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The map label for this gene is yihV [H]

Identifier: 194738247

GI number: 194738247

Start: 4113162

End: 4114058

Strand: Direct

Name: yihV [H]

Synonym: SeSA_A4235

Alternate gene names: 194738247

Gene position: 4113162-4114058 (Clockwise)

Preceding gene: 194736407

Following gene: 194734055

Centisome position: 87.35

GC content: 56.97

Gene sequence:

>897_bases
ATGGTTCGTATTGCTTGTGTAGGTATTACCGTGATGGATCGCATCTATTACGTGGAAGGATTACCGACAGAAGGGGGTAA
ATATGTGGCGAAGCGCTATACGGAAGTGGGCGGCGGGCCTGCGGCGACCGCTGCCGTGGCTGCGGCGAAATTGGGCGCGC
AGGTGGACTTTATTGGCCGTGTGGGCGATGACGACACCGGAAACAGCCTGCTGGCGGAACTGGAATCCCTGGGGGTAAAT
ACCCGCTATACCCGCCGCTACACGCAGGCCATGTCGTCGCAGTCAGCGATTATGGTGGATGCCAAAGGAGAGCGGATTAT
CGTTAATTATCCCAGCCCGGATTTATTGCCTGACGCCGACTGGCTTAACGACATCGATTTTTCGCAGTGGGATGTGGTGT
TGGCGGATGTGCGCTGGCATGACGGCGCAAAACAGGCGTTTACGCTGGCGCGTCAGGCTGGCGTCATGACTGTTCTTGAT
GGCGATATTACGCCGCAGGATATTAGCGAGCTGGTGGCGTTAAGCGACCACGCCGCCTTCTCCGAGCCAGGGCTGGCACG
CCTGACGGGGATGAGCGAAGCCATTGATGCGCTAAAAAAAGCACAAATGCTCACAAATGGACATGTCTATGTCACGCGAG
GCAGTGAAGGCTGCAACTGGTTGGAAAAAGCGGCGGTACGCCACCAACCGGGTTTTACCGTGGAGGTGGTGGATACTACC
GGCGCGGGCGATGTTTTTCATGGCGCACTGGCATTTGGCCTGGCAAGCGGATACGCCATCGAAGAGGCTGTCAGATTCGC
CAGCGGCGTTGCCGCGCTGAAGTGTACGCGCCCAGGTGGCCGGGCGGGTATCCCTGATTGTGAGCAAACCCGATCTTTCT
TGTCACTTTTTGTATAA

Upstream 100 bases:

>100_bases
GATCGTATTTGTAATTTATAGTCAAAAAATTGACAGCCGTCACTTTTTAAACATTTCGTGAAATTAAAATGAGCACATCG
AAAATGCTTGAGGAATGACC

Downstream 100 bases:

>100_bases
TATGAGCAGTAGGAAGCTTTTAGAGGAATGCTCATGAGTCTTACCGAACTGACCGGTAATCCGCGACACGATCGGCTGTT
AATGCTAATTGATGAGCGCG

Product: kinase, PfkB family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MVRIACVGITVMDRIYYVEGLPTEGGKYVAKRYTEVGGGPAATAAVAAAKLGAQVDFIGRVGDDDTGNSLLAELESLGVN
TRYTRRYTQAMSSQSAIMVDAKGERIIVNYPSPDLLPDADWLNDIDFSQWDVVLADVRWHDGAKQAFTLARQAGVMTVLD
GDITPQDISELVALSDHAAFSEPGLARLTGMSEAIDALKKAQMLTNGHVYVTRGSEGCNWLEKAAVRHQPGFTVEVVDTT
GAGDVFHGALAFGLASGYAIEEAVRFASGVAALKCTRPGGRAGIPDCEQTRSFLSLFV

Sequences:

>Translated_298_residues
MVRIACVGITVMDRIYYVEGLPTEGGKYVAKRYTEVGGGPAATAAVAAAKLGAQVDFIGRVGDDDTGNSLLAELESLGVN
TRYTRRYTQAMSSQSAIMVDAKGERIIVNYPSPDLLPDADWLNDIDFSQWDVVLADVRWHDGAKQAFTLARQAGVMTVLD
GDITPQDISELVALSDHAAFSEPGLARLTGMSEAIDALKKAQMLTNGHVYVTRGSEGCNWLEKAAVRHQPGFTVEVVDTT
GAGDVFHGALAFGLASGYAIEEAVRFASGVAALKCTRPGGRAGIPDCEQTRSFLSLFV
>Mature_298_residues
MVRIACVGITVMDRIYYVEGLPTEGGKYVAKRYTEVGGGPAATAAVAAAKLGAQVDFIGRVGDDDTGNSLLAELESLGVN
TRYTRRYTQAMSSQSAIMVDAKGERIIVNYPSPDLLPDADWLNDIDFSQWDVVLADVRWHDGAKQAFTLARQAGVMTVLD
GDITPQDISELVALSDHAAFSEPGLARLTGMSEAIDALKKAQMLTNGHVYVTRGSEGCNWLEKAAVRHQPGFTVEVVDTT
GAGDVFHGALAFGLASGYAIEEAVRFASGVAALKCTRPGGRAGIPDCEQTRSFLSLFV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=295, Percent_Identity=29.4915254237288, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI4557693, Length=301, Percent_Identity=26.578073089701, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI5670342, Length=301, Percent_Identity=25.5813953488372, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI87082343, Length=298, Percent_Identity=85.2348993288591, Blast_Score=513, Evalue=1e-147,
Organism=Escherichia coli, GI1790193, Length=299, Percent_Identity=28.4280936454849, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789432, Length=295, Percent_Identity=28.135593220339, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=304, Percent_Identity=32.2368421052632, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24583886, Length=305, Percent_Identity=25.9016393442623, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24662680, Length=298, Percent_Identity=23.8255033557047, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20128807, Length=294, Percent_Identity=26.8707482993197, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: NA

Molecular weight: Translated: 31752; Mature: 31752

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRIACVGITVMDRIYYVEGLPTEGGKYVAKRYTEVGGGPAATAAVAAAKLGAQVDFIGR
CEEEEEEHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEC
VGDDDTGNSLLAELESLGVNTRYTRRYTQAMSSQSAIMVDAKGERIIVNYPSPDLLPDAD
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCH
WLNDIDFSQWDVVLADVRWHDGAKQAFTLARQAGVMTVLDGDITPQDISELVALSDHAAF
HCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCC
SEPGLARLTGMSEAIDALKKAQMLTNGHVYVTRGSEGCNWLEKAAVRHQPGFTVEVVDTT
CCCCHHHHHCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEEECC
GAGDVFHGALAFGLASGYAIEEAVRFASGVAALKCTRPGGRAGIPDCEQTRSFLSLFV
CCCHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MVRIACVGITVMDRIYYVEGLPTEGGKYVAKRYTEVGGGPAATAAVAAAKLGAQVDFIGR
CEEEEEEHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEC
VGDDDTGNSLLAELESLGVNTRYTRRYTQAMSSQSAIMVDAKGERIIVNYPSPDLLPDAD
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCH
WLNDIDFSQWDVVLADVRWHDGAKQAFTLARQAGVMTVLDGDITPQDISELVALSDHAAF
HCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCC
SEPGLARLTGMSEAIDALKKAQMLTNGHVYVTRGSEGCNWLEKAAVRHQPGFTVEVVDTT
CCCCHHHHHCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEEECC
GAGDVFHGALAFGLASGYAIEEAVRFASGVAALKCTRPGGRAGIPDCEQTRSFLSLFV
CCCHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]