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The map label for this gene is 194735545

Identifier: 194735545

GI number: 194735545

Start: 2104941

End: 2105951

Strand: Direct

Name: 194735545

Synonym: SeSA_A2220

Alternate gene names: NA

Gene position: 2104941-2105951 (Clockwise)

Preceding gene: 194735913

Following gene: 194734366

Centisome position: 44.7

GC content: 61.62

Gene sequence:

>1011_bases
ATGGCGATTTATACCCGAACAGGTGACGCTGGCACCACATCACTGTTTACCGGCCAGCGGGTGAGCAAAACCCACCCGCG
GGTTGAAGCCTACGGCACGCTGGATGAGCTGAACGCCGCGCTGAGCCTGTGCGCCTGCGCCGCTGCGGATGAAAATCACC
GCACCTTACTCGAGGCCATCCAGCAGCAACTTTTTTGGTTTAGCGCAGAGCTGGCCAGCGACAGCGAGCACCCGTCGCCC
AAACAGCGCTACATCAGCAGCGAAGAGATTTCGGCCCTGGAAGCCGCTATCGATCGGGCAATGGCCCGCGTCGAACCGCT
GCACAGCTTTATTTTACCCGGACGCTGCGAAGCCGCGAGCCGATTACATTTTGCCCGCACGCTGGCGCGCCGCGCCGAAC
GCCGGCTGGTTGAGCTGGCGGCGGAAGTCAACGTACGTCAGGTGCTGATGCGCTATATCAACCGCTTATCGGACTGCCTG
TACGCCCTGGCCCGCGCGGAAGATAGCGATGCGCACCAGGCCAACATCATCCGTGAAGTTAGCAAGCGCTATCTGGCTGC
CTGCCAGCCGCCCCACAGCAAGGAGACGACGCCAGTGGCCCTCTCATTCCACGATCTGCACCAGCTCACCCGCGCCGCCG
TTGAACGCGCGCAGCAACTGCAGGTTCCGGTAGTCGTCAGCATCGTTGACGCGCACGGCACGGAAACTGTGACCTGGCGG
ATGCCGGACGCCCTGCTGGTCAGCAGCGAGCTGGCGCCGAAAAAGGCCTGGACCGCAGTGGCGATGAAAACGGCGACCCA
TGAGCTGAGCGATATCGTTCAGCCGGGCGCCGCGCTTTACGGTCTGGAAAGTCATTTACAGGGAAAAGTGGTCACCTTTG
GCGGCGGTTACGCCCTGTGGCGCGACGGCATATTAATTGGGGGTCTTGGCATCAGCGGCGGCAGCGTTGAGCAGGACATG
GACATAGCACAGACCGCCATCGCGGCTATTAACGTGGGAACACATCAATGA

Upstream 100 bases:

>100_bases
CGGCGGCTCCAGCGCCAGGCACGTTTTTTCCGGGCCAAATGAGGCCATCGACCTCGCCGTTGTCGGCATTGTAGATACGC
TTTCGCGTTAAGGGGCGGTT

Downstream 100 bases:

>100_bases
ATACTTCTGAACTCGAAACCCTGATTCGCACCATTCTTAGCGAGCAATTAACCACGCCAGCGCAAACACCGGCCCAGCCT
CAGGGCAAAGGGATTTTCCA

Product: PduO

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; ORFW [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MAIYTRTGDAGTTSLFTGQRVSKTHPRVEAYGTLDELNAALSLCACAAADENHRTLLEAIQQQLFWFSAELASDSEHPSP
KQRYISSEEISALEAAIDRAMARVEPLHSFILPGRCEAASRLHFARTLARRAERRLVELAAEVNVRQVLMRYINRLSDCL
YALARAEDSDAHQANIIREVSKRYLAACQPPHSKETTPVALSFHDLHQLTRAAVERAQQLQVPVVVSIVDAHGTETVTWR
MPDALLVSSELAPKKAWTAVAMKTATHELSDIVQPGAALYGLESHLQGKVVTFGGGYALWRDGILIGGLGISGGSVEQDM
DIAQTAIAAINVGTHQ

Sequences:

>Translated_336_residues
MAIYTRTGDAGTTSLFTGQRVSKTHPRVEAYGTLDELNAALSLCACAAADENHRTLLEAIQQQLFWFSAELASDSEHPSP
KQRYISSEEISALEAAIDRAMARVEPLHSFILPGRCEAASRLHFARTLARRAERRLVELAAEVNVRQVLMRYINRLSDCL
YALARAEDSDAHQANIIREVSKRYLAACQPPHSKETTPVALSFHDLHQLTRAAVERAQQLQVPVVVSIVDAHGTETVTWR
MPDALLVSSELAPKKAWTAVAMKTATHELSDIVQPGAALYGLESHLQGKVVTFGGGYALWRDGILIGGLGISGGSVEQDM
DIAQTAIAAINVGTHQ
>Mature_335_residues
AIYTRTGDAGTTSLFTGQRVSKTHPRVEAYGTLDELNAALSLCACAAADENHRTLLEAIQQQLFWFSAELASDSEHPSPK
QRYISSEEISALEAAIDRAMARVEPLHSFILPGRCEAASRLHFARTLARRAERRLVELAAEVNVRQVLMRYINRLSDCLY
ALARAEDSDAHQANIIREVSKRYLAACQPPHSKETTPVALSFHDLHQLTRAAVERAQQLQVPVVVSIVDAHGTETVTWRM
PDALLVSSELAPKKAWTAVAMKTATHELSDIVQPGAALYGLESHLQGKVVTFGGGYALWRDGILIGGLGISGGSVEQDMD
IAQTAIAAINVGTHQ

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=168, Percent_Identity=37.5, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI115534154, Length=166, Percent_Identity=30.1204819277108, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 36627; Mature: 36496

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIYTRTGDAGTTSLFTGQRVSKTHPRVEAYGTLDELNAALSLCACAAADENHRTLLEAI
CEEEEECCCCCCCHHCCCCCHHCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
QQQLFWFSAELASDSEHPSPKQRYISSEEISALEAAIDRAMARVEPLHSFILPGRCEAAS
HHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RLHFARTLARRAERRLVELAAEVNVRQVLMRYINRLSDCLYALARAEDSDAHQANIIREV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SKRYLAACQPPHSKETTPVALSFHDLHQLTRAAVERAQQLQVPVVVSIVDAHGTETVTWR
HHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEE
MPDALLVSSELAPKKAWTAVAMKTATHELSDIVQPGAALYGLESHLQGKVVTFGGGYALW
CCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCHHH
RDGILIGGLGISGGSVEQDMDIAQTAIAAINVGTHQ
HCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AIYTRTGDAGTTSLFTGQRVSKTHPRVEAYGTLDELNAALSLCACAAADENHRTLLEAI
EEEEECCCCCCCHHCCCCCHHCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
QQQLFWFSAELASDSEHPSPKQRYISSEEISALEAAIDRAMARVEPLHSFILPGRCEAAS
HHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RLHFARTLARRAERRLVELAAEVNVRQVLMRYINRLSDCLYALARAEDSDAHQANIIREV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SKRYLAACQPPHSKETTPVALSFHDLHQLTRAAVERAQQLQVPVVVSIVDAHGTETVTWR
HHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEE
MPDALLVSSELAPKKAWTAVAMKTATHELSDIVQPGAALYGLESHLQGKVVTFGGGYALW
CCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCHHH
RDGILIGGLGISGGSVEQDMDIAQTAIAAINVGTHQ
HCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA