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The map label for this gene is sgbE [H]

Identifier: 194738071

GI number: 194738071

Start: 3742159

End: 3742854

Strand: Direct

Name: sgbE [H]

Synonym: SeSA_A3875

Alternate gene names: 194738071

Gene position: 3742159-3742854 (Clockwise)

Preceding gene: 194737478

Following gene: 194737873

Centisome position: 79.47

GC content: 58.48

Gene sequence:

>696_bases
ATGTTAGAGCAACTGAAAGCCGAGGTGCTGGCGGCAAACCTGGCCCTCCCGGCGCACGGGCTGGTCACCTTTACCTGGGG
CAACGTCAGCGCGGTCGATGAGACGCGCAAACTGATGGTCATCAAGCCTTCCGGCGTTGAATATGAGGTGATGACCGCCG
ACGATATGGTGGTGGTAGAGATCGCCAGCGGTAAGGTCGTTGAAGGCCATAAAAAACCGTCGTCCGATACCGCGACCCAT
CTGGCGCTCTATCGCCGCTATCCGCAGATCGGCGGGATCGTGCATACCCATTCCCGCCATGCGACGATCTGGTCGCAGGC
CGGGCTCGATCTGCCCGCCTGGGGCACCACCCACGCCGACTATTTCTATGGCGCGATCCCCTGTACCCGACTGATGACCG
TTGAGGAAATTAACGGCGAGTACGAGTATCAGACCGGCGAGGTGATTATTAAAACCTTTGAAGAGCGCGGTCTGGATCCG
GCGCAAATCCCGGCGGTATTGGTTCATTCACACGGCCCGTTTGCCTGGGGTAAAAATGCCGCCGATGCCGTCCACAACGC
CGTGGTGCTTGAGGAGTGCGCCTATATGGGGCTGTTCTCGCGCCAGCTGGCCCCGCAGCTACCGGATATGCAATCTGAAC
TGCTCGATAAACACTATCTGCGTAAACATGGCGCGAATGCCTATTACGGGCAGTAA

Upstream 100 bases:

>100_bases
TTCTGATTGAGATGTGGACAGAGAAATCCAGTGAGCCGGTGCTGGAAATTATCCAGGCCCGCCGCTGGATTGAATCACGG
ATGCAGGAAGGAGGTTTCAC

Downstream 100 bases:

>100_bases
CAGCCTATGTCGGATGGCGGCTGCGCCTTATCCGACCTACAAAACTTGCAATATCAATACGTTGCGATGAACTCTTGTAG
GCCCGATAAGCAAAGCGCCA

Product: L-ribulose-5-phosphate 4-epimerase

Products: NA

Alternate protein names: Phosphoribulose isomerase [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MLEQLKAEVLAANLALPAHGLVTFTWGNVSAVDETRKLMVIKPSGVEYEVMTADDMVVVEIASGKVVEGHKKPSSDTATH
LALYRRYPQIGGIVHTHSRHATIWSQAGLDLPAWGTTHADYFYGAIPCTRLMTVEEINGEYEYQTGEVIIKTFEERGLDP
AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPDMQSELLDKHYLRKHGANAYYGQ

Sequences:

>Translated_231_residues
MLEQLKAEVLAANLALPAHGLVTFTWGNVSAVDETRKLMVIKPSGVEYEVMTADDMVVVEIASGKVVEGHKKPSSDTATH
LALYRRYPQIGGIVHTHSRHATIWSQAGLDLPAWGTTHADYFYGAIPCTRLMTVEEINGEYEYQTGEVIIKTFEERGLDP
AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPDMQSELLDKHYLRKHGANAYYGQ
>Mature_231_residues
MLEQLKAEVLAANLALPAHGLVTFTWGNVSAVDETRKLMVIKPSGVEYEVMTADDMVVVEIASGKVVEGHKKPSSDTATH
LALYRRYPQIGGIVHTHSRHATIWSQAGLDLPAWGTTHADYFYGAIPCTRLMTVEEINGEYEYQTGEVIIKTFEERGLDP
AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPDMQSELLDKHYLRKHGANAYYGQ

Specific function: Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate. May be involved in the utilization of 2,3- diketo-L-gulonate [H]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790008, Length=231, Percent_Identity=93.0735930735931, Blast_Score=446, Evalue=1e-127,
Organism=Escherichia coli, GI1786247, Length=231, Percent_Identity=76.6233766233766, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1790642, Length=230, Percent_Identity=63.4782608695652, Blast_Score=305, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004661 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =5.1.3.4 [H]

Molecular weight: Translated: 25499; Mature: 25499

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQLKAEVLAANLALPAHGLVTFTWGNVSAVDETRKLMVIKPSGVEYEVMTADDMVVVE
CHHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCCEEEEECCCCCEEEEEECCCEEEEE
IASGKVVEGHKKPSSDTATHLALYRRYPQIGGIVHTHSRHATIWSQAGLDLPAWGTTHAD
ECCCCEEECCCCCCCHHHHHHHHHHHCHHHCCEEEECCCCEEEHHHCCCCCCCCCCCCCC
YFYGAIPCTRLMTVEEINGEYEYQTGEVIIKTFEERGLDPAQIPAVLVHSHGPFAWGKNA
CEECCCCHHHHEEHHHCCCEEEEECCHHHEEEHHHHCCCHHHCCEEEEECCCCCCCCCCH
ADAVHNAVVLEECAYMGLFSRQLAPQLPDMQSELLDKHYLRKHGANAYYGQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLEQLKAEVLAANLALPAHGLVTFTWGNVSAVDETRKLMVIKPSGVEYEVMTADDMVVVE
CHHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCCEEEEECCCCCEEEEEECCCEEEEE
IASGKVVEGHKKPSSDTATHLALYRRYPQIGGIVHTHSRHATIWSQAGLDLPAWGTTHAD
ECCCCEEECCCCCCCHHHHHHHHHHHCHHHCCEEEECCCCEEEHHHCCCCCCCCCCCCCC
YFYGAIPCTRLMTVEEINGEYEYQTGEVIIKTFEERGLDPAQIPAVLVHSHGPFAWGKNA
CEECCCCHHHHEEHHHCCCEEEEECCHHHEEEHHHHCCCHHHCCEEEEECCCCCCCCCCH
ADAVHNAVVLEECAYMGLFSRQLAPQLPDMQSELLDKHYLRKHGANAYYGQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 11741871 [H]