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The map label for this gene is rhtC [H]

Identifier: 194736153

GI number: 194736153

Start: 4641143

End: 4641784

Strand: Reverse

Name: rhtC [H]

Synonym: SeSA_A4781

Alternate gene names: 194736153

Gene position: 4641784-4641143 (Counterclockwise)

Preceding gene: 194734218

Following gene: 194735536

Centisome position: 98.57

GC content: 55.76

Gene sequence:

>642_bases
ATGGAACAGGTTACAACGTTATTTCCTCCGGCGTTTCCCGCACTGGCGCTGGCGCATTTTATGGCGCTGCTCAGCCCGGG
TCCGGACTTCTTTTTGCTGGTCGGTTACGCCGTACGCTATCGGCTGCGCGGTAGCGTCGGGCTGTGCCTCGGCATTGCGG
CGGGAAATGGGCTCTATATTCTGCTGGTGGTGATTGGGTCAGGGCTACTACGTCAGACGCCGCTGCTCTTTACCATCATC
GAACTATTAGGTGCCGCCTACCTGCTATGGGTGGGCCGTCAACTGTTGAAAAGCCGCGCCGGGCCGCTGGAGTGGCGGTA
CGCCGCATCGGCATGTCCGTCACTGGCAAAACAACTATTACTGGGGCTAGGTTCATCGCTGTTGAATCCGAAAAATGCTC
TGTTTTATCTGGCGCTAATGACCGCCCTGCTGGGCCCAAACGTGACCGTTACACAGCAGGCCATATGTGGAATCTGGATG
ACCAGCGTAGTGTTACTCTGGGATCTGCTGCTGATAACGCTTATCGCCCTGCCGCAAATTCAAGGTCGTCTGGGTAATCT
TGTCTGGAAAATTGAACGCGCCGCCGGCGGCATTCTGATCGCCTTTGGCTGCTGGATTGTGTGGCAGTTCATTACAAGTT
AA

Upstream 100 bases:

>100_bases
CGGCAACGCCGCGTCAGTACGCGCAGAACAGATCAATATCCGACAATAAATAGCGCATCCGCAGGTATAGGCTGACCTCA
GTATCATCACTGAGGTTACT

Downstream 100 bases:

>100_bases
ATCAATGAGGGGCAGCTTTATACGGTGGTCAACGTTGCCCGGGCAGATGAATAGGGTCTGCATCATTCGAACCCTTTCCT
TCTTATAATGCCGACGCCGC

Product: transporter LysE family protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MEQVTTLFPPAFPALALAHFMALLSPGPDFFLLVGYAVRYRLRGSVGLCLGIAAGNGLYILLVVIGSGLLRQTPLLFTII
ELLGAAYLLWVGRQLLKSRAGPLEWRYAASACPSLAKQLLLGLGSSLLNPKNALFYLALMTALLGPNVTVTQQAICGIWM
TSVVLLWDLLLITLIALPQIQGRLGNLVWKIERAAGGILIAFGCWIVWQFITS

Sequences:

>Translated_213_residues
MEQVTTLFPPAFPALALAHFMALLSPGPDFFLLVGYAVRYRLRGSVGLCLGIAAGNGLYILLVVIGSGLLRQTPLLFTII
ELLGAAYLLWVGRQLLKSRAGPLEWRYAASACPSLAKQLLLGLGSSLLNPKNALFYLALMTALLGPNVTVTQQAICGIWM
TSVVLLWDLLLITLIALPQIQGRLGNLVWKIERAAGGILIAFGCWIVWQFITS
>Mature_213_residues
MEQVTTLFPPAFPALALAHFMALLSPGPDFFLLVGYAVRYRLRGSVGLCLGIAAGNGLYILLVVIGSGLLRQTPLLFTII
ELLGAAYLLWVGRQLLKSRAGPLEWRYAASACPSLAKQLLLGLGSSLLNPKNALFYLALMTALLGPNVTVTQQAICGIWM
TSVVLLWDLLLITLIALPQIQGRLGNLVWKIERAAGGILIAFGCWIVWQFITS

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=204, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23063; Mature: 23063

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQVTTLFPPAFPALALAHFMALLSPGPDFFLLVGYAVRYRLRGSVGLCLGIAAGNGLYI
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCEE
LLVVIGSGLLRQTPLLFTIIELLGAAYLLWVGRQLLKSRAGPLEWRYAASACPSLAKQLL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LGLGSSLLNPKNALFYLALMTALLGPNVTVTQQAICGIWMTSVVLLWDLLLITLIALPQI
HHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGRLGNLVWKIERAAGGILIAFGCWIVWQFITS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MEQVTTLFPPAFPALALAHFMALLSPGPDFFLLVGYAVRYRLRGSVGLCLGIAAGNGLYI
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCEE
LLVVIGSGLLRQTPLLFTIIELLGAAYLLWVGRQLLKSRAGPLEWRYAASACPSLAKQLL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LGLGSSLLNPKNALFYLALMTALLGPNVTVTQQAICGIWMTSVVLLWDLLLITLIALPQI
HHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGRLGNLVWKIERAAGGILIAFGCWIVWQFITS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]