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The map label for this gene is norW [H]

Identifier: 194735906

GI number: 194735906

Start: 2893701

End: 2894834

Strand: Direct

Name: norW [H]

Synonym: SeSA_A2992

Alternate gene names: 194735906

Gene position: 2893701-2894834 (Clockwise)

Preceding gene: 194736009

Following gene: 194737881

Centisome position: 61.45

GC content: 56.26

Gene sequence:

>1134_bases
ATGAGTCGGGGGATCATCATTATTGGATCGGGCTTCGCCGCCCGCCAGCTCGTCAAAAATATCCGTAAACAAGATGCGCA
TGTGCCGTTAACCCTGATTGCGGCGGACAGTATGGATGAGTACAACAAGCCCGATCTCAGCCACGTTATCAGCCAGTCGC
AGCGCGCCGATGATCTCACCCGCCAGTTAGCGGGGGAATTTGCTGAACAGTTTAATCTGCGACTGTTCCCGCATACCTGG
GTTGCTGACATTGATGCCGATGCCCATGTGGTGAAAAGTCAGGATAAGCAGTGGCAGTACGACAAGCTGGTACTGGCGAC
CGGGGCGACAGCCTTTGTACCGCCGATTACAGGACGTGAGTTAATGCTTACTTTGAATAGCCAGCAGGAGTACCGCGCCT
GTGAGACACAACTGCGCGACGCGCAGCGAGTGATGATTGTCGGCGGCGGTCTCATTGGCAGTGAATTAGCGATGGATTTC
TGCCGCGCCGGGAAAACGGTAACGTTGATGGATAACGCCGCCAGCCTTCTCGCCTCACTGATGCCACCGGAAGTGAGCAG
TCGCTTACAGCATCACCTGACCGATATGGGGGTGCATCTGCTGCTGAAATCGCAGTTGCAAAAACTGGAGAAAACCGAAG
CCGGTATCCGCGCTACGCTGGTAAGCCAGCGTAATATTGAGGTCGATGCGGTGATTGCCGCCACCGGCTTACGCCCGGAA
ACCGCTCTGGCGCGCCGCGCCGGGGTAGCCGTCAACCGCGGCGTCTGCGTGGATAGCTATCTACAGACCAGTCACCCGGA
TATTTATGCGATCGGCGACTGCGCGGAGATCAACGGTCAGGTGCTGCCCTTCCTGCAACCGATCCAGTTAAGTGCGATGT
ACCTGGCGAAAAATCTGCTCGGCGGCAACGCGCCGCTGAAGCTACCGGCGATGCTGGTCAAAGTCAAAACGCCGGAACTG
CCGCTGCATCTGGCGGGAGAAACTCAGCGCCGTGATTTAAGCTGGCAGATTACCGCAGAATCTGACGGTATGATTGCCAA
AGGCATGAGCGGAGAAGGCCAACTACGCGCCTTTGTGGTGAGTGAAGACCGCATGAAAGAGGCCTTTGCACTACTGAAAA
CGTTGTCCGTATAA

Upstream 100 bases:

>100_bases
TCGCGCCGGGTACGCCGTGGAGCGACGTGCCAGATAACTTCCTGTGCCCGGAATGTTCATTAGGTAAAGACGTGTTCGAC
GTACTGGCGACGGAGGCAAA

Downstream 100 bases:

>100_bases
GCCTGTGATGCCGGATGGCGCCGCTTCGCGTCTTATCCGGCCCACGAGTGAGCATCTATTTACAGGCCGAATAAGGCGCA
GCCGCCATCCGGCGCCCTAC

Product: nitric oxide reductase

Products: NAD; reduced flavorubredoxin; H2O [C]

Alternate protein names: Flavorubredoxin reductase; FlRd-reductase; FlavoRb reductase [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKPDLSHVISQSQRADDLTRQLAGEFAEQFNLRLFPHTW
VADIDADAHVVKSQDKQWQYDKLVLATGATAFVPPITGRELMLTLNSQQEYRACETQLRDAQRVMIVGGGLIGSELAMDF
CRAGKTVTLMDNAASLLASLMPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKTEAGIRATLVSQRNIEVDAVIAATGLRPE
TALARRAGVAVNRGVCVDSYLQTSHPDIYAIGDCAEINGQVLPFLQPIQLSAMYLAKNLLGGNAPLKLPAMLVKVKTPEL
PLHLAGETQRRDLSWQITAESDGMIAKGMSGEGQLRAFVVSEDRMKEAFALLKTLSV

Sequences:

>Translated_377_residues
MSRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKPDLSHVISQSQRADDLTRQLAGEFAEQFNLRLFPHTW
VADIDADAHVVKSQDKQWQYDKLVLATGATAFVPPITGRELMLTLNSQQEYRACETQLRDAQRVMIVGGGLIGSELAMDF
CRAGKTVTLMDNAASLLASLMPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKTEAGIRATLVSQRNIEVDAVIAATGLRPE
TALARRAGVAVNRGVCVDSYLQTSHPDIYAIGDCAEINGQVLPFLQPIQLSAMYLAKNLLGGNAPLKLPAMLVKVKTPEL
PLHLAGETQRRDLSWQITAESDGMIAKGMSGEGQLRAFVVSEDRMKEAFALLKTLSV
>Mature_376_residues
SRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKPDLSHVISQSQRADDLTRQLAGEFAEQFNLRLFPHTWV
ADIDADAHVVKSQDKQWQYDKLVLATGATAFVPPITGRELMLTLNSQQEYRACETQLRDAQRVMIVGGGLIGSELAMDFC
RAGKTVTLMDNAASLLASLMPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKTEAGIRATLVSQRNIEVDAVIAATGLRPET
ALARRAGVAVNRGVCVDSYLQTSHPDIYAIGDCAEINGQVLPFLQPIQLSAMYLAKNLLGGNAPLKLPAMLVKVKTPELP
LHLAGETQRRDLSWQITAESDGMIAKGMSGEGQLRAFVVSEDRMKEAFALLKTLSV

Specific function: One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=281, Percent_Identity=22.0640569395018, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI21389617, Length=281, Percent_Identity=22.0640569395018, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI65787454, Length=281, Percent_Identity=22.0640569395018, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1789065, Length=375, Percent_Identity=85.8666666666667, Blast_Score=670, Evalue=0.0,
Organism=Escherichia coli, GI1789765, Length=321, Percent_Identity=26.791277258567, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788892, Length=276, Percent_Identity=27.536231884058, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787352, Length=251, Percent_Identity=28.2868525896414, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=317, Percent_Identity=22.397476340694, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639257, Length=284, Percent_Identity=25.3521126760563, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281359715, Length=284, Percent_Identity=25.3521126760563, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281359713, Length=284, Percent_Identity=25.3521126760563, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24639250, Length=284, Percent_Identity=25.3521126760563, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI18543267, Length=284, Percent_Identity=25.3521126760563, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24639252, Length=284, Percent_Identity=25.3521126760563, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 41215; Mature: 41084

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKPDLSHVISQSQRADDLT
CCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
RQLAGEFAEQFNLRLFPHTWVADIDADAHVVKSQDKQWQYDKLVLATGATAFVPPITGRE
HHHHHHHHHHCCCEECCCCEEEECCCCHHHHCCCCCCCCCCEEEEEECCCEECCCCCCCE
LMLTLNSQQEYRACETQLRDAQRVMIVGGGLIGSELAMDFCRAGKTVTLMDNAASLLASL
EEEEECCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCEEEEECHHHHHHHHH
MPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKTEAGIRATLVSQRNIEVDAVIAATGLRPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEEECCCCCH
TALARRAGVAVNRGVCVDSYLQTSHPDIYAIGDCAEINGQVLPFLQPIQLSAMYLAKNLL
HHHHHHCCCEECCCCCHHHHHHCCCCCEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHH
GGNAPLKLPAMLVKVKTPELPLHLAGETQRRDLSWQITAESDGMIAKGMSGEGQLRAFVV
CCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCEEEEEECCCCCEEECCCCCCCEEEEEE
SEDRMKEAFALLKTLSV
CHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKPDLSHVISQSQRADDLT
CCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
RQLAGEFAEQFNLRLFPHTWVADIDADAHVVKSQDKQWQYDKLVLATGATAFVPPITGRE
HHHHHHHHHHCCCEECCCCEEEECCCCHHHHCCCCCCCCCCEEEEEECCCEECCCCCCCE
LMLTLNSQQEYRACETQLRDAQRVMIVGGGLIGSELAMDFCRAGKTVTLMDNAASLLASL
EEEEECCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCEEEEECHHHHHHHHH
MPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKTEAGIRATLVSQRNIEVDAVIAATGLRPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEEECCCCCH
TALARRAGVAVNRGVCVDSYLQTSHPDIYAIGDCAEINGQVLPFLQPIQLSAMYLAKNLL
HHHHHHCCCEECCCCCHHHHHHCCCCCEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHH
GGNAPLKLPAMLVKVKTPELPLHLAGETQRRDLSWQITAESDGMIAKGMSGEGQLRAFVV
CCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCEEEEEECCCCCEEECCCCCCCEEEEEE
SEDRMKEAFALLKTLSV
CHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; oxidized flavorubredoxin; O2 [C]

Specific reaction: NADH + oxidized flavorubredoxin + O2 = NAD + reduced flavorubredoxin + H2O [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA