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The map label for this gene is putA [H]

Identifier: 194737127

GI number: 194737127

Start: 1166271

End: 1170233

Strand: Reverse

Name: putA [H]

Synonym: SeSA_A1188

Alternate gene names: 194737127

Gene position: 1170233-1166271 (Counterclockwise)

Preceding gene: 194737668

Following gene: 194736498

Centisome position: 24.85

GC content: 59.15

Gene sequence:

>3963_bases
ATGGGAACCACCACGATGGGGGTTAAGCTGGACGACGCCACGCGCGAACGGATCAAAATGGCCGCCTCGCGTATCGATCG
CACGCCGCACTGGTTAATAAAACAGGCAATCTTTAGCTATCTGGACAAGCTGGAAAATAGCGATACGCTACCGGAGCTAC
CTGCGCTGTTTGCCGGCGCGGCAAATGAAAGCGAGGAGCCGGTCGCGCCGCAGGATGAGCCGCATCAGCCCTTTCTGGAG
TTTGCCGAACAGATTCTTCCCCAATCCGTCTCTCGCGCCGCCATCACTGCCGCCTGGCGCCGCCCGGAAACCGATGCGGT
GTCAATGCTAGTGGAACAGGCGCGCCTGTCGCCGCCTGTCGCTGAGCAGGCGCATAAACTGGCGTATCAACTGGCGGAGA
AATTGCGCAATCAAAAATCCGCCAGCGGTCGCGCGGGTATGGTACAAGGCCTGTTGCAGGAGTTTTCCCTCTCTTCGCAA
GAAGGTGTTGCGCTGATGTGTCTGGCGGAAGCGCTGCTGCGTATTCCCGACAAAGCTACGCGCGATGCGTTAATTCGCGA
CAAAATCAGTAATGGCAACTGGCAGTCGCATATTGGCCGTAGCCCGTCGCTGTTTGTAAACGCCGCCACCTGGGGGCTGC
TCTTTACCGGCCGACTGGTCTCAACGCATAACGAAGCTAATCTTTCACGCTCGCTGAACCGCATTATCGGCAAGAGCGGC
GAACCGTTAATCCGCAAAGGCGTCGACATGGCGATGCGTTTAATGGGCGAGCAGTTCGTGACTGGCGAAACCATTGCTCA
GGCGCTGGCGAATGCCCGAAAACTGGAAGAGAAAGGGTTCCGCTATTCTTACGATATGCTGGGCGAAGCCGCGTTAACCG
CCGCCGATGCGCAGGCGTATATGGTTTCTTACCAGCAAGCGATTCATGCCATCGGCAAAGCGTCTAACGGTCGCGGTATT
TACGAAGGGCCAGGCATCTCGATTAAGCTGTCCGCCCTGCATCCACGCTATAGTCGCGCGCAATACGATCGGGTAATGGA
GGAGCTTTATCCGCGCCTGAAATCCCTGACGCTGCTGGCGCGCCAGTATGATATCGGTCTCAATATCGACGCCGAAGAGG
CGGATCGTCTGGAGATCTCGCTCGATCTGCTGGAAAAACTCTGCTTCGAACCCGAACTGGCGGGCTGGAACGGCATTGGC
TTTGTGATCCAGGCTTACCAGAAACGCTGCCCGCTGGTCATTGATTATTTAGTCGATCTGGCCTCCCGTAGCCGCCGTCG
GCTGATGATTCGTCTGGTGAAAGGCGCCTACTGGGATAGCGAGATCAAACGCGCGCAAATGGAAGGGCTGGAGGGCTATC
CGGTTTATACCCGCAAAGTGTATACCGATGTCTCTTATCTGGCCTGCGCGAAAAAACTGCTCGCGGTCCCTAATCTGATC
TACCCGCAGTTCGCGACCCATAACGCACACACACTGGCGGCGATTTATCATCTGGCCGGGCAAAATTACTATCCGGGTCA
GTACGAATTCCAGTGCCTGCACGGCATGGGCGAACCGCTGTATGAACAGGTCACCGGTAAAGTGGCGGACGGAAAACTTA
ACCGTCCCTGCCGTATTTACGCGCCGGTGGGAACGCACGAAACCCTGCTGGCCTATCTGGTACGACGCCTGCTGGAAAAC
GGCGCCAACACCTCTTTTGTCAACCGCATCGCCGATGCCACCCTACCGCTCGATGAACTGGTGGCCGACCCGGTCGAGGC
CGTGGAAAAACTGGCGCAGCAGGAAGGTCAGGCTGGCATACCGCATCCGAAAATTCCGCTGCCGCGCGATCTGTACGGCG
AAGGTCGGATAAACTCCGCCGGACTTGATTTAGCGAATGAACATCGCCTCGCCTCGCTTTCTTCTGCCCTGTTAAGCAAC
GCCATGCAGAAATGGCAGGCCAAACCTGTGCTGGAACAACCGGTGGCCGACGGTGAGATGACGCCGGTTATCAACCCGGC
GGAACCGAAAGATATTGTCGGCTGGGGACGCGAAGCGACAGAAAGCGAGGTTGAACAGGCATTGCAAAACGCGGTCAATC
AGGCGCCGGTTTGGTTTGCGACGCCGCCGCAAGAACGCGCCGCCATTTTGCAGCGGGCGGCGGTATTGATGGAAGACCAA
ATGCAGCAGTTGATTGGCCTGTTGGTGCGCGAAGCGGGGAAAACGTTCAGCAACGCCATTGCCGAAGTGCGCGAAGCGGT
AGACTTCCTCCATTATTATGCCGGTCAAGTGCGTGACGATTTCGATAACGAAACGCATCGCCCGTTAGGGCCGGTGGTCT
GTATCAGTCCGTGGAACTTCCCGCTGGCCATTTTCACCGGCCAAATCGCCGCCGCGCTGGCGGCAGGTAACAGCGTTCTG
GCGAAACCGGCAGAGCAGACATCGCTGATTGCCGCCCAGGGCATTGCCATTTTGCTGGAAGCGGGCGTACCGCCGGGCGT
CGTGCAACTGTTGCCGGGACGGGGAGAAACCGTCGGCGCCCAGCTTACCGCCGATGCGCGTGTACGCGGCGTGATGTTTA
CCGGTTCCACGGAGGTCGCGACGTTGTTGCAGCGCAACATCGCCACGCGTCTTGACGCCCAGGGCCGCCCTATTCCGTTG
ATTGCGGAAACTGGCGGTATGAACGCTATGATTGTCGACTCTTCCGCGCTCACCGAGCAGGTGGTCGTGGATGTGCTGGC
TTCCGCTTTCGACAGCGCCGGACAACGCTGTTCCGCGCTCCGCGTGCTGTGTTTGCAGGACGATATCGCCGAACATACGC
TGAAAATGTTACGCGGCGCGATGGCGGAGTGTCGGATGGGGAATCCAGGCCGTCTGACGACCGATATCGGGCCGGTGATT
GATAGCGAGGCCAAAGCCAACATCGAGCGTCATATCCAGACGATGCGCGCCAAAGGCCGCCCGGTTTTCCAGGCCGCGCG
TGAAAACAACGATGACGCGCAGGAATGGCAGACCGGTACGTTTGTTATGCCCACGCTTATTGAGTTGGAAAACTTCGCAG
AACTGGAAAAAGAGGTCTTCGGGCCCGTGCTGCATGTCGTGCGTTATAACCGTAACCAACTGGCGGAGCTTATCGAACAG
ATTAACGCTTCCGGCTACGGGCTAACGCTGGGCGTACATACCCGTATTGATGAAACCATTGCGCAAGTCACCGGTTCCGC
CCATGTCGGCAACCTGTACGTTAACCGTAATATGGTGGGCGCGGTTGTCGGCGTCCAGCCGTTTGGCGGCGAAGGCCTGT
CCGGTACCGGGCCAAAAGCGGGGGGGCCGCTCTACCTCTACCGCCTGCTGGCACACCGCCCGCCCAATGCGCTCAATACG
ACGCTAACTCGTCAGGATGCGCGTTACCCGGTGGATGCGCAGCTTAAAACCACGCTACTCGCGCCGTTGACCGCCCTGAC
GCAATGGGCGGCGGATCGCCCGGCGCTACAGACGCTCTGCCGACAATTCGCCGATCTGGCGCAGGCCGGCACGCAGCGCC
TGCTACCGGGGCCGACCGGCGAGCGCAATACCTGGACGTTGTTGCCGCGTGAACGGGTATTATGCCTGGCTGATGACGAA
CAGGACGCGCTGACGCAGCTTGCCGCCGTTCTCGCCGTCGGCAGTCAGGCGCTATGGTCAGACGACGCCTTCCACCGCGA
TCTGGCGAAACGTCTCCCCGCCGCCGTTGCGGCGCGTGTCCAGTTTGCGAAAGCGGAAACGCTGATGGCGCAGCCGTTTG
ACGCGGTGATTTTCCACGGCGACTCCGACAAGCTGCGAACCGTGTGCGAAGCCGTCGCCGCCCGCGAAGGCGCGATAGTG
TCGGTACAGGGGTTCGCCCGCGGCGAAAGCAATATGCTGCTGGAACGGCTCTATATTGAACGTTCGCTGAGCGTAAACAC
TGCTGCCGCTGGCGGTAATGCCAGCCTGATGACAATTGGCTAA

Upstream 100 bases:

>100_bases
CGCAGGTCACATTTAACGCGGTTGCACAAAGTTGCAACATAGTGGATATTTTCCGCTAACTATTGGTTAGCAGATAGAGC
GAATAACAGGAGTAGAGGGT

Downstream 100 bases:

>100_bases
TACTGTGGTTAATTAAGGCTCCGTCAATGGAGCCTTTTTACTCGCGTCAGAGGAGCGTATGAAACGAATTTTCCTTACCT
GCGCGGCGTTGTTGTTCAGC

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1320; Mature: 1319

Protein sequence:

>1320_residues
MGTTTMGVKLDDATRERIKMAASRIDRTPHWLIKQAIFSYLDKLENSDTLPELPALFAGAANESEEPVAPQDEPHQPFLE
FAEQILPQSVSRAAITAAWRRPETDAVSMLVEQARLSPPVAEQAHKLAYQLAEKLRNQKSASGRAGMVQGLLQEFSLSSQ
EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGRLVSTHNEANLSRSLNRIIGKSG
EPLIRKGVDMAMRLMGEQFVTGETIAQALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGI
YEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGLNIDAEEADRLEISLDLLEKLCFEPELAGWNGIG
FVIQAYQKRCPLVIDYLVDLASRSRRRLMIRLVKGAYWDSEIKRAQMEGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLI
YPQFATHNAHTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLEN
GANTSFVNRIADATLPLDELVADPVEAVEKLAQQEGQAGIPHPKIPLPRDLYGEGRINSAGLDLANEHRLASLSSALLSN
AMQKWQAKPVLEQPVADGEMTPVINPAEPKDIVGWGREATESEVEQALQNAVNQAPVWFATPPQERAAILQRAAVLMEDQ
MQQLIGLLVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFDNETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVL
AKPAEQTSLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTADARVRGVMFTGSTEVATLLQRNIATRLDAQGRPIPL
IAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDDIAEHTLKMLRGAMAECRMGNPGRLTTDIGPVI
DSEAKANIERHIQTMRAKGRPVFQAARENNDDAQEWQTGTFVMPTLIELENFAELEKEVFGPVLHVVRYNRNQLAELIEQ
INASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLAHRPPNALNT
TLTRQDARYPVDAQLKTTLLAPLTALTQWAADRPALQTLCRQFADLAQAGTQRLLPGPTGERNTWTLLPRERVLCLADDE
QDALTQLAAVLAVGSQALWSDDAFHRDLAKRLPAAVAARVQFAKAETLMAQPFDAVIFHGDSDKLRTVCEAVAAREGAIV
SVQGFARGESNMLLERLYIERSLSVNTAAAGGNASLMTIG

Sequences:

>Translated_1320_residues
MGTTTMGVKLDDATRERIKMAASRIDRTPHWLIKQAIFSYLDKLENSDTLPELPALFAGAANESEEPVAPQDEPHQPFLE
FAEQILPQSVSRAAITAAWRRPETDAVSMLVEQARLSPPVAEQAHKLAYQLAEKLRNQKSASGRAGMVQGLLQEFSLSSQ
EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGRLVSTHNEANLSRSLNRIIGKSG
EPLIRKGVDMAMRLMGEQFVTGETIAQALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGI
YEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGLNIDAEEADRLEISLDLLEKLCFEPELAGWNGIG
FVIQAYQKRCPLVIDYLVDLASRSRRRLMIRLVKGAYWDSEIKRAQMEGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLI
YPQFATHNAHTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLEN
GANTSFVNRIADATLPLDELVADPVEAVEKLAQQEGQAGIPHPKIPLPRDLYGEGRINSAGLDLANEHRLASLSSALLSN
AMQKWQAKPVLEQPVADGEMTPVINPAEPKDIVGWGREATESEVEQALQNAVNQAPVWFATPPQERAAILQRAAVLMEDQ
MQQLIGLLVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFDNETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVL
AKPAEQTSLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTADARVRGVMFTGSTEVATLLQRNIATRLDAQGRPIPL
IAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDDIAEHTLKMLRGAMAECRMGNPGRLTTDIGPVI
DSEAKANIERHIQTMRAKGRPVFQAARENNDDAQEWQTGTFVMPTLIELENFAELEKEVFGPVLHVVRYNRNQLAELIEQ
INASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLAHRPPNALNT
TLTRQDARYPVDAQLKTTLLAPLTALTQWAADRPALQTLCRQFADLAQAGTQRLLPGPTGERNTWTLLPRERVLCLADDE
QDALTQLAAVLAVGSQALWSDDAFHRDLAKRLPAAVAARVQFAKAETLMAQPFDAVIFHGDSDKLRTVCEAVAAREGAIV
SVQGFARGESNMLLERLYIERSLSVNTAAAGGNASLMTIG
>Mature_1319_residues
GTTTMGVKLDDATRERIKMAASRIDRTPHWLIKQAIFSYLDKLENSDTLPELPALFAGAANESEEPVAPQDEPHQPFLEF
AEQILPQSVSRAAITAAWRRPETDAVSMLVEQARLSPPVAEQAHKLAYQLAEKLRNQKSASGRAGMVQGLLQEFSLSSQE
GVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGRLVSTHNEANLSRSLNRIIGKSGE
PLIRKGVDMAMRLMGEQFVTGETIAQALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIY
EGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGLNIDAEEADRLEISLDLLEKLCFEPELAGWNGIGF
VIQAYQKRCPLVIDYLVDLASRSRRRLMIRLVKGAYWDSEIKRAQMEGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIY
PQFATHNAHTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENG
ANTSFVNRIADATLPLDELVADPVEAVEKLAQQEGQAGIPHPKIPLPRDLYGEGRINSAGLDLANEHRLASLSSALLSNA
MQKWQAKPVLEQPVADGEMTPVINPAEPKDIVGWGREATESEVEQALQNAVNQAPVWFATPPQERAAILQRAAVLMEDQM
QQLIGLLVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFDNETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLA
KPAEQTSLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTADARVRGVMFTGSTEVATLLQRNIATRLDAQGRPIPLI
AETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDDIAEHTLKMLRGAMAECRMGNPGRLTTDIGPVID
SEAKANIERHIQTMRAKGRPVFQAARENNDDAQEWQTGTFVMPTLIELENFAELEKEVFGPVLHVVRYNRNQLAELIEQI
NASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLAHRPPNALNTT
LTRQDARYPVDAQLKTTLLAPLTALTQWAADRPALQTLCRQFADLAQAGTQRLLPGPTGERNTWTLLPRERVLCLADDEQ
DALTQLAAVLAVGSQALWSDDAFHRDLAKRLPAAVAARVQFAKAETLMAQPFDAVIFHGDSDKLRTVCEAVAAREGAIVS
VQGFARGESNMLLERLYIERSLSVNTAAAGGNASLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=522, Percent_Identity=29.3103448275862, Blast_Score=178, Evalue=3e-44,
Organism=Homo sapiens, GI25777734, Length=522, Percent_Identity=29.3103448275862, Blast_Score=178, Evalue=3e-44,
Organism=Homo sapiens, GI25777724, Length=463, Percent_Identity=30.4535637149028, Blast_Score=177, Evalue=7e-44,
Organism=Homo sapiens, GI238859541, Length=451, Percent_Identity=30.820399113082, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI21361176, Length=464, Percent_Identity=29.9568965517241, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI153266822, Length=431, Percent_Identity=29.2343387470998, Blast_Score=168, Evalue=3e-41,
Organism=Homo sapiens, GI25777730, Length=458, Percent_Identity=29.6943231441048, Blast_Score=167, Evalue=5e-41,
Organism=Homo sapiens, GI25777728, Length=413, Percent_Identity=30.9927360774818, Blast_Score=163, Evalue=1e-39,
Organism=Homo sapiens, GI25777732, Length=458, Percent_Identity=28.82096069869, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI21614513, Length=423, Percent_Identity=29.5508274231678, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI12007648, Length=434, Percent_Identity=28.110599078341, Blast_Score=153, Evalue=8e-37,
Organism=Homo sapiens, GI238814322, Length=426, Percent_Identity=26.2910798122066, Blast_Score=146, Evalue=1e-34,
Organism=Homo sapiens, GI4507229, Length=422, Percent_Identity=27.2511848341232, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI188035924, Length=444, Percent_Identity=28.1531531531532, Blast_Score=142, Evalue=3e-33,
Organism=Homo sapiens, GI310128103, Length=444, Percent_Identity=28.1531531531532, Blast_Score=141, Evalue=4e-33,
Organism=Homo sapiens, GI310128093, Length=444, Percent_Identity=27.7027027027027, Blast_Score=140, Evalue=6e-33,
Organism=Homo sapiens, GI115387104, Length=435, Percent_Identity=26.4367816091954, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI25777721, Length=435, Percent_Identity=27.1264367816092, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI25777726, Length=461, Percent_Identity=26.4642082429501, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI310128091, Length=390, Percent_Identity=29.2307692307692, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI11095441, Length=425, Percent_Identity=25.6470588235294, Blast_Score=121, Evalue=6e-27,
Organism=Homo sapiens, GI25952152, Length=243, Percent_Identity=31.2757201646091, Blast_Score=109, Evalue=2e-23,
Organism=Homo sapiens, GI310128087, Length=264, Percent_Identity=30.6818181818182, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI206597441, Length=453, Percent_Identity=25.1655629139073, Blast_Score=95, Evalue=6e-19,
Organism=Homo sapiens, GI206597439, Length=453, Percent_Identity=25.1655629139073, Blast_Score=95, Evalue=6e-19,
Organism=Homo sapiens, GI22907049, Length=453, Percent_Identity=25.1655629139073, Blast_Score=95, Evalue=6e-19,
Organism=Homo sapiens, GI4502043, Length=421, Percent_Identity=25.41567695962, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI238814371, Length=421, Percent_Identity=25.41567695962, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI71773324, Length=335, Percent_Identity=26.5671641791045, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI310128089, Length=332, Percent_Identity=28.0120481927711, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI310128095, Length=316, Percent_Identity=28.1645569620253, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI73695881, Length=344, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI73695879, Length=344, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI310128101, Length=211, Percent_Identity=28.9099526066351, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI310128099, Length=199, Percent_Identity=30.1507537688442, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI4557303, Length=382, Percent_Identity=25.3926701570681, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI73466520, Length=382, Percent_Identity=25.3926701570681, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI310128097, Length=264, Percent_Identity=28.030303030303, Blast_Score=78, Evalue=6e-14,
Organism=Escherichia coli, GI1787250, Length=1320, Percent_Identity=91.2878787878788, Blast_Score=2468, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=467, Percent_Identity=30.406852248394, Blast_Score=176, Evalue=1e-44,
Organism=Escherichia coli, GI1788042, Length=440, Percent_Identity=31.3636363636364, Blast_Score=164, Evalue=4e-41,
Organism=Escherichia coli, GI1787715, Length=457, Percent_Identity=30.6345733041575, Blast_Score=160, Evalue=5e-40,
Organism=Escherichia coli, GI1787684, Length=460, Percent_Identity=28.4782608695652, Blast_Score=146, Evalue=1e-35,
Organism=Escherichia coli, GI1787558, Length=416, Percent_Identity=29.3269230769231, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI87082295, Length=436, Percent_Identity=29.3577981651376, Blast_Score=142, Evalue=2e-34,
Organism=Escherichia coli, GI1786504, Length=459, Percent_Identity=27.4509803921569, Blast_Score=141, Evalue=3e-34,
Organism=Escherichia coli, GI87081896, Length=467, Percent_Identity=28.2655246252677, Blast_Score=137, Evalue=7e-33,
Organism=Escherichia coli, GI87081926, Length=455, Percent_Identity=26.8131868131868, Blast_Score=108, Evalue=3e-24,
Organism=Escherichia coli, GI1787653, Length=403, Percent_Identity=22.0843672456576, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17534447, Length=488, Percent_Identity=29.5081967213115, Blast_Score=174, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI133930964, Length=468, Percent_Identity=29.0598290598291, Blast_Score=167, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI25144435, Length=465, Percent_Identity=29.6774193548387, Blast_Score=166, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI115532534, Length=368, Percent_Identity=32.6086956521739, Blast_Score=161, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI115534176, Length=480, Percent_Identity=29.375, Blast_Score=156, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17562198, Length=461, Percent_Identity=29.5010845986985, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32564736, Length=411, Percent_Identity=30.1703163017032, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI25143874, Length=457, Percent_Identity=28.4463894967177, Blast_Score=144, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI25143876, Length=502, Percent_Identity=27.4900398406374, Blast_Score=143, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71986308, Length=461, Percent_Identity=26.6811279826464, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17551164, Length=456, Percent_Identity=26.3157894736842, Blast_Score=132, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32564151, Length=461, Percent_Identity=27.3318872017354, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17534119, Length=463, Percent_Identity=26.5658747300216, Blast_Score=127, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71995606, Length=459, Percent_Identity=25.4901960784314, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71995613, Length=416, Percent_Identity=25.2403846153846, Blast_Score=112, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71990744, Length=299, Percent_Identity=27.4247491638796, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17564084, Length=338, Percent_Identity=25.4437869822485, Blast_Score=90, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI25146391, Length=389, Percent_Identity=22.879177377892, Blast_Score=84, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI32566756, Length=389, Percent_Identity=22.879177377892, Blast_Score=84, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25146394, Length=389, Percent_Identity=22.879177377892, Blast_Score=84, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6321826, Length=540, Percent_Identity=29.6296296296296, Blast_Score=179, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6325196, Length=466, Percent_Identity=29.6137339055794, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6320917, Length=460, Percent_Identity=28.9130434782609, Blast_Score=162, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6323821, Length=472, Percent_Identity=29.4491525423729, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6323822, Length=472, Percent_Identity=29.0254237288136, Blast_Score=159, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6324950, Length=461, Percent_Identity=26.8980477223427, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319478, Length=465, Percent_Identity=28.8172043010753, Blast_Score=134, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6321828, Length=498, Percent_Identity=23.6947791164659, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24668425, Length=482, Percent_Identity=28.2157676348548, Blast_Score=168, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24668417, Length=482, Percent_Identity=28.2157676348548, Blast_Score=168, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24668413, Length=482, Percent_Identity=28.2157676348548, Blast_Score=168, Evalue=3e-41,
Organism=Drosophila melanogaster, GI20129399, Length=466, Percent_Identity=30.4721030042918, Blast_Score=167, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24650465, Length=459, Percent_Identity=27.4509803921569, Blast_Score=160, Evalue=5e-39,
Organism=Drosophila melanogaster, GI281362580, Length=452, Percent_Identity=27.212389380531, Blast_Score=156, Evalue=1e-37,
Organism=Drosophila melanogaster, GI62472918, Length=452, Percent_Identity=27.212389380531, Blast_Score=156, Evalue=1e-37,
Organism=Drosophila melanogaster, GI62472926, Length=452, Percent_Identity=27.212389380531, Blast_Score=156, Evalue=1e-37,
Organism=Drosophila melanogaster, GI62472936, Length=452, Percent_Identity=27.212389380531, Blast_Score=156, Evalue=1e-37,
Organism=Drosophila melanogaster, GI21356737, Length=452, Percent_Identity=27.212389380531, Blast_Score=156, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24585660, Length=447, Percent_Identity=25.503355704698, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28571802, Length=474, Percent_Identity=27.4261603375527, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571800, Length=474, Percent_Identity=27.4261603375527, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571806, Length=474, Percent_Identity=27.4261603375527, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571798, Length=474, Percent_Identity=27.4261603375527, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571796, Length=474, Percent_Identity=27.4261603375527, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571794, Length=474, Percent_Identity=27.4261603375527, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24666674, Length=450, Percent_Identity=29.3333333333333, Blast_Score=136, Evalue=8e-32,
Organism=Drosophila melanogaster, GI28574525, Length=498, Percent_Identity=25.5020080321285, Blast_Score=134, Evalue=6e-31,
Organism=Drosophila melanogaster, GI281360299, Length=386, Percent_Identity=28.4974093264249, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281360297, Length=386, Percent_Identity=28.4974093264249, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281360295, Length=386, Percent_Identity=28.4974093264249, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24586250, Length=386, Percent_Identity=28.4974093264249, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281360301, Length=386, Percent_Identity=28.4974093264249, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45552499, Length=383, Percent_Identity=27.154046997389, Blast_Score=101, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281360303, Length=386, Percent_Identity=27.720207253886, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24638878, Length=394, Percent_Identity=25.8883248730964, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24638876, Length=394, Percent_Identity=25.8883248730964, Blast_Score=99, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 144076; Mature: 143945

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTTTMGVKLDDATRERIKMAASRIDRTPHWLIKQAIFSYLDKLENSDTLPELPALFAGA
CCCCEEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCC
ANESEEPVAPQDEPHQPFLEFAEQILPQSVSRAAITAAWRRPETDAVSMLVEQARLSPPV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCH
AEQAHKLAYQLAEKLRNQKSASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKAT
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHH
RDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGRLVSTHNEANLSRSLNRIIGKSG
HHHHHHHHCCCCCHHHHCCCCCCEEEEHHHHHHHHHCHHHCCCCHHHHHHHHHHHHCCCC
EPLIRKGVDMAMRLMGEQFVTGETIAQALANARKLEEKGFRYSYDMLGEAALTAADAQAY
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHH
MVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLA
HHHHHHHHHHHHCCCCCCCCEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQYDIGLNIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLVDL
HHHCCCCCCCCCCCCHHEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
ASRSRRRLMIRLVKGAYWDSEIKRAQMEGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLI
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHH
YPQFATHNAHTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIY
CCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCCCCCEEEE
APVGTHETLLAYLVRRLLENGANTSFVNRIADATLPLDELVADPVEAVEKLAQQEGQAGI
ECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHCCCCCC
PHPKIPLPRDLYGEGRINSAGLDLANEHRLASLSSALLSNAMQKWQAKPVLEQPVADGEM
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCC
TPVINPAEPKDIVGWGREATESEVEQALQNAVNQAPVWFATPPQERAAILQRAAVLMEDQ
CCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHH
MQQLIGLLVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFDNETHRPLGPVVCISPWNF
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCC
PLAIFTGQIAAALAAGNSVLAKPAEQTSLIAAQGIAILLEAGVPPGVVQLLPGRGETVGA
CHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHCCHHEEEECCCCCCHHEECCCCCCCCCC
QLTADARVRGVMFTGSTEVATLLQRNIATRLDAQGRPIPLIAETGGMNAMIVDSSALTEQ
EEEECCEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCHHHHHH
VVVDVLASAFDSAGQRCSALRVLCLQDDIAEHTLKMLRGAMAECRMGNPGRLTTDIGPVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC
DSEAKANIERHIQTMRAKGRPVFQAARENNDDAQEWQTGTFVMPTLIELENFAELEKEVF
CCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHH
GPVLHVVRYNRNQLAELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVG
HHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCEECEEEECCCCEE
AVVGVQPFGGEGLSGTGPKAGGPLYLYRLLAHRPPNALNTTLTRQDARYPVDAQLKTTLL
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCHHHHHHH
APLTALTQWAADRPALQTLCRQFADLAQAGTQRLLPGPTGERNTWTLLPRERVLCLADDE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEECCC
QDALTQLAAVLAVGSQALWSDDAFHRDLAKRLPAAVAARVQFAKAETLMAQPFDAVIFHG
HHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
DSDKLRTVCEAVAAREGAIVSVQGFARGESNMLLERLYIERSLSVNTAAAGGNASLMTIG
CCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEEC
>Mature Secondary Structure 
GTTTMGVKLDDATRERIKMAASRIDRTPHWLIKQAIFSYLDKLENSDTLPELPALFAGA
CCCEEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCC
ANESEEPVAPQDEPHQPFLEFAEQILPQSVSRAAITAAWRRPETDAVSMLVEQARLSPPV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCH
AEQAHKLAYQLAEKLRNQKSASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKAT
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHH
RDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGRLVSTHNEANLSRSLNRIIGKSG
HHHHHHHHCCCCCHHHHCCCCCCEEEEHHHHHHHHHCHHHCCCCHHHHHHHHHHHHCCCC
EPLIRKGVDMAMRLMGEQFVTGETIAQALANARKLEEKGFRYSYDMLGEAALTAADAQAY
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHH
MVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLA
HHHHHHHHHHHHCCCCCCCCEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQYDIGLNIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLVDL
HHHCCCCCCCCCCCCHHEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
ASRSRRRLMIRLVKGAYWDSEIKRAQMEGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLI
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHH
YPQFATHNAHTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIY
CCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCCCCCEEEE
APVGTHETLLAYLVRRLLENGANTSFVNRIADATLPLDELVADPVEAVEKLAQQEGQAGI
ECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHCCCCCC
PHPKIPLPRDLYGEGRINSAGLDLANEHRLASLSSALLSNAMQKWQAKPVLEQPVADGEM
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCC
TPVINPAEPKDIVGWGREATESEVEQALQNAVNQAPVWFATPPQERAAILQRAAVLMEDQ
CCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHH
MQQLIGLLVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFDNETHRPLGPVVCISPWNF
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCC
PLAIFTGQIAAALAAGNSVLAKPAEQTSLIAAQGIAILLEAGVPPGVVQLLPGRGETVGA
CHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHCCHHEEEECCCCCCHHEECCCCCCCCCC
QLTADARVRGVMFTGSTEVATLLQRNIATRLDAQGRPIPLIAETGGMNAMIVDSSALTEQ
EEEECCEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCHHHHHH
VVVDVLASAFDSAGQRCSALRVLCLQDDIAEHTLKMLRGAMAECRMGNPGRLTTDIGPVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC
DSEAKANIERHIQTMRAKGRPVFQAARENNDDAQEWQTGTFVMPTLIELENFAELEKEVF
CCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHH
GPVLHVVRYNRNQLAELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVG
HHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCEECEEEECCCCEE
AVVGVQPFGGEGLSGTGPKAGGPLYLYRLLAHRPPNALNTTLTRQDARYPVDAQLKTTLL
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCHHHHHHH
APLTALTQWAADRPALQTLCRQFADLAQAGTQRLLPGPTGERNTWTLLPRERVLCLADDE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEECCC
QDALTQLAAVLAVGSQALWSDDAFHRDLAKRLPAAVAARVQFAKAETLMAQPFDAVIFHG
HHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
DSDKLRTVCEAVAAREGAIVSVQGFARGESNMLLERLYIERSLSVNTAAAGGNASLMTIG
CCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]