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The map label for this gene is murI [H]

Identifier: 194738355

GI number: 194738355

Start: 4217180

End: 4217962

Strand: Direct

Name: murI [H]

Synonym: SeSA_A4342

Alternate gene names: 194738355

Gene position: 4217180-4217962 (Clockwise)

Preceding gene: 194736845

Following gene: 194738097

Centisome position: 89.55

GC content: 54.66

Gene sequence:

>783_bases
GTGCTGGTATTTGATTCCGGCGTCGGTGGATTGTCGGTCTATGATGAGATTCGGCGGCTCCTGCCGGATCTCCACTATAT
ATATGCTTTCGATAACGTGGCTTTCCCCTACGGGGAAAAGAGCGAAACGTTTATCGTCGAGCGCGTTGTCGAGATTGTGA
CTGCGGTACAGCAGCGCTATCCCCTTTCACTGGCGGTGATTGCTTGCAATACCGCCAGTACGGTCTCACTTCCCGCATTA
CGTGAAAAGTTTGCCTTCCCGGTAGTGGGCGTTGTGCCTGCGATTAAACCAGCGGCGCGGCTGACCGCCAATGGCGTCGT
CGGGCTACTGGCGACGAGAGCGACGGTCAAACGTCCTTATACTCACGAGCTGATTGCGCGCTTCGCCAATGAATGTCAGA
TAGCGATGTTGGGGTCGGCAGAACTGGTGGAACTGGCGGAAGCTAAATTACATGGCGACTCGGTCTCGCTGGAAGAGCTG
CGCCGCATATTACGCCCATGGCTACGAATGCCGGAGCCGCCTGATACGGTCGTTCTGGGGTGTACGCATTTCCCTCTATT
ACGGGACGAGCTTTTGCAAGTCCTGCCCGAAGGGACGCGGTTAGTGGATTCCGGCGCGGCGATAGCGCGTCGTACAGCCT
GGCTGTTGGAACATGAAGCGCCGGATGCAAAATCAACCGATGCCAATATTGCTTATTGCATGGCAATGACGCCAGGAGCT
GAACAATTATTACCCGTTTTACAGCGTTATGGCTTTGAAACGCTCGAAAAACTGGCGGTTTAA

Upstream 100 bases:

>100_bases
AACCTGTTCGACAAAGATTACGAGACAGTTTATGGCTACCAAACTGCAGGACGAGAATACACCTTGTCTGGCAGCTACAC
CTTCTGAACCACGTCCCACC

Downstream 100 bases:

>100_bases
TGGCGTTTTGGGTAAATACCAGGCACTTGAGAAATTATTTTAAATTTCCTCTTGTCAGGCAGAAATAACTCCCTATAATG
CGCCACCACTGACACGGAAC

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLVFDSGVGGLSVYDEIRRLLPDLHYIYAFDNVAFPYGEKSETFIVERVVEIVTAVQQRYPLSLAVIACNTASTVSLPAL
REKFAFPVVGVVPAIKPAARLTANGVVGLLATRATVKRPYTHELIARFANECQIAMLGSAELVELAEAKLHGDSVSLEEL
RRILRPWLRMPEPPDTVVLGCTHFPLLRDELLQVLPEGTRLVDSGAAIARRTAWLLEHEAPDAKSTDANIAYCMAMTPGA
EQLLPVLQRYGFETLEKLAV

Sequences:

>Translated_260_residues
MLVFDSGVGGLSVYDEIRRLLPDLHYIYAFDNVAFPYGEKSETFIVERVVEIVTAVQQRYPLSLAVIACNTASTVSLPAL
REKFAFPVVGVVPAIKPAARLTANGVVGLLATRATVKRPYTHELIARFANECQIAMLGSAELVELAEAKLHGDSVSLEEL
RRILRPWLRMPEPPDTVVLGCTHFPLLRDELLQVLPEGTRLVDSGAAIARRTAWLLEHEAPDAKSTDANIAYCMAMTPGA
EQLLPVLQRYGFETLEKLAV
>Mature_260_residues
MLVFDSGVGGLSVYDEIRRLLPDLHYIYAFDNVAFPYGEKSETFIVERVVEIVTAVQQRYPLSLAVIACNTASTVSLPAL
REKFAFPVVGVVPAIKPAARLTANGVVGLLATRATVKRPYTHELIARFANECQIAMLGSAELVELAEAKLHGDSVSLEEL
RRILRPWLRMPEPPDTVVLGCTHFPLLRDELLQVLPEGTRLVDSGAAIARRTAWLLEHEAPDAKSTDANIAYCMAMTPGA
EQLLPVLQRYGFETLEKLAV

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis [H]

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family [H]

Homologues:

Organism=Escherichia coli, GI87082355, Length=260, Percent_Identity=91.1538461538461, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391 [H]

Pfam domain/function: PF01177 Asp_Glu_race [H]

EC number: =5.1.1.3 [H]

Molecular weight: Translated: 28596; Mature: 28596

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00923 ASP_GLU_RACEMASE_1 ; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVFDSGVGGLSVYDEIRRLLPDLHYIYAFDNVAFPYGEKSETFIVERVVEIVTAVQQRY
CEEECCCCCCHHHHHHHHHHHCHHHEEEEECCEECCCCCCCHHHHHHHHHHHHHHHHHCC
PLSLAVIACNTASTVSLPALREKFAFPVVGVVPAIKPAARLTANGVVGLLATRATVKRPY
CCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCH
THELIARFANECQIAMLGSAELVELAEAKLHGDSVSLEELRRILRPWLRMPEPPDTVVLG
HHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEC
CTHFPLLRDELLQVLPEGTRLVDSGAAIARRTAWLLEHEAPDAKSTDANIAYCMAMTPGA
CCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCH
EQLLPVLQRYGFETLEKLAV
HHHHHHHHHHCHHHHHHHCC
>Mature Secondary Structure
MLVFDSGVGGLSVYDEIRRLLPDLHYIYAFDNVAFPYGEKSETFIVERVVEIVTAVQQRY
CEEECCCCCCHHHHHHHHHHHCHHHEEEEECCEECCCCCCCHHHHHHHHHHHHHHHHHCC
PLSLAVIACNTASTVSLPALREKFAFPVVGVVPAIKPAARLTANGVVGLLATRATVKRPY
CCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCH
THELIARFANECQIAMLGSAELVELAEAKLHGDSVSLEELRRILRPWLRMPEPPDTVVLG
HHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEC
CTHFPLLRDELLQVLPEGTRLVDSGAAIARRTAWLLEHEAPDAKSTDANIAYCMAMTPGA
CCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCH
EQLLPVLQRYGFETLEKLAV
HHHHHHHHHHCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA