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The map label for this gene is fucK [H]

Identifier: 194735916

GI number: 194735916

Start: 3034372

End: 3035790

Strand: Direct

Name: fucK [H]

Synonym: SeSA_A3139

Alternate gene names: 194735916

Gene position: 3034372-3035790 (Clockwise)

Preceding gene: 194735482

Following gene: 194738148

Centisome position: 64.44

GC content: 58.99

Gene sequence:

>1419_bases
ATGAAACAAGACGTTATCCTGGTTCTCGACTGCGGTGCGACTAACGTTCGGGCGATCGCCGTTGATCGCCAGGGGAAAAT
TGTCGCCCGCGCCTCAACCGCTAACGCCAGCGACATTGCCGCAGAAAATAGCGCCTGGCATCAGTGGTCGCTGGACGCCA
TCCTGCAACGTTTCGCCGACTGCTGCAGGTCACTCTCCAGCGCCCTGTCGGAGTGTGTTGTTCGCGGTATTACGGTGACT
ACGTTCGGCGTCGATGGCGCGCTGGTCGATGCGCAGGGCGAGCTGCTCTACCCGGTCATCAGTTGGAAATGCCCGCGAAC
CGCTGCCGTGATGGAAACGATTGAGCGCTCTATCTCGCCCCGGCAATTGCAGACGCTCTCCGGCGTCGGCGCGTTCAGCT
TTAACACGCTGTATAAACTGGTCTGGCTTAAAGAGAATCATCCGCGCCTGCTGGAACAAGCTCACTGCTGGCTGTTTATC
TCGTCGCTGATTAACCACCGTCTGACCGGCGAGTTTACGACCGATATCACTATGGCAGGCACCAGCCAGCTACTGGATAT
CCATCAGCGCGACTTTAGTCCGGAAATCCTGCAGGCGACGGGCCTGGCGCGCCGCCTGTTCCCGCGTATCGTGGAAGCGG
GCGCCCAGATAGGCACGCTACAGACAGACGCGGCCAGGCTACTCGGTCTCCCGGCGGGTGTGCCGGTGATCTCTGCCGGA
CACGATACTCAGTTCGCGTTATTCGGCGCTGGCGCGCAGCAAGGTGAACCGGTGCTCTCCTCAGGAACATGGGAGATTCT
GATGGTGCGCAGCGGTCAGGTGGATACCTCGCTGCTCAGCCAGTATCCAGGCTCGACCTGTGAACTGGACAGTCAGTCGG
GGCTTTATAACCCCGGAATGCAGTGGCTGGCCTCCGGCGTACTCGAATGGGTACGAAAACTGCTGTGGACGCCGGAAACG
CCATGGCAAACGCTGATCGACGAAGCGCGCGCTATTCCCGCTGGCGCGGAAGGCGTGCGGATGCAGTGCGATCTGCTTGC
CTGCCAAAATGCAGGCTGGCAGGGCGTGACGCTCAATACCACCCGCGGCCATTTCTATCGCGCCGCGCTGGAAGGCCTGA
CGGCGCAACTGCAACGTAATCTGCGCACGCTGGAGAAAATCGGCCATTTTAACACCACAGAACTGTTACTGGTTGGCGGC
GGCAGTCGCAACGCTTTATGGAATCAAATTAAAGCGAATCAGCTTGCTCTCCCTATCAAGGTGCTGGACGACGCGGAAAC
CACCGTGGCCGGCGCTGCCATGTTTGGCTGGTACGGCGTAGGCGAATTTAATAGCCCGGAACAGGCGCGTGCGCAGGTCA
ATTATCAGTATCGCTATTTCTGGCCGCAAACCGAACCTGAAATTATTGAGGGAGTATGA

Upstream 100 bases:

>100_bases
TGCGGCTTAGCCCGGTGGCGCAGGCTTACCGGGCCTACGGGCGCGTGAACCGTAGGCCGGATAAGCGTAGCGCCATCGGG
CGGCGTTTATGGAGTTATCT

Downstream 100 bases:

