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The map label for this gene is sgbH [H]

Identifier: 194737692

GI number: 194737692

Start: 3740650

End: 3741300

Strand: Direct

Name: sgbH [H]

Synonym: SeSA_A3873

Alternate gene names: 194737692

Gene position: 3740650-3741300 (Clockwise)

Preceding gene: 194734656

Following gene: 194737478

Centisome position: 79.43

GC content: 61.44

Gene sequence:

>651_bases
ATGAGCCGACCATTACTGCAACTGGCGCTCGACCACACCAGTCTGGAAGCAGCCCAACGCGATGTCGCCCTACTACAGGA
TCATGTCGATATCGTTGAGGCCGGAACCATCCTTTGTTTAACCGAAGGCCTTAGCGCGGTGAAAGCCCTGCGAGCGCAGT
GCCCGGAAAAAATCATCGTCGCCGACTGGAAAGTGGCCGATGCCGGTGAAACCCTGGCGCAGCAGGCTTTTGGCGCTGGC
GCCAACTGGATGACCATCATCTGCGCCGCGCCGCTCGCCACGGTCGAGAAAGGCCATGCCGTCGCGCAATCCTGCGGCGG
TGAAATCCAAATGGAACTGTTCGGCAACTGGACGCTGGACGACGCCCGAGACTGGTATCGCGTCGGGGTTCGCCAGGCGA
TTTACCACCGCGGACGCGATGCGCAGGCCAGCGGGCAGCAGTGGGGAGAGGCGGACCTGACGCGTATGAAAGCGTTGTCC
GACATCGGCCTTGAGCTGTCAATTACCGGTGGTATTACCCCGGCCGATCTACCGCTGTTCCGCGACATTAACGTTAAGGC
ATTTATCGCCGGACGCGCGCTGGCAGGTGCCGCCCATCCGGCGCAGGTCGCCGCCGAATTCCACGCCCAAATTGACGCCA
TCTGGGGATAA

Upstream 100 bases:

>100_bases
ACATGACCGCACACGCCCTCTACCAGCGCAAATACCGCCAATACCAGGATTTGATTGAAGCACTACAGGGCTATCACGCC
CGTATTAAGGAGCACGCATT

Downstream 100 bases:

>100_bases
CAACATGCGTAATCATCCATTAGGTATTTACGAGAAAGCACTGGCGAAAGATCTCAGTTGGCCGGAGCGGTTGGTGCTGG
CAAAAAGCTGCGGTTTTGAT

Product: 3-keto-L-gulonate-6-phosphate decarboxylase

Products: NA

Alternate protein names: KGPDC; 3-dehydro-L-gulonate-6-phosphate decarboxylase [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSRPLLQLALDHTSLEAAQRDVALLQDHVDIVEAGTILCLTEGLSAVKALRAQCPEKIIVADWKVADAGETLAQQAFGAG
ANWMTIICAAPLATVEKGHAVAQSCGGEIQMELFGNWTLDDARDWYRVGVRQAIYHRGRDAQASGQQWGEADLTRMKALS
DIGLELSITGGITPADLPLFRDINVKAFIAGRALAGAAHPAQVAAEFHAQIDAIWG

Sequences:

>Translated_216_residues
MSRPLLQLALDHTSLEAAQRDVALLQDHVDIVEAGTILCLTEGLSAVKALRAQCPEKIIVADWKVADAGETLAQQAFGAG
ANWMTIICAAPLATVEKGHAVAQSCGGEIQMELFGNWTLDDARDWYRVGVRQAIYHRGRDAQASGQQWGEADLTRMKALS
DIGLELSITGGITPADLPLFRDINVKAFIAGRALAGAAHPAQVAAEFHAQIDAIWG
>Mature_215_residues
SRPLLQLALDHTSLEAAQRDVALLQDHVDIVEAGTILCLTEGLSAVKALRAQCPEKIIVADWKVADAGETLAQQAFGAGA
NWMTIICAAPLATVEKGHAVAQSCGGEIQMELFGNWTLDDARDWYRVGVRQAIYHRGRDAQASGQQWGEADLTRMKALSD
IGLELSITGGITPADLPLFRDINVKAFIAGRALAGAAHPAQVAAEFHAQIDAIWG

Specific function: Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. May be involved in the utilization of 2,3- diketo-L-gulonate [H]

COG id: COG0269

COG function: function code G; 3-hexulose-6-phosphate synthase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. KGPDC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790006, Length=216, Percent_Identity=91.2037037037037, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1790640, Length=216, Percent_Identity=46.2962962962963, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.85 [H]

Molecular weight: Translated: 23093; Mature: 22961

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPLLQLALDHTSLEAAQRDVALLQDHVDIVEAGTILCLTEGLSAVKALRAQCPEKIIV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHCCCCEEE
ADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAVAQSCGGEIQMELFGNWTLD
ECCEECCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCCCCH
DARDWYRVGVRQAIYHRGRDAQASGQQWGEADLTRMKALSDIGLELSITGGITPADLPLF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCEE
RDINVKAFIAGRALAGAAHPAQVAAEFHAQIDAIWG
ECCCEEEEEECCHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRPLLQLALDHTSLEAAQRDVALLQDHVDIVEAGTILCLTEGLSAVKALRAQCPEKIIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHCCCCEEE
ADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAVAQSCGGEIQMELFGNWTLD
ECCEECCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCCCCH
DARDWYRVGVRQAIYHRGRDAQASGQQWGEADLTRMKALSDIGLELSITGGITPADLPLF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCEE
RDINVKAFIAGRALAGAAHPAQVAAEFHAQIDAIWG
ECCCEEEEEECCHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 9274005; 11741871 [H]