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The map label for this gene is qseC [H]

Identifier: 194737085

GI number: 194737085

Start: 3247690

End: 3249039

Strand: Direct

Name: qseC [H]

Synonym: SeSA_A3363

Alternate gene names: 194737085

Gene position: 3247690-3249039 (Clockwise)

Preceding gene: 194736474

Following gene: 194735874

Centisome position: 68.97

GC content: 56.52

Gene sequence:

>1350_bases
ATGAAATTGACGCAACGTCTCAGCCTGCGCGTCAGGCTGACGCTTATTTTTCTGATTCTGGTCTCCATCACCTGGGCAAT
CTCCAGTTTTGTGGCCTGGAGAAAGACGACGGATAATGTCGACGAGCTGTTTGACACACAGTTGATGTTGTTCGCCAGAC
GGCTTAGCACCCTCGATCTTAACGAGATCAACGCCCCGCAGCGCATGGCGCATACGCCAAAGAAATTAAAACATGGGCAT
ATCGATGACGATGCGCTGGCATTCGCCATCTTTTCCGCTGACGGCAAAATGTTGCTGCATGATGGCGACAACGGCCAGGA
TATTCCGTATCGCTATCGCCGCGAAGGTTTCGACAATGGCTATCTGAAGGATGACAACGATCTCTGGCGTTTTTTGTGGT
TGAACTCGGCGGACGGTAAGTATCGTATCGTCGTCGGTCAGGAGTGGGATTACCGCGAAGATATGGCGCTGGCGATCGTG
GCGGCGCAATTAACGCCGTGGCTGCTCGCCCTTCCCTTCATGCTACTGATTTTATTACTCCTGCTTCACCGCGAGCTCAG
ACCGTTGAAAAAACTGGCGCAGGCGCTGCGCTTCCGGTCGCCGGAATCGGAAACGCCGCTCGACGCCAAAGGCGTACCGA
GCGAGGTTCGCCCACTGGTCGAAGCGCTTAATCAGCTTTTTAGCCGCATCCACTCCATGATGGTGCGCGAACGGCGATTT
ACCTCCGACGCTGCCCATGAATTGCGCAGCCCGCTGGCCGCGCTGAAAGTACAAACCGAGGTGGCGCAGCTCTCGGGCGA
CGATCCGCTCTCACGCGATAAAGCGCTGACCCAGCTCCATGCGGGGATCGATCGCGCCACGCGGCTGGTCGATCAGCTAC
TGACATTATCGCGCCTCGACTCGCTCAATAATTTGCAGGATGTGGCGGAGATTTCGCTGGAAGAGCTGCTGCAGTCCGCG
GTAATGGATATTTATCATCCGGCGCAGCAGGCGAATATCGACGTGCGTTTACAGCTTAACGCCCATGACGTCATACGTAC
CGGCCAGCCGCTACTCTTAAGCCTGTTAGTGCGTAACCTGCTGGATAATGCGATTCGCTACAGTCCGCAGGGCAGCGTCG
TCGACGTTACCTTACATGCCCGCAGCTTCACCGTCAGAGATAATGGCCCTGGCGTAGCGCCAGAGATTCTGACGCATATC
GGCGAGCGTTTTTACCGCCCGCCTGGCCAAAGTGTGACCGGCAGCGGTCTGGGATTATCAATCGTCCGCCGCATCGCTAC
GCTGCACGGCATGACGGTGTCGTTTGGCAACGCCGCGGAAGGTGGATTTGAGGCCGTAGTACGCTGGTAG

Upstream 100 bases:

>100_bases
CCAGCAATGCAGTGGAAGTCCATGTTCATCATTTACGCCGCAAGCTCGGCAGTGAATTTATTCGCACCGTACACGGCATC
GGCTATACCCTGGGTGACGC

Downstream 100 bases:

>100_bases
CAGAGATTTTTGCCAAAAACGCAAAAGACTTTGCACATTTTGCTAATTTCACCGCACCGCCCGTCAGCGTAGAATCAGCA
GCAAACGCATTTCTTGAGGA

Product: sensor protein QseC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDLNEINAPQRMAHTPKKLKHGH
IDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNGYLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIV
AAQLTPWLLALPFMLLILLLLLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLDSLNNLQDVAEISLEELLQSA
VMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHI
GERFYRPPGQSVTGSGLGLSIVRRIATLHGMTVSFGNAAEGGFEAVVRW

Sequences:

>Translated_449_residues
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDLNEINAPQRMAHTPKKLKHGH
IDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNGYLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIV
AAQLTPWLLALPFMLLILLLLLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLDSLNNLQDVAEISLEELLQSA
VMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHI
GERFYRPPGQSVTGSGLGLSIVRRIATLHGMTVSFGNAAEGGFEAVVRW
>Mature_449_residues
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDLNEINAPQRMAHTPKKLKHGH
IDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNGYLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIV
AAQLTPWLLALPFMLLILLLLLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLDSLNNLQDVAEISLEELLQSA
VMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHI
GERFYRPPGQSVTGSGLGLSIVRRIATLHGMTVSFGNAAEGGFEAVVRW

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=449, Percent_Identity=79.0645879732739, Blast_Score=711, Evalue=0.0,
Organism=Escherichia coli, GI1790551, Length=297, Percent_Identity=33.6700336700337, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786783, Length=350, Percent_Identity=28, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788279, Length=263, Percent_Identity=28.5171102661597, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1787894, Length=236, Percent_Identity=30.5084745762712, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1786600, Length=214, Percent_Identity=29.9065420560748, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=31.6872427983539, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786912, Length=236, Percent_Identity=31.3559322033898, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=256, Percent_Identity=30.859375, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790346, Length=242, Percent_Identity=29.7520661157025, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789808, Length=289, Percent_Identity=27.681660899654, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50608; Mature: 50608

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
NEINAPQRMAHTPKKLKHGHIDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNG
HHCCCCHHHHCCHHHHCCCCCCCHHHEEEEEECCCEEEEECCCCCCCCCHHHHHCCCCCC
YLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIVAAQLTPWLLALPFMLLILLL
CCCCCCCEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLD
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLNNLQDVAEISLEELLQSAVMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEEEECHHHHHHCCHHHHHHHHHHHH
LDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHIGERFYRPPGQSVTGSGLGLS
HHHHHHCCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHH
IVRRIATLHGMTVSFGNAAEGGFEAVVRW
HHHHHHHHHCCEEECCCCCCCCHHHHCCC
>Mature Secondary Structure
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
NEINAPQRMAHTPKKLKHGHIDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNG
HHCCCCHHHHCCHHHHCCCCCCCHHHEEEEEECCCEEEEECCCCCCCCCHHHHHCCCCCC
YLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIVAAQLTPWLLALPFMLLILLL
CCCCCCCEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLD
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLNNLQDVAEISLEELLQSAVMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEEEECHHHHHHCCHHHHHHHHHHHH
LDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHIGERFYRPPGQSVTGSGLGLS
HHHHHHCCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHH
IVRRIATLHGMTVSFGNAAEGGFEAVVRW
HHHHHHHHHCCEEECCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]