Click here to switch to the map view.

The map label for this gene is crp [C]

Identifier: 194737343

GI number: 194737343

Start: 3996032

End: 3996823

Strand: Direct

Name: crp [C]

Synonym: SeSA_A4121

Alternate gene names: 194737343

Gene position: 3996032-3996823 (Clockwise)

Preceding gene: 194736177

Following gene: 194737261

Centisome position: 84.86

GC content: 50.0

Gene sequence:

>792_bases
ATGAACCGGGAGATAAGCGGCATTTTTAGCGGGCGTATTTCGGATGCGCGGGACGGCGGTCCTGTCCTTTCTGACAAGGG
GCGAGATACCATGAACATAATGAAAAACGCAGAATTTCCAGACGACTGGCTTTTAGGGCTACGCCAGGTTGTACGCGACC
CAGTGCTCTATGAATTACTCAAATACTGCCCGTTGGAAATCATGCAGTGTTGGCGATTTGACGACATTTCCCGCGGCGCG
CTTATCTGCCGCCAGGGGGAAATATGCCAGCAATTTTCACTCATCGTGGCCGGTGAAGTGGATGTTTTTTACGAAGCTGA
AGATGGACGCCGTTACCGGCAGGCGCGTTATGGCAAAGGAGACATGCTGGGTGAGCTAGAGATATTTGAGTCGCGGCATT
ACATCTGTTCTGTCGTAGCCGTCGGCAATGTACAGCTACTCAGCCTGCCGCAAGCGCATTTTTGCCGCTGGCTGACGCTG
GATAACCACTTTAACCAGCGAATGCTGCGGTTTTTCAGCCAACAGTATTACCAGTTGTCGAAAAAGGCCAGTAGCGACAA
TTTGTACTCGCTGCATCAACGCGTATGCCAGGCATTATGGCTGCGTTATCAACAATATGAATCAACCACTATTTTGCTTG
ATAAGCAGAATCTTGGTCAGGAATTTGCGGCGACGACGCGCAGTATCAACCGGATACTGCACGATCTGAAATCGCTGAAC
ATTATCGATACCGACGGTGAGCGGATCATTTTACTGGCTTCTGAAAAACTCAAACAGGAGGCGGAAATCTGA

Upstream 100 bases:

>100_bases
TGAGTTCTCACGTCGCAAAGATTGGCCGTCACTTTATCACTCCTTAGGCCGTCAGACATATACTCTTCGCCATTACAGGA
CAGATGTCCCGCCTGATTTA

Downstream 100 bases:

>100_bases
ACCTCTCAGAACAATAAGGAGACGGGAGATGCAACCCCATATTCGGCTTAACACAAGCATGACCCGCGCGAAATATGCGC
TTTTGCCCGGCGATCCCGGA

Product: cyclic nucleotide-binding domain-containing protein

Products: NA

Alternate protein names: Transcriptional Regulatory Protein; Transcriptional Regulator Crp/Fnr Family Protein

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MNREISGIFSGRISDARDGGPVLSDKGRDTMNIMKNAEFPDDWLLGLRQVVRDPVLYELLKYCPLEIMQCWRFDDISRGA
LICRQGEICQQFSLIVAGEVDVFYEAEDGRRYRQARYGKGDMLGELEIFESRHYICSVVAVGNVQLLSLPQAHFCRWLTL
DNHFNQRMLRFFSQQYYQLSKKASSDNLYSLHQRVCQALWLRYQQYESTTILLDKQNLGQEFAATTRSINRILHDLKSLN
IIDTDGERIILLASEKLKQEAEI

Sequences:

>Translated_263_residues
MNREISGIFSGRISDARDGGPVLSDKGRDTMNIMKNAEFPDDWLLGLRQVVRDPVLYELLKYCPLEIMQCWRFDDISRGA
LICRQGEICQQFSLIVAGEVDVFYEAEDGRRYRQARYGKGDMLGELEIFESRHYICSVVAVGNVQLLSLPQAHFCRWLTL
DNHFNQRMLRFFSQQYYQLSKKASSDNLYSLHQRVCQALWLRYQQYESTTILLDKQNLGQEFAATTRSINRILHDLKSLN
IIDTDGERIILLASEKLKQEAEI
>Mature_263_residues
MNREISGIFSGRISDARDGGPVLSDKGRDTMNIMKNAEFPDDWLLGLRQVVRDPVLYELLKYCPLEIMQCWRFDDISRGA
LICRQGEICQQFSLIVAGEVDVFYEAEDGRRYRQARYGKGDMLGELEIFESRHYICSVVAVGNVQLLSLPQAHFCRWLTL
DNHFNQRMLRFFSQQYYQLSKKASSDNLYSLHQRVCQALWLRYQQYESTTILLDKQNLGQEFAATTRSINRILHDLKSLN
IIDTDGERIILLASEKLKQEAEI

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30561; Mature: 30561

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNREISGIFSGRISDARDGGPVLSDKGRDTMNIMKNAEFPDDWLLGLRQVVRDPVLYELL
CCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHH
KYCPLEIMQCWRFDDISRGALICRQGEICQQFSLIVAGEVDVFYEAEDGRRYRQARYGKG
HHCCHHHHHHHCCCCCCCCEEEECCCHHHHHHHEEEECCEEEEEECCCCHHHHHHHCCCC
DMLGELEIFESRHYICSVVAVGNVQLLSLPQAHFCRWLTLDNHFNQRMLRFFSQQYYQLS
CCCCHHHHHHCCCCEEEEEEECCEEEEECCHHHHEEEEEECCHHHHHHHHHHHHHHHHHH
KKASSDNLYSLHQRVCQALWLRYQQYESTTILLDKQNLGQEFAATTRSINRILHDLKSLN
HHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHCCHHHHHHHHHHHHHHHHHHHCC
IIDTDGERIILLASEKLKQEAEI
EEECCCCEEEEEECHHHHHHCCC
>Mature Secondary Structure
MNREISGIFSGRISDARDGGPVLSDKGRDTMNIMKNAEFPDDWLLGLRQVVRDPVLYELL
CCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHH
KYCPLEIMQCWRFDDISRGALICRQGEICQQFSLIVAGEVDVFYEAEDGRRYRQARYGKG
HHCCHHHHHHHCCCCCCCCEEEECCCHHHHHHHEEEECCEEEEEECCCCHHHHHHHCCCC
DMLGELEIFESRHYICSVVAVGNVQLLSLPQAHFCRWLTLDNHFNQRMLRFFSQQYYQLS
CCCCHHHHHHCCCCEEEEEEECCEEEEECCHHHHEEEEEECCHHHHHHHHHHHHHHHHHH
KKASSDNLYSLHQRVCQALWLRYQQYESTTILLDKQNLGQEFAATTRSINRILHDLKSLN
HHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHCCHHHHHHHHHHHHHHHHHHHCC
IIDTDGERIILLASEKLKQEAEI
EEECCCCEEEEEECHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA