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The map label for this gene is udp [H]

Identifier: 194737261

GI number: 194737261

Start: 3996852

End: 3997595

Strand: Direct

Name: udp [H]

Synonym: SeSA_A4122

Alternate gene names: 194737261

Gene position: 3996852-3997595 (Clockwise)

Preceding gene: 194737343

Following gene: 194734953

Centisome position: 84.88

GC content: 57.66

Gene sequence:

>744_bases
ATGCAACCCCATATTCGGCTTAACACAAGCATGACCCGCGCGAAATATGCGCTTTTGCCCGGCGATCCCGGACGGGTGGA
TAGAATCGCCCGTTTTCTTGATAAGGCTGAGATTCTGGGGCAAAACCGGGAGTTTCGCGCGGCGCGCGGTTGGTACCAGG
GTGTTGAAATAGTCGTGCTTTCCACGGGAATCGGCGGACCGTCAACCGCTATCGCCATTGAGGAGTTACGCCAGGTTGGC
GTCAACTCGCTAATCCGTATCGGTAGTTGCGGCGCGTTGCAGGACTCGCTGGCGTTGGGCGATGTGATCATCGCCCACGG
CGCGGTGGCTGACGACGGCGCCAGCAAAACCTATGCGCCCGCCAGTTATCCGGCCTGTGCGGACCCGTATCTTACCGCCA
CGCTGATACAGCAGGCGAAACAGATGAACATCTCTGCCGTTTGCGGGCTGGTGCGCAGCCATGACAGTTTTTATACCGAT
CGCGAAGCTGAACTGGATGCCGAATGGTCGGCCAGGGGAGTTCTCGGCGCGGATATGGAAACCGCCGCGCTGATGGTGGT
GGGGGCGTTACGTGGGCTGCGTACCGCGTCGTTGCTAAACGTGGTCGTCGCGCATAGTGGCTGTCTGGAGAGCAGCATTA
ACCATTATGTTCAGCAGGAAACCTTGTGCCAGCAAGGTGAAGAGCGCCAGATTTCTTTGGCGCTTCAGGCCATTTATTTC
GATAGTTTGCAAGGAGAGCAATGA

Upstream 100 bases:

>100_bases
ATTATCGATACCGACGGTGAGCGGATCATTTTACTGGCTTCTGAAAAACTCAAACAGGAGGCGGAAATCTGAACCTCTCA
GAACAATAAGGAGACGGGAG

Downstream 100 bases:

>100_bases
TGGACTTTTTCATCATTAACAATGTAATGGTCAACATTCCTCTCGGCGAGGGAGGGTATGCGCTGTCGTGGATTGAGGCT
ATCGGCACCGTCTTTGGCTT

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MQPHIRLNTSMTRAKYALLPGDPGRVDRIARFLDKAEILGQNREFRAARGWYQGVEIVVLSTGIGGPSTAIAIEELRQVG
VNSLIRIGSCGALQDSLALGDVIIAHGAVADDGASKTYAPASYPACADPYLTATLIQQAKQMNISAVCGLVRSHDSFYTD
REAELDAEWSARGVLGADMETAALMVVGALRGLRTASLLNVVVAHSGCLESSINHYVQQETLCQQGEERQISLALQAIYF
DSLQGEQ

Sequences:

>Translated_247_residues
MQPHIRLNTSMTRAKYALLPGDPGRVDRIARFLDKAEILGQNREFRAARGWYQGVEIVVLSTGIGGPSTAIAIEELRQVG
VNSLIRIGSCGALQDSLALGDVIIAHGAVADDGASKTYAPASYPACADPYLTATLIQQAKQMNISAVCGLVRSHDSFYTD
REAELDAEWSARGVLGADMETAALMVVGALRGLRTASLLNVVVAHSGCLESSINHYVQQETLCQQGEERQISLALQAIYF
DSLQGEQ
>Mature_247_residues
MQPHIRLNTSMTRAKYALLPGDPGRVDRIARFLDKAEILGQNREFRAARGWYQGVEIVVLSTGIGGPSTAIAIEELRQVG
VNSLIRIGSCGALQDSLALGDVIIAHGAVADDGASKTYAPASYPACADPYLTATLIQQAKQMNISAVCGLVRSHDSFYTD
REAELDAEWSARGVLGADMETAALMVVGALRGLRTASLLNVVVAHSGCLESSINHYVQQETLCQQGEERQISLALQAIYF
DSLQGEQ

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=204, Percent_Identity=39.7058823529412, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1790844, Length=203, Percent_Identity=33.9901477832512, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 26519; Mature: 26519

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPHIRLNTSMTRAKYALLPGDPGRVDRIARFLDKAEILGQNREFRAARGWYQGVEIVVL
CCCCEEECCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEE
STGIGGPSTAIAIEELRQVGVNSLIRIGSCGALQDSLALGDVIIAHGAVADDGASKTYAP
ECCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
ASYPACADPYLTATLIQQAKQMNISAVCGLVRSHDSFYTDREAELDAEWSARGVLGADME
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
TAALMVVGALRGLRTASLLNVVVAHSGCLESSINHYVQQETLCQQGEERQISLALQAIYF
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
DSLQGEQ
HHCCCCC
>Mature Secondary Structure
MQPHIRLNTSMTRAKYALLPGDPGRVDRIARFLDKAEILGQNREFRAARGWYQGVEIVVL
CCCCEEECCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEE
STGIGGPSTAIAIEELRQVGVNSLIRIGSCGALQDSLALGDVIIAHGAVADDGASKTYAP
ECCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
ASYPACADPYLTATLIQQAKQMNISAVCGLVRSHDSFYTDREAELDAEWSARGVLGADME
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
TAALMVVGALRGLRTASLLNVVVAHSGCLESSINHYVQQETLCQQGEERQISLALQAIYF
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
DSLQGEQ
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]