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The map label for this gene is btuB [H]

Identifier: 194736845

GI number: 194736845

Start: 4215322

End: 4217166

Strand: Direct

Name: btuB [H]

Synonym: SeSA_A4341

Alternate gene names: 194736845

Gene position: 4215322-4217166 (Clockwise)

Preceding gene: 194735615

Following gene: 194738355

Centisome position: 89.51

GC content: 51.87

Gene sequence:

>1845_bases
ATGATTAAAAAAGCTACGCTGCTGACGGCGTTCTCCGTCACGGCCTTTTCCGCTTGGGCGCAGGACACTAGCCCGGATAC
CCTGGTTGTCACCGCCAACCGTTTTCAGCAGCCGCGCAGCGCGGTTCTGGCGCCCGTTACCATCGTGACGCGTCAGGATA
TTGAACGCTGGCAATCGACCTCCGTAAATGATGTTCTGCGCCGTTTGCCTGGCGTCGATATTGCGCAGAGCGGCGGCGCC
GGACAAAACTCCTCCATTTTCATTCGCGGCACCAACTCCAGCCATGTACTGGTATTGATTGACGGCGTGCGTCTGAATTT
AGCAGGCGTGAGCGGGTCCGCCGATCTCAGCCAGTTCCCGGTGTCGCTGGTACAGCGCATTGAATATATTCGCGGTCCGC
GCTCCGCTATTTATGGTTCCGATGCTATCGGCGGCGTAGTGAATATCATTACGACGCGCGATAACCCAGGCACAGAATTA
ACCGCTGGGTGGGGAAGCAATAGCTACCAGAATTACGACATCTCGACGCAACAGCAACTTGGCGAAAACACGCGGGCGAC
GTTGATCGGCGATTACGAATACACCAAAGGGTTTGACGTGGTAGCGAAAGGCGGTACCGGGATGCAGGCGCAGCCTGACC
GGGACGGCTTTTTGAGTAAAACGCTTTATGGCGCGTTAGAGCATACCTTTTCTGAGCGCTGGAGCGGATTCGTGCGTGGT
TATGGCTACGATAACCGTACCGATTACGACGCCTATTACTCGCCGGGCTCGCCGCTGATTGATACACGCAAACTTTATAG
CCAAAGCTGGGACGCCGGGCTGCGCTTTAATGGCGAACGTATTCAGTCTCAGCTGGTTTCAAGCTATAGCCACAGTAAAG
ATTACAACTATGATCCGCACTATGGCCGGTATGATACCTCCGCCACGCTGGATGAGATGAAACAGTACAATGTTCAATGG
ACCAACAGTGTGGTCGTGGGGCACGGTAATGTTGGGGCGGGCGTAGACTGGCAGAAACAGACTACCACGCCAGGTACCGG
CTATGTGCCCGAGGGATATGACCAGCGTAATACTGGGGTTTACCTGACAGGATTACAACAATTGGGTGACTTCACTCTGG
AAGCGGCGGCGCGCAGTGATGACAACTCCCAGTTTGGTCGTCATGGTACATGGCAAACCAGCGCGGGATGGGAGTTTATA
GAAGGTTATCGCTTTATTGCCTCCTACGGAACCTCCTACAAAGCGCCTAATTTGGGCCAACTGTATGGTTATTATGGTAA
TCCGAACCTGAATCCTGAAAAGAGTAAACAGTGGGAAGGCGCATTTGAAGGGCTAACCGCTGGCGTCAGCTGGCGTATTT
CAGGTTATCGTAACGATATTAATGACATGATCGATTATGACGATCATCTGCAAAAATATTACAACGAAGGCAAGGCGCGC
ATTAAAGGTATTGAGGCGACGGCGAATTTCGATACCGGACCGTTAACGCATACGGTCAGTTATGATTACGTTGATGCGCG
TAATGCGATTACTGATACGCCATTACCCCGGCGTTCCAAACAGATGGCAAAATATCAACTTGACTGGGACGTTTACGATT
TTGACTGGGGGGTGACATATCAATACCTTGGTTCCCGCTATGATTCGGACTACTCCGCTTACCCATACCGGACAGTAAAA
ATGGGCGGCGTCAGTTTATGGGATCTTACGGTTGCATATCCGGTCACCTCACATCTGACAGTTCGTGGTAAAATAGCCAA
CCTGTTCGACAAAGATTACGAGACAGTTTATGGCTACCAAACTGCAGGACGAGAATACACCTTGTCTGGCAGCTACACCT
TCTGA

Upstream 100 bases:

>100_bases
AAGCCCGAAGACCTGCCGGCTAACGTCGCATCTGGTTTTTCATCATCGCGTACTATCGATGAAGCCTGCGGCATCCTTCT
TATATTGTGGATGCTTTACA

Downstream 100 bases:

>100_bases
ACCACGTCCCACCGTGCTGGTATTTGATTCCGGCGTCGGTGGATTGTCGGTCTATGATGAGATTCGGCGGCTCCTGCCGG
ATCTCCACTATATATATGCT

Product: vitamin B12/cobalamin outer membrane transporter

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MIKKATLLTAFSVTAFSAWAQDTSPDTLVVTANRFQQPRSAVLAPVTIVTRQDIERWQSTSVNDVLRRLPGVDIAQSGGA
GQNSSIFIRGTNSSHVLVLIDGVRLNLAGVSGSADLSQFPVSLVQRIEYIRGPRSAIYGSDAIGGVVNIITTRDNPGTEL
TAGWGSNSYQNYDISTQQQLGENTRATLIGDYEYTKGFDVVAKGGTGMQAQPDRDGFLSKTLYGALEHTFSERWSGFVRG
YGYDNRTDYDAYYSPGSPLIDTRKLYSQSWDAGLRFNGERIQSQLVSSYSHSKDYNYDPHYGRYDTSATLDEMKQYNVQW
TNSVVVGHGNVGAGVDWQKQTTTPGTGYVPEGYDQRNTGVYLTGLQQLGDFTLEAAARSDDNSQFGRHGTWQTSAGWEFI
EGYRFIASYGTSYKAPNLGQLYGYYGNPNLNPEKSKQWEGAFEGLTAGVSWRISGYRNDINDMIDYDDHLQKYYNEGKAR
IKGIEATANFDTGPLTHTVSYDYVDARNAITDTPLPRRSKQMAKYQLDWDVYDFDWGVTYQYLGSRYDSDYSAYPYRTVK
MGGVSLWDLTVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF

Sequences:

>Translated_614_residues
MIKKATLLTAFSVTAFSAWAQDTSPDTLVVTANRFQQPRSAVLAPVTIVTRQDIERWQSTSVNDVLRRLPGVDIAQSGGA
GQNSSIFIRGTNSSHVLVLIDGVRLNLAGVSGSADLSQFPVSLVQRIEYIRGPRSAIYGSDAIGGVVNIITTRDNPGTEL
TAGWGSNSYQNYDISTQQQLGENTRATLIGDYEYTKGFDVVAKGGTGMQAQPDRDGFLSKTLYGALEHTFSERWSGFVRG
YGYDNRTDYDAYYSPGSPLIDTRKLYSQSWDAGLRFNGERIQSQLVSSYSHSKDYNYDPHYGRYDTSATLDEMKQYNVQW
TNSVVVGHGNVGAGVDWQKQTTTPGTGYVPEGYDQRNTGVYLTGLQQLGDFTLEAAARSDDNSQFGRHGTWQTSAGWEFI
EGYRFIASYGTSYKAPNLGQLYGYYGNPNLNPEKSKQWEGAFEGLTAGVSWRISGYRNDINDMIDYDDHLQKYYNEGKAR
IKGIEATANFDTGPLTHTVSYDYVDARNAITDTPLPRRSKQMAKYQLDWDVYDFDWGVTYQYLGSRYDSDYSAYPYRTVK
MGGVSLWDLTVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF
>Mature_614_residues
MIKKATLLTAFSVTAFSAWAQDTSPDTLVVTANRFQQPRSAVLAPVTIVTRQDIERWQSTSVNDVLRRLPGVDIAQSGGA
GQNSSIFIRGTNSSHVLVLIDGVRLNLAGVSGSADLSQFPVSLVQRIEYIRGPRSAIYGSDAIGGVVNIITTRDNPGTEL
TAGWGSNSYQNYDISTQQQLGENTRATLIGDYEYTKGFDVVAKGGTGMQAQPDRDGFLSKTLYGALEHTFSERWSGFVRG
YGYDNRTDYDAYYSPGSPLIDTRKLYSQSWDAGLRFNGERIQSQLVSSYSHSKDYNYDPHYGRYDTSATLDEMKQYNVQW
TNSVVVGHGNVGAGVDWQKQTTTPGTGYVPEGYDQRNTGVYLTGLQQLGDFTLEAAARSDDNSQFGRHGTWQTSAGWEFI
EGYRFIASYGTSYKAPNLGQLYGYYGNPNLNPEKSKQWEGAFEGLTAGVSWRISGYRNDINDMIDYDDHLQKYYNEGKAR
IKGIEATANFDTGPLTHTVSYDYVDARNAITDTPLPRRSKQMAKYQLDWDVYDFDWGVTYQYLGSRYDSDYSAYPYRTVK
MGGVSLWDLTVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG4206

COG function: function code H; Outer membrane cobalamin receptor protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=614, Percent_Identity=87.2964169381108, Blast_Score=1126, Evalue=0.0,
Organism=Escherichia coli, GI1788478, Length=701, Percent_Identity=25.962910128388, Blast_Score=165, Evalue=9e-42,
Organism=Escherichia coli, GI1786798, Length=715, Percent_Identity=24.3356643356643, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1787024, Length=207, Percent_Identity=26.5700483091787, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 68527; Mature: 68527

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00430 TONB_DEPENDENT_REC_1 ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKATLLTAFSVTAFSAWAQDTSPDTLVVTANRFQQPRSAVLAPVTIVTRQDIERWQST
CCCCEEEEEHHHHHHHHHHCCCCCCCEEEEECHHCCCCCHHHCCEEEEEEHHHHHHHHCC
SVNDVLRRLPGVDIAQSGGAGQNSSIFIRGTNSSHVLVLIDGVRLNLAGVSGSADLSQFP
CHHHHHHHCCCCCEECCCCCCCCCEEEEEECCCCEEEEEEECEEEEEEECCCCCCHHHHH
VSLVQRIEYIRGPRSAIYGSDAIGGVVNIITTRDNPGTELTAGWGSNSYQNYDISTQQQL
HHHHHHHHHHCCCCHHCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCCHHHHC
GENTRATLIGDYEYTKGFDVVAKGGTGMQAQPDRDGFLSKTLYGALEHTFSERWSGFVRG
CCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHEEE
YGYDNRTDYDAYYSPGSPLIDTRKLYSQSWDAGLRFNGERIQSQLVSSYSHSKDYNYDPH
CCCCCCCCCCCEECCCCCCCHHHHHHHCCCCCCCEECHHHHHHHHHHHHHCCCCCCCCCC
YGRYDTSATLDEMKQYNVQWTNSVVVGHGNVGAGVDWQKQTTTPGTGYVPEGYDQRNTGV
CCCCCCCHHHHHHHHCCCEEECEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
YLTGLQQLGDFTLEAAARSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYKAPNLGQ
EEEEHHHHCCCCEEHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
LYGYYGNPNLNPEKSKQWEGAFEGLTAGVSWRISGYRNDINDMIDYDDHLQKYYNEGKAR
EEEEECCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEE
IKGIEATANFDTGPLTHTVSYDYVDARNAITDTPLPRRSKQMAKYQLDWDVYDFDWGVTY
EEEEEEECCCCCCCCEEEEEECEECCCCCCCCCCCCCHHHHHHEEEECCEEEECCCCCCH
QYLGSRYDSDYSAYPYRTVKMGGVSLWDLTVAYPVTSHLTVRGKIANLFDKDYETVYGYQ
HHHCCCCCCCCCCCCEEEEEECCEEEEEEEEEEECCCEEEEEEHHHHHHCCCCHHEEEEE
TAGREYTLSGSYTF
CCCCEEEECCCCCC
>Mature Secondary Structure
MIKKATLLTAFSVTAFSAWAQDTSPDTLVVTANRFQQPRSAVLAPVTIVTRQDIERWQST
CCCCEEEEEHHHHHHHHHHCCCCCCCEEEEECHHCCCCCHHHCCEEEEEEHHHHHHHHCC
SVNDVLRRLPGVDIAQSGGAGQNSSIFIRGTNSSHVLVLIDGVRLNLAGVSGSADLSQFP
CHHHHHHHCCCCCEECCCCCCCCCEEEEEECCCCEEEEEEECEEEEEEECCCCCCHHHHH
VSLVQRIEYIRGPRSAIYGSDAIGGVVNIITTRDNPGTELTAGWGSNSYQNYDISTQQQL
HHHHHHHHHHCCCCHHCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCCHHHHC
GENTRATLIGDYEYTKGFDVVAKGGTGMQAQPDRDGFLSKTLYGALEHTFSERWSGFVRG
CCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHEEE
YGYDNRTDYDAYYSPGSPLIDTRKLYSQSWDAGLRFNGERIQSQLVSSYSHSKDYNYDPH
CCCCCCCCCCCEECCCCCCCHHHHHHHCCCCCCCEECHHHHHHHHHHHHHCCCCCCCCCC
YGRYDTSATLDEMKQYNVQWTNSVVVGHGNVGAGVDWQKQTTTPGTGYVPEGYDQRNTGV
CCCCCCCHHHHHHHHCCCEEECEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
YLTGLQQLGDFTLEAAARSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYKAPNLGQ
EEEEHHHHCCCCEEHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
LYGYYGNPNLNPEKSKQWEGAFEGLTAGVSWRISGYRNDINDMIDYDDHLQKYYNEGKAR
EEEEECCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEE
IKGIEATANFDTGPLTHTVSYDYVDARNAITDTPLPRRSKQMAKYQLDWDVYDFDWGVTY
EEEEEEECCCCCCCCEEEEEECEECCCCCCCCCCCCCHHHHHHEEEECCEEEECCCCCCH
QYLGSRYDSDYSAYPYRTVKMGGVSLWDLTVAYPVTSHLTVRGKIANLFDKDYETVYGYQ
HHHCCCCCCCCCCCCEEEEEECCEEEEEEEEEEECCCEEEEEEHHHHHHCCCCHHEEEEE
TAGREYTLSGSYTF
CCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA