Click here to switch to the map view.

The map label for this gene is nanE1 [H]

Identifier: 194736640

GI number: 194736640

Start: 1176949

End: 1177629

Strand: Reverse

Name: nanE1 [H]

Synonym: SeSA_A1194

Alternate gene names: 194736640

Gene position: 1177629-1176949 (Counterclockwise)

Preceding gene: 194736017

Following gene: 194738311

Centisome position: 25.01

GC content: 51.84

Gene sequence:

>681_bases
ATGTCACTATTAGCCAGGCTGGAACAAAGTGTACACGAAAACGGTGGGCTGATTGTCTCATGCCAACCGGTACCAGGCAG
CCCTATGGATAAACCTGAAATTGTGGCTGCAATGGCACAGGCAGCGGCTTCGGCGGGTGCGGTCGCTGTGCGCATTGAAG
GCATTGAGAATCTGCGGACTGTTCGTCCCCATCTTTCTGTTCCAATTATTGGGATAATTAAACGTGACCTTACAGGGTCG
CCAGTCCGTATCACTCCCTATTTACAGGATGTTGACGCCCTGGCGCAGGCAGGTGCCGATATTATCGCTTTTGATGCCTC
ATTCCGCTCTCGCCCGGTTGATATTGATAGTTTACTGACACGTATTCGCCTGCATGGATTACTGGCGATGGCAGACTGTT
CAACCGTGAATGAAGGCATAAGTTGCCATCAGAAAGGAATCGAATTCATTGGTACAACATTGTCTGGCTATACCGGCCCC
ATCACGCCGGTTGAGCCAGATTTGGCAATGGTGACGCAACTGAGCCATGCAGGTTGTCGTGTTATTGCCGAGGGGCGCTA
TAACACGCCTGCACTGGCGGCCAATGCTATTGAGCATGGTGCCTGGGCAGTTACCGTTGGTTCCGCTATCACCCGTATCG
AGCATATCTGTCAGTGGTTCAGTCACGCAGTAAAACGCTGA

Upstream 100 bases:

>100_bases
GACTGTGTTCACATTTTTCTATCTTTTTGCTTGATGCAGCAACACTCCACAACATAATATAAAACGGAGCAAAACTTCAA
AATATATAAGGCGGAACTGG

Downstream 100 bases:

>100_bases
ACAGGAAAAGAAAATGAACACGCTTACTATTGATATTTATGTCTCAGAGAATAATCCGACGTTAATAATGCTATCGGCAA
ATACGATACCCAGGCCTGAA

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase 1 [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MSLLARLEQSVHENGGLIVSCQPVPGSPMDKPEIVAAMAQAAASAGAVAVRIEGIENLRTVRPHLSVPIIGIIKRDLTGS
PVRITPYLQDVDALAQAGADIIAFDASFRSRPVDIDSLLTRIRLHGLLAMADCSTVNEGISCHQKGIEFIGTTLSGYTGP
ITPVEPDLAMVTQLSHAGCRVIAEGRYNTPALAANAIEHGAWAVTVGSAITRIEHICQWFSHAVKR

Sequences:

>Translated_226_residues
MSLLARLEQSVHENGGLIVSCQPVPGSPMDKPEIVAAMAQAAASAGAVAVRIEGIENLRTVRPHLSVPIIGIIKRDLTGS
PVRITPYLQDVDALAQAGADIIAFDASFRSRPVDIDSLLTRIRLHGLLAMADCSTVNEGISCHQKGIEFIGTTLSGYTGP
ITPVEPDLAMVTQLSHAGCRVIAEGRYNTPALAANAIEHGAWAVTVGSAITRIEHICQWFSHAVKR
>Mature_225_residues
SLLARLEQSVHENGGLIVSCQPVPGSPMDKPEIVAAMAQAAASAGAVAVRIEGIENLRTVRPHLSVPIIGIIKRDLTGSP
VRITPYLQDVDALAQAGADIIAFDASFRSRPVDIDSLLTRIRLHGLLAMADCSTVNEGISCHQKGIEFIGTTLSGYTGPI
TPVEPDLAMVTQLSHAGCRVIAEGRYNTPALAANAIEHGAWAVTVGSAITRIEHICQWFSHAVKR

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential) [H]

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family [H]

Homologues:

Organism=Escherichia coli, GI1789617, Length=226, Percent_Identity=70.7964601769911, Blast_Score=317, Evalue=3e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060 [H]

Pfam domain/function: PF04131 NanE [H]

EC number: =5.1.3.9 [H]

Molecular weight: Translated: 23973; Mature: 23842

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLARLEQSVHENGGLIVSCQPVPGSPMDKPEIVAAMAQAAASAGAVAVRIEGIENLRT
CHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHH
VRPHLSVPIIGIIKRDLTGSPVRITPYLQDVDALAQAGADIIAFDASFRSRPVDIDSLLT
HCCCCCCCCCEEEECCCCCCCEEEEHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHH
RIRLHGLLAMADCSTVNEGISCHQKGIEFIGTTLSGYTGPITPVEPDLAMVTQLSHAGCR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCE
VIAEGRYNTPALAANAIEHGAWAVTVGSAITRIEHICQWFSHAVKR
EEECCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLLARLEQSVHENGGLIVSCQPVPGSPMDKPEIVAAMAQAAASAGAVAVRIEGIENLRT
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHH
VRPHLSVPIIGIIKRDLTGSPVRITPYLQDVDALAQAGADIIAFDASFRSRPVDIDSLLT
HCCCCCCCCCEEEECCCCCCCEEEEHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHH
RIRLHGLLAMADCSTVNEGISCHQKGIEFIGTTLSGYTGPITPVEPDLAMVTQLSHAGCR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCE
VIAEGRYNTPALAANAIEHGAWAVTVGSAITRIEHICQWFSHAVKR
EEECCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA