Click here to switch to the map view.

The map label for this gene is sgrR [H]

Identifier: 194735782

GI number: 194735782

Start: 126790

End: 128448

Strand: Reverse

Name: sgrR [H]

Synonym: SeSA_A0122

Alternate gene names: 194735782

Gene position: 128448-126790 (Counterclockwise)

Preceding gene: 194737348

Following gene: 194734268

Centisome position: 2.73

GC content: 56.66

Gene sequence:

>1659_bases
ATGCCCTCAGGTCGCCTGCAACAACAATTTATCCGTCTCTGGCAATGTTGTGACGGTAAAACGCAAGACACCACGCTTAA
TGAGCTGGCGGATCTGCTGAACTGTTCGCGTCGCCATATGCGTACGCTGCTAAATACGATGCAGGCGCGCGGTTGGCTAA
CATGGGAAGCCGAGGTTGGACGCGGAAAGCGTTCGCGTCTGACGTTCCTGTATACCGGACTGGCGCTGCAACAGCAGCGG
GCGGAAGACCTGCTGGAACAAGATCGAATCGATCAACTGGTACAACTGGTCGGCGATAAAAGCGCTGTCAGGCAAATGCT
GATTTCCCATCTGGGACGCAGCTTCCGCCAGGGGCGGCATATTCTGCGGGTTCTTTACTATCGTCCGATGCACAATCTCC
TGCCGGGAACCGCATTACGTCGCTCGGAAACCCATATTGCCCGGCAAATTTTCAGTTCGCTCACGCGGGTAAATGAGGAA
AACGGGGAACTGGAAGCGGACATTGCGCACCACTGGCAGCAAATTTCCCCTTTACTGTGGCGCTTCTACCTGCGCCCCGG
CATTCATTTTCATCATGGCCGCGAGCTGGAGATGGAAGATGTCATCGCCTCGCTGACGCGTATCAATACGCTTCCACTTT
ACTCGCACATCACAAAGATAGACTCCCCTACCGCGTGGACGCTGGATATTCATCTTTCCCAGCCGGATCGTTGGTTGCCG
TGGCTGCTGGGCCAGGTCCCGGCGATGATTTTGCCGCGGGAGTGGGAAACGCTGGCTAATTTCGCCAGCCACCCTATCGG
CACCGGGCCTTATGCCGTGCGGCGTAATACGCCGAACCAACTCAAGATACTCGCCTTTGATGACTACTTCGGCTATCGAG
CGTTAATAGACGAAGTGAACGTCTGGGTACTGCCGGATATCAGTGAAGAACCGGCCTGCGGCTTGATGCTGGAAGGGCCG
ATACAAGGCGGTGAAAAAGCGATAGAAAGCCGACTGGAAGAGGGGTGCTATTACCTGCTATTCGACGCCAGAACGCCGCG
CGGCGCGCATCCGCAGGTCAGAGAATGGGTAAGCCACGTCCTCTCCCCCACCAATTTACTCTATCATGCCGATGAACCGC
TACAGCAGCTCTGGTTCCCGGCCTATGGGCTTTTACCGCGCTGGCATCACGCCCGTCCAGGCCCGGGCGAAAAACCCGCC
GGTCTGGAAACCCTCACGCTGACCTTCTATCGCGAACACATTGAGCACCGGGTTATCGCCCGTATCATGAGCGCGCTTCT
GGCTGAACATCAGGTGCATTTGCATATTCAGGAGATCGACTACGATCAATGGCACGCCGGCGAGATCGAAAGCGATATCT
GGCTCAATAGCGCTAACTTTACGCTGCCGCTGGATTTCTCGCTGTTCGCGCACCTGTGCGAAGTACCGCTCTTGCAGAAC
TGCATTCCGCGCGACTGGCAGGACGACGCCGCACAGTGGCGCGCTGGCGAGATGAACCTGGCGAACTGGTGCCAGCAACT
GCTGGCCAACAAAGCGATTGTGCCGCTGATCCACCACTGGCTGATTATCCAGGGACAGCGCAGTATGCGCGGGCTGCGCA
TGAATACCCTCGGCTGGTTTGATTTTAAATCGGCGTGGTTTGCGCCGCCAGATCCTTAA

