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The map label for this gene is laaA [H]

Identifier: 194736795

GI number: 194736795

Start: 1427073

End: 1427966

Strand: Reverse

Name: laaA [H]

Synonym: SeSA_A1477

Alternate gene names: 194736795

Gene position: 1427966-1427073 (Counterclockwise)

Preceding gene: 194735500

Following gene: 194734175

Centisome position: 30.32

GC content: 51.34

Gene sequence:

>894_bases
ATGAATGATACTTATCTCTATGGCGAAATGTTTTCTGAAAACATATTGACAAGCTATCGGATTTATGGAGACAGAAAATC
ATTACTCACGCCGCTCATTATCCTTCACGGCGGCCCTTCTGGCGGCTTTGATTATTTATTAAATTATCGCCATCTGGCTG
ATGACGGGCGCATGGTAATATTTTACGATCAATATGGCTGCGGTCGTTCAACGCATTTTCCTCATGCCGACGCGTCTTTC
TGGACTATTGCGCGTTATCTCCGTCAATTAACCCAATTAATTCATCACCTGGGTATTGGGCACGGGTATTCGATACTGGG
ACATTCCTGGGGCGGAATGCTTGCCGCAGAGCACGCCTGCTTACAGCCTGCCGGGCTTCGCGGGACGATACTGGCCAGTT
CGCCGGCCAGTATCGCCCTGTGGCAACAGGAAGCCATACGGCTCTTTAACGCTCTGACGCCAATGTCCGATGACGATATC
AAAAACGTCATTATGCCCGCCGTCATTTATCAAAACCCACCGGAACAGCTGGTCGCTTATTATGCCAGACACGTTTATAC
CCTCGCGGAAGAAGCCGTTCATGTTCAGCGATCTAATGCGCAGTTCGCCGCCGACCCTACGGGTTATCACATTTTATGGG
GAACCAATGAACTGGCGGCAAATGGCAAACTTGCCGACTGGAATATTACGCCCCATTTGTGCCAGATACGCTGTCCTGTT
CTGGTACTGCGCGGCGAAAACGATCAGGCAACCGAGCGCGTCGTCTCTCCGCTGCTCTCTCACATTTCAGACTGCCGCGC
GGTCACTATTCCCGGCAGCAGCCATAACCCGCATGAAGAAAATATCGCGCCCTGCCTCGCAGCGGTAAGCGCGTTTTTAC
GCGATCTGGCATAA

Upstream 100 bases:

>100_bases
GCCACCTTCTGGTGTAATCTTTTACACACAATAAAAAAATAATATTACCCAGGCGAATATAAATTTCGCCTGCCCTGCCA
CACACTGAGTCATTAAGAAT

Downstream 100 bases:

>100_bases
AAAGCCATTAAGGTATTTATCATGAAAAAAGTCAAAAAATTGTCTCTTACCGATTTAGTGCTTTATGGTCTGGTGTTTAT
GGTGCCTATCGCGCCAGTCT

Product: proline iminopeptidase like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNDTYLYGEMFSENILTSYRIYGDRKSLLTPLIILHGGPSGGFDYLLNYRHLADDGRMVIFYDQYGCGRSTHFPHADASF
WTIARYLRQLTQLIHHLGIGHGYSILGHSWGGMLAAEHACLQPAGLRGTILASSPASIALWQQEAIRLFNALTPMSDDDI
KNVIMPAVIYQNPPEQLVAYYARHVYTLAEEAVHVQRSNAQFAADPTGYHILWGTNELAANGKLADWNITPHLCQIRCPV
LVLRGENDQATERVVSPLLSHISDCRAVTIPGSSHNPHEENIAPCLAAVSAFLRDLA

Sequences:

>Translated_297_residues
MNDTYLYGEMFSENILTSYRIYGDRKSLLTPLIILHGGPSGGFDYLLNYRHLADDGRMVIFYDQYGCGRSTHFPHADASF
WTIARYLRQLTQLIHHLGIGHGYSILGHSWGGMLAAEHACLQPAGLRGTILASSPASIALWQQEAIRLFNALTPMSDDDI
KNVIMPAVIYQNPPEQLVAYYARHVYTLAEEAVHVQRSNAQFAADPTGYHILWGTNELAANGKLADWNITPHLCQIRCPV
LVLRGENDQATERVVSPLLSHISDCRAVTIPGSSHNPHEENIAPCLAAVSAFLRDLA
>Mature_297_residues
MNDTYLYGEMFSENILTSYRIYGDRKSLLTPLIILHGGPSGGFDYLLNYRHLADDGRMVIFYDQYGCGRSTHFPHADASF
WTIARYLRQLTQLIHHLGIGHGYSILGHSWGGMLAAEHACLQPAGLRGTILASSPASIALWQQEAIRLFNALTPMSDDDI
KNVIMPAVIYQNPPEQLVAYYARHVYTLAEEAVHVQRSNAQFAADPTGYHILWGTNELAANGKLADWNITPHLCQIRCPV
LVLRGENDQATERVVSPLLSHISDCRAVTIPGSSHNPHEENIAPCLAAVSAFLRDLA

Specific function: Hydrolyzes L-prolinamide, L-proline-p-nitroanilide, L- alaninamide, L-methioninamide, piperidine-2-carboxamide and piperazine-2-carboxamide. Has a much lower activity towards piperazine-2-tert-butylcarboxamide. Does not hydrolyze dipeptides and D-prolinam

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005945
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.5.1.101 [H]

Molecular weight: Translated: 32950; Mature: 32950

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTYLYGEMFSENILTSYRIYGDRKSLLTPLIILHGGPSGGFDYLLNYRHLADDGRMVI
CCCCEEEHHHHHHHHHHHEEEECCHHHHHCEEEEEECCCCCCHHHHHHHHEECCCCCEEE
FYDQYGCGRSTHFPHADASFWTIARYLRQLTQLIHHLGIGHGYSILGHSWGGMLAAEHAC
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHH
LQPAGLRGTILASSPASIALWQQEAIRLFNALTPMSDDDIKNVIMPAVIYQNPPEQLVAY
CCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHH
YARHVYTLAEEAVHVQRSNAQFAADPTGYHILWGTNELAANGKLADWNITPHLCQIRCPV
HHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCCHHCCCCCEEECCCCCCCEEEECCE
LVLRGENDQATERVVSPLLSHISDCRAVTIPGSSHNPHEENIAPCLAAVSAFLRDLA
EEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNDTYLYGEMFSENILTSYRIYGDRKSLLTPLIILHGGPSGGFDYLLNYRHLADDGRMVI
CCCCEEEHHHHHHHHHHHEEEECCHHHHHCEEEEEECCCCCCHHHHHHHHEECCCCCEEE
FYDQYGCGRSTHFPHADASFWTIARYLRQLTQLIHHLGIGHGYSILGHSWGGMLAAEHAC
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHH
LQPAGLRGTILASSPASIALWQQEAIRLFNALTPMSDDDIKNVIMPAVIYQNPPEQLVAY
CCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHH
YARHVYTLAEEAVHVQRSNAQFAADPTGYHILWGTNELAANGKLADWNITPHLCQIRCPV
HHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCCHHCCCCCEEECCCCCCCEEEECCE
LVLRGENDQATERVVSPLLSHISDCRAVTIPGSSHNPHEENIAPCLAAVSAFLRDLA
EEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA