| Definition | Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633 chromosome, complete genome. |
|---|---|
| Accession | NC_011094 |
| Length | 4,709,075 |
Click here to switch to the map view.
The map label for this gene is mrcB [H]
Identifier: 194738399
GI number: 194738399
Start: 227556
End: 230078
Strand: Direct
Name: mrcB [H]
Synonym: SeSA_A0218
Alternate gene names: 194738399
Gene position: 227556-230078 (Clockwise)
Preceding gene: 194736469
Following gene: 194735130
Centisome position: 4.83
GC content: 56.76
Gene sequence:
>2523_bases ATGGCGGGGAATGACCGCGAGCCGATTGGACGTAATGGGAAACCGTCACGTCCTGTGAAACAAAAGGTGAGCCGTCGTCG GCAGCATGACGACGATTATGATGATGACTATGAGGATGAAGAACCGATGCCGCGTAAAGGTAAGGGCAAAGGGCGTAAGC CTCGTGGCAAGCGCGGCTGGCTGTGGCTATTGCTAAAACTGTTTATCGTTTTTGTGGTGCTGTTCGCCATTTACGGCGTC TATCTGGATCAAAAAATCCGCAGCCGTATTGATGGCAAGGTCTGGCAGCTTCCGGCGGCGGTATATGGCCGGATGGTGAA CCTTGAGCCAGACATGCCTGTCAGCAAAAACGAGATGGTGAAATTGCTGGAAGCGACGCAGTATCGTCTGGTGACGAAGA TGACCCGTCCCGGCGAATTTACCGTGCAGGCCAATAGCATTGAGATGATCCGTCGTCCGTTTGACTTCCCGGACAGCAAA GAAGGGCAGGTGCGCGCGCGGCTGACGTTCAGTGACGGGCGTCTGGAAACCATCGTCAATCTGGATAACAACCGCCAGTT TGGCTTCTTCCGTCTCGATCCGCGGCTTATCACCATGCTTTCTTCGCCAAATGGCGAGCAGCGTTTATTCGTCCCGCGCA GCGGTTTCCCGGATCTGCTGGTCGATACGCTGTTGGCGACGGAAGACCGTCATTTCTATGAGCATGATGGCATTAGTCTT TACTCTATCGGGCGTGCGGTGCTGGCCAACCTGACGGCGGGACGCACGGTGCAGGGGGCCAGTACGCTAACCCAGCAGCT GGTGAAGAACCTGTTCCTCTCCAGCGAAAGATCATACTGGCGTAAAGCGAATGAAGCCTACATGGCGCTGATCATGGATG CCCGTTACAGCAAAGATCGTATCCTTGAGCTGTACATGAACGAGGTCTACCTCGGTCAAAGCGGGGACAATGAAATTCGC GGTTTTCCGCTGGCGAGCCTGTATTACTTTGGTCGTCCGGTAGAGGAACTGAGCCTCGATCAGCAGGCGTTACTGGTGGG GATGGTAAAAGGGGCGTCGATTTATAACCCGTGGCGCAACCCGAAACTGGCGCTGGAGCGTCGTAACCTGGTGCTACGCC TGTTACAGCAGCAGAAAATCATCGATCAGGAACTCTATGACATGCTGAGCGCGCGTCCGCTTGGCGTACAGCCGCGCGGC GGCGTTATTTCACCGCAGCCAGCGTTTATGCAGATGGTTCGTCAGGAACTGCAGGCGAAGCTAGGGGATAAAATTAAAGA TCTCTCCGGCGTGAAGATCTTCACCACCTTTGACTCCGTGGCGCAGGATGCCGCAGAAAAAGCCGTTGTCGAAGGCATTC CGGCGTTGAAGAAACAGCGTAAATTGAGCGATCTGGAAACCGCGATGGTGGTAGTGGATCGCTTTAGCGGCGAGGTGCGC GCGATGGTTGGCGGGGCGGAGCCGCAGTATGCCGGCTATAACCGTGCCATGCAGGCGCGCCGTTCCATCGGGTCGCTGGC GAAACCGGCGACCTATCTGACCGCGTTAAGTCAGCCGAACTTATACCGTCTGAACACCTGGATTGCCGATGCGCCGATTT CTCTGCGCCAGCCGAATGGTCAGGTCTGGTCGCCGCAGAACGACGATCGTCGCTACAGCGAAAGCGGGAAAGTGATGCTG GTGGATGCGTTAACTCGCTCAATGAACGTACCGACGGTCAATCTGGGGATGGCGTTAGGTTTACCAGCGGTAACCGATAC CTGGACGAAGCTCGGCGTGCCGAAAGATCAGCTCAATCCGGTTCCGGCGATGCTGTTAGGGGCGCTGAACCTGACGCCGA TCGAAGTGGCGCAAGCGTTCCAGACTATCGCCAGCGGCGGAAATCGCGCGCCGTTATCAGCGCTGCGTTCGGTTATTGCG GAAGATGGTAAGGTGCTGTACCAAAGTTATCCGCAAGCTGAACGCGCCGTACCGGCACAGGCGGCTTACCTGACGCTATG GACAATGCAGCAGGTCGTCCAGCGTGGTACGGGGCGTCAGCTTGGCGCGAAATATCCGGGTCTGCATCTGGCGGGTAAAA CCGGGACGACAAACAACAATGTCGATACCTGGTTTGCCGGTATCGACGGCAGCCAGGTGACTATCACCTGGGTAGGCCGT GATAACAACCAGCCGACGAAATTGTACGGTGCCAGCGGCGCGATGGCGATTTACCAGCGCTATCTGGCGAACCAGACGCC GACGCCTTTAGTTCTGACGCCGCCGGAAGATGTGGTGGATATGGGCGTTGATTACGACGGTAATTTTGTCTGTAGCGGCG GTATGCGCACTCTGCCGGTCTGGACGGACGATCCAAATACGCTGTGCCAGCAGGGCGAGATGATGCAGCAGCAACAGCAG CCGTCAGGCAATCCGTTCGATCAGTCGTCTCAGCCGCAGCAGCCTGCGCAGCAACAGCCGCCGAAAGAAGAGAAGAGCGA CGGCGTTGCCGGCTGGATTAAGGAGATGTTCGGCGGCAATTAA
Upstream 100 bases:
>100_bases GCCATCCGGCAAAAGGGTAAATTGAGAGATTTCTTCTTCTGTCGTCTGGCGGAAGAATAGAGAATCGGGCCTTTGCGCCT GTATGTTGCGGAGAAAAAGC
Downstream 100 bases:
>100_bases TCACGGTAATAGTGCCGGGTGGCGCTGTGGTTACCCGGTCTACACCGTTACGACTCCATTATGTGCGACGTAGGCCGAAT AAGACGCTTACGTCGCCATC
Product: penicillin-binding protein 1b
Products: NA
Alternate protein names: PBP-1b; PBP1b; Murein polymerase; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Peptidoglycan glycosyltransferase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 840; Mature: 839
Protein sequence:
>840_residues MAGNDREPIGRNGKPSRPVKQKVSRRRQHDDDYDDDYEDEEPMPRKGKGKGRKPRGKRGWLWLLLKLFIVFVVLFAIYGV YLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMPVSKNEMVKLLEATQYRLVTKMTRPGEFTVQANSIEMIRRPFDFPDSK EGQVRARLTFSDGRLETIVNLDNNRQFGFFRLDPRLITMLSSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISL YSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIR GFPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQKIIDQELYDMLSARPLGVQPRG GVISPQPAFMQMVRQELQAKLGDKIKDLSGVKIFTTFDSVAQDAAEKAVVEGIPALKKQRKLSDLETAMVVVDRFSGEVR AMVGGAEPQYAGYNRAMQARRSIGSLAKPATYLTALSQPNLYRLNTWIADAPISLRQPNGQVWSPQNDDRRYSESGKVML VDALTRSMNVPTVNLGMALGLPAVTDTWTKLGVPKDQLNPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIA EDGKVLYQSYPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPGLHLAGKTGTTNNNVDTWFAGIDGSQVTITWVGR DNNQPTKLYGASGAMAIYQRYLANQTPTPLVLTPPEDVVDMGVDYDGNFVCSGGMRTLPVWTDDPNTLCQQGEMMQQQQQ PSGNPFDQSSQPQQPAQQQPPKEEKSDGVAGWIKEMFGGN
Sequences:
>Translated_840_residues MAGNDREPIGRNGKPSRPVKQKVSRRRQHDDDYDDDYEDEEPMPRKGKGKGRKPRGKRGWLWLLLKLFIVFVVLFAIYGV YLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMPVSKNEMVKLLEATQYRLVTKMTRPGEFTVQANSIEMIRRPFDFPDSK EGQVRARLTFSDGRLETIVNLDNNRQFGFFRLDPRLITMLSSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISL YSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIR GFPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQKIIDQELYDMLSARPLGVQPRG GVISPQPAFMQMVRQELQAKLGDKIKDLSGVKIFTTFDSVAQDAAEKAVVEGIPALKKQRKLSDLETAMVVVDRFSGEVR AMVGGAEPQYAGYNRAMQARRSIGSLAKPATYLTALSQPNLYRLNTWIADAPISLRQPNGQVWSPQNDDRRYSESGKVML VDALTRSMNVPTVNLGMALGLPAVTDTWTKLGVPKDQLNPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIA EDGKVLYQSYPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPGLHLAGKTGTTNNNVDTWFAGIDGSQVTITWVGR DNNQPTKLYGASGAMAIYQRYLANQTPTPLVLTPPEDVVDMGVDYDGNFVCSGGMRTLPVWTDDPNTLCQQGEMMQQQQQ PSGNPFDQSSQPQQPAQQQPPKEEKSDGVAGWIKEMFGGN >Mature_839_residues AGNDREPIGRNGKPSRPVKQKVSRRRQHDDDYDDDYEDEEPMPRKGKGKGRKPRGKRGWLWLLLKLFIVFVVLFAIYGVY LDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMPVSKNEMVKLLEATQYRLVTKMTRPGEFTVQANSIEMIRRPFDFPDSKE GQVRARLTFSDGRLETIVNLDNNRQFGFFRLDPRLITMLSSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLY SIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRG FPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQKIIDQELYDMLSARPLGVQPRGG VISPQPAFMQMVRQELQAKLGDKIKDLSGVKIFTTFDSVAQDAAEKAVVEGIPALKKQRKLSDLETAMVVVDRFSGEVRA MVGGAEPQYAGYNRAMQARRSIGSLAKPATYLTALSQPNLYRLNTWIADAPISLRQPNGQVWSPQNDDRRYSESGKVMLV DALTRSMNVPTVNLGMALGLPAVTDTWTKLGVPKDQLNPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAE DGKVLYQSYPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPGLHLAGKTGTTNNNVDTWFAGIDGSQVTITWVGRD NNQPTKLYGASGAMAIYQRYLANQTPTPLVLTPPEDVVDMGVDYDGNFVCSGGMRTLPVWTDDPNTLCQQGEMMQQQQQP SGNPFDQSSQPQQPAQQQPPKEEKSDGVAGWIKEMFGGN
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG0744
COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786343, Length=847, Percent_Identity=90.2007083825266, Blast_Score=1464, Evalue=0.0, Organism=Escherichia coli, GI87082258, Length=245, Percent_Identity=35.9183673469388, Blast_Score=154, Evalue=3e-38, Organism=Escherichia coli, GI1788867, Length=515, Percent_Identity=27.1844660194175, Blast_Score=126, Evalue=5e-30, Organism=Escherichia coli, GI1789601, Length=127, Percent_Identity=37.007874015748, Blast_Score=78, Evalue=2e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011813 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 93855; Mature: 93723
Theoretical pI: Translated: 9.58; Mature: 9.58
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAGNDREPIGRNGKPSRPVKQKVSRRRQHDDDYDDDYEDEEPMPRKGKGKGRKPRGKRGW CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH LWLLLKLFIVFVVLFAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMPVSKNEMV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECHHHHCEEEECCCCCCCCHHHHH KLLEATQYRLVTKMTRPGEFTVQANSIEMIRRPFDFPDSKEGQVRARLTFSDGRLETIVN HHHHHHHHHHHHHCCCCCCEEEECCCHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEEE LDNNRQFGFFRLDPRLITMLSSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISL CCCCCEEEEEEECHHHEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCCHHHCCCEEH YSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDR HHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEECCCCCHHH ILELYMNEVYLGQSGDNEIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRN HHHHHHHHEEECCCCCCCCCCCCHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCCCCCCCC PKLALERRNLVLRLLQQQKIIDQELYDMLSARPLGVQPRGGVISPQPAFMQMVRQELQAK CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH LGDKIKDLSGVKIFTTFDSVAQDAAEKAVVEGIPALKKQRKLSDLETAMVVVDRFSGEVR HCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEE AMVGGAEPQYAGYNRAMQARRSIGSLAKPATYLTALSQPNLYRLNTWIADAPISLRQPNG EEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEEEEECCCCEEECCCC QVWSPQNDDRRYSESGKVMLVDALTRSMNVPTVNLGMALGLPAVTDTWTKLGVPKDQLNP CCCCCCCCCCHHCCCCCEEEEEHHHHCCCCCEEECHHHHCCCCHHHHHHHCCCCHHHCCC VPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSYPQAERAVPAQ HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCCCHHHCCCCH AAYLTLWTMQQVVQRGTGRQLGAKYPGLHLAGKTGTTNNNVDTWFAGIDGSQVTITWVGR HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEC DNNQPTKLYGASGAMAIYQRYLANQTPTPLVLTPPEDVVDMGVDYDGNFVCSGGMRTLPV CCCCCCEEECCCCHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCCCCCEEECCCCEEEEE WTDDPNTLCQQGEMMQQQQQPSGNPFDQSSQPQQPAQQQPPKEEKSDGVAGWIKEMFGGN EECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCHHHCCCHHHHHHHHHCCC >Mature Secondary Structure AGNDREPIGRNGKPSRPVKQKVSRRRQHDDDYDDDYEDEEPMPRKGKGKGRKPRGKRGW CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH LWLLLKLFIVFVVLFAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMPVSKNEMV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECHHHHCEEEECCCCCCCCHHHHH KLLEATQYRLVTKMTRPGEFTVQANSIEMIRRPFDFPDSKEGQVRARLTFSDGRLETIVN HHHHHHHHHHHHHCCCCCCEEEECCCHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEEE LDNNRQFGFFRLDPRLITMLSSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISL CCCCCEEEEEEECHHHEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCCHHHCCCEEH YSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDR HHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEECCCCCHHH ILELYMNEVYLGQSGDNEIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRN HHHHHHHHEEECCCCCCCCCCCCHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCCCCCCCC PKLALERRNLVLRLLQQQKIIDQELYDMLSARPLGVQPRGGVISPQPAFMQMVRQELQAK CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH LGDKIKDLSGVKIFTTFDSVAQDAAEKAVVEGIPALKKQRKLSDLETAMVVVDRFSGEVR HCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEE AMVGGAEPQYAGYNRAMQARRSIGSLAKPATYLTALSQPNLYRLNTWIADAPISLRQPNG EEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEEEEECCCCEEECCCC QVWSPQNDDRRYSESGKVMLVDALTRSMNVPTVNLGMALGLPAVTDTWTKLGVPKDQLNP CCCCCCCCCCHHCCCCCEEEEEHHHHCCCCCEEECHHHHCCCCHHHHHHHCCCCHHHCCC VPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSYPQAERAVPAQ HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCCCHHHCCCCH AAYLTLWTMQQVVQRGTGRQLGAKYPGLHLAGKTGTTNNNVDTWFAGIDGSQVTITWVGR HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEC DNNQPTKLYGASGAMAIYQRYLANQTPTPLVLTPPEDVVDMGVDYDGNFVCSGGMRTLPV CCCCCCEEECCCCHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCCCCCEEECCCCEEEEE WTDDPNTLCQQGEMMQQQQQPSGNPFDQSSQPQQPAQQQPPKEEKSDGVAGWIKEMFGGN EECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCHHHCCCHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 3882429; 8202364; 9278503; 3920658; 8645198; 9244263; 3330753; 1885547; 10037771; 10564478; 9841666 [H]