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The map label for this gene is eutG [H]

Identifier: 194736764

GI number: 194736764

Start: 2571762

End: 2572949

Strand: Reverse

Name: eutG [H]

Synonym: SeSA_A2695

Alternate gene names: 194736764

Gene position: 2572949-2571762 (Counterclockwise)

Preceding gene: 194736322

Following gene: 194735021

Centisome position: 54.64

GC content: 62.63

Gene sequence:

>1188_bases
ATGCAAGCTGAACTACAGACGGCGCTGTTTCAGGCATTCGACACCCTGAATCTGCAACGGGTGAAAACGTTCAGCGTACC
GCCGGTCACGCTGTGCGGGCTTGGGGCGCTCGGCGCCTGCGGCCAGGAAGCGCAAGCGCGAGGCGTAAGCCATCTGTTTG
TGATGGTCGACAGCTTCCTGCATCAGGCGGGAATGACTGCGCCGCTGGCACGCAGCTTGGCGATGAAAGGCGTGGCGATG
ACAGTCTGGCCGTGTCCGCCAGGCGAGCCGTGCATTACCGATGTCTGCGCGGCGGTGGCGCAACTGCGTGAGGCGGCGTG
CGACGGCGTAGTGGCCTTTGGCGGCGGTTCGGTGCTGGACGCGGCGAAAGCGGTCGCCCTGCTGGTGACTAACCCTGACC
AGACGCTGAGCGCCATGACCGAGCGCAGTACATTACGCCCGCGTCTGCCGCTGATTGCGGTGCCGACCACCGCCGGAACC
GGTTCTGAAACCACCAACGTGACGGTGATTATCGACGCGGTCAGCGGGCGCAAGCAGGTGCTGGCGCACGCGTCACTAAT
GCCGGACGTGGCGATTCTTGATGCTGCCGTGACCGAAGGCGTTCCGCCAAACGTGACGGCGATGACCGGTATCGATGCGT
TGACTCATGCGATTGAGGCCTACAGCGCGCTCAACGCCACGCCGTTTACCGACAGCCTGGCGATTGGCGCGATAGCGATG
ATTGGCAAATCGCTGCCGAAAGCCGTGGGTTACGGCCACGATCTGGCGGCGCGTGAAAATATGTTACTGGCCTCCTGTAT
GGCGGGAATGGCCTTTTCCAGCGCCGGTCTGGGGCTGTGTCATGCAATGGCGCACCAGCCAGGGGCGGCGCTGCATATTC
CGCACGGCCAGGCCAACGCTATGCTGCTGCCAACGGTCATGGGCTTTAACCGGATGGTATGCCGCGAACGCTTCAGTCAA
ATCGGCCGGGCGTTAACCAATAAGAAATCGGACGATCGCGATGCGATTGCGGCGGTGAGCGAGCTGATTGCCGAAGTAGG
GCAGAGCAAACGGCTGGCTGACGCTGGCGCCAAACCCGAACACTACAGCGCATGGGCGCAAGCCGCGCTGGAGGATATTT
GTCTGCGCAGTAACCCACGCACCGCCACACAGGCACAGATTATCGACCTGTACGCGGCTGCCGGGTAA

Upstream 100 bases:

>100_bases
CAGCGTTTCCCGGAGTTACAGGTGCATTTACCACAGCACAGCCTGTTTATGACCCCGCTGGCGATAGCTAACAGCGGGAG
AGCGAAAGCGGAGGGACTCT

Downstream 100 bases:

>100_bases
TGCCTGTAGGCCGGATAAGGTGCTCGCACCGCCATCCGGCAATAACACGGCGTTAATGCCGGAGGCGACGTAAACGTCTT
ATCCGGCCTACAAATCATAA

Product: ethanolamine utilization protein EutG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MQAELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFLHQAGMTAPLARSLAMKGVAM
TVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLDAAKAVALLVTNPDQTLSAMTERSTLRPRLPLIAVPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANAMLLPTVMGFNRMVCRERFSQ
IGRALTNKKSDDRDAIAAVSELIAEVGQSKRLADAGAKPEHYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG

Sequences:

>Translated_395_residues
MQAELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFLHQAGMTAPLARSLAMKGVAM
TVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLDAAKAVALLVTNPDQTLSAMTERSTLRPRLPLIAVPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANAMLLPTVMGFNRMVCRERFSQ
IGRALTNKKSDDRDAIAAVSELIAEVGQSKRLADAGAKPEHYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG
>Mature_395_residues
MQAELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFLHQAGMTAPLARSLAMKGVAM
TVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLDAAKAVALLVTNPDQTLSAMTERSTLRPRLPLIAVPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANAMLLPTVMGFNRMVCRERFSQ
IGRALTNKKSDDRDAIAAVSELIAEVGQSKRLADAGAKPEHYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG

Specific function: May act on the acetaldehyde produced from the degradation of ethanolamine [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=323, Percent_Identity=28.7925696594427, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI87082107, Length=394, Percent_Identity=86.8020304568528, Blast_Score=699, Evalue=0.0,
Organism=Escherichia coli, GI48994951, Length=378, Percent_Identity=35.978835978836, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1789163, Length=372, Percent_Identity=38.1720430107527, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1787493, Length=393, Percent_Identity=31.2977099236641, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1789386, Length=296, Percent_Identity=28.0405405405405, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17537053, Length=305, Percent_Identity=28.1967213114754, Blast_Score=115, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6321181, Length=374, Percent_Identity=33.9572192513369, Blast_Score=214, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24657991, Length=284, Percent_Identity=30.6338028169014, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: NA

Molecular weight: Translated: 40907; Mature: 40907

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFL
CCCHHHHHHHHHHHHCCHHHEEECCCCCHHHHCCCHHCCCCCHHHHCCHHHHHHHHHHHH
HQAGMTAPLARSLAMKGVAMTVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLD
HHCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHH
AAKAVALLVTNPDQTLSAMTERSTLRPRLPLIAVPTTAGTGSETTNVTVIIDAVSGRKQV
HHHEEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHHHH
LAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
HHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IGKSLPKAVGYGHDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCCCCC
MLLPTVMGFNRMVCRERFSQIGRALTNKKSDDRDAIAAVSELIAEVGQSKRLADAGAKPE
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCH
HYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQAELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFL
CCCHHHHHHHHHHHHCCHHHEEECCCCCHHHHCCCHHCCCCCHHHHCCHHHHHHHHHHHH
HQAGMTAPLARSLAMKGVAMTVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLD
HHCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHH
AAKAVALLVTNPDQTLSAMTERSTLRPRLPLIAVPTTAGTGSETTNVTVIIDAVSGRKQV
HHHEEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHHHH
LAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
HHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IGKSLPKAVGYGHDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCCCCC
MLLPTVMGFNRMVCRERFSQIGRALTNKKSDDRDAIAAVSELIAEVGQSKRLADAGAKPE
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCH
HYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7868611; 10464203; 11677609 [H]