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The map label for this gene is yeeF [H]

Identifier: 194735873

GI number: 194735873

Start: 2165105

End: 2166463

Strand: Reverse

Name: yeeF [H]

Synonym: SeSA_A2295

Alternate gene names: 194735873

Gene position: 2166463-2165105 (Counterclockwise)

Preceding gene: 194737070

Following gene: 194734635

Centisome position: 46.01

GC content: 53.57

Gene sequence:

>1359_bases
ATGTCGCATAACGTTACTCCAAACACCTCTCGCGTGGAATTACGTAAAACGCTTACGTTAGTTCCGGTTGTAATGATGGG
TCTTGCCTATATGCAGCCGATGACGCTGTTCGATACATTTGGTATCGTTTCAGGCCTCACTGACGGTCACGTACCGACGG
CGTATGCATTCGCGTTAATCGCGATTCTGTTTACGGCGTTGAGCTACGGGAAACTGGTGCGTCGCTACCCTTCCGCGGGT
TCGGCGTACACCTATGCCCAGAAATCCATCAGCCCGACCGTTGGCTTTATGGTGGGTTGGTCTTCTCTGCTCGATTATCT
GTTCGCGCCGATGATCAACATTCTGTTGGCGAAAATTTATTTTGAAGCGCTGGTGCCCTCCATTCCGTCATGGGTGTTTG
TCGTGGCGCTGGTGGCCTTTATGACGGCCTTTAACCTGCGCAGCCTCAAATCGGTCGCTAACTTCAACACCGTGATTGTA
GTGCTACAGGTGGTGCTGATTGCGGTCATTCTGGGCATGGTGGTTTATGGCGTATTTGAAGGCGAAGGCGCCGGTACGCT
GGCGAGCACCCGTCCGTTCTGGTCCGGCGATGCGCACGTTATCCCGATGATTACGGGAGCGACGATCCTGTGCTTCTCCT
TTACCGGCTTTGACGGCATCAGTAACCTGTCGGAAGAGACCAAAGATGCTGAACGCGTGATCCCGCGTGCGATTTTCCTG
ACCGCGCTGATTGGCGGCCTGATCTTCATCTTTGCAACCTATTTCCTGCAATTGTACTTCCCGGATATCTCTCGCTTTAA
AGATCCGGATGCGTCTCAGCCGGAAATCATGCTGTACGTGGCGGGTAAAACCTTCCAGGTTGGTGCGCTGATCTTCTCTA
CTATCACCGTGCTGGCTTCCGGTATGGCGGCGCATGCAGGCGTAGCGCGCCTGATGTACGTAATGGGGCGTGACGGCGTA
TTCCCGAAAAGCTTCTTCGGTTACGTTCATCCGAAATGGCGTACGCCAGCGATGAACATCATCCTGGTCGGGGCGATCGC
GCTGCTGGCGATTAATTTTGACCTGGTGATGGCGACGGCGCTGATTAACTTTGGTGCGCTGGTCGCGTTTACCTTCGTTA
ACCTGTCGGTGATTTCGCAGTTCTGGATCCGTGAGAAGCGTAATAAAACGTTGAAAGATCACTTCCAGTATCTGTTCCTG
CCTATGTGCGGTGCGCTCACGGTTGGTGCGTTGTGGGTTAACCTGGAAGAGAGCTCAATGGTACTGGGCCTGATCTGGGC
GGGTATCGGGCTGATTTATCTGGCGTGCGTAACTAAAAGCTTCCGCAACCCGGTTCCACAGTACGAAGACGTCGCGTAA

Upstream 100 bases:

>100_bases
GATACTTACTTAAAAATCGACAGTTGTTGTCGCTGAGGAATCCAGAAAATGGGGCAATTTTTTGCTTACGCGACGGCATT
CGCCGTAAAGGAGAATGACC

Downstream 100 bases:

>100_bases
TCGCGCGTATTATTGGTAATAGTAAAACCGGAGGCAGTGCCTCCGGTTTTTTGTTTGTCATCCAGCATGTTTACCGGATG
GCGGCGTCACTCTTTATCCG

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVSGLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAG
SAYTYAQKSISPTVGFMVGWSSLLDYLFAPMINILLAKIYFEALVPSIPSWVFVVALVAFMTAFNLRSLKSVANFNTVIV
VLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFDGISNLSEETKDAERVIPRAIFL
TALIGGLIFIFATYFLQLYFPDISRFKDPDASQPEIMLYVAGKTFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGV
FPKSFFGYVHPKWRTPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLKDHFQYLFL
PMCGALTVGALWVNLEESSMVLGLIWAGIGLIYLACVTKSFRNPVPQYEDVA

Sequences:

>Translated_452_residues
MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVSGLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAG
SAYTYAQKSISPTVGFMVGWSSLLDYLFAPMINILLAKIYFEALVPSIPSWVFVVALVAFMTAFNLRSLKSVANFNTVIV
VLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFDGISNLSEETKDAERVIPRAIFL
TALIGGLIFIFATYFLQLYFPDISRFKDPDASQPEIMLYVAGKTFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGV
FPKSFFGYVHPKWRTPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLKDHFQYLFL
PMCGALTVGALWVNLEESSMVLGLIWAGIGLIYLACVTKSFRNPVPQYEDVA
>Mature_451_residues
SHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVSGLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAGS
AYTYAQKSISPTVGFMVGWSSLLDYLFAPMINILLAKIYFEALVPSIPSWVFVVALVAFMTAFNLRSLKSVANFNTVIVV
LQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFDGISNLSEETKDAERVIPRAIFLT
ALIGGLIFIFATYFLQLYFPDISRFKDPDASQPEIMLYVAGKTFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVF
PKSFFGYVHPKWRTPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLKDHFQYLFLP
MCGALTVGALWVNLEESSMVLGLIWAGIGLIYLACVTKSFRNPVPQYEDVA

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=422, Percent_Identity=22.7488151658768, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI186910308, Length=415, Percent_Identity=23.6144578313253, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI186910306, Length=415, Percent_Identity=23.6144578313253, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI186910304, Length=415, Percent_Identity=23.6144578313253, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI181337167, Length=401, Percent_Identity=23.1920199501247, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87082023, Length=452, Percent_Identity=99.1150442477876, Blast_Score=908, Evalue=0.0,
Organism=Escherichia coli, GI87081869, Length=446, Percent_Identity=63.9013452914798, Blast_Score=589, Evalue=1e-169,
Organism=Escherichia coli, GI87082250, Length=328, Percent_Identity=24.6951219512195, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786602, Length=271, Percent_Identity=24.7232472324723, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786789, Length=362, Percent_Identity=23.4806629834254, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790653, Length=352, Percent_Identity=23.0113636363636, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788480, Length=335, Percent_Identity=22.9850746268657, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786302, Length=288, Percent_Identity=24.3055555555556, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=402, Percent_Identity=26.3681592039801, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17533459, Length=399, Percent_Identity=27.3182957393484, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17531343, Length=404, Percent_Identity=26.980198019802, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24667468, Length=408, Percent_Identity=26.9607843137255, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24668806, Length=420, Percent_Identity=26.9047619047619, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21356285, Length=420, Percent_Identity=26.9047619047619, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24668802, Length=420, Percent_Identity=26.9047619047619, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24666159, Length=422, Percent_Identity=23.696682464455, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221512776, Length=422, Percent_Identity=23.696682464455, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281366235, Length=352, Percent_Identity=25, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI116007820, Length=352, Percent_Identity=25, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI116007818, Length=352, Percent_Identity=25, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI85725152, Length=352, Percent_Identity=25, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49504; Mature: 49373

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVSGLTDGHVPTAYAFALI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSSLLDYLFAPMINILLAKIY
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEALVPSIPSWVFVVALVAFMTAFNLRSLKSVANFNTVIVVLQVVLIAVILGMVVYGVFE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFDGISNLSEETKDAERVIPRAIFL
CCCCCCCCCCCCCCCCCCEEEEEHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
TALIGGLIFIFATYFLQLYFPDISRFKDPDASQPEIMLYVAGKTFQVGALIFSTITVLAS
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
GMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWRTPAMNIILVGAIALLAINFDLVMATA
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LINFGALVAFTFVNLSVISQFWIREKRNKTLKDHFQYLFLPMCGALTVGALWVNLEESSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHH
VLGLIWAGIGLIYLACVTKSFRNPVPQYEDVA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVSGLTDGHVPTAYAFALI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSSLLDYLFAPMINILLAKIY
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEALVPSIPSWVFVVALVAFMTAFNLRSLKSVANFNTVIVVLQVVLIAVILGMVVYGVFE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFDGISNLSEETKDAERVIPRAIFL
CCCCCCCCCCCCCCCCCCEEEEEHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
TALIGGLIFIFATYFLQLYFPDISRFKDPDASQPEIMLYVAGKTFQVGALIFSTITVLAS
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
GMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWRTPAMNIILVGAIALLAINFDLVMATA
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LINFGALVAFTFVNLSVISQFWIREKRNKTLKDHFQYLFLPMCGALTVGALWVNLEESSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHH
VLGLIWAGIGLIYLACVTKSFRNPVPQYEDVA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]