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The map label for this gene is opuCB [H]

Identifier: 194737451

GI number: 194737451

Start: 1537133

End: 1537780

Strand: Reverse

Name: opuCB [H]

Synonym: SeSA_A1594

Alternate gene names: 194737451

Gene position: 1537780-1537133 (Counterclockwise)

Preceding gene: 194737639

Following gene: 194734404

Centisome position: 32.66

GC content: 54.94

Gene sequence:

>648_bases
ATGGATACGATACATTATATGCTGGATAACGCAGGCTATCTCGCCAGCCTTACCTTTCAGCATCTCTGGCTGGTCGCGCT
GGCCGTCGGTCTGGCGATTATCATCGGCGTACCGTTAGGCGTTTTGATTGTACGCCACAAATGGCTGGCAACGCCGGTAT
TGGGCGCCGCCACGCTACTTCTTACCATTCCGTCTATCGCGCTGTTTGGATTAATGATCCCGCTCTTTTCGCTGATCGGG
CATGGTATTGGCGTTCTGCCCGCCGTGACGGCCGTTTTTCTCTACTCTTTACTGCCGATTGTCCGTAATACCCATACTGC
GCTTGATAGTTTGCCGCCCGGTCTGCGTGAAGCGGGACGCGGCATCGGTATGACTTTCTGGCAACGGCTGCGCTGGGTCG
AAATCCCAATGGCCCTACCGGTTATTTTCGGGGGTATCCGCACCGCGGTAGTGATGAATATCGGCGTGATGGCGATTGCC
GCGGTGATCGGTGCCGGCGGTCTGGGGCTGCTACTGTTAAACGGCATTAGCGGCAGCGATATTCGCATGTTAATTGCCGG
CGCGCTGATGATCTGTCTACTGGCAATTGTACTTGACTGGCTGTTGCATCGTCTGCAAGTCGTACTGACACCTAAGGGGA
TACGATAA

Upstream 100 bases:

>100_bases
GATATCGACCCTAAACGCCCAGGTCGATATCGAGCATCGCACGCCGCAACAGGTAGCCCATCAATTTTTGCAGGACAAAG
GTCTGCTGTAAGGAGCGCCT

Downstream 100 bases:

>100_bases
TGATAAAACTGGAAAATCTCACCAAACAATTTGTACAGAAAAAGGGTCAGCCGCTAAAAGCCGTCGACAACGTCAACCTG
AACGTGCCGGAAGGCGAAAT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MDTIHYMLDNAGYLASLTFQHLWLVALAVGLAIIIGVPLGVLIVRHKWLATPVLGAATLLLTIPSIALFGLMIPLFSLIG
HGIGVLPAVTAVFLYSLLPIVRNTHTALDSLPPGLREAGRGIGMTFWQRLRWVEIPMALPVIFGGIRTAVVMNIGVMAIA
AVIGAGGLGLLLLNGISGSDIRMLIAGALMICLLAIVLDWLLHRLQVVLTPKGIR

Sequences:

>Translated_215_residues
MDTIHYMLDNAGYLASLTFQHLWLVALAVGLAIIIGVPLGVLIVRHKWLATPVLGAATLLLTIPSIALFGLMIPLFSLIG
HGIGVLPAVTAVFLYSLLPIVRNTHTALDSLPPGLREAGRGIGMTFWQRLRWVEIPMALPVIFGGIRTAVVMNIGVMAIA
AVIGAGGLGLLLLNGISGSDIRMLIAGALMICLLAIVLDWLLHRLQVVLTPKGIR
>Mature_215_residues
MDTIHYMLDNAGYLASLTFQHLWLVALAVGLAIIIGVPLGVLIVRHKWLATPVLGAATLLLTIPSIALFGLMIPLFSLIG
HGIGVLPAVTAVFLYSLLPIVRNTHTALDSLPPGLREAGRGIGMTFWQRLRWVEIPMALPVIFGGIRTAVVMNIGVMAIA
AVIGAGGLGLLLLNGISGSDIRMLIAGALMICLLAIVLDWLLHRLQVVLTPKGIR

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=195, Percent_Identity=36.9230769230769, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1788451, Length=204, Percent_Identity=36.7647058823529, Blast_Score=107, Evalue=4e-25,
Organism=Escherichia coli, GI1789033, Length=173, Percent_Identity=32.3699421965318, Blast_Score=81, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 22883; Mature: 22883

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTIHYMLDNAGYLASLTFQHLWLVALAVGLAIIIGVPLGVLIVRHKWLATPVLGAATLL
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTIPSIALFGLMIPLFSLIGHGIGVLPAVTAVFLYSLLPIVRNTHTALDSLPPGLREAGR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCC
GIGMTFWQRLRWVEIPMALPVIFGGIRTAVVMNIGVMAIAAVIGAGGLGLLLLNGISGSD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCH
IRMLIAGALMICLLAIVLDWLLHRLQVVLTPKGIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDTIHYMLDNAGYLASLTFQHLWLVALAVGLAIIIGVPLGVLIVRHKWLATPVLGAATLL
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTIPSIALFGLMIPLFSLIGHGIGVLPAVTAVFLYSLLPIVRNTHTALDSLPPGLREAGR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCC
GIGMTFWQRLRWVEIPMALPVIFGGIRTAVVMNIGVMAIAAVIGAGGLGLLLLNGISGSD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCH
IRMLIAGALMICLLAIVLDWLLHRLQVVLTPKGIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]