| Definition | Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633 chromosome, complete genome. |
|---|---|
| Accession | NC_011094 |
| Length | 4,709,075 |
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The map label for this gene is rnr [H]
Identifier: 194735764
GI number: 194735764
Start: 4510359
End: 4512797
Strand: Direct
Name: rnr [H]
Synonym: SeSA_A4636
Alternate gene names: 194735764
Gene position: 4510359-4512797 (Clockwise)
Preceding gene: 194735133
Following gene: 194734163
Centisome position: 95.78
GC content: 55.19
Gene sequence:
>2439_bases ATGTCACAAGATCCTTTCCAGGAACGCGAAGCAGAAAAATACGCGAATCCTATCCCGAGCCGGGAATTTATCCTCGAACA TTTAACGAAACGTGAAAAACCGGCCAGTCGCGAAGAACTGGCCGTAGAACTGAATATTGAAGGCGAAGAGCAGCTTGAAG CCTTGCGTCGCCGCCTGCGCGCGATGGAGCGCGACGGACAACTGGTCTTTACCCGCCGCCAGTGCTATGCGCTGCCGGAA CGCCTCGACCTGCTGAAAGGCACCGTGATCGGTCATCGTGATGGTTACGGTTTCTTACGTGTCGAAGGCCGCAAAGACGA TCTGTATCTTTCCAGCGAGCAAATGAAAACCTGTATTCATGGCGATCAGGTGCTGGCGCAGCCGCTGGGCGCCGATCGTA AAGGTCGCCGCGAAGCGCGTATCGTCCGTGTACTGGTACCGAAAACCAGTCAGATAGTCGGGCGTTATTTCACCGATGCG GGCGTCGGCTTTGTAGTGCCGGACGACAGCCGTCTCAGCTTCGACATTCTTATCCCGCCAGAAGACGTCATGGGCGCGCG GATGGGGTTCGTGGTCGTGGTTGAACTGACCCAACGTCCAACTCGCCGTACTAAAGCGGTAGGGAAAATCGTCGAAGTGC TGGGCGACAATATGGGCACCGGTATGGCGGTTGATATGGCGCTTTGTACCCATGAAATACCCTACATCTGGCCGCAGGCG GTAGAGCAGCAGGTCGCCGGGCTGAAAGAAGAGGTGCCGGAAGAGGCGAAAGCCGGTCGTGTCGATCTGCGCGATTTGCC GCTGGTCACGATTGATGGCGAAGATGCCCGTGACTTTGACGACGCGGTTTACTGTGAGAAAAAACGCGGCGGCGGCTGGC GTTTGTGGGTCGCTATTGCTGACGTGAGCTATTATGTACGGCCGCCAACGCCGTTGGATCGCGAGGCGCGCAATCGCGGC ACGTCGGTTTACTTCCCGTCACAGGTTGTCCCAATGTTGCCGGAGGTGCTCTCCAACGGCCTGTGTTCGCTAAACCCGCA GGTTGACAGGCTGTGTATGGTCTGTGAAATGACCATCTCGGCGAAAGGTCGGCTGACCGGCTACAAATTCTATGAAGCGG TGATGAGCTCCCATGCGCGTCTGACCTATACCAAAGTCTGGCATATGCTGCAGGGCGATCAGGATCTGCGTGAACAATAT GCGCCGCTGGTGAAGCATATTGAAGAGCTGCACAACCTCTACAAAGTGCTGGATAAAGCGCGTGAAGAGCGCGGGGGGAT CTCGTTTGAGAGCGAAGAGGCGAAGTTTATCTTTAACGCCGATCGTCGCATTGAGCGTATCGAACAGACCCAGCGTAATG ACGCGCATAAGCTTATCGAAGAGTGCATGATCATGGCGAATATCTCGGCGGCGCGCTTTGTCGAAAAAGCTAAAGAGCCG GCGTTATTCCGTATTCATGATAAGCCCACCACCGAAGCGATCACCTCATTCCGCTCCGTACTGGCGGAGCTGGGGTTGGA GCTGCCGGGCGGAAACAAACCGGAACCGCGCGATTATGCCGAACTGCTTGAATCGATTGCCGACCGGCCGGACGCCGAAA TGCTGCAAACTATGCTGCTGCGTTCAATGAAGCAGGCGATTTACGATCCGGAAAACCGCGGGCACTTTGGCCTGGCGTTG CAGTCTTATGCGCACTTTACCTCGCCGATTCGCCGCTATCCGGATCTTTCTTTGCACCGCGCCATTAAGTACCTGCTGGC GAAAGAGCAAGGGAACAAGGGCAACACCACAGAAACGGGCGGTTATCACTACTCGATGGAAGAGATGTTGCAGCTCGGCC AGCACTGTTCGATGGCGGAACGCCGCGCTGATGAAGCGACGCGTGATGTCTCCGACTGGCTGAAATGTGACTTTATGCTG GATCAGGTAGGCAACGTCTTTAAGGGTGTGATTGCCAGCGTCACCGGTTTCGGCTTCTTTGTCCGTCTTGATGAACTGTT TATCGATGGACTGGTACACGTTTCCTCACTGGATAACGATTACTATCGCTTCGATCAGGTAGGGCAACGTCTGATTGGCG AGTCCGGCGGGCAGACATATCGCCTGGGCGACCGGGTCGAGGTACGTGTCGAAGCGGTGAATATGGACGAACGGAAAATT GACTTTAGCCTGATCTCCAGCGAGCGCGCACCGCGTAACGTCGGCAAAACGGCGCGTGAAAAAGCGAAAAAAGGTGAAAG TAAAAACGCCGGTAAACGTCGTCAGGTAGGTAAAAAAGTTAACTTCGAGCCTGATAGCGCCTTCCGCGGCGAGAAAAAAG CGAAGCCGAAAGCAGCGAAAAAAGACGCGCGAAAAGCAAAAAAGCCATCGGCTAAAACGCAGAAAATAGCCGCAGCGACC AAAGCGAAGCGTGCGGCGAAGAAAAAAGCGGCAGAGTGA
Upstream 100 bases:
>100_bases TACACGCTTGCCGATTTGGTTGAAGAGAATCAACCGCTTTATAAATTATTACTGGTGGAGTGAAGTAAACTTCATTAGAG ATGACAATGGAGGAACCTCA
Downstream 100 bases:
>100_bases GCAATACCCTCTTCAAACAGAAGAGGGTGAATTATCTGTAGGCCGGGCAAGCGTAGCGCCCCCGGCAAAACGTAAACAAT GAGTACATTAATGAGCGAAA
Product: exoribonuclease R
Products: NA
Alternate protein names: RNase R; Protein vacB [H]
Number of amino acids: Translated: 812; Mature: 811
Protein sequence:
>812_residues MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASREELAVELNIEGEEQLEALRRRLRAMERDGQLVFTRRQCYALPE RLDLLKGTVIGHRDGYGFLRVEGRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTDA GVGFVVPDDSRLSFDILIPPEDVMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNMGTGMAVDMALCTHEIPYIWPQA VEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDARDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRG TSVYFPSQVVPMLPEVLSNGLCSLNPQVDRLCMVCEMTISAKGRLTGYKFYEAVMSSHARLTYTKVWHMLQGDQDLREQY APLVKHIEELHNLYKVLDKAREERGGISFESEEAKFIFNADRRIERIEQTQRNDAHKLIEECMIMANISAARFVEKAKEP ALFRIHDKPTTEAITSFRSVLAELGLELPGGNKPEPRDYAELLESIADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLAL QSYAHFTSPIRRYPDLSLHRAIKYLLAKEQGNKGNTTETGGYHYSMEEMLQLGQHCSMAERRADEATRDVSDWLKCDFML DQVGNVFKGVIASVTGFGFFVRLDELFIDGLVHVSSLDNDYYRFDQVGQRLIGESGGQTYRLGDRVEVRVEAVNMDERKI DFSLISSERAPRNVGKTAREKAKKGESKNAGKRRQVGKKVNFEPDSAFRGEKKAKPKAAKKDARKAKKPSAKTQKIAAAT KAKRAAKKKAAE
Sequences:
>Translated_812_residues MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASREELAVELNIEGEEQLEALRRRLRAMERDGQLVFTRRQCYALPE RLDLLKGTVIGHRDGYGFLRVEGRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTDA GVGFVVPDDSRLSFDILIPPEDVMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNMGTGMAVDMALCTHEIPYIWPQA VEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDARDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRG TSVYFPSQVVPMLPEVLSNGLCSLNPQVDRLCMVCEMTISAKGRLTGYKFYEAVMSSHARLTYTKVWHMLQGDQDLREQY APLVKHIEELHNLYKVLDKAREERGGISFESEEAKFIFNADRRIERIEQTQRNDAHKLIEECMIMANISAARFVEKAKEP ALFRIHDKPTTEAITSFRSVLAELGLELPGGNKPEPRDYAELLESIADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLAL QSYAHFTSPIRRYPDLSLHRAIKYLLAKEQGNKGNTTETGGYHYSMEEMLQLGQHCSMAERRADEATRDVSDWLKCDFML DQVGNVFKGVIASVTGFGFFVRLDELFIDGLVHVSSLDNDYYRFDQVGQRLIGESGGQTYRLGDRVEVRVEAVNMDERKI DFSLISSERAPRNVGKTAREKAKKGESKNAGKRRQVGKKVNFEPDSAFRGEKKAKPKAAKKDARKAKKPSAKTQKIAAAT KAKRAAKKKAAE >Mature_811_residues SQDPFQEREAEKYANPIPSREFILEHLTKREKPASREELAVELNIEGEEQLEALRRRLRAMERDGQLVFTRRQCYALPER LDLLKGTVIGHRDGYGFLRVEGRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTDAG VGFVVPDDSRLSFDILIPPEDVMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNMGTGMAVDMALCTHEIPYIWPQAV EQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDARDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGT SVYFPSQVVPMLPEVLSNGLCSLNPQVDRLCMVCEMTISAKGRLTGYKFYEAVMSSHARLTYTKVWHMLQGDQDLREQYA PLVKHIEELHNLYKVLDKAREERGGISFESEEAKFIFNADRRIERIEQTQRNDAHKLIEECMIMANISAARFVEKAKEPA LFRIHDKPTTEAITSFRSVLAELGLELPGGNKPEPRDYAELLESIADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQ SYAHFTSPIRRYPDLSLHRAIKYLLAKEQGNKGNTTETGGYHYSMEEMLQLGQHCSMAERRADEATRDVSDWLKCDFMLD QVGNVFKGVIASVTGFGFFVRLDELFIDGLVHVSSLDNDYYRFDQVGQRLIGESGGQTYRLGDRVEVRVEAVNMDERKID FSLISSERAPRNVGKTAREKAKKGESKNAGKRRQVGKKVNFEPDSAFRGEKKAKPKAAKKDARKAKKPSAKTQKIAAATK AKRAAKKKAAE
Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs. Required for the expression of virulence genes in enteroinvasive strains of E.coli [H]
COG id: COG0557
COG function: function code K; Exoribonuclease R
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 S1 motif domain [H]
Homologues:
Organism=Homo sapiens, GI190014623, Length=402, Percent_Identity=31.3432835820896, Blast_Score=179, Evalue=6e-45, Organism=Homo sapiens, GI190014625, Length=402, Percent_Identity=31.3432835820896, Blast_Score=179, Evalue=8e-45, Organism=Homo sapiens, GI134288890, Length=405, Percent_Identity=30.1234567901235, Blast_Score=167, Evalue=3e-41, Organism=Homo sapiens, GI19115966, Length=526, Percent_Identity=26.425855513308, Blast_Score=143, Evalue=6e-34, Organism=Homo sapiens, GI219521928, Length=526, Percent_Identity=26.425855513308, Blast_Score=142, Evalue=9e-34, Organism=Escherichia coli, GI87082383, Length=795, Percent_Identity=95.2201257861635, Blast_Score=1531, Evalue=0.0, Organism=Escherichia coli, GI1787542, Length=651, Percent_Identity=25.9600614439324, Blast_Score=167, Evalue=3e-42, Organism=Caenorhabditis elegans, GI212645896, Length=407, Percent_Identity=30.4668304668305, Blast_Score=173, Evalue=3e-43, Organism=Caenorhabditis elegans, GI17553506, Length=560, Percent_Identity=27.5, Blast_Score=172, Evalue=8e-43, Organism=Saccharomyces cerevisiae, GI6324552, Length=564, Percent_Identity=26.4184397163121, Blast_Score=152, Evalue=2e-37, Organism=Saccharomyces cerevisiae, GI6323943, Length=358, Percent_Identity=24.5810055865922, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24649634, Length=480, Percent_Identity=28.5416666666667, Blast_Score=176, Evalue=8e-44, Organism=Drosophila melanogaster, GI19922976, Length=361, Percent_Identity=28.808864265928, Blast_Score=142, Evalue=1e-33, Organism=Drosophila melanogaster, GI24654597, Length=361, Percent_Identity=28.808864265928, Blast_Score=142, Evalue=1e-33, Organism=Drosophila melanogaster, GI24654592, Length=361, Percent_Identity=28.808864265928, Blast_Score=141, Evalue=2e-33,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011129 - InterPro: IPR012340 - InterPro: IPR016027 - InterPro: IPR003029 - InterPro: IPR022967 - InterPro: IPR013223 - InterPro: IPR001900 - InterPro: IPR022966 - InterPro: IPR004476 - InterPro: IPR011805 - InterPro: IPR013668 [H]
Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]
EC number: 3.1.-.- [C]
Molecular weight: Translated: 91955; Mature: 91824
Theoretical pI: Translated: 8.59; Mature: 8.59
Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASREELAVELNIEGEEQLEALRRRLR CCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHH AMERDGQLVFTRRQCYALPERLDLLKGTVIGHRDGYGFLRVEGRKDDLYLSSEQMKTCIH HHCCCCCEEEEHHHHHHCHHHHHHHHCCEEECCCCCEEEEEECCCCCEEECHHHHHHHHC GDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTDAGVGFVVPDDSRLSFDILIPP CHHHHHHCCCCCCCCCCHHEEEEEECCCHHHHHHHHHHCCCCEEEECCCCCEEEEEEECC EDVMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNMGTGMAVDMALCTHEIPYIWPQA HHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHH VEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDARDFDDAVYCEKKRGGGWRLWVAIA HHHHHHHHHHHCCHHHHCCCCCCCCCCEEEECCCCCCCCCHHHEEECCCCCCEEEEEEEE DVSYYVRPPTPLDREARNRGTSVYFPSQVVPMLPEVLSNGLCSLNPQVDRLCMVCEMTIS CCEEEECCCCCCCHHHHCCCCEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC AKGRLTGYKFYEAVMSSHARLTYTKVWHMLQGDQDLREQYAPLVKHIEELHNLYKVLDKA CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH REERGGISFESEEAKFIFNADRRIERIEQTQRNDAHKLIEECMIMANISAARFVEKAKEP HHHHCCCCCCCCCCCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCC ALFRIHDKPTTEAITSFRSVLAELGLELPGGNKPEPRDYAELLESIADRPDAEMLQTMLL CEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH RSMKQAIYDPENRGHFGLALQSYAHFTSPIRRYPDLSLHRAIKYLLAKEQGNKGNTTETG HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC GYHYSMEEMLQLGQHCSMAERRADEATRDVSDWLKCDFMLDQVGNVFKGVIASVTGFGFF CEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH VRLDELFIDGLVHVSSLDNDYYRFDQVGQRLIGESGGQTYRLGDRVEVRVEAVNMDERKI HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEECCCEEEEEEEEECCCCHHH DFSLISSERAPRNVGKTAREKAKKGESKNAGKRRQVGKKVNFEPDSAFRGEKKAKPKAAK HHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCHHH KDARKAKKPSAKTQKIAAATKAKRAAKKKAAE HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure SQDPFQEREAEKYANPIPSREFILEHLTKREKPASREELAVELNIEGEEQLEALRRRLR CCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHH AMERDGQLVFTRRQCYALPERLDLLKGTVIGHRDGYGFLRVEGRKDDLYLSSEQMKTCIH HHCCCCCEEEEHHHHHHCHHHHHHHHCCEEECCCCCEEEEEECCCCCEEECHHHHHHHHC GDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTDAGVGFVVPDDSRLSFDILIPP CHHHHHHCCCCCCCCCCHHEEEEEECCCHHHHHHHHHHCCCCEEEECCCCCEEEEEEECC EDVMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNMGTGMAVDMALCTHEIPYIWPQA HHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHH VEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDARDFDDAVYCEKKRGGGWRLWVAIA HHHHHHHHHHHCCHHHHCCCCCCCCCCEEEECCCCCCCCCHHHEEECCCCCCEEEEEEEE DVSYYVRPPTPLDREARNRGTSVYFPSQVVPMLPEVLSNGLCSLNPQVDRLCMVCEMTIS CCEEEECCCCCCCHHHHCCCCEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC AKGRLTGYKFYEAVMSSHARLTYTKVWHMLQGDQDLREQYAPLVKHIEELHNLYKVLDKA CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH REERGGISFESEEAKFIFNADRRIERIEQTQRNDAHKLIEECMIMANISAARFVEKAKEP HHHHCCCCCCCCCCCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCC ALFRIHDKPTTEAITSFRSVLAELGLELPGGNKPEPRDYAELLESIADRPDAEMLQTMLL CEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH RSMKQAIYDPENRGHFGLALQSYAHFTSPIRRYPDLSLHRAIKYLLAKEQGNKGNTTETG HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC GYHYSMEEMLQLGQHCSMAERRADEATRDVSDWLKCDFMLDQVGNVFKGVIASVTGFGFF CEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH VRLDELFIDGLVHVSSLDNDYYRFDQVGQRLIGESGGQTYRLGDRVEVRVEAVNMDERKI HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEECCCEEEEEEEEECCCCHHH DFSLISSERAPRNVGKTAREKAKKGESKNAGKRRQVGKKVNFEPDSAFRGEKKAKPKAAK HHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCHHH KDARKAKKPSAKTQKIAAATKAKRAAKKKAAE HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7610040; 9278503; 3058695; 1400189; 9603904 [H]