Click here to switch to the map view.

The map label for this gene is sopD2 [H]

Identifier: 194737629

GI number: 194737629

Start: 1062802

End: 1063530

Strand: Direct

Name: sopD2 [H]

Synonym: SeSA_A1085

Alternate gene names: 194737629

Gene position: 1062802-1063530 (Clockwise)

Preceding gene: 194734865

Following gene: 194735109

Centisome position: 22.57

GC content: 32.1

Gene sequence:

>729_bases
ATGGAGAAGATATATGCCTTTGCACAATTAAAACAATATGCTAATCCATCTCAACAAGACCGCTTTGTTATGCGTTTTGA
TGTGAGTCAGACACAAGTTTCATTTGAGATTGATGGCAAGGTTATTGATAAATGTAATTTGCATCGTATCCTCAATGTTT
CAGAAAACTGTATTTTTAAAGTGATGGAAGAAGATGAAGAAGAGTTGTTTTTTAAAGTATGTATTAAGTATGGAGAAAAA
ATTGCTTGCTATCCAGAATTATTAGAAAACTTTGCTTTTAAACTTAGGCAGGAAGTTAATGAAGATGATGAAATTAAGGA
TGAAGTTTATAAGCTTATGCGATCTGGAGAAGATCGAAAAATGGCATGTGTTGAATGGAATGGTACGCTTACTGAGGATG
AGATGGATAAACTACGCTGTCTCCAAATGGGGTCTTTTGAGATTTCTACCCAATTTTGTAAAATAGGTTACTGGGAATTA
GAGGGAGAAGTCCTGTTTGATATGTTTCATCCAACACTTATCTATCTGCTACATGGATATATGCCGTCATTGTCATGTGA
TTTTACAGAAGCTAACACCATGCTGTTTTCTGATGTATTAAATAAGGATTATGATGATTATCAAAATAATAAAAGAGAAA
TTGATGCTATTCTGAGAAGAATATATAGATCACATAATAACACTTTATTTATAAGTAAAAATTCTGGTTGTCGAAATATG
CTTTTATAA

Upstream 100 bases:

>100_bases
CAGAACACACAAAAAAAGAGAGGTGCTGGAGGTATTATATACACTCATCCATGGATGTGAACGTGAAAATCAAGCTGACC
TTAATGTTGATACAGTCGGC

Downstream 100 bases:

>100_bases
AAATTAAAAAGGCCCCACTGACATGGAGCCTTTTTTGTACGCTTTTTATAGCGTAATTTCAGTCAAACCCATTACATGGT
CTGCGTGAAGGTACGAGTAA

Product: hypothetical protein

Products: NA

Alternate protein names: Salmonella outer protein D 2 [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MEKIYAFAQLKQYANPSQQDRFVMRFDVSQTQVSFEIDGKVIDKCNLHRILNVSENCIFKVMEEDEEELFFKVCIKYGEK
IACYPELLENFAFKLRQEVNEDDEIKDEVYKLMRSGEDRKMACVEWNGTLTEDEMDKLRCLQMGSFEISTQFCKIGYWEL
EGEVLFDMFHPTLIYLLHGYMPSLSCDFTEANTMLFSDVLNKDYDDYQNNKREIDAILRRIYRSHNNTLFISKNSGCRNM
LL

Sequences:

>Translated_242_residues
MEKIYAFAQLKQYANPSQQDRFVMRFDVSQTQVSFEIDGKVIDKCNLHRILNVSENCIFKVMEEDEEELFFKVCIKYGEK
IACYPELLENFAFKLRQEVNEDDEIKDEVYKLMRSGEDRKMACVEWNGTLTEDEMDKLRCLQMGSFEISTQFCKIGYWEL
EGEVLFDMFHPTLIYLLHGYMPSLSCDFTEANTMLFSDVLNKDYDDYQNNKREIDAILRRIYRSHNNTLFISKNSGCRNM
LL
>Mature_242_residues
MEKIYAFAQLKQYANPSQQDRFVMRFDVSQTQVSFEIDGKVIDKCNLHRILNVSENCIFKVMEEDEEELFFKVCIKYGEK
IACYPELLENFAFKLRQEVNEDDEIKDEVYKLMRSGEDRKMACVEWNGTLTEDEMDKLRCLQMGSFEISTQFCKIGYWEL
EGEVLFDMFHPTLIYLLHGYMPSLSCDFTEANTMLFSDVLNKDYDDYQNNKREIDAILRRIYRSHNNTLFISKNSGCRNM
LL

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Contributes to the formation of Salmonella-induced filaments (Sifs) in infected epithelial cells and to replication in macrophages [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane. Note=Secreted via type III secretion system 2 (SPI-2 TTSS), and delivered into the host cell. Membrane-associated. Localizes to the Salmonella- containing vacuole (SCV) in infected cells and to late endocytic compartments in

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sopD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022747
- ProDom:   PD040905 [H]

Pfam domain/function: PF11047 SopD [H]

EC number: NA

Molecular weight: Translated: 28707; Mature: 28707

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIYAFAQLKQYANPSQQDRFVMRFDVSQTQVSFEIDGKVIDKCNLHRILNVSENCIFK
CCHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEECCEEECCCCHHHHHCCCHHHHHH
VMEEDEEELFFKVCIKYGEKIACYPELLENFAFKLRQEVNEDDEIKDEVYKLMRSGEDRK
HHHCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCE
MACVEWNGTLTEDEMDKLRCLQMGSFEISTQFCKIGYWELEGEVLFDMFHPTLIYLLHGY
EEEEEECCCCCHHHHHHHHHHHCCCEEEEHHHHCCEEEEECCHHHHHHHHHHHHHHHHHC
MPSLSCDFTEANTMLFSDVLNKDYDDYQNNKREIDAILRRIYRSHNNTLFISKNSGCRNM
CCCCCCCCCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
LL
CC
>Mature Secondary Structure
MEKIYAFAQLKQYANPSQQDRFVMRFDVSQTQVSFEIDGKVIDKCNLHRILNVSENCIFK
CCHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEECCEEECCCCHHHHHCCCHHHHHH
VMEEDEEELFFKVCIKYGEKIACYPELLENFAFKLRQEVNEDDEIKDEVYKLMRSGEDRK
HHHCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCE
MACVEWNGTLTEDEMDKLRCLQMGSFEISTQFCKIGYWELEGEVLFDMFHPTLIYLLHGY
EEEEEECCCCCHHHHHHHHHHHCCCEEEEHHHHCCEEEEECCHHHHHHHHHHHHHHHHHC
MPSLSCDFTEANTMLFSDVLNKDYDDYQNNKREIDAILRRIYRSHNNTLFISKNSGCRNM
CCCCCCCCCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
LL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]