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The map label for this gene is dmsC1 [H]

Identifier: 194736452

GI number: 194736452

Start: 1056906

End: 1057769

Strand: Direct

Name: dmsC1 [H]

Synonym: SeSA_A1080

Alternate gene names: 194736452

Gene position: 1056906-1057769 (Clockwise)

Preceding gene: 194737930

Following gene: 194736955

Centisome position: 22.44

GC content: 58.1

Gene sequence:

>864_bases
ATGGGAAGTGGATGGCATGAATGGCCGTTGATGATCTTCACGGTCTTTGGTCAGTGCGTGGCCGGTGGTTTTATTGTTCT
GGCTCTGGCGCTGATGAAGGGCGACCTGCGCGCGGAAACGCAGCAGCGGGTGATCGCCTGTATGTTTGGTCTGTGGGTGC
TGATGGGGATTGGCTTTATCGCCTCGATGCTGCATCTGGGCTCGCCGATGCGCGCGTTTAACTCGCTTAACCGCGTAGGT
GCTTCCGCACTGAGCAATGAAATTGCCAGCGGCTCGGTGTTTTTTGCGGTCGGCGGGATTGGCTGGCTGCTGGCGGTACT
GAAAAAGCTGCCGCCGGCACTGCGCACACTCTGGCTGATTATCACGATGGTACTGGGCGTCGTCTTCGTCTGGATGATGG
TACGCGTCTATAACAGCATCGATACAGTACCGACCTGGTATAGCGTCTGGACGCCGCTGGGCTTCTTCCTGACGCTCTTT
ATGGGGGGGCCGCTACTGGGTTATCTGCTGCTGCGCATCGCGGGCGTGAACGGTTGGGCGATGCGTTTGTTACCTGCGGT
GTCGGTGCTGGCGCTGGTGGTTATTGCCATTATGGTGGCCATGCAGGGCGCGGAACTGGCGACGATTCACAGTTCCATTC
AGCAGGCGTCTGCTCTGGTACCGGATTATGGTTCGCTGATGGCCTGGCGTATGGTGCTGCTTGCGGCGGCGTTGTGCTGC
TGGATTGTGCCACAGTTAAAAGGGTATCAACCTGCGGTACCGTTGCTCTCTGTCGCCTTCATTCTGATGCTGGCGGGGGA
ATTGATTGGCCGCGGCGTATTCTATGGGCTGCATATGACCGTGGGCATGGCGGTAGCCAGCTAA

Upstream 100 bases:

>100_bases
GCGCATTTCACGAAGCCGAATATTGTGATTAAACCCAACGCCAACAGCCGCCCGACCGGGGACATCACCGGTTATCTGGC
CAATCCGAAGGAGGTATAAG

Downstream 100 bases:

>100_bases
CGCGTTGACGCGTATTCGGCCTGCAGAACGTGCAGGCCGAATACGCCTTTAGCCGCCATCAATTTAAGGGATATAACCGG
GGCGGAGAAGGTGCATATAA

Product: anaerobic dimethyl sulfoxide reductase, C subunit

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase anchor subunit [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MGSGWHEWPLMIFTVFGQCVAGGFIVLALALMKGDLRAETQQRVIACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVG
ASALSNEIASGSVFFAVGGIGWLLAVLKKLPPALRTLWLIITMVLGVVFVWMMVRVYNSIDTVPTWYSVWTPLGFFLTLF
MGGPLLGYLLLRIAGVNGWAMRLLPAVSVLALVVIAIMVAMQGAELATIHSSIQQASALVPDYGSLMAWRMVLLAAALCC
WIVPQLKGYQPAVPLLSVAFILMLAGELIGRGVFYGLHMTVGMAVAS

Sequences:

>Translated_287_residues
MGSGWHEWPLMIFTVFGQCVAGGFIVLALALMKGDLRAETQQRVIACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVG
ASALSNEIASGSVFFAVGGIGWLLAVLKKLPPALRTLWLIITMVLGVVFVWMMVRVYNSIDTVPTWYSVWTPLGFFLTLF
MGGPLLGYLLLRIAGVNGWAMRLLPAVSVLALVVIAIMVAMQGAELATIHSSIQQASALVPDYGSLMAWRMVLLAAALCC
WIVPQLKGYQPAVPLLSVAFILMLAGELIGRGVFYGLHMTVGMAVAS
>Mature_286_residues
GSGWHEWPLMIFTVFGQCVAGGFIVLALALMKGDLRAETQQRVIACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVGA
SALSNEIASGSVFFAVGGIGWLLAVLKKLPPALRTLWLIITMVLGVVFVWMMVRVYNSIDTVPTWYSVWTPLGFFLTLFM
GGPLLGYLLLRIAGVNGWAMRLLPAVSVLALVVIAIMVAMQGAELATIHSSIQQASALVPDYGSLMAWRMVLLAAALCCW
IVPQLKGYQPAVPLLSVAFILMLAGELIGRGVFYGLHMTVGMAVAS

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. DmsC anchors the dmsAB dimer to the membrane and stabilizes it [H]

COG id: COG3302

COG function: function code R; DMSO reductase anchor subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli ynfH [H]

Homologues:

Organism=Escherichia coli, GI1787123, Length=287, Percent_Identity=89.5470383275261, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1787873, Length=286, Percent_Identity=58.041958041958, Blast_Score=300, Evalue=8e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007059 [H]

Pfam domain/function: PF04976 DmsC [H]

EC number: NA

Molecular weight: Translated: 30953; Mature: 30822

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GSGWHEWPLMIFTVFGQCVAGGFIVLALALMKGDLRAETQQRVIACMFGLWVLMGIGFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASMLHLGSPMRAFNSLNRVGASALSNEIASGSVFFAVGGIGWLLAVLKKLPPALRTLWLI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ITMVLGVVFVWMMVRVYNSIDTVPTWYSVWTPLGFFLTLFMGGPLLGYLLLRIAGVNGWA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHH
MRLLPAVSVLALVVIAIMVAMQGAELATIHSSIQQASALVPDYGSLMAWRMVLLAAALCC
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
WIVPQLKGYQPAVPLLSVAFILMLAGELIGRGVFYGLHMTVGMAVAS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 8429002; 2170332 [H]