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The map label for this gene is uxuR [H]

Identifier: 194735969

GI number: 194735969

Start: 4624153

End: 4624926

Strand: Direct

Name: uxuR [H]

Synonym: SeSA_A4761

Alternate gene names: 194735969

Gene position: 4624153-4624926 (Clockwise)

Preceding gene: 194735515

Following gene: 194737211

Centisome position: 98.2

GC content: 54.52

Gene sequence:

>774_bases
ATGAAATCAAACACTTCTCAGCAAAGACCTTACCAGGAAGTGGGCGCAATGATACGGGATCTGATTGTTCAGACGCCGTA
CCGCCCCGGGGAGCGCTTGCCGCCGGAAAGAGAGATCGCTGAGAGGCTCAATGTGACGCGTACCGTCGTGCGTGAAGCGC
TGATCATGCTGGAAATTAAAGGTCTGGTTGAAGTCCGCCGCGGCGCCGGGATCTACGTGCTCGACAGCGCGGATAATAAC
GAGATGGAAGGCGCTGACGTCAATCACTGTAATGATGCCGGGCCGTTTGAACTGTTACAGGCGCGTCAGTTGCTGGAAAG
CAATATCGCTGAATTTGCCGCTCTGCAGGCCACCCGCGAAGACATCATTAAAATGCGCCAGGCGTTACAACTGGAAGAGC
GAGAGCTCGCCTCCAGCGCGCCGGGCGGCTCAGAAAGCGGCGATATGCAGTTTCATCTGGCCATTGCCGAAGCGACCCAT
AACAGTATGTTGGTAGAGCTCTTCCGTCAGTCCTGGCAATGGCGTGAAAATAATCCGATGTGGCTCCAGCTTCATAGCCA
TCTGGGCGATACGCTTTACCGTAAGGAGTGGCTGGTCGATCATAAGCAGATCCTCGCGGCGTTAATTAAGAAAGACGCCC
GCGCAGCGAAGCTGGCGATGTGGCAGCACCTGGAAAACGTGAAGCAGCGTCTGCTGGAGTTTTCCAATGTTGATGACATC
TACTTTGATGGCTATCTGTTTGAGTCATGGCCGCTGGACAACGTTGATGCCTGA

Upstream 100 bases:

>100_bases
GTTGACCAGTTTCGCGTTTTTGGTGTGCTACGCGTGCTATCTCTCTTTACAAATGCTATAGTCTGATACCGGGAAATCGC
ATCGGACGGGCACGACCAAT

Downstream 100 bases:

>100_bases
TTATACCTGGAATAGCGTGGGCAGACCCAGTCCACGTTTTACTTCCTGTAGCGTCTTTTGAGTGACCTCATGCGCCCGCT
CGCTACCTTTTTTCAGCAAT

Product: DNA-binding transcriptional repressor UxuR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKSNTSQQRPYQEVGAMIRDLIVQTPYRPGERLPPEREIAERLNVTRTVVREALIMLEIKGLVEVRRGAGIYVLDSADNN
EMEGADVNHCNDAGPFELLQARQLLESNIAEFAALQATREDIIKMRQALQLEERELASSAPGGSESGDMQFHLAIAEATH
NSMLVELFRQSWQWRENNPMWLQLHSHLGDTLYRKEWLVDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
YFDGYLFESWPLDNVDA

Sequences:

>Translated_257_residues
MKSNTSQQRPYQEVGAMIRDLIVQTPYRPGERLPPEREIAERLNVTRTVVREALIMLEIKGLVEVRRGAGIYVLDSADNN
EMEGADVNHCNDAGPFELLQARQLLESNIAEFAALQATREDIIKMRQALQLEERELASSAPGGSESGDMQFHLAIAEATH
NSMLVELFRQSWQWRENNPMWLQLHSHLGDTLYRKEWLVDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
YFDGYLFESWPLDNVDA
>Mature_257_residues
MKSNTSQQRPYQEVGAMIRDLIVQTPYRPGERLPPEREIAERLNVTRTVVREALIMLEIKGLVEVRRGAGIYVLDSADNN
EMEGADVNHCNDAGPFELLQARQLLESNIAEFAALQATREDIIKMRQALQLEERELASSAPGGSESGDMQFHLAIAEATH
NSMLVELFRQSWQWRENNPMWLQLHSHLGDTLYRKEWLVDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
YFDGYLFESWPLDNVDA

Specific function: Repressor for the uxuRBA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=257, Percent_Identity=89.4941634241245, Blast_Score=477, Evalue=1e-136,
Organism=Escherichia coli, GI87082208, Length=262, Percent_Identity=47.7099236641221, Blast_Score=210, Evalue=7e-56,
Organism=Escherichia coli, GI1790032, Length=232, Percent_Identity=29.3103448275862, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786303, Length=229, Percent_Identity=31.8777292576419, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789353, Length=249, Percent_Identity=28.1124497991968, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI48994955, Length=238, Percent_Identity=26.4705882352941, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789621, Length=216, Percent_Identity=30.5555555555556, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29540; Mature: 29540

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNTSQQRPYQEVGAMIRDLIVQTPYRPGERLPPEREIAERLNVTRTVVREALIMLEIK
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLVEVRRGAGIYVLDSADNNEMEGADVNHCNDAGPFELLQARQLLESNIAEFAALQATRE
HHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DIIKMRQALQLEERELASSAPGGSESGDMQFHLAIAEATHNSMLVELFRQSWQWRENNPM
HHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCE
WLQLHSHLGDTLYRKEWLVDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
EEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
YFDGYLFESWPLDNVDA
EECCEEECCCCCCCCCC
>Mature Secondary Structure
MKSNTSQQRPYQEVGAMIRDLIVQTPYRPGERLPPEREIAERLNVTRTVVREALIMLEIK
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLVEVRRGAGIYVLDSADNNEMEGADVNHCNDAGPFELLQARQLLESNIAEFAALQATRE
HHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DIIKMRQALQLEERELASSAPGGSESGDMQFHLAIAEATHNSMLVELFRQSWQWRENNPM
HHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCE
WLQLHSHLGDTLYRKEWLVDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
EEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
YFDGYLFESWPLDNVDA
EECCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]