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The map label for this gene is tsr [H]

Identifier: 194738049

GI number: 194738049

Start: 4646466

End: 4648127

Strand: Direct

Name: tsr [H]

Synonym: SeSA_A4786

Alternate gene names: 194738049

Gene position: 4646466-4648127 (Clockwise)

Preceding gene: 194736829

Following gene: 194737223

Centisome position: 98.67

GC content: 55.42

Gene sequence:

>1662_bases
ATGTTAAAGCGAATTAAAATTGTTACCAGCTTACTGCTGGTATTGGCGCTATTTGGCCTTTTACAACTGACATCCGGCGG
GCTGTTCTTCAACTCGCTGAAGAATGACAAAGAAAACTTCACCGTATTGCAAACCATTCGTCAGCAGCAGTCTGCCCTGA
ATTCAACCTGGGTGGAGCTGTTGCAAACGCGTAATACCCTGAATCGCGCGGGTATCCGCTGGATGATGGACCAGAGCAAT
ATTGGCAGCGGCGCAACTGTCGCTGAACTGATGCAGGGGGCGACCAATGCGCTGAAGCTCACCGAAAAAAACTGGGCGCA
GTATGAGTCGTTACCGCGCGATCCACGTCAGAGTGAGGCGGCTTTCCTTGAGATCAAACGAACCTATGATATCTACCACG
GCGCGTTGGCGGAGCTTATTCAGCTTCTTGGCGCGGGTAAGATTAACGAGTTTTTTGATCAACCGACTCAAAGCTATCAG
GACGCTTTTGAGAAGCAGTACATGGCCTATATGCAGCAAAACGATCGTCTGTACGATATTGCTGTTGAGGATAACAACAG
TTCCTACAACCAGGCGATGTGGGTACTGGTCAGTGTGCTGATTGCCGTTCTGGTGGTCATTATCGCCGTCTGGTTCGGCA
TCAAACTGTCGCTTATCGCCCCGATGAATCGTCTGATTGAAAGTATTCGCCATATCGCCAGCGGCGATCTGGTGAAACGT
ATTGATGTGGAAGGCTCTAACGAAATGGGGCAACTGGCGGACAACTTACGTCATATGCAGAGCGAACTGGTGCGTACCGT
GGGCGATGTGCGCAACGGCGCCAACGCCATTTACAGCGGCGCCAGCGAGATTGCGATGGGCAACAACGATCTCTCTTCCC
GTACTGAGCAGCAGGCAGCGTCTCTGGAAGAGACCGCCGCCAGTATGGAACAACTGACCGCGACCGTGAAACAGAACGCC
GAAAACGCCCGTCAGGCCAGTCACCTGGCATTGAGCGCCTCTGAAACAGCGCAAAAAGGCGGCAAAGTGGTGGATAACGT
CGTACAAACAATGCGCGATATCGCCTCCAGTTCGCAGAAAATCGCCGATATTATCAGCGTAATCGACGGTATTGCTTTCC
AGACCAATATCCTGGCGCTGAATGCGGCGGTAGAAGCGGCGCGCGCAGGCGAGCAGGGACGCGGGTTCGCGGTGGTGGCC
GGTGAAGTCCGTAATCTGGCCCAGCGTAGCGCGCAGGCGGCACGGGAGATCAAGAGTCTGATTGAGGATTCCGTGAGCCG
TGTTGATGTGGGTTCGACGCTGGTCGAAAGCGCCGGTGAAACCATGGATGAGATCGTCAATGCAGTGACCCGCGTGACCG
ATATCATGGGCGAGATTGCCTCGGCGTCCGACGAGCAAAGCCGTGGTATCGACCAGGTGGGCCTGGCGGTAGCGGAGATG
GATCGCGTAACGCAGCAGAACGCCTCGCTGGTGGAAGAATCCGCCGCCGCGGCTGCGGCGCTGGAAGAGCAAGCCAGCCG
TCTGACCCAGGCCGTCGCGGTGTTCCGTATTCAACAGCAACAGCAGCGTGCGCGTGAAGTGGCAGCGGTAAAAACCCCGG
CAGCCGTGTCGTCACCAAAGGCCGCTGTGGCCGATGGCAGCGATAATTGGGAAACGTTTTAA

Upstream 100 bases:

>100_bases
CGACTTCACTGAGCTAATCGTGATATTAATGGCGCGCATCCCATAAAGTTTTCCCTTTCCAGGCCGAAAATTCTGTATCT
GTCTAGCGGAAAGAGAAAAC

Downstream 100 bases:

>100_bases
GGGCGTATGGTGAACAGTCGGCCTACAGATGACCGTAGGCCGAATGAGATGCTCACACTTTTGCCTGATGGCGCTTCGCT
TATCAGGCCTGGCAGTCCGC

Product: methyl-accepting chemotaxis protein I

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MLKRIKIVTSLLLVLALFGLLQLTSGGLFFNSLKNDKENFTVLQTIRQQQSALNSTWVELLQTRNTLNRAGIRWMMDQSN
IGSGATVAELMQGATNALKLTEKNWAQYESLPRDPRQSEAAFLEIKRTYDIYHGALAELIQLLGAGKINEFFDQPTQSYQ
DAFEKQYMAYMQQNDRLYDIAVEDNNSSYNQAMWVLVSVLIAVLVVIIAVWFGIKLSLIAPMNRLIESIRHIASGDLVKR
IDVEGSNEMGQLADNLRHMQSELVRTVGDVRNGANAIYSGASEIAMGNNDLSSRTEQQAASLEETAASMEQLTATVKQNA
ENARQASHLALSASETAQKGGKVVDNVVQTMRDIASSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRNLAQRSAQAAREIKSLIEDSVSRVDVGSTLVESAGETMDEIVNAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEM
DRVTQQNASLVEESAAAAAALEEQASRLTQAVAVFRIQQQQQRAREVAAVKTPAAVSSPKAAVADGSDNWETF

Sequences:

>Translated_553_residues
MLKRIKIVTSLLLVLALFGLLQLTSGGLFFNSLKNDKENFTVLQTIRQQQSALNSTWVELLQTRNTLNRAGIRWMMDQSN
IGSGATVAELMQGATNALKLTEKNWAQYESLPRDPRQSEAAFLEIKRTYDIYHGALAELIQLLGAGKINEFFDQPTQSYQ
DAFEKQYMAYMQQNDRLYDIAVEDNNSSYNQAMWVLVSVLIAVLVVIIAVWFGIKLSLIAPMNRLIESIRHIASGDLVKR
IDVEGSNEMGQLADNLRHMQSELVRTVGDVRNGANAIYSGASEIAMGNNDLSSRTEQQAASLEETAASMEQLTATVKQNA
ENARQASHLALSASETAQKGGKVVDNVVQTMRDIASSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRNLAQRSAQAAREIKSLIEDSVSRVDVGSTLVESAGETMDEIVNAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEM
DRVTQQNASLVEESAAAAAALEEQASRLTQAVAVFRIQQQQQRAREVAAVKTPAAVSSPKAAVADGSDNWETF
>Mature_553_residues
MLKRIKIVTSLLLVLALFGLLQLTSGGLFFNSLKNDKENFTVLQTIRQQQSALNSTWVELLQTRNTLNRAGIRWMMDQSN
IGSGATVAELMQGATNALKLTEKNWAQYESLPRDPRQSEAAFLEIKRTYDIYHGALAELIQLLGAGKINEFFDQPTQSYQ
DAFEKQYMAYMQQNDRLYDIAVEDNNSSYNQAMWVLVSVLIAVLVVIIAVWFGIKLSLIAPMNRLIESIRHIASGDLVKR
IDVEGSNEMGQLADNLRHMQSELVRTVGDVRNGANAIYSGASEIAMGNNDLSSRTEQQAASLEETAASMEQLTATVKQNA
ENARQASHLALSASETAQKGGKVVDNVVQTMRDIASSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRNLAQRSAQAAREIKSLIEDSVSRVDVGSTLVESAGETMDEIVNAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEM
DRVTQQNASLVEESAAAAAALEEQASRLTQAVAVFRIQQQQQRAREVAAVKTPAAVSSPKAAVADGSDNWETF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=553, Percent_Identity=86.4376130198915, Blast_Score=924, Evalue=0.0,
Organism=Escherichia coli, GI1788195, Length=558, Percent_Identity=58.7813620071685, Blast_Score=575, Evalue=1e-165,
Organism=Escherichia coli, GI1788194, Length=522, Percent_Identity=46.7432950191571, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1787690, Length=434, Percent_Identity=48.1566820276498, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1789453, Length=325, Percent_Identity=41.5384615384615, Blast_Score=226, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 60059; Mature: 60059

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50885 HAMP ; PS00538 CHEMOTAXIS_TRANSDUC_1 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRIKIVTSLLLVLALFGLLQLTSGGLFFNSLKNDKENFTVLQTIRQQQSALNSTWVEL
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LQTRNTLNRAGIRWMMDQSNIGSGATVAELMQGATNALKLTEKNWAQYESLPRDPRQSEA
HHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHH
AFLEIKRTYDIYHGALAELIQLLGAGKINEFFDQPTQSYQDAFEKQYMAYMQQNDRLYDI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEE
AVEDNNSSYNQAMWVLVSVLIAVLVVIIAVWFGIKLSLIAPMNRLIESIRHIASGDLVKR
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEE
IDVEGSNEMGQLADNLRHMQSELVRTVGDVRNGANAIYSGASEIAMGNNDLSSRTEQQAA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHCCCCCCHHHHHHHHHH
SLEETAASMEQLTATVKQNAENARQASHLALSASETAQKGGKVVDNVVQTMRDIASSSQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
IEDSVSRVDVGSTLVESAGETMDEIVNAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHH
DRVTQQNASLVEESAAAAAALEEQASRLTQAVAVFRIQQQQQRAREVAAVKTPAAVSSPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AAVADGSDNWETF
CEECCCCCCCCCC
>Mature Secondary Structure
MLKRIKIVTSLLLVLALFGLLQLTSGGLFFNSLKNDKENFTVLQTIRQQQSALNSTWVEL
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LQTRNTLNRAGIRWMMDQSNIGSGATVAELMQGATNALKLTEKNWAQYESLPRDPRQSEA
HHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHH
AFLEIKRTYDIYHGALAELIQLLGAGKINEFFDQPTQSYQDAFEKQYMAYMQQNDRLYDI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEE
AVEDNNSSYNQAMWVLVSVLIAVLVVIIAVWFGIKLSLIAPMNRLIESIRHIASGDLVKR
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEE
IDVEGSNEMGQLADNLRHMQSELVRTVGDVRNGANAIYSGASEIAMGNNDLSSRTEQQAA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHCCCCCCHHHHHHHHHH
SLEETAASMEQLTATVKQNAENARQASHLALSASETAQKGGKVVDNVVQTMRDIASSSQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
IEDSVSRVDVGSTLVESAGETMDEIVNAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHH
DRVTQQNASLVEESAAAAAALEEQASRLTQAVAVFRIQQQQQRAREVAAVKTPAAVSSPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AAVADGSDNWETF
CEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]