>100_bases
AATGCTAAAAACCATTTCACCGTTAATTTCCCCGACACTGCTCAAAGTGCTGGCCGAGATGGGCCACGGGGACGAAATCA
TTTTTTCCGACGCTCACTTT

Product: L-fuculokinase

Products: NA

Alternate protein names: L-fuculose kinase [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFADCCRSLSSALSECVVRGITVT
TFGVDGALVDAQGELLYPVISWKCPRTAAVMETIERSISPRQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFI
SSLINHRLTGEFTTDITMAGTSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAQIGTLQTDAARLLGLPAGVPVISAG
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGMQWLASGVLEWVRKLLWTPET
PWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLRTLEKIGHFNTTELLLVGG
GSRNALWNQIKANQLALPIKVLDDAETTVAGAAMFGWYGVGEFNSPEQARAQVNYQYRYFWPQTEPEIIEGV

Sequences:

>Translated_472_residues
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFADCCRSLSSALSECVVRGITVT
TFGVDGALVDAQGELLYPVISWKCPRTAAVMETIERSISPRQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFI
SSLINHRLTGEFTTDITMAGTSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAQIGTLQTDAARLLGLPAGVPVISAG
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGMQWLASGVLEWVRKLLWTPET
PWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLRTLEKIGHFNTTELLLVGG
GSRNALWNQIKANQLALPIKVLDDAETTVAGAAMFGWYGVGEFNSPEQARAQVNYQYRYFWPQTEPEIIEGV
>Mature_472_residues
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFADCCRSLSSALSECVVRGITVT
TFGVDGALVDAQGELLYPVISWKCPRTAAVMETIERSISPRQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFI
SSLINHRLTGEFTTDITMAGTSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAQIGTLQTDAARLLGLPAGVPVISAG
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGMQWLASGVLEWVRKLLWTPET
PWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLRTLEKIGHFNTTELLLVGG
GSRNALWNQIKANQLALPIKVLDDAETTVAGAAMFGWYGVGEFNSPEQARAQVNYQYRYFWPQTEPEIIEGV

Specific function: Fucose metabolism; second step. [C]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789168, Length=472, Percent_Identity=84.5338983050847, Blast_Score=843, Evalue=0.0,
Organism=Escherichia coli, GI1787789, Length=468, Percent_Identity=22.6495726495727, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789987, Length=414, Percent_Identity=25.6038647342995, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1790338, Length=420, Percent_Identity=24.5238095238095, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1790005, Length=489, Percent_Identity=23.3128834355828, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789138, Length=324, Percent_Identity=25, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR013450 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.51 [H]

Molecular weight: Translated: 51659; Mature: 51659

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFAD
CCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCCHHHCCCCCCCCEECHHHHHHHHHH
CCRSLSSALSECVVRGITVTTFGVDGALVDAQGELLYPVISWKCPRTAAVMETIERSISP
HHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCH
RQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFISSLINHRLTGEFTTDITMAG
HHHHHHHCCCCHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEECEEEECC
TSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAQIGTLQTDAARLLGLPAGVPVISAG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCEEECC
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGM
CCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCEECCCCCCCCCCHH
QWLASGVLEWVRKLLWTPETPWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCEEEEC
TRGHFYRAALEGLTAQLQRNLRTLEKIGHFNTTELLLVGGGSRNALWNQIKANQLALPIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHCCCCEEEEEE
VLDDAETTVAGAAMFGWYGVGEFNSPEQARAQVNYQYRYFWPQTEPEIIEGV
EECCCCHHHHHHHHHHEECCCCCCCCHHHHHEEEEEEEEECCCCCCHHHCCC
>Mature Secondary Structure
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFAD
CCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCCHHHCCCCCCCCEECHHHHHHHHHH
CCRSLSSALSECVVRGITVTTFGVDGALVDAQGELLYPVISWKCPRTAAVMETIERSISP
HHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCH
RQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFISSLINHRLTGEFTTDITMAG
HHHHHHHCCCCHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEECEEEECC
TSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAQIGTLQTDAARLLGLPAGVPVISAG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCEEECC
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGM
CCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCEECCCCCCCCCCHH
QWLASGVLEWVRKLLWTPETPWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCEEEEC
TRGHFYRAALEGLTAQLQRNLRTLEKIGHFNTTELLLVGGGSRNALWNQIKANQLALPIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHCCCCEEEEEE
VLDDAETTVAGAAMFGWYGVGEFNSPEQARAQVNYQYRYFWPQTEPEIIEGV
EECCCCHHHHHHHHHHEECCCCCCCCHHHHHEEEEEEEEECCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]