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The map label for this gene is dipZ [H]

Identifier: 194737290

GI number: 194737290

Start: 4467270

End: 4468973

Strand: Reverse

Name: dipZ [H]

Synonym: SeSA_A4593

Alternate gene names: 194737290

Gene position: 4468973-4467270 (Counterclockwise)

Preceding gene: 194734784

Following gene: 194738081

Centisome position: 94.9

GC content: 56.69

Gene sequence:

>1704_bases
ATGGCTCAACGCATCTTTACGCTGATCCTGCTGCTGTGCAGCACATCCGCCTTCGCCGGATTATTCGACGCGCCGGGTCG
CTCGCAGTTCGTCCCTGCCGACCGGGCGTTTGTTTTTGATTTTCAGCAAAATCAACACGATCTTACCCTCTCCTGGCAGG
TAAAAGAGGGTTACTACCTTTACCGTAAACAAATCAGCATCACGCCAACGAAAGCGGATATCGCCGCAGTCCAACTCCCG
GCAGGCGTCTGGCATGAAGATGAATTCTACGGAAAAAGCGAAATCTACCGTAAGCGGCTAAACGTTCCGGTAACGGTTAA
CCAGGCGGCGGCTGGCGCGACATTAACGGTAACGTACCAGGGGTGCGCCGATGCGGGATTCTGTTATCCGCCGGAAACGA
AAACGGTGCCGCTAAGTGAAGTCGCCGCGGCAATAGACGCCACGCCGACGCCTGCTGTCACCCAGACGAGTGAGACGTCA
AAACCCGCCGCCCAGCTACCTTTTTCCGCGCTCTGGGCACTGCTGATCGGCATAGGCATCGCCTTTACGCCCTGCGTTTT
ACCCATGTATCCGCTGATTTCCGGTATTGTCCTGGGGGGAAGGCAACGTTTGTCGACGGGGCGCGCACTGCTGCTGGCCT
TTATCTATGTACAAGGGATGGCGCTGACCTATACCGCACTGGGTCTGGTCGTCGCCGCAGCGGGATTACAGTTTCAGGCG
GCGCTGCAGCACCCTTATGTGTTAATCGGCCTTGCCATCGTGTTCACCCTGCTTGCGTTGTCGATGTTTGGCCTGTTCAC
ACTACAGCTCCCCTCCTCACTGCAAACCCGGCTGACATTAATGAGTAATCGTCAGCAAGGCGGCTCGCCCGGCGGTGTTT
TTGTTATGGGGGCGATTGCCGGATTAATTTGCTCGCCCTGCACTACAGCGCCGTTAAGCGCGATTCTGCTTTATATCGCT
CAGAGCGGCAACATGTGGCTGGGCGGCGGCACGCTGTATTTGTATGCATTAGGTATGGGTCTGCCGCTAATGCTGGTCAC
CGTGTTTGGCAACCGTCTGCTACCGAAAAGCGGCCCGTGGATGGCGCATGTTAAAACCGCTTTTGGTTTCGTGATCCTCG
CGTTACCGGTCTTTTTACTGGAGCGGATTATTGGCGAGGCTTGGGGTTTACGTCTGTGGTCGCTGCTGGGCGTCGCTTTC
TTTGGTTGGGCCTTTATCACCAGCCTTCAGGCCAGACGAGCGTGGATGCGTATCGTACAGATTATCCTGCTGGCGGCTGC
GCTCATTAGCGTGCGGCCTCTACAGGATTGGGCGTTCGGATCGCCATCCGCGCAAGCTCCAGCGCACCTCAATTTCACGG
CTATTTCTACCGTGGACGAACTCAATCAGGCGCTGGCGCAGGCCAAAGGCAAACCCGTTATGCTGGATTTCTACGCCGAC
TGGTGCGTGGCCTGTAAAGAGTTTGAAAAGTATACCTTCAGCGATCCGCGGGTCCAGCAGGCGCTCGGCGACACGGTGCT
CTTGCAGGCTAACGTCACCGCTAACAATGCGCAGGATGTCGCGCTGTTAAAGCATCTGCAAGTCCTCGGGCTGCCCACCA
TTCTGTTCTTTAATGCCCAAGGCCAGGAACAGCCGCAATCGCGAGTCACCGGCTTTATGGACGCCGCCACCTTTAGCGCG
CATTTGCACGATCGCCAACCGTGA

Upstream 100 bases:

>100_bases
ATCAGCAAGCGCTTATCGACTGCCTGAAGTCTCATCACCCGTATCAAACGCCTGAACTTCTGGTTTTACCTGTTACTCAC
GGAGATACTGATTACCTCTC

Downstream 100 bases:

>100_bases
GCGACACTTGCAAAAGCAAAGACGGAGGAGAATACCGTGCAACGTGAAGATATTCTGGGAGAAGCCCTGAAATTACTGGA
GACGCAAGGGATAGCCGATA

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MAQRIFTLILLLCSTSAFAGLFDAPGRSQFVPADRAFVFDFQQNQHDLTLSWQVKEGYYLYRKQISITPTKADIAAVQLP
AGVWHEDEFYGKSEIYRKRLNVPVTVNQAAAGATLTVTYQGCADAGFCYPPETKTVPLSEVAAAIDATPTPAVTQTSETS
KPAAQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGRQRLSTGRALLLAFIYVQGMALTYTALGLVVAAAGLQFQA
ALQHPYVLIGLAIVFTLLALSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIA
QSGNMWLGGGTLYLYALGMGLPLMLVTVFGNRLLPKSGPWMAHVKTAFGFVILALPVFLLERIIGEAWGLRLWSLLGVAF
FGWAFITSLQARRAWMRIVQIILLAAALISVRPLQDWAFGSPSAQAPAHLNFTAISTVDELNQALAQAKGKPVMLDFYAD
WCVACKEFEKYTFSDPRVQQALGDTVLLQANVTANNAQDVALLKHLQVLGLPTILFFNAQGQEQPQSRVTGFMDAATFSA
HLHDRQP

Sequences:

>Translated_567_residues
MAQRIFTLILLLCSTSAFAGLFDAPGRSQFVPADRAFVFDFQQNQHDLTLSWQVKEGYYLYRKQISITPTKADIAAVQLP
AGVWHEDEFYGKSEIYRKRLNVPVTVNQAAAGATLTVTYQGCADAGFCYPPETKTVPLSEVAAAIDATPTPAVTQTSETS
KPAAQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGRQRLSTGRALLLAFIYVQGMALTYTALGLVVAAAGLQFQA
ALQHPYVLIGLAIVFTLLALSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIA
QSGNMWLGGGTLYLYALGMGLPLMLVTVFGNRLLPKSGPWMAHVKTAFGFVILALPVFLLERIIGEAWGLRLWSLLGVAF
FGWAFITSLQARRAWMRIVQIILLAAALISVRPLQDWAFGSPSAQAPAHLNFTAISTVDELNQALAQAKGKPVMLDFYAD
WCVACKEFEKYTFSDPRVQQALGDTVLLQANVTANNAQDVALLKHLQVLGLPTILFFNAQGQEQPQSRVTGFMDAATFSA
HLHDRQP
>Mature_566_residues
AQRIFTLILLLCSTSAFAGLFDAPGRSQFVPADRAFVFDFQQNQHDLTLSWQVKEGYYLYRKQISITPTKADIAAVQLPA
GVWHEDEFYGKSEIYRKRLNVPVTVNQAAAGATLTVTYQGCADAGFCYPPETKTVPLSEVAAAIDATPTPAVTQTSETSK
PAAQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGRQRLSTGRALLLAFIYVQGMALTYTALGLVVAAAGLQFQAA
LQHPYVLIGLAIVFTLLALSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQ
SGNMWLGGGTLYLYALGMGLPLMLVTVFGNRLLPKSGPWMAHVKTAFGFVILALPVFLLERIIGEAWGLRLWSLLGVAFF
GWAFITSLQARRAWMRIVQIILLAAALISVRPLQDWAFGSPSAQAPAHLNFTAISTVDELNQALAQAKGKPVMLDFYADW
CVACKEFEKYTFSDPRVQQALGDTVLLQANVTANNAQDVALLKHLQVLGLPTILFFNAQGQEQPQSRVTGFMDAATFSAH
LHDRQP

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=568, Percent_Identity=87.5, Blast_Score=1011, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 61359; Mature: 61228

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRIFTLILLLCSTSAFAGLFDAPGRSQFVPADRAFVFDFQQNQHDLTLSWQVKEGYYL
CHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCEEE
YRKQISITPTKADIAAVQLPAGVWHEDEFYGKSEIYRKRLNVPVTVNQAAAGATLTVTYQ
EEEEEEECCCCCCCEEEEECCCCCCCHHHCCHHHHHHHHCCCCEEECCCCCCCEEEEEEC
GCADAGFCYPPETKTVPLSEVAAAIDATPTPAVTQTSETSKPAAQLPFSALWALLIGIGI
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHH
AFTPCVLPMYPLISGIVLGGRQRLSTGRALLLAFIYVQGMALTYTALGLVVAAAGLQFQA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ALQHPYVLIGLAIVFTLLALSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIA
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
GLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYALGMGLPLMLVTVFGNRLLPKSGPW
HHHCCCCCCHHHHHHHHHHHCCCCEEECCCHHEEHHHHCCHHHHHHHHHCCCCCCCCCCC
MAHVKTAFGFVILALPVFLLERIIGEAWGLRLWSLLGVAFFGWAFITSLQARRAWMRIVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IILLAAALISVRPLQDWAFGSPSAQAPAHLNFTAISTVDELNQALAQAKGKPVMLDFYAD
HHHHHHHHHHCCCCHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEEHHH
WCVACKEFEKYTFSDPRVQQALGDTVLLQANVTANNAQDVALLKHLQVLGLPTILFFNAQ
HHHHHHHHHHCCCCCCHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECC
GQEQPQSRVTGFMDAATFSAHLHDRQP
CCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AQRIFTLILLLCSTSAFAGLFDAPGRSQFVPADRAFVFDFQQNQHDLTLSWQVKEGYYL
HHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCEEE
YRKQISITPTKADIAAVQLPAGVWHEDEFYGKSEIYRKRLNVPVTVNQAAAGATLTVTYQ
EEEEEEECCCCCCCEEEEECCCCCCCHHHCCHHHHHHHHCCCCEEECCCCCCCEEEEEEC
GCADAGFCYPPETKTVPLSEVAAAIDATPTPAVTQTSETSKPAAQLPFSALWALLIGIGI
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHH
AFTPCVLPMYPLISGIVLGGRQRLSTGRALLLAFIYVQGMALTYTALGLVVAAAGLQFQA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ALQHPYVLIGLAIVFTLLALSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIA
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
GLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYALGMGLPLMLVTVFGNRLLPKSGPW
HHHCCCCCCHHHHHHHHHHHCCCCEEECCCHHEEHHHHCCHHHHHHHHHCCCCCCCCCCC
MAHVKTAFGFVILALPVFLLERIIGEAWGLRLWSLLGVAFFGWAFITSLQARRAWMRIVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IILLAAALISVRPLQDWAFGSPSAQAPAHLNFTAISTVDELNQALAQAKGKPVMLDFYAD
HHHHHHHHHHCCCCHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEEHHH
WCVACKEFEKYTFSDPRVQQALGDTVLLQANVTANNAQDVALLKHLQVLGLPTILFFNAQ
HHHHHHHHHHCCCCCCHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECC
GQEQPQSRVTGFMDAATFSAHLHDRQP
CCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA