADYLEKAKDEQEETFTIYMADDSSTARNLLKSMLTKLGHEVVIF
ENGEELWNALENLLEKAKKENKNISNYVQLVITDLEMPKMDGLTLTKKLKSTPGLMHIPVVVNTTLSDEANRMKAKSVGA
DDFIVKFDAKELADIVNRVALRVKGE
>Mature_346_residues
MESGIVDRGRLDDRGTLDDRGTLVAPKKSNSGLPEVLRTGANELEIVDFRIFEDKEDGSRYEWIMGVNVAKVREVLRLPE
ITKVPNMPPQVEGMAEIRGELIPVVSLSKWMGLAEPLKYKKYVLYMEFLREKVGIIIHDAKRIRRISWADIKEAPVILNQ
KLNGRITGVVETEEGLLLILDFEGILNDMGLLNVFDADYLEKAKDEQEETFTIYMADDSSTARNLLKSMLTKLGHEVVIF
ENGEELWNALENLLEKAKKENKNISNYVQLVITDLEMPKMDGLTLTKKLKSTPGLMHIPVVVNTTLSDEANRMKAKSVGA
DDFIVKFDAKELADIVNRVALRVKGE

Specific function: Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW function together to couple CheA activation to methyl-accepting chemotaxis protein receptor status and possible CheA-dependent phosphoryl

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 39073; Mature: 39073

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50851 CHEW ; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESGIVDRGRLDDRGTLDDRGTLVAPKKSNSGLPEVLRTGANELEIVDFRIFEDKEDGSR
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHCCCCCEEEEEEEEEECCCCCCE
YEWIMGVNVAKVREVLRLPEITKVPNMPPQVEGMAEIRGELIPVVSLSKWMGLAEPLKYK
EEEEECCCHHHHHHHHHCCCHHCCCCCCCCCCCHHHHCCCEEEEEHHHHHCCCCCHHHHH
KYVLYMEFLREKVGIIIHDAKRIRRISWADIKEAPVILNQKLNGRITGVVETEEGLLLIL
HHHHHHHHHHHHHCEEEECHHHHHHCCCCCCCCCCEEECCCCCCEEEEEEECCCCEEEEE
DFEGILNDMGLLNVFDADYLEKAKDEQEETFTIYMADDSSTARNLLKSMLTKLGHEVVIF
ECHHHHCCCCCHHHCCHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEE
ENGEELWNALENLLEKAKKENKNISNYVQLVITDLEMPKMDGLTLTKKLKSTPGLMHIPV
ECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCCCCCHHHHHHHCCCCEEEEEE
VVNTTLSDEANRMKAKSVGADDFIVKFDAKELADIVNRVALRVKGE
EEEECCCCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MESGIVDRGRLDDRGTLDDRGTLVAPKKSNSGLPEVLRTGANELEIVDFRIFEDKEDGSR
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHCCCCCEEEEEEEEEECCCCCCE
YEWIMGVNVAKVREVLRLPEITKVPNMPPQVEGMAEIRGELIPVVSLSKWMGLAEPLKYK
EEEEECCCHHHHHHHHHCCCHHCCCCCCCCCCCHHHHCCCEEEEEHHHHHCCCCCHHHHH
KYVLYMEFLREKVGIIIHDAKRIRRISWADIKEAPVILNQKLNGRITGVVETEEGLLLIL
HHHHHHHHHHHHHCEEEECHHHHHHCCCCCCCCCCEEECCCCCCEEEEEEECCCCEEEEE
DFEGILNDMGLLNVFDADYLEKAKDEQEETFTIYMADDSSTARNLLKSMLTKLGHEVVIF
ECHHHHCCCCCHHHCCHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEE
ENGEELWNALENLLEKAKKENKNISNYVQLVITDLEMPKMDGLTLTKKLKSTPGLMHIPV
ECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCCCCCHHHHHHHCCCCEEEEEE
VVNTTLSDEANRMKAKSVGADDFIVKFDAKELADIVNRVALRVKGE
EEEECCCCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8169223; 9384377; 8169224 [H]