Upstream 100 bases:

>100_bases
TGGTGCATAGTGACCTCTTCCTCTTGCTTCATCGAAAGATATTATTGGCCTAATATAGGGATAATAAAATTGCTGAGTTT
TTCATCGGAGTTCCCCTTTT

Downstream 100 bases:

>100_bases
CGCCAGCTCTTGATTGCTGCCCGGCAACAAAATCACTACACTAACGCCGAACTCAACGGGGTGCCGCGCTCATGCGCGCG
CTGAGAAAATACCCGTCGAA

Product: transcriptional regulator SgrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MPSGRLQQQFIRLWQCCDGKTQDTTLNELADLLNCSRRHMRTLLNTMQARGWLTWEAEVGRGKRSRLTFLYTGLALQQQR
AEDLLEQDRIDQLVQLVGDKSAVRQMLISHLGRSFRQGRHILRVLYYRPMHNLLPGTALRRSETHIARQIFSSLTRVNEE
NGELEADIAHHWQQISPLLWRFYLRPGIHFHHGRELEMEDVIASLTRINTLPLYSHITKIDSPTAWTLDIHLSQPDRWLP
WLLGQVPAMILPREWETLANFASHPIGTGPYAVRRNTPNQLKILAFDDYFGYRALIDEVNVWVLPDISEEPACGLMLEGP
IQGGEKAIESRLEEGCYYLLFDARTPRGAHPQVREWVSHVLSPTNLLYHADEPLQQLWFPAYGLLPRWHHARPGPGEKPA
GLETLTLTFYREHIEHRVIARIMSALLAEHQVHLHIQEIDYDQWHAGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQN
CIPRDWQDDAAQWRAGEMNLANWCQQLLANKAIVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP

Sequences:

>Translated_552_residues
MPSGRLQQQFIRLWQCCDGKTQDTTLNELADLLNCSRRHMRTLLNTMQARGWLTWEAEVGRGKRSRLTFLYTGLALQQQR
AEDLLEQDRIDQLVQLVGDKSAVRQMLISHLGRSFRQGRHILRVLYYRPMHNLLPGTALRRSETHIARQIFSSLTRVNEE
NGELEADIAHHWQQISPLLWRFYLRPGIHFHHGRELEMEDVIASLTRINTLPLYSHITKIDSPTAWTLDIHLSQPDRWLP
WLLGQVPAMILPREWETLANFASHPIGTGPYAVRRNTPNQLKILAFDDYFGYRALIDEVNVWVLPDISEEPACGLMLEGP
IQGGEKAIESRLEEGCYYLLFDARTPRGAHPQVREWVSHVLSPTNLLYHADEPLQQLWFPAYGLLPRWHHARPGPGEKPA
GLETLTLTFYREHIEHRVIARIMSALLAEHQVHLHIQEIDYDQWHAGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQN
CIPRDWQDDAAQWRAGEMNLANWCQQLLANKAIVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP
>Mature_551_residues
PSGRLQQQFIRLWQCCDGKTQDTTLNELADLLNCSRRHMRTLLNTMQARGWLTWEAEVGRGKRSRLTFLYTGLALQQQRA
EDLLEQDRIDQLVQLVGDKSAVRQMLISHLGRSFRQGRHILRVLYYRPMHNLLPGTALRRSETHIARQIFSSLTRVNEEN
GELEADIAHHWQQISPLLWRFYLRPGIHFHHGRELEMEDVIASLTRINTLPLYSHITKIDSPTAWTLDIHLSQPDRWLPW
LLGQVPAMILPREWETLANFASHPIGTGPYAVRRNTPNQLKILAFDDYFGYRALIDEVNVWVLPDISEEPACGLMLEGPI
QGGEKAIESRLEEGCYYLLFDARTPRGAHPQVREWVSHVLSPTNLLYHADEPLQQLWFPAYGLLPRWHHARPGPGEKPAG
LETLTLTFYREHIEHRVIARIMSALLAEHQVHLHIQEIDYDQWHAGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQNC
IPRDWQDDAAQWRAGEMNLANWCQQLLANKAIVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP

Specific function: Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding

COG id: COG4533

COG function: function code R; ABC-type uncharacterized transport system, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786256, Length=552, Percent_Identity=86.231884057971, Blast_Score=986, Evalue=0.0,
Organism=Escherichia coli, GI1786650, Length=584, Percent_Identity=29.2808219178082, Blast_Score=183, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 64039; Mature: 63908

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSGRLQQQFIRLWQCCDGKTQDTTLNELADLLNCSRRHMRTLLNTMQARGWLTWEAEVG
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCC
RGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKSAVRQMLISHLGRSFRQGRH
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ILRVLYYRPMHNLLPGTALRRSETHIARQIFSSLTRVNEENGELEADIAHHWQQISPLLW
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHH
RFYLRPGIHFHHGRELEMEDVIASLTRINTLPLYSHITKIDSPTAWTLDIHLSQPDRWLP
HHHHCCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEEECCCCCHHH
WLLGQVPAMILPREWETLANFASHPIGTGPYAVRRNTPNQLKILAFDDYFGYRALIDEVN
HHHHCCCHHCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEECCCCHHHHHHCCC
VWVLPDISEEPACGLMLEGPIQGGEKAIESRLEEGCYYLLFDARTPRGAHPQVREWVSHV
EEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH
LSPTNLLYHADEPLQQLWFPAYGLLPRWHHARPGPGEKPAGLETLTLTFYREHIEHRVIA
CCHHHEEEECCCHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RIMSALLAEHQVHLHIQEIDYDQWHAGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQN
HHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEECHHHHHHHHCCHHHHH
CIPRDWQDDAAQWRAGEMNLANWCQQLLANKAIVPLIHHWLIIQGQRSMRGLRMNTLGWF
CCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHEECCHHHCCCEECCCCCC
DFKSAWFAPPDP
CCCCCCCCCCCC
>Mature Secondary Structure 
PSGRLQQQFIRLWQCCDGKTQDTTLNELADLLNCSRRHMRTLLNTMQARGWLTWEAEVG
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCC
RGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKSAVRQMLISHLGRSFRQGRH
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ILRVLYYRPMHNLLPGTALRRSETHIARQIFSSLTRVNEENGELEADIAHHWQQISPLLW
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHH
RFYLRPGIHFHHGRELEMEDVIASLTRINTLPLYSHITKIDSPTAWTLDIHLSQPDRWLP
HHHHCCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEEECCCCCHHH
WLLGQVPAMILPREWETLANFASHPIGTGPYAVRRNTPNQLKILAFDDYFGYRALIDEVN
HHHHCCCHHCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEECCCCHHHHHHCCC
VWVLPDISEEPACGLMLEGPIQGGEKAIESRLEEGCYYLLFDARTPRGAHPQVREWVSHV
EEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH
LSPTNLLYHADEPLQQLWFPAYGLLPRWHHARPGPGEKPAGLETLTLTFYREHIEHRVIA
CCHHHEEEECCCHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RIMSALLAEHQVHLHIQEIDYDQWHAGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQN
HHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEECHHHHHHHHCCHHHHH
CIPRDWQDDAAQWRAGEMNLANWCQQLLANKAIVPLIHHWLIIQGQRSMRGLRMNTLGWF
CCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHEECCHHHCCCEECCCCCC
DFKSAWFAPPDP
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA