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The map label for this gene is tusC

Identifier: 194736554

GI number: 194736554

Start: 3501043

End: 3501399

Strand: Reverse

Name: tusC

Synonym: SeSA_A3646

Alternate gene names: 194736554

Gene position: 3501399-3501043 (Counterclockwise)

Preceding gene: 194735809

Following gene: 194737029

Centisome position: 74.35

GC content: 53.5

Gene sequence:

>357_bases
ATGAAACGTATTGCATTTGTCTTTTCCACCGCGCCGCACGGCAGCGCCTCAGGCCGTGAAGGACTGGATGCGCTGCTGGC
GACGTCAGCTCTAACGGAAGCGCTGGGCGTCTTTTTTATCAGCGACGGCGTCTTTCAGTTATTACCGGGACAAAAACCAG
ACGCTGTGCTGGCGCGTGATTATATTGCTACTTTCAAGCTCTTTGATTTGTACGATATTGATCAATGCTGGATCTGCGCG
GCATCGCTGCGCGAGCGTGGTCTGGAGAACGTTAATTTTGTGGTAGACGCCACGCCGCTGGAACCCGTAGCGTTACGCCG
CGAGCTTGGCAACTATGATGTCATCCTGAGATTCTGA

Upstream 100 bases:

>100_bases
TGGCGTTGCCGTCCGCCAATCTTCAGCCGGGCTTTACGCTAAGCGGACTGGGCGCGCTGGCGGAGGCATCTCTCACCTGC
GATCGGGTGGTGCAGTTTTA

Downstream 100 bases:

>100_bases
GGCGTTTATGCTGCATACCTTACCTCATTGCGCCTCGGGCGTTGATTTTCCCGCTTTGCTGCGCCTGCTAAAAGAGGGCG
ATGCGCTTTTGCTGCTCCAG

Product: sulfur relay protein TusC

Products: NA

Alternate protein names: tRNA 2-thiouridine synthesizing protein C

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MKRIAFVFSTAPHGSASGREGLDALLATSALTEALGVFFISDGVFQLLPGQKPDAVLARDYIATFKLFDLYDIDQCWICA
ASLRERGLENVNFVVDATPLEPVALRRELGNYDVILRF

Sequences:

>Translated_118_residues
MKRIAFVFSTAPHGSASGREGLDALLATSALTEALGVFFISDGVFQLLPGQKPDAVLARDYIATFKLFDLYDIDQCWICA
ASLRERGLENVNFVVDATPLEPVALRRELGNYDVILRF
>Mature_118_residues
MKRIAFVFSTAPHGSASGREGLDALLATSALTEALGVFFISDGVFQLLPGQKPDAVLARDYIATFKLFDLYDIDQCWICA
ASLRERGLENVNFVVDATPLEPVALRRELGNYDVILRF

Specific function: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions

COG id: COG2923

COG function: function code P; Uncharacterized protein involved in the oxidation of intracellular sulfur

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dsrF/tusC family

Homologues:

Organism=Escherichia coli, GI1789742, Length=119, Percent_Identity=84.0336134453782, Blast_Score=200, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TUSC_SALA4 (B5F8G2)

Other databases:

- EMBL:   CP001138
- RefSeq:   YP_002148369.1
- ProteinModelPortal:   B5F8G2
- SMR:   B5F8G2
- GeneID:   6796724
- GenomeReviews:   CP001138_GR
- KEGG:   sea:SeAg_B3647
- HOGENOM:   HBG496129
- OMA:   FKVLPLY
- ProtClustDB:   PRK00211
- GO:   GO:0005737
- HAMAP:   MF_00389
- InterPro:   IPR003787
- InterPro:   IPR017462
- TIGRFAMs:   TIGR03010

Pfam domain/function: PF02635 DrsE

EC number: NA

Molecular weight: Translated: 13011; Mature: 13011

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIAFVFSTAPHGSASGREGLDALLATSALTEALGVFFISDGVFQLLPGQKPDAVLARD
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCHHHHHH
YIATFKLFDLYDIDQCWICAASLRERGLENVNFVVDATPLEPVALRRELGNYDVILRF
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCEEEEEEC
>Mature Secondary Structure
MKRIAFVFSTAPHGSASGREGLDALLATSALTEALGVFFISDGVFQLLPGQKPDAVLARD
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCHHHHHH
YIATFKLFDLYDIDQCWICAASLRERGLENVNFVVDATPLEPVALRRELGNYDVILRF
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA