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The map label for this gene is yheS [H]

Identifier: 194737834

GI number: 194737834

Start: 3507746

End: 3509653

Strand: Direct

Name: yheS [H]

Synonym: SeSA_A3655

Alternate gene names: 194737834

Gene position: 3507746-3509653 (Clockwise)

Preceding gene: 194736094

Following gene: 194738184

Centisome position: 74.49

GC content: 57.55

Gene sequence:

>1908_bases
ATGATTGTTTTCTCCTCGTTACAAATTCGTCGCGGCGTGCGCGTCCTACTGGACAATGCCTCGGCTACCATTAATCCAGG
CCAGAAAGTCGGCCTGGTGGGTAAAAACGGCTGCGGTAAATCTACCCTGCTGGCATTGCTAAAAAATGAAATCAGCGCCG
ATGCCGGGAGTTTTACCCTGCCCGGAACCTGGCAATTAGCGTGGGTGAATCAGGAAACACCTGCGTTGCCTCAGCCAGCG
ATTGAGTATGTCATTGATAGCGACCGTGAATACCGGCAGCTGGAGGCGCAGCTTAACGACGCCAACGAACGTAACGACGG
ACATGCTATCGCCTCCATACACGGTAAGCTGGACGCCATCGACGCATGGACCGTTCGCTCGCGCGCCGCCAGCCTGCTAC
ACGGCCTCGGCTTCTCTAACGATCAGCTGGAACGTCCGGTCAGCGACTTTTCCGGCGGCTGGCGGATGCGCCTTAACCTG
GCCCAGGCGCTGATTTGCCGTTCCGATTTACTGCTGCTCGACGAACCGACCAACCACCTCGATCTGGATGCCGTTATCTG
GCTGGAAAAATGGCTGAAGAGCTATCCGGGCACCCTGATTCTGATCTCCCACGATCGCGATTTTCTTGACCCGATAGTGG
ATAAAATTATCCATATCGAACAGCAGACTCTGTTCGAGTACACCGGCAACTACAGCGCGTTTGAAGTTCAGCGCGCCACG
CGCCTGGCGCAACAGCAGGCGATGTATGAGAGCCAGCAGGAGCGTGTGGCGCATCTGCAAAGCTACATCGACCGTTTCCG
CGCCAAAGCGACCAAGGCCAAGCAGGCACAAAGCCGTATCAAGATGCTGGAGCGTATGGAGCTGATTGCGCCAGCTCATG
TCGACAACCCGTTCCATTTCAGCTTCCGCGCGCCGGAAAGCCTGCCGAACCCGCTGCTGAAGATGGAAAAAGTCAGCGCA
GGTTATGGCGATCGCATCATTCTGGAATCCATCAAGCTGAACCTGGTGCCCGGCTCACGTATCGGCCTGCTGGGCCGCAA
CGGTGCGGGGAAATCGACGCTGATCAAGCTGCTGGCGGGCGAACTGGAACCGTTGCACGGTGAAATTGGCCTCGCCAAAG
GCATTAAGCTCGGCTACTTCGCCCAGCACCAACTGGAGTTCCTGCGCGCCGATGAATCCCCGTTGCAGCATATGGCGCGT
CTGGCGCCGCAGGAACTGGAGCAGAAGCTGCGCGACTATCTCGGCGGCTTCGGTTTCCAGGGCGACAAAGTAACGGAAGA
GACGCAACGTTTCTCCGGCGGCGAGAAAGCGCGCTTGGTACTGGCGCTGATCGTCTGGCAGCGTCCAAATCTGCTGCTGC
TCGATGAACCGACCAACCACCTGGATCTCGACATGCGTCAGGCGCTCACCGAAGCGCTGATTGATTTTGAAGGCGCATTG
GTCGTCGTGTCGCACGACCGCCACCTGATTCGCTCCACCACTGACGACCTCTATCTGGTGCACGACAAAAAGGTCGAACC
GTTCGACGGCGACCTGGAAGATTATCAGCAGTGGCTGAGCGACGTGCAGAAGCAGGAAAACCAGGCCGACGACGCGCCGA
AGGAAAACAACGCCAACAGCGCCCAGTCACGCAAAGATCAGAAGCGTCGCGAAGCCGAGCTACGTACTCTGACGCAGCCG
CTGCGTAAAGAGATTACCCGTCTGGAAAAAGAGATGGAAAAGCTCAACGCCCAACTGGCGCAGGCGGAAGAGAAACTCGG
CGACAGCAGCCTGTATGACCCCAGCCGTAAAGCGGAGATGACCGAGTGTCTGCAACTGCAGGCCAGCGCCAAATCCGGGC
TGGAAGAGTGTGAAATGGCATGGCTTGAGGCGCAGGAGCAGCTTGAGCAAATGATGCAGAACGACTAA

Upstream 100 bases:

>100_bases
GTTGTTGTTTTGAGCTACCATTGCGCTCCAGCGCGGCGGTACGCCCGAATATTACATTATCATAATGATAAATTAACATA
GTCTGAACATACGGCGCCTT

Downstream 100 bases:

>100_bases
CGCGCGGGGCGGACGATGAACCTGTCAATCACCGATGACATTACCTTCCGCAAGCTCACCATCTTCATGATGTTTGTGGA
GAAAGGTAACATCGCCCGCA

Product: putative ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MIVFSSLQIRRGVRVLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNEISADAGSFTLPGTWQLAWVNQETPALPQPA
IEYVIDSDREYRQLEAQLNDANERNDGHAIASIHGKLDAIDAWTVRSRAASLLHGLGFSNDQLERPVSDFSGGWRMRLNL
AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYPGTLILISHDRDFLDPIVDKIIHIEQQTLFEYTGNYSAFEVQRAT
RLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQAQSRIKMLERMELIAPAHVDNPFHFSFRAPESLPNPLLKMEKVSA
GYGDRIILESIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELEPLHGEIGLAKGIKLGYFAQHQLEFLRADESPLQHMAR
LAPQELEQKLRDYLGGFGFQGDKVTEETQRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
VVVSHDRHLIRSTTDDLYLVHDKKVEPFDGDLEDYQQWLSDVQKQENQADDAPKENNANSAQSRKDQKRREAELRTLTQP
LRKEITRLEKEMEKLNAQLAQAEEKLGDSSLYDPSRKAEMTECLQLQASAKSGLEECEMAWLEAQEQLEQMMQND

Sequences:

>Translated_635_residues
MIVFSSLQIRRGVRVLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNEISADAGSFTLPGTWQLAWVNQETPALPQPA
IEYVIDSDREYRQLEAQLNDANERNDGHAIASIHGKLDAIDAWTVRSRAASLLHGLGFSNDQLERPVSDFSGGWRMRLNL
AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYPGTLILISHDRDFLDPIVDKIIHIEQQTLFEYTGNYSAFEVQRAT
RLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQAQSRIKMLERMELIAPAHVDNPFHFSFRAPESLPNPLLKMEKVSA
GYGDRIILESIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELEPLHGEIGLAKGIKLGYFAQHQLEFLRADESPLQHMAR
LAPQELEQKLRDYLGGFGFQGDKVTEETQRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
VVVSHDRHLIRSTTDDLYLVHDKKVEPFDGDLEDYQQWLSDVQKQENQADDAPKENNANSAQSRKDQKRREAELRTLTQP
LRKEITRLEKEMEKLNAQLAQAEEKLGDSSLYDPSRKAEMTECLQLQASAKSGLEECEMAWLEAQEQLEQMMQND
>Mature_635_residues
MIVFSSLQIRRGVRVLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNEISADAGSFTLPGTWQLAWVNQETPALPQPA
IEYVIDSDREYRQLEAQLNDANERNDGHAIASIHGKLDAIDAWTVRSRAASLLHGLGFSNDQLERPVSDFSGGWRMRLNL
AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYPGTLILISHDRDFLDPIVDKIIHIEQQTLFEYTGNYSAFEVQRAT
RLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQAQSRIKMLERMELIAPAHVDNPFHFSFRAPESLPNPLLKMEKVSA
GYGDRIILESIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELEPLHGEIGLAKGIKLGYFAQHQLEFLRADESPLQHMAR
LAPQELEQKLRDYLGGFGFQGDKVTEETQRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
VVVSHDRHLIRSTTDDLYLVHDKKVEPFDGDLEDYQQWLSDVQKQENQADDAPKENNANSAQSRKDQKRREAELRTLTQP
LRKEITRLEKEMEKLNAQLAQAEEKLGDSSLYDPSRKAEMTECLQLQASAKSGLEECEMAWLEAQEQLEQMMQND

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=538, Percent_Identity=37.7323420074349, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI27881506, Length=513, Percent_Identity=36.4522417153996, Blast_Score=315, Evalue=1e-85,
Organism=Homo sapiens, GI10947137, Length=513, Percent_Identity=36.4522417153996, Blast_Score=314, Evalue=1e-85,
Organism=Homo sapiens, GI10947135, Length=525, Percent_Identity=35.4285714285714, Blast_Score=276, Evalue=3e-74,
Organism=Homo sapiens, GI69354671, Length=525, Percent_Identity=35.4285714285714, Blast_Score=276, Evalue=3e-74,
Organism=Escherichia coli, GI1789751, Length=632, Percent_Identity=93.3544303797468, Blast_Score=1217, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=529, Percent_Identity=33.0812854442344, Blast_Score=298, Evalue=9e-82,
Organism=Escherichia coli, GI2367384, Length=531, Percent_Identity=30.1318267419962, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1787182, Length=627, Percent_Identity=28.7081339712919, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1788165, Length=191, Percent_Identity=34.5549738219895, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790190, Length=528, Percent_Identity=23.2954545454545, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI87081782, Length=502, Percent_Identity=24.9003984063745, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081791, Length=204, Percent_Identity=27.9411764705882, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787164, Length=216, Percent_Identity=28.2407407407407, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787758, Length=205, Percent_Identity=25.3658536585366, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788506, Length=230, Percent_Identity=27.8260869565217, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI48994997, Length=221, Percent_Identity=25.3393665158371, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1789586, Length=218, Percent_Identity=27.9816513761468, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787500, Length=223, Percent_Identity=27.3542600896861, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI48994883, Length=233, Percent_Identity=25.3218884120172, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI87081709, Length=213, Percent_Identity=21.5962441314554, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=530, Percent_Identity=38.1132075471698, Blast_Score=360, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17555318, Length=524, Percent_Identity=35.3053435114504, Blast_Score=325, Evalue=6e-89,
Organism=Caenorhabditis elegans, GI17559834, Length=547, Percent_Identity=34.3692870201097, Blast_Score=314, Evalue=7e-86,
Organism=Caenorhabditis elegans, GI71996809, Length=204, Percent_Identity=31.8627450980392, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193211017, Length=184, Percent_Identity=32.6086956521739, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193211015, Length=184, Percent_Identity=32.6086956521739, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17556528, Length=295, Percent_Identity=23.0508474576271, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=542, Percent_Identity=35.7933579335793, Blast_Score=345, Evalue=1e-95,
Organism=Saccharomyces cerevisiae, GI6320874, Length=534, Percent_Identity=35.2059925093633, Blast_Score=317, Evalue=3e-87,
Organism=Saccharomyces cerevisiae, GI6325030, Length=438, Percent_Identity=28.9954337899543, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6324314, Length=390, Percent_Identity=27.6923076923077, Blast_Score=145, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6323278, Length=391, Percent_Identity=27.6214833759591, Blast_Score=140, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24666836, Length=517, Percent_Identity=38.2978723404255, Blast_Score=377, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24642252, Length=523, Percent_Identity=37.8585086042065, Blast_Score=351, Evalue=8e-97,
Organism=Drosophila melanogaster, GI18859989, Length=523, Percent_Identity=37.8585086042065, Blast_Score=351, Evalue=8e-97,
Organism=Drosophila melanogaster, GI24641342, Length=532, Percent_Identity=35.7142857142857, Blast_Score=311, Evalue=7e-85,
Organism=Drosophila melanogaster, GI24661270, Length=191, Percent_Identity=28.7958115183246, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355589, Length=191, Percent_Identity=28.7958115183246, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007184, Length=163, Percent_Identity=31.2883435582822, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221500365, Length=163, Percent_Identity=31.2883435582822, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71677; Mature: 71677

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVFSSLQIRRGVRVLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNEISADAGSFTL
CEEECCHHHHCCCEEEEECCCCEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEC
PGTWQLAWVNQETPALPQPAIEYVIDSDREYRQLEAQLNDANERNDGHAIASIHGKLDAI
CCCEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCH
DAWTVRSRAASLLHGLGFSNDQLERPVSDFSGGWRMRLNLAQALICRSDLLLLDEPTNHL
HHHHHHHHHHHHHHHCCCCCHHHHCCHHHCCCCEEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVIWLEKWLKSYPGTLILISHDRDFLDPIVDKIIHIEQQTLFEYTGNYSAFEVQRAT
CHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQAQSRIKMLERMELIAPAHVDNPFHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
SFRAPESLPNPLLKMEKVSAGYGDRIILESIKLNLVPGSRIGLLGRNGAGKSTLIKLLAG
EEECCCCCCCHHHHHHHHCCCCCCEEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHH
ELEPLHGEIGLAKGIKLGYFAQHQLEFLRADESPLQHMARLAPQELEQKLRDYLGGFGFQ
CCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHCCCCCC
GDKVTEETQRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
CCCHHHHHHHCCCCCHHHHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VVVSHDRHLIRSTTDDLYLVHDKKVEPFDGDLEDYQQWLSDVQKQENQADDAPKENNANS
EEEECCCHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
AQSRKDQKRREAELRTLTQPLRKEITRLEKEMEKLNAQLAQAEEKLGDSSLYDPSRKAEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
TECLQLQASAKSGLEECEMAWLEAQEQLEQMMQND
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIVFSSLQIRRGVRVLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNEISADAGSFTL
CEEECCHHHHCCCEEEEECCCCEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEC
PGTWQLAWVNQETPALPQPAIEYVIDSDREYRQLEAQLNDANERNDGHAIASIHGKLDAI
CCCEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCH
DAWTVRSRAASLLHGLGFSNDQLERPVSDFSGGWRMRLNLAQALICRSDLLLLDEPTNHL
HHHHHHHHHHHHHHHCCCCCHHHHCCHHHCCCCEEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVIWLEKWLKSYPGTLILISHDRDFLDPIVDKIIHIEQQTLFEYTGNYSAFEVQRAT
CHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQAQSRIKMLERMELIAPAHVDNPFHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
SFRAPESLPNPLLKMEKVSAGYGDRIILESIKLNLVPGSRIGLLGRNGAGKSTLIKLLAG
EEECCCCCCCHHHHHHHHCCCCCCEEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHH
ELEPLHGEIGLAKGIKLGYFAQHQLEFLRADESPLQHMARLAPQELEQKLRDYLGGFGFQ
CCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHCCCCCC
GDKVTEETQRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
CCCHHHHHHHCCCCCHHHHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VVVSHDRHLIRSTTDDLYLVHDKKVEPFDGDLEDYQQWLSDVQKQENQADDAPKENNANS
EEEECCCHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
AQSRKDQKRREAELRTLTQPLRKEITRLEKEMEKLNAQLAQAEEKLGDSSLYDPSRKAEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
TECLQLQASAKSGLEECEMAWLEAQEQLEQMMQND
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]