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The map label for this gene is proX [H]

Identifier: 194735674

GI number: 194735674

Start: 2865607

End: 2866602

Strand: Direct

Name: proX [H]

Synonym: SeSA_A2959

Alternate gene names: 194735674

Gene position: 2865607-2866602 (Clockwise)

Preceding gene: 194733925

Following gene: 194737719

Centisome position: 60.85

GC content: 53.71

Gene sequence:

>996_bases
ATGCGACATACTGTGATATTTGCCTCAGCGTTTGCCACCCTTGTCACCGCCAGCGCTTTCGCTGCCGACCTGCCTGGCAA
AGGCATTACCGTCCAACCTATCCAAAGCACTATTTCTGAAGAGTCCTTCCAGACGTTACTGGTCAGCCGGGCGCTGGAAA
AGTTGGGTTATACCGTAAATAAGCCGAGTGAAGTCGATTACAACGTAGGCTATACCTCCATCGCCTCTGGCGATGCGACG
TTTACCGCCGTGAACTGGCAGCCGCTGCATGATGATATGTATGCCGCAGCAGGCGGAGACAAAAAGTTTTACCGCGAGGG
TGTCTTCGTCTCCGGCGCTGCGCAGGGCTATCTGATCGATAAAAAAACCGCCGAGCAGTACAACATCACCAATATCGCTC
AGCTAAAAGATCCGAAAATCGCCAAAATCTTCGATACCAATGGCGACGGAAAAGCGGACATGATGGGCTGCTCGCCGGGC
TGGGGCTGCGAAGCCGTGATCAATCACCAGAATAAAGCGTTTGATCTGCAAAAAACCGTTGAGGTCAGCCACGGTAACTA
TGCGGCGATGATGGCTGATACCATTACCCGTTTTAAAGAAGGCAAGCCGGTGCTGTATTACACCTGGACCCCGTACTGGG
TGAGCGACGTAATGAAGCCGGGTAAAGATGTCGTCTGGCTACAGGTGCCGTTCTCCTCCCTGCCGGGCGAACAGAAAAAT
ATTGATACTAAACTGCCGAACGGCGCGAACTATGGGTTCCCGGTTAATACCATGCATATTGTCGCCAATAAGGCATGGGC
GGAGAAAAACCCGGCGGCGGCGAAACTGTTCGCCATCATGAAGCTGCCGCTGGCGGATATCAACGCGCAGAACGCCATGA
TGCATGCCGGTAAATCGTCTGAAGCCGATGTTCAGGGCCATGTGGACGGCTGGATCAACGCCCACCAGCAGCAGTTTGAC
GGCTGGGTGAAAGAAGCGCTGGCCGCGCAGAAATAA

Upstream 100 bases:

>100_bases
TGGGCTAATCACCCGCCCTTTCGTTAAGTAACTCTCCTGACGCCCGGTGACGCTGCGCTTACCGGGCTTACAACTCCCTA
CCATAATTAAAGGAACAACG

Downstream 100 bases:

>100_bases
GATCGTTTTTTATGCCGGATAAGGCGCAGTTCATGCGCCGCTATCCGGCCAACGCAATCTCTCCTCAAAGCGCACGATTC
ATCACGTCACCGTTCCCCTT

Product: glycine betaine transporter periplasmic subunit

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MRHTVIFASAFATLVTASAFAADLPGKGITVQPIQSTISEESFQTLLVSRALEKLGYTVNKPSEVDYNVGYTSIASGDAT
FTAVNWQPLHDDMYAAAGGDKKFYREGVFVSGAAQGYLIDKKTAEQYNITNIAQLKDPKIAKIFDTNGDGKADMMGCSPG
WGCEAVINHQNKAFDLQKTVEVSHGNYAAMMADTITRFKEGKPVLYYTWTPYWVSDVMKPGKDVVWLQVPFSSLPGEQKN
IDTKLPNGANYGFPVNTMHIVANKAWAEKNPAAAKLFAIMKLPLADINAQNAMMHAGKSSEADVQGHVDGWINAHQQQFD
GWVKEALAAQK

Sequences:

>Translated_331_residues
MRHTVIFASAFATLVTASAFAADLPGKGITVQPIQSTISEESFQTLLVSRALEKLGYTVNKPSEVDYNVGYTSIASGDAT
FTAVNWQPLHDDMYAAAGGDKKFYREGVFVSGAAQGYLIDKKTAEQYNITNIAQLKDPKIAKIFDTNGDGKADMMGCSPG
WGCEAVINHQNKAFDLQKTVEVSHGNYAAMMADTITRFKEGKPVLYYTWTPYWVSDVMKPGKDVVWLQVPFSSLPGEQKN
IDTKLPNGANYGFPVNTMHIVANKAWAEKNPAAAKLFAIMKLPLADINAQNAMMHAGKSSEADVQGHVDGWINAHQQQFD
GWVKEALAAQK
>Mature_331_residues
MRHTVIFASAFATLVTASAFAADLPGKGITVQPIQSTISEESFQTLLVSRALEKLGYTVNKPSEVDYNVGYTSIASGDAT
FTAVNWQPLHDDMYAAAGGDKKFYREGVFVSGAAQGYLIDKKTAEQYNITNIAQLKDPKIAKIFDTNGDGKADMMGCSPG
WGCEAVINHQNKAFDLQKTVEVSHGNYAAMMADTITRFKEGKPVLYYTWTPYWVSDVMKPGKDVVWLQVPFSSLPGEQKN
IDTKLPNGANYGFPVNTMHIVANKAWAEKNPAAAKLFAIMKLPLADINAQNAMMHAGKSSEADVQGHVDGWINAHQQQFD
GWVKEALAAQK

Specific function: Member of a multicomponent binding-protein-dependent transport system (the proU transporter) which serves as the glycine betaine/L-proline transporter [H]

COG id: COG2113

COG function: function code E; ABC-type proline/glycine betaine transport systems, periplasmic components

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789034, Length=331, Percent_Identity=83.3836858006042, Blast_Score=590, Evalue=1e-170,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007210 [H]

Pfam domain/function: PF04069 OpuAC [H]

EC number: NA

Molecular weight: Translated: 36153; Mature: 36153

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHTVIFASAFATLVTASAFAADLPGKGITVQPIQSTISEESFQTLLVSRALEKLGYTVN
CCEEEEHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KPSEVDYNVGYTSIASGDATFTAVNWQPLHDDMYAAAGGDKKFYREGVFVSGAAQGYLID
CCCCCEECCCEEEECCCCEEEEEEECEECCCCHHCCCCCCHHHHHCCEEEECCCCCEEEE
KKTAEQYNITNIAQLKDPKIAKIFDTNGDGKADMMGCSPGWGCEAVINHQNKAFDLQKTV
CCCCCCCCCCCHHHCCCCCEEEEEECCCCCCEEEECCCCCCCCHHEECCCCCEECHHHEE
EVSHGNYAAMMADTITRFKEGKPVLYYTWTPYWVSDVMKPGKDVVWLQVPFSSLPGEQKN
EECCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCEEEEEECHHHCCCCCCC
IDTKLPNGANYGFPVNTMHIVANKAWAEKNPAAAKLFAIMKLPLADINAQNAMMHAGKSS
CCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCC
EADVQGHVDGWINAHQQQFDGWVKEALAAQK
CCCCEECCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRHTVIFASAFATLVTASAFAADLPGKGITVQPIQSTISEESFQTLLVSRALEKLGYTVN
CCEEEEHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KPSEVDYNVGYTSIASGDATFTAVNWQPLHDDMYAAAGGDKKFYREGVFVSGAAQGYLID
CCCCCEECCCEEEECCCCEEEEEEECEECCCCHHCCCCCCHHHHHCCEEEECCCCCEEEE
KKTAEQYNITNIAQLKDPKIAKIFDTNGDGKADMMGCSPGWGCEAVINHQNKAFDLQKTV
CCCCCCCCCCCHHHCCCCCEEEEEECCCCCCEEEECCCCCCCCHHEECCCCCEECHHHEE
EVSHGNYAAMMADTITRFKEGKPVLYYTWTPYWVSDVMKPGKDVVWLQVPFSSLPGEQKN
EECCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCEEEEEECHHHCCCCCCC
IDTKLPNGANYGFPVNTMHIVANKAWAEKNPAAAKLFAIMKLPLADINAQNAMMHAGKSS
CCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCC
EADVQGHVDGWINAHQQQFDGWVKEALAAQK
CCCCEECCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]