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The map label for this gene is dmsC [H]

Identifier: 194736181

GI number: 194736181

Start: 4445540

End: 4446313

Strand: Direct

Name: dmsC [H]

Synonym: SeSA_A4562

Alternate gene names: 194736181

Gene position: 4445540-4446313 (Clockwise)

Preceding gene: 194736806

Following gene: 194734044

Centisome position: 94.4

GC content: 60.85

Gene sequence:

>774_bases
ATGCATGAGTTACCGCTGGTCTTTTTTACGGTCTTTACCCAGAGCGCGGTCGGCGCGTTTATTCTGCTGCTGATTGGCGG
CGCAATGGGGCTGGTCGCGCCGCGGCGTAAGGCTATCGGTCTGTTCTCGGTGATGTGCCTGTTTGGGCTTGGCGTCATTG
TCGGCATCTTCCACGTCGGGCAACCGCTGCGCGCGCTGAATATGCTGCTGCGCGTCGGACATTCGCCGATGAGTAACGAG
ATTGTCTTGTCGGCGGCTTTTGCGGCGCTCGGCGGTCTGGGGGCGCTCGGTTTGTTGCTGAACCGGGCGACGCCGCTGTG
TAACGCGTTGGTATGGTTGGCAGCGATAGTCGGGGTGGTCTTCTTATACGCCGTTCCGCAGATTTACCAACTGCCGACGG
TGGCGACCTGGCGTTCATCTTACACCACGGCAATGATGATATTGACGCCGTTGATTGGCGGCGGCGCGTTGGCGGCATTG
TTTGGCGTGCGCCGTCTGGGGCTACTGGTCAGCGTGTTGGCGATTTTGGTGAGCTTTTGTCTGCGCCCGGGCTATATGGC
GACGCTGATGAGCGCCGATAGCGCTTTGACCGCTGCGCAGCATAGCTGGTTTACCGCCCAGGCGATATTGCTGGCGGTGG
GCGTGGTCGGGGTGGTGGCCTGCGCGCGCCTGAAATCGAGCGCTGCGGTGCTGGCCATGACGGCAGTGGTGGTTATCGCG
GCGGAGTTGGCGGGTAGGATTGCGTTTTACAATCTGTGGACGCTGCCAATGTAG

Upstream 100 bases:

>100_bases
GCGTCGTTCACCCATCCTAACCTCATTATTAAACCGCATCCGAAAGCGAGACCCACAGGCGATACGGAAGGCGCAATCAT
GAACATTCGGGAGGTGCGCC

Downstream 100 bases:

>100_bases
TTTTTTGCCCGGTTTATGCCATGTAAGCCTGATAAGCGTAGCGTCATCAGGCGAAATATTTCAGGAGCTATTGCTATGCC
TTCCCGTGCTGTTTTGCCGC

Product: dmso reductase anchor subunit

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase anchor subunit [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MHELPLVFFTVFTQSAVGAFILLLIGGAMGLVAPRRKAIGLFSVMCLFGLGVIVGIFHVGQPLRALNMLLRVGHSPMSNE
IVLSAAFAALGGLGALGLLLNRATPLCNALVWLAAIVGVVFLYAVPQIYQLPTVATWRSSYTTAMMILTPLIGGGALAAL
FGVRRLGLLVSVLAILVSFCLRPGYMATLMSADSALTAAQHSWFTAQAILLAVGVVGVVACARLKSSAAVLAMTAVVVIA
AELAGRIAFYNLWTLPM

Sequences:

>Translated_257_residues
MHELPLVFFTVFTQSAVGAFILLLIGGAMGLVAPRRKAIGLFSVMCLFGLGVIVGIFHVGQPLRALNMLLRVGHSPMSNE
IVLSAAFAALGGLGALGLLLNRATPLCNALVWLAAIVGVVFLYAVPQIYQLPTVATWRSSYTTAMMILTPLIGGGALAAL
FGVRRLGLLVSVLAILVSFCLRPGYMATLMSADSALTAAQHSWFTAQAILLAVGVVGVVACARLKSSAAVLAMTAVVVIA
AELAGRIAFYNLWTLPM
>Mature_257_residues
MHELPLVFFTVFTQSAVGAFILLLIGGAMGLVAPRRKAIGLFSVMCLFGLGVIVGIFHVGQPLRALNMLLRVGHSPMSNE
IVLSAAFAALGGLGALGLLLNRATPLCNALVWLAAIVGVVFLYAVPQIYQLPTVATWRSSYTTAMMILTPLIGGGALAAL
FGVRRLGLLVSVLAILVSFCLRPGYMATLMSADSALTAAQHSWFTAQAILLAVGVVGVVACARLKSSAAVLAMTAVVVIA
AELAGRIAFYNLWTLPM

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. DmsC anchors the dmsAB dimer to the membrane and stabilizes it [H]

COG id: COG3302

COG function: function code R; DMSO reductase anchor subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787123, Length=273, Percent_Identity=34.0659340659341, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1787873, Length=157, Percent_Identity=40.1273885350318, Blast_Score=97, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007059 [H]

Pfam domain/function: PF04976 DmsC [H]

EC number: NA

Molecular weight: Translated: 26868; Mature: 26868

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHEECCCC
>Mature Secondary Structure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HHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8635740 [H]