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The map label for this gene is hdfR [H]

Identifier: 194737743

GI number: 194737743

Start: 3981582

End: 3982418

Strand: Reverse

Name: hdfR [H]

Synonym: SeSA_A4108

Alternate gene names: 194737743

Gene position: 3982418-3981582 (Counterclockwise)

Preceding gene: 194734470

Following gene: 194738253

Centisome position: 84.57

GC content: 51.37

Gene sequence:

>837_bases
GTGGATACGGAATTGTTAAAAACTTTCCTGGAAGTTAGCCGGACACGCCATTTCGGGCGGGCCGCAGAAGCACTTTACCT
GACGCAATCCGCGGTGAGCTTTCGTATCAGGCAACTGGAGAATCAACTGGGCGTAAACCTTTTTACGCGGCACAGAAACA
ATATCCGTTTAACCACGGCTGGCGAAAAACTTTTACCGTATGCGGAAACGCTGATGAATACGTGGCAGGCGGCACGTAAA
GAGGTGGCGCATACCTCACGCCATAACGAGTTTTCCATCGGCGCCAGCGCGTCTTTATGGGAGTGTATGCTTAACGCCTG
GCTGGGTCGACTGTACCAACTACAGGAGCCGCAAAGCGGCCTGCAATTCGAAGCCAGAATCGCTCAACGGCAATCGCTTG
TGAAGCAACTTCATGAACGCCAGCTTGATCTCCTCATTACTACCGAAGCGCCCAAAATGGATGAGTTCAGCAGTCAGCTG
TTAGGGCACTTCACTTTGGCGTTATATTGCAGCAGCCCTGCCCGTAAGAAATCAGAACTCAATTATCTGCGGCTGGAGTG
GGGACCAGACTTCCAACAGCATGAAACAGGGCTGATCGCAGCAGATGAAGTGCCGGTATTAACAACCAGCTCAGCCGAAC
TCGCCCGACAGCAGCTTAGCGCATTAAATGGCTGTAGCTGGCTTCCTGTAAACTGGGTAAATGAAAAGGGCGGATTACAT
ACCGTTGCCGACAGCGCAACGCTTTCACGGCCGCTATACGCCATTTGGCTGCAAAATAGCGATAAATACTCGCTGATCTG
CGATCTGTTAAAAACGGATGTGCTGGATGACCAATGA

Upstream 100 bases:

>100_bases
TTTGTCTGAGCTATTTATGGCGCGGAGTATTAGTTACGCTTGACAGAGTGTAAAACAAAACATTTAAATCATAACGACAA
ATAATTTTGTGGAGAGCACA

Downstream 100 bases:

>100_bases
AAATGATGAAAAGAAAAAGAAGGGAACTTACGATTACCTGACCAGGTAATCAGGTAATTTCAGGCAAAAAAAAATCCTTA
GCAGATGCTAAGGATTATTT

Product: transcriptional regulator HdfR

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTAGEKLLPYAETLMNTWQAARK
EVAHTSRHNEFSIGASASLWECMLNAWLGRLYQLQEPQSGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
LGHFTLALYCSSPARKKSELNYLRLEWGPDFQQHETGLIAADEVPVLTTSSAELARQQLSALNGCSWLPVNWVNEKGGLH
TVADSATLSRPLYAIWLQNSDKYSLICDLLKTDVLDDQ

Sequences:

>Translated_278_residues
MDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTAGEKLLPYAETLMNTWQAARK
EVAHTSRHNEFSIGASASLWECMLNAWLGRLYQLQEPQSGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
LGHFTLALYCSSPARKKSELNYLRLEWGPDFQQHETGLIAADEVPVLTTSSAELARQQLSALNGCSWLPVNWVNEKGGLH
TVADSATLSRPLYAIWLQNSDKYSLICDLLKTDVLDDQ
>Mature_278_residues
MDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTAGEKLLPYAETLMNTWQAARK
EVAHTSRHNEFSIGASASLWECMLNAWLGRLYQLQEPQSGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
LGHFTLALYCSSPARKKSELNYLRLEWGPDFQQHETGLIAADEVPVLTTSSAELARQQLSALNGCSWLPVNWVNEKGGLH
TVADSATLSRPLYAIWLQNSDKYSLICDLLKTDVLDDQ

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=277, Percent_Identity=86.6425992779783, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI1787601, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788626, Length=151, Percent_Identity=31.1258278145695, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367136, Length=64, Percent_Identity=48.4375, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790208, Length=68, Percent_Identity=45.5882352941176, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31618; Mature: 31618

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEC
GEKLLPYAETLMNTWQAARKEVAHTSRHNEFSIGASASLWECMLNAWLGRLYQLQEPQSG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
LQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQLLGHFTLALYCSSPARKKSEL
CHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCC
NYLRLEWGPDFQQHETGLIAADEVPVLTTSSAELARQQLSALNGCSWLPVNWVNEKGGLH
CEEEEECCCCHHHHCCCEEEECCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
TVADSATLSRPLYAIWLQNSDKYSLICDLLKTDVLDDQ
EEECCHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEC
GEKLLPYAETLMNTWQAARKEVAHTSRHNEFSIGASASLWECMLNAWLGRLYQLQEPQSG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
LQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQLLGHFTLALYCSSPARKKSEL
CHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCC
NYLRLEWGPDFQQHETGLIAADEVPVLTTSSAELARQQLSALNGCSWLPVNWVNEKGGLH
CEEEEECCCCHHHHCCCEEEECCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
TVADSATLSRPLYAIWLQNSDKYSLICDLLKTDVLDDQ
EEECCHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA