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The map label for this gene is sglT [H]

Identifier: 194738311

GI number: 194738311

Start: 1175116

End: 1176612

Strand: Reverse

Name: sglT [H]

Synonym: SeSA_A1193

Alternate gene names: 194738311

Gene position: 1176612-1175116 (Counterclockwise)

Preceding gene: 194736640

Following gene: 194737668

Centisome position: 24.99

GC content: 45.42

Gene sequence:

>1497_bases
ATGATTACACATTCTTTCGGCATCGTTAATTATCTTGTATTATTTGGCTACCTCCTGGCCATGATGTTAGTCGGTGTCTA
TTTTTCCAGACGGCAAAAAACAGCAGACGATTATTTTCGCGGTGGTGGCCGGGTTCCTGGTTGGGCGGCTGGGGTCAGTG
TATTTGCTACTACGTTAAGCTCAATTACATTTATGTCAATTCCTGCCAAAGCGTTTACTTCCGACTGGACGTTTATCATT
GGTCAGTATCTGGCTATCGCAATTTTACCGCTGGTTTTTTATTTCTATATTCCGTTTTTTCGGAAATTGAAAGTCACATC
AGCCTATGAATATCTCGAAGCACGGTTCGATGTGCGCTGCCGTCTATTCGCCAGCATGTCATTTATGTTGTTTCATATCG
GACGTATCGCCATTATCACTTTCCTCACCGTGCTGGCCTTGCGCCCCTTCATCGCTATAGACCCGGTGATTTTGGTACTG
TTGATTAGCGTGATGTGTATCATTTATACCTGGATGGGTGGAATTGAAGGAGTAATATGGACTGATGTTATTCAAGGCCT
CTTACTTTCTGGCAGCGCGATACTGATTTTTATAGTGATATGTCTCAAAGTCCAGGGCGGCATTGGTGAAATTTTTACGG
TGACGCAGCAGGCGGATAAATTCTTTCCGGCTACGCAGTTCCACTGGAGCTGGACGGAAAGCACAGTACCCGTATTGATT
ATTGGTTTTCTGTTTGCCAATATTCAGCAATTTACTGCCAGTCAGGATGTGGTCCAACGCTATATCGTGACTGACTCCAT
AGAGGAAACGAAGAAAACATTACTTACAAATGCCAAACTGGTTGCTGTGATCCCTGTTTTCTTTTTTGCTATCGGCTCGG
CATTGTTTGTCTACTATCAGCAACATCCACAATTATTACCGGCGGGATTCAACACTGGCGGCATTTTACCCTTATTCGTG
GTCACCGAAATGCCAGTCGGCATTGCAGGGTTGATAATCGCCGCTATTTTCGCTGCTGCGCAGTCCAGTATCTCCAGCAG
CTTAAACAGCATTTCTAGTTGTTTTAATTCCGATATCTATCAGCGTTTGAGTCATAAAAAAAGAACGCCTGAAAACCGTA
TGAAAATAGCTAAGTTAGTTATTCTGGTCGCGGGCCTGATAAGTAGCGCGGCCTCGGTATGGCTGGTCATGGCCGATGAA
TCAGAAATCTGGGATGCATTTAATAGTCTGATAGGTCTGATGGGAGGGCCAATGACCGGTCTGTTCATGCTGGGCATTTT
CTTTAAACGAGCAAATGCCGGGAGTGCGGTTTTAGGAATTATTATCAGCGTCATTACCGTGCTGGGCGCACGCTATGCCA
CTGACCTTAACTTCTTCTTTTATGGGGTCATTGGCTCGCTAAGCGTGGTGATCAGCGGCGTTATTTTCGCCCCGTTATTT
GCCCCGGCACCGCCATTGACGCTGGATGAAAAACCTGAACCAAAGGTGACATTATGA

Upstream 100 bases:

>100_bases
TATTACTTGATCTGAATATCGTATCGTCTGAATGATGGGAAGATAAAAATACACAGACGATGACCGCAACTCTACTCAAA
ACCATAAGCAGGAAAGAACT

Downstream 100 bases:

>100_bases
TTTCATGATACCACGCTATACCGACACAGCACACGGTGACGCCAACGCCCGGGGCGACAATACCGGGCCAAGTATAAACC
ATCCGTCAAATGGCGCGCTA

Product: sodium-glucose/galactose cotransporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MITHSFGIVNYLVLFGYLLAMMLVGVYFSRRQKTADDYFRGGGRVPGWAAGVSVFATTLSSITFMSIPAKAFTSDWTFII
GQYLAIAILPLVFYFYIPFFRKLKVTSAYEYLEARFDVRCRLFASMSFMLFHIGRIAIITFLTVLALRPFIAIDPVILVL
LISVMCIIYTWMGGIEGVIWTDVIQGLLLSGSAILIFIVICLKVQGGIGEIFTVTQQADKFFPATQFHWSWTESTVPVLI
IGFLFANIQQFTASQDVVQRYIVTDSIEETKKTLLTNAKLVAVIPVFFFAIGSALFVYYQQHPQLLPAGFNTGGILPLFV
VTEMPVGIAGLIIAAIFAAAQSSISSSLNSISSCFNSDIYQRLSHKKRTPENRMKIAKLVILVAGLISSAASVWLVMADE
SEIWDAFNSLIGLMGGPMTGLFMLGIFFKRANAGSAVLGIIISVITVLGARYATDLNFFFYGVIGSLSVVISGVIFAPLF
APAPPLTLDEKPEPKVTL

Sequences:

>Translated_498_residues
MITHSFGIVNYLVLFGYLLAMMLVGVYFSRRQKTADDYFRGGGRVPGWAAGVSVFATTLSSITFMSIPAKAFTSDWTFII
GQYLAIAILPLVFYFYIPFFRKLKVTSAYEYLEARFDVRCRLFASMSFMLFHIGRIAIITFLTVLALRPFIAIDPVILVL
LISVMCIIYTWMGGIEGVIWTDVIQGLLLSGSAILIFIVICLKVQGGIGEIFTVTQQADKFFPATQFHWSWTESTVPVLI
IGFLFANIQQFTASQDVVQRYIVTDSIEETKKTLLTNAKLVAVIPVFFFAIGSALFVYYQQHPQLLPAGFNTGGILPLFV
VTEMPVGIAGLIIAAIFAAAQSSISSSLNSISSCFNSDIYQRLSHKKRTPENRMKIAKLVILVAGLISSAASVWLVMADE
SEIWDAFNSLIGLMGGPMTGLFMLGIFFKRANAGSAVLGIIISVITVLGARYATDLNFFFYGVIGSLSVVISGVIFAPLF
APAPPLTLDEKPEPKVTL
>Mature_498_residues
MITHSFGIVNYLVLFGYLLAMMLVGVYFSRRQKTADDYFRGGGRVPGWAAGVSVFATTLSSITFMSIPAKAFTSDWTFII
GQYLAIAILPLVFYFYIPFFRKLKVTSAYEYLEARFDVRCRLFASMSFMLFHIGRIAIITFLTVLALRPFIAIDPVILVL
LISVMCIIYTWMGGIEGVIWTDVIQGLLLSGSAILIFIVICLKVQGGIGEIFTVTQQADKFFPATQFHWSWTESTVPVLI
IGFLFANIQQFTASQDVVQRYIVTDSIEETKKTLLTNAKLVAVIPVFFFAIGSALFVYYQQHPQLLPAGFNTGGILPLFV
VTEMPVGIAGLIIAAIFAAAQSSISSSLNSISSCFNSDIYQRLSHKKRTPENRMKIAKLVILVAGLISSAASVWLVMADE
SEIWDAFNSLIGLMGGPMTGLFMLGIFFKRANAGSAVLGIIISVITVLGARYATDLNFFFYGVIGSLSVVISGVIFAPLF
APAPPLTLDEKPEPKVTL

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI256985183, Length=463, Percent_Identity=27.4298056155508, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI167466278, Length=512, Percent_Identity=27.734375, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4507035, Length=452, Percent_Identity=26.9911504424779, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI157671931, Length=470, Percent_Identity=24.2553191489362, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI14140236, Length=465, Percent_Identity=23.010752688172, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI4507031, Length=454, Percent_Identity=25.5506607929515, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI206597483, Length=447, Percent_Identity=24.1610738255034, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI109659839, Length=486, Percent_Identity=22.8395061728395, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI109659836, Length=470, Percent_Identity=23.4042553191489, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI110835708, Length=462, Percent_Identity=23.8095238095238, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4507033, Length=471, Percent_Identity=22.9299363057325, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI206597487, Length=375, Percent_Identity=24.8, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI17941285, Length=454, Percent_Identity=22.6872246696035, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1790113, Length=467, Percent_Identity=22.2698072805139, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1787251, Length=390, Percent_Identity=22.5641025641026, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32566512, Length=372, Percent_Identity=28.494623655914, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI115533094, Length=422, Percent_Identity=23.696682464455, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI115533096, Length=314, Percent_Identity=22.2929936305732, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24651739, Length=467, Percent_Identity=28.9079229122056, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI221459588, Length=479, Percent_Identity=26.9311064718163, Blast_Score=158, Evalue=7e-39,
Organism=Drosophila melanogaster, GI221459584, Length=479, Percent_Identity=28.1837160751566, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24645928, Length=460, Percent_Identity=26.9565217391304, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28573698, Length=450, Percent_Identity=25.3333333333333, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI221459586, Length=482, Percent_Identity=24.896265560166, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24651741, Length=429, Percent_Identity=25.4079254079254, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI281362918, Length=464, Percent_Identity=27.801724137931, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24640370, Length=469, Percent_Identity=25.7995735607676, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24641117, Length=451, Percent_Identity=27.2727272727273, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI221459582, Length=480, Percent_Identity=27.0833333333333, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI28574994, Length=460, Percent_Identity=26.5217391304348, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI161076631, Length=486, Percent_Identity=26.1316872427983, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24650192, Length=482, Percent_Identity=23.0290456431535, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI221379702, Length=468, Percent_Identity=26.2820512820513, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281362054, Length=445, Percent_Identity=24.9438202247191, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI281362052, Length=445, Percent_Identity=24.9438202247191, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI281362050, Length=445, Percent_Identity=24.9438202247191, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24648056, Length=445, Percent_Identity=24.9438202247191, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI21356827, Length=445, Percent_Identity=24.9438202247191, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI19920916, Length=479, Percent_Identity=27.9749478079332, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281364280, Length=484, Percent_Identity=25.8264462809917, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 54702; Mature: 54702

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]