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The map label for this gene is sstT [H]

Identifier: 194736527

GI number: 194736527

Start: 3301024

End: 3302268

Strand: Direct

Name: sstT [H]

Synonym: SeSA_A3416

Alternate gene names: 194736527

Gene position: 3301024-3302268 (Clockwise)

Preceding gene: 194737550

Following gene: 194735796

Centisome position: 70.1

GC content: 55.5

Gene sequence:

>1245_bases
ATGGCTACGCAACGAGCATCAGGGCTACTGCAGCGTTTAGCGCAAGGCAGTCTGGTTAAACAAATTTTAGTGGGTCTGGT
ACTGGGGATTTTACTGGCATGGATTTCTAAGCCTGCGGCAGAAGCGGTTGGCTTGCTTGGCACCCTGTTCGTCGGCGCCT
TAAAAGCGGTCGCCCCCGTTCTGGTGCTGATGCTGGTCATGGCCTCGATCGCCAACCACCAGCACGGTCAAAAAACCAAT
ATTCGCCCTATTCTCTTTCTTTACCTGCTAGGCACCTTTTCAGCCGCGCTGGCGGCCGTTGTGTTCAGCTTCGCCTTCCC
TTCAACGCTGCATCTGTCCAGTAGCGCCCAAGATATCGTGCCGCCGTCCGGCATTGTAGAAGTTCTGCGCGGTCTGCTGA
TGAGTATGGTGTCGAACCCCATCGACGCGCTGCTGAACGCTAACTATATCGGGATTCTGGTATGGGCCGTCAGTCTGGGA
TTTGCCCTGCGTCATGGCAATGAAACTACCAAAAACCTCGTGAACGATATGTCTAACGCCGTGACCTTTATGGTGAAACT
GGTGATCCGTTTCGCGCCAATCGGTATTTTTGGTCTGGTTTCATCAACGCTTGCAACCACCGGCTTCTCCACCCTGTGGG
GCTATGCGCACCTGCTGGTCGTCTTGATTGGCTGTATGCTGCTGGTCGCGCTGGTGGTCAACCCGCTGTTGGTATTCTGG
AAAATTCGTCGCAACCCTTATCCGCTGGTGTTCGCCTGCCTGCGTGAAAGCGGCGTTTATGCCTTCTTTACCCGCAGCTC
TGCCGCCAATATTCCAGTGAATATGGCGCTGTGCGAAAAGCTGAATCTGGACAGGGATACTTACTCCGTTTCCATTCCGC
TGGGCGCCACCATCAATATGGCCGGCGCGGCAATTACCATTACGGTTCTGACGTTGGCGGCAGTTCATACGTTAGGCGTC
CCGGTGGATCTGCCTACAGCGCTGCTGCTGAGCGTGGTGGCCTCGCTGTGTGCTTGCGGCGCCTCCGGCGTGGCAGGCGG
TTCATTGCTGCTAATCCCGCTGGCGTGCAACATGTTTGGCATCCCGAACGATATCGCGATGCAGGTAGTAGCGGTCGGCT
TTATTATCGGCGTATTGCAGGATTCGTGTGAAACGGCGCTGAACTCATCTACCGATGTTCTGTTCACTGCGGCAGCCTGC
CAGGCAGAGGACGAACGTCTGGCGAATAACGCCTTGCGTAGCTAA

Upstream 100 bases:

>100_bases
TTTCCTTATACTCAACCAGGCAAACACTTTGTTACATCCTGAAAGATGCGCCGTAAGAGCGTGCAGGGGATGACCAGCAA
CACAATACAAGGAACATGAA

Downstream 100 bases:

>100_bases
GTGATTATCGATGCCGGATGGCGCGTGCCATCCGGCGTGATGATAGATCTGAATCTCCCAATCCATAGGCTGTGACGGAA
AGCGAATTGATGTTCACGCG

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MATQRASGLLQRLAQGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPVLVLMLVMASIANHQHGQKTN
IRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAQDIVPPSGIVEVLRGLLMSMVSNPIDALLNANYIGILVWAVSLG
FALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAHLLVVLIGCMLLVALVVNPLLVFW
KIRRNPYPLVFACLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGV
PVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGIPNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAAC
QAEDERLANNALRS

Sequences:

>Translated_414_residues
MATQRASGLLQRLAQGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPVLVLMLVMASIANHQHGQKTN
IRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAQDIVPPSGIVEVLRGLLMSMVSNPIDALLNANYIGILVWAVSLG
FALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAHLLVVLIGCMLLVALVVNPLLVFW
KIRRNPYPLVFACLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGV
PVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGIPNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAAC
QAEDERLANNALRS
>Mature_413_residues
ATQRASGLLQRLAQGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPVLVLMLVMASIANHQHGQKTNI
RPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAQDIVPPSGIVEVLRGLLMSMVSNPIDALLNANYIGILVWAVSLGF
ALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAHLLVVLIGCMLLVALVVNPLLVFWK
IRRNPYPLVFACLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGVP
VDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGIPNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAACQ
AEDERLANNALRS

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI4827012, Length=240, Percent_Identity=25.4166666666667, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI169790839, Length=251, Percent_Identity=23.5059760956175, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI223468564, Length=254, Percent_Identity=27.9527559055118, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI223468566, Length=254, Percent_Identity=27.9527559055118, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI5032093, Length=254, Percent_Identity=27.9527559055118, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI21314632, Length=256, Percent_Identity=27.34375, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI66773030, Length=275, Percent_Identity=24, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI194239697, Length=307, Percent_Identity=23.7785016286645, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1789473, Length=414, Percent_Identity=93.4782608695652, Blast_Score=749, Evalue=0.0,
Organism=Escherichia coli, GI1789947, Length=359, Percent_Identity=24.7910863509749, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1790514, Length=429, Percent_Identity=23.3100233100233, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537407, Length=434, Percent_Identity=24.6543778801843, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71996953, Length=276, Percent_Identity=27.1739130434783, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71983099, Length=275, Percent_Identity=26.1818181818182, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71983106, Length=275, Percent_Identity=26.1818181818182, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193206505, Length=261, Percent_Identity=28.3524904214559, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24583025, Length=260, Percent_Identity=25.3846153846154, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17137668, Length=260, Percent_Identity=25.3846153846154, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24583023, Length=260, Percent_Identity=25.3846153846154, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 43457; Mature: 43326

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00435 PEROXIDASE_1 ; PS00713 NA_DICARBOXYL_SYMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQRASGLLQRLAQGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAQDIV
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCC
PPSGIVEVLRGLLMSMVSNPIDALLNANYIGILVWAVSLGFALRHGNETTKNLVNDMSNA
CCHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAHLLVVLIGCMLLVALVVNPLLVFW
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIRRNPYPLVFACLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINM
HHCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCEEEC
AGAAITITVLTLAAVHTLGVPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFG
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHCC
IPNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAACQAEDERLANNALRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure 
ATQRASGLLQRLAQGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAQDIV
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCC
PPSGIVEVLRGLLMSMVSNPIDALLNANYIGILVWAVSLGFALRHGNETTKNLVNDMSNA
CCHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAHLLVVLIGCMLLVALVVNPLLVFW
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIRRNPYPLVFACLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINM
HHCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCEEEC
AGAAITITVLTLAAVHTLGVPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFG
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHCC
IPNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAACQAEDERLANNALRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]