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The map label for this gene is murB [H]

Identifier: 194737386

GI number: 194737386

Start: 4224000

End: 4225028

Strand: Direct

Name: murB [H]

Synonym: SeSA_A4348

Alternate gene names: 194737386

Gene position: 4224000-4225028 (Clockwise)

Preceding gene: 194738097

Following gene: 194734870

Centisome position: 89.7

GC content: 53.35

Gene sequence:

>1029_bases
ATGACCCACTCCCTAAAACCCTGGAATACCTTCGGCATTGATCATTGTGCAAAGCACATCGTATGCGCTGAAAACGAACA
ACAACTACTGAGCGCCTGGCAGCAAGCAACTCGTGAGGGACTGCCGGTTATGATCCTGGGTGAAGGAAGCAATGTCCTGT
TTCTGGAGAATTACGCCGGCACCGTGATCCTTAACCGCCTGAAAGGCATTGAGGTCAATGAAACCGCGGACGCCTGGCAC
CTACACGTCGGCGCAGGCGAAAACTGGCATCAGCTGGTTCGCTACGCGCTGGACAACAACATGCCCGGCCTGGAGAATCT
GGCGCTCATCCCTGGCTGCGTTGGTTCCTCGCCTATACAGAATATTGGCGCGTATGGCGTAGAACTACAGCGCGTCTGCG
ACTATGTTGACTGCGTTGAACTGGAAACGGGAAAACGTCTGCGTTTGTCTGCGGCGGAATGCCGTTTCGGCTATCGTGAC
AGCATCTTCAAAAATGAATATCAGGATCGCGTTGCGATCGTCGCGGTGGGTCTGCGTTTATCAAAGCAATGGCAGCCGGT
GTTGACCTATGGCGATCTTACTTGTCTGGACCCGAAAACGGTCACCGCGCAACAGGTGTTTGATGCTGTATGCCATATGC
GCACCACAAAATTGCCGGATCCTAAAGTGAATGGCAATGCGGGCAGCTTTTTTAAAAATCCCGTTGTCGCAGCCGATATC
GCTATGGAACTGTTAGAACGATTTCCCAACGCGCCGCATTACCCTCAGGCAGACGGCTCAGTGAAGCTGGCGGCAGGCTG
GCTGATAGACCAATGTCAGTTGAAAGGCGTCGCCATTGGCGGCGCTGCGGTACATCGCCAACAGGCGCTGGTATTGATTA
ATGCGAATGATGCGACAAGTAAAGATGTGGTGGCGCTGGCGCATCATGTCCGGCAAAAAGTGGGTGAAAAATTTAATGTC
TGGCTGGAGCCTGAGGTTCGCTTTATTGGTCGGTCCGGAGAGGTGAACGCTGTGGAGAGCATTGCATGA

Upstream 100 bases:

>100_bases
ACAATGCCTGTGTATACCGCCTTATTCCGTCGACATAACCGCAAGCCTTCCCTACATAGATGCGGTAAACTAAGCCTGAT
TTTGCATCAGGAAAGCAGCC

Downstream 100 bases:

>100_bases
AAGATACTACCGTTCCCCTGACGCTAATCTCACTACTTGCCGACGGAGAGTTTCACTCAGGCGAGCAGTTGGGTGAACGG
CTGGGAATGAGCCGCGCGGC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTHSLKPWNTFGIDHCAKHIVCAENEQQLLSAWQQATREGLPVMILGEGSNVLFLENYAGTVILNRLKGIEVNETADAWH
LHVGAGENWHQLVRYALDNNMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCDYVDCVELETGKRLRLSAAECRFGYRD
SIFKNEYQDRVAIVAVGLRLSKQWQPVLTYGDLTCLDPKTVTAQQVFDAVCHMRTTKLPDPKVNGNAGSFFKNPVVAADI
AMELLERFPNAPHYPQADGSVKLAAGWLIDQCQLKGVAIGGAAVHRQQALVLINANDATSKDVVALAHHVRQKVGEKFNV
WLEPEVRFIGRSGEVNAVESIA

Sequences:

>Translated_342_residues
MTHSLKPWNTFGIDHCAKHIVCAENEQQLLSAWQQATREGLPVMILGEGSNVLFLENYAGTVILNRLKGIEVNETADAWH
LHVGAGENWHQLVRYALDNNMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCDYVDCVELETGKRLRLSAAECRFGYRD
SIFKNEYQDRVAIVAVGLRLSKQWQPVLTYGDLTCLDPKTVTAQQVFDAVCHMRTTKLPDPKVNGNAGSFFKNPVVAADI
AMELLERFPNAPHYPQADGSVKLAAGWLIDQCQLKGVAIGGAAVHRQQALVLINANDATSKDVVALAHHVRQKVGEKFNV
WLEPEVRFIGRSGEVNAVESIA
>Mature_341_residues
THSLKPWNTFGIDHCAKHIVCAENEQQLLSAWQQATREGLPVMILGEGSNVLFLENYAGTVILNRLKGIEVNETADAWHL
HVGAGENWHQLVRYALDNNMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCDYVDCVELETGKRLRLSAAECRFGYRDS
IFKNEYQDRVAIVAVGLRLSKQWQPVLTYGDLTCLDPKTVTAQQVFDAVCHMRTTKLPDPKVNGNAGSFFKNPVVAADIA
MELLERFPNAPHYPQADGSVKLAAGWLIDQCQLKGVAIGGAAVHRQQALVLINANDATSKDVVALAHHVRQKVGEKFNVW
LEPEVRFIGRSGEVNAVESIA

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=342, Percent_Identity=82.1637426900585, Blast_Score=593, Evalue=1e-171,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 37617; Mature: 37486

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSLKPWNTFGIDHCAKHIVCAENEQQLLSAWQQATREGLPVMILGEGSNVLFLENYAG
CCCCCCCCCCCCHHHHHHHEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCC
TVILNRLKGIEVNETADAWHLHVGAGENWHQLVRYALDNNMPGLENLALIPGCVGSSPIQ
CHHHHHHCCCEECCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHH
NIGAYGVELQRVCDYVDCVELETGKRLRLSAAECRFGYRDSIFKNEYQDRVAIVAVGLRL
HHHHCCCHHHHHHCHHHHEECCCCCEEEEEHHHHCCCCHHHHHHHHHHCEEEEEEECCHH
SKQWQPVLTYGDLTCLDPKTVTAQQVFDAVCHMRTTKLPDPKVNGNAGSFFKNPVVAADI
CCCCCCEEEECCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHH
AMELLERFPNAPHYPQADGSVKLAAGWLIDQCQLKGVAIGGAAVHRQQALVLINANDATS
HHHHHHHCCCCCCCCCCCCCEEEEECEEEEEEEECEEEECCHHHHCCEEEEEEECCCCCC
KDVVALAHHVRQKVGEKFNVWLEPEVRFIGRSGEVNAVESIA
HHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCHHHHCC
>Mature Secondary Structure 
THSLKPWNTFGIDHCAKHIVCAENEQQLLSAWQQATREGLPVMILGEGSNVLFLENYAG
CCCCCCCCCCCHHHHHHHEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCC
TVILNRLKGIEVNETADAWHLHVGAGENWHQLVRYALDNNMPGLENLALIPGCVGSSPIQ
CHHHHHHCCCEECCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHH
NIGAYGVELQRVCDYVDCVELETGKRLRLSAAECRFGYRDSIFKNEYQDRVAIVAVGLRL
HHHHCCCHHHHHHCHHHHEECCCCCEEEEEHHHHCCCCHHHHHHHHHHCEEEEEEECCHH
SKQWQPVLTYGDLTCLDPKTVTAQQVFDAVCHMRTTKLPDPKVNGNAGSFFKNPVVAADI
CCCCCCEEEECCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHH
AMELLERFPNAPHYPQADGSVKLAAGWLIDQCQLKGVAIGGAAVHRQQALVLINANDATS
HHHHHHHCCCCCCCCCCCCCEEEEECEEEEEEEECEEEECCHHHHCCEEEEEEECCCCCC
KDVVALAHHVRQKVGEKFNVWLEPEVRFIGRSGEVNAVESIA
HHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA