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The map label for this gene is yqhD [H]

Identifier: 194736712

GI number: 194736712

Start: 3229517

End: 3230680

Strand: Direct

Name: yqhD [H]

Synonym: SeSA_A3348

Alternate gene names: 194736712

Gene position: 3229517-3230680 (Clockwise)

Preceding gene: 194735483

Following gene: 194736018

Centisome position: 68.58

GC content: 54.81

Gene sequence:

>1164_bases
ATGAACAATTTCACATTACATACCCCTACCCGCATTCTGTTTGGTAAAGGCGCTATCGTCGATCTCCGCGATCAGATCCC
GCAGGACTCCCGCGTGCTGATTACCTATGGCGGCGGTAGCGTGAAAAAGACCGGCGTACTGGCGCAAGTTCAGGAAGCGT
TAAAAGGACTGGATGTTCGGGAGTTTGGCGGTATTGAACCGAACCCGTCCTATGAAACGCTGATGAAGGCCGTGCAGCTT
GTGCGCGACGAAAATATTACCTTTCTGCTGGCCGTTGGCGGCGGTTCCGTACTGGACGGCACCAAATTTATCGCCGCAGC
GGCGCAATATACGGACGGCGTCGATCCGTGGCACATTCTGGAAACCGGCGGTACTGAGATTCGTAGCGCAATCCCGATGG
GGTCTGTGTTGACCCTACCGGCAACCGGCTCAGAATCGAACGCCGGCGCAGTCATTTCCCGTAAAACCACTGGCGACAAA
CAGGCCTTCCACTCCTCGTTCGTGCAACCGGTGTTTGCCGTACTGGACCCGGTCTACACCTATACATTGCCGCCGCGCCA
GGTTGCGAACGGCGTCGTGGATGCTTTCGTCCATACCGTTGAGCAGTACGTCACTTACCCGGTTAACGGCAAAATTCAGG
ATCGTTTCGCCGAAGGTATTTTACTCACACTGATCGAAGAAGGTCCCAAAGCGCTGCAAGAGCCTGAAAACTATGACGTC
CGCGCTAACGTGATGTGGGCCGCTACTCAGGCGTTGAATGGCCTGATTGGCGCTGGTGTTCCGCAGGACTGGGCGACGCA
TATGCTGGGCCATGAGCTTACCGCGATGCACGGTCTCGATCATGCCCAGACGCTGGCTATCATTCTGCCTGCGCTATGGA
ACGAAAAACGAGACGTTAAACGTGCAAAACTCCTGCAATATGCTGAACGTGTATGGAATATCACCGACGGTTCCGACGAC
GAGCGTATTGATGCCGCCATTGCCGCCACCCGCCGTTTCTTTGAACAGATGGGCGTGCCTACCCACTTGTCCGATTACGG
TCTGGATGGCAGCACTATTCCGGCGCTACTGGCTAAACTTGAGGCGCATGGATGCACAAATTTAGGTGAAAATCAGGATA
TTACGCTGGATGTCAGCCGTCGGATTTATGAAGCAGCGCGCTAA

Upstream 100 bases:

>100_bases
GCAGAAATGTGCATTGAGAGACATCCCTCACAAGACCACAATGATGACCATCAGGCAGACAGCCGCCTGCCCTCTTTTTA
CCCACATAAGGGAATGAGCA

Downstream 100 bases:

>100_bases
GGTTTTTTCGCCTCTGACTTTCGTTTTTGGCCATTTCGTCCAGACTTAAGTCACTTAGTCTCGCCGGCCCCGACTCCGGC
GAGCCAATTAAAAGAGGAAC

Product: alcohol dehydrogenase YqhD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNNFTLHTPTRILFGKGAIVDLRDQIPQDSRVLITYGGGSVKKTGVLAQVQEALKGLDVREFGGIEPNPSYETLMKAVQL
VRDENITFLLAVGGGSVLDGTKFIAAAAQYTDGVDPWHILETGGTEIRSAIPMGSVLTLPATGSESNAGAVISRKTTGDK
QAFHSSFVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTYPVNGKIQDRFAEGILLTLIEEGPKALQEPENYDV
RANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIILPALWNEKRDVKRAKLLQYAERVWNITDGSDD
ERIDAAIAATRRFFEQMGVPTHLSDYGLDGSTIPALLAKLEAHGCTNLGENQDITLDVSRRIYEAAR

Sequences:

>Translated_387_residues
MNNFTLHTPTRILFGKGAIVDLRDQIPQDSRVLITYGGGSVKKTGVLAQVQEALKGLDVREFGGIEPNPSYETLMKAVQL
VRDENITFLLAVGGGSVLDGTKFIAAAAQYTDGVDPWHILETGGTEIRSAIPMGSVLTLPATGSESNAGAVISRKTTGDK
QAFHSSFVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTYPVNGKIQDRFAEGILLTLIEEGPKALQEPENYDV
RANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIILPALWNEKRDVKRAKLLQYAERVWNITDGSDD
ERIDAAIAATRRFFEQMGVPTHLSDYGLDGSTIPALLAKLEAHGCTNLGENQDITLDVSRRIYEAAR
>Mature_387_residues
MNNFTLHTPTRILFGKGAIVDLRDQIPQDSRVLITYGGGSVKKTGVLAQVQEALKGLDVREFGGIEPNPSYETLMKAVQL
VRDENITFLLAVGGGSVLDGTKFIAAAAQYTDGVDPWHILETGGTEIRSAIPMGSVLTLPATGSESNAGAVISRKTTGDK
QAFHSSFVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTYPVNGKIQDRFAEGILLTLIEEGPKALQEPENYDV
RANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIILPALWNEKRDVKRAKLLQYAERVWNITDGSDD
ERIDAAIAATRRFFEQMGVPTHLSDYGLDGSTIPALLAKLEAHGCTNLGENQDITLDVSRRIYEAAR

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789386, Length=387, Percent_Identity=88.3720930232558, Blast_Score=711, Evalue=0.0,
Organism=Escherichia coli, GI48994951, Length=349, Percent_Identity=24.3553008595989, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1789163, Length=382, Percent_Identity=25.130890052356, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082107, Length=347, Percent_Identity=24.207492795389, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787493, Length=382, Percent_Identity=25.130890052356, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537053, Length=277, Percent_Identity=23.4657039711191, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321181, Length=359, Percent_Identity=25.3481894150418, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24657991, Length=346, Percent_Identity=24.2774566473988, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42075; Mature: 42075

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFTLHTPTRILFGKGAIVDLRDQIPQDSRVLITYGGGSVKKTGVLAQVQEALKGLDVR
CCCCEEECCCEEEECCCCEEEHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHH
EFGGIEPNPSYETLMKAVQLVRDENITFLLAVGGGSVLDGTKFIAAAAQYTDGVDPWHIL
HHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEE
ETGGTEIRSAIPMGSVLTLPATGSESNAGAVISRKTTGDKQAFHSSFVQPVFAVLDPVYT
ECCCHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCHHHE
YTLPPRQVANGVVDAFVHTVEQYVTYPVNGKIQDRFAEGILLTLIEEGPKALQEPENYDV
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHEEHHHHCHHHHCCCCCCCE
RANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIILPALWNEKRDVK
EEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHH
RAKLLQYAERVWNITDGSDDERIDAAIAATRRFFEQMGVPTHLSDYGLDGSTIPALLAKL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHH
EAHGCTNLGENQDITLDVSRRIYEAAR
HHCCCCCCCCCCCEEEEHHHHHHHHCC
>Mature Secondary Structure
MNNFTLHTPTRILFGKGAIVDLRDQIPQDSRVLITYGGGSVKKTGVLAQVQEALKGLDVR
CCCCEEECCCEEEECCCCEEEHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHH
EFGGIEPNPSYETLMKAVQLVRDENITFLLAVGGGSVLDGTKFIAAAAQYTDGVDPWHIL
HHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEE
ETGGTEIRSAIPMGSVLTLPATGSESNAGAVISRKTTGDKQAFHSSFVQPVFAVLDPVYT
ECCCHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCHHHE
YTLPPRQVANGVVDAFVHTVEQYVTYPVNGKIQDRFAEGILLTLIEEGPKALQEPENYDV
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHEEHHHHCHHHHCCCCCCCE
RANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIILPALWNEKRDVK
EEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHH
RAKLLQYAERVWNITDGSDDERIDAAIAATRRFFEQMGVPTHLSDYGLDGSTIPALLAKL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHH
EAHGCTNLGENQDITLDVSRRIYEAAR
HHCCCCCCCCCCCEEